IT1175508B - Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta - Google Patents

Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta

Info

Publication number
IT1175508B
IT1175508B IT21436/84A IT2143684A IT1175508B IT 1175508 B IT1175508 B IT 1175508B IT 21436/84 A IT21436/84 A IT 21436/84A IT 2143684 A IT2143684 A IT 2143684A IT 1175508 B IT1175508 B IT 1175508B
Authority
IT
Italy
Prior art keywords
protein
polideoxyribonucleotide
segment
procedure
produce
Prior art date
Application number
IT21436/84A
Other languages
English (en)
Other versions
IT8421436A1 (it
IT8421436A0 (it
Inventor
Annette Elmblad
Gunnar Palm
Staffan Josephson
Larl Olof Heden
Erik Holmgren
Original Assignee
Kabigen Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabigen Ab filed Critical Kabigen Ab
Publication of IT8421436A0 publication Critical patent/IT8421436A0/it
Publication of IT8421436A1 publication Critical patent/IT8421436A1/it
Application granted granted Critical
Publication of IT1175508B publication Critical patent/IT1175508B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
IT21436/84A 1983-06-23 1984-06-15 Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta IT1175508B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8303626A SE8303626D0 (sv) 1983-06-23 1983-06-23 A recombinant plasmid a transformant microorganism, a polydoxyrebonucleotide segment, a process for producing a biologically active protein, and the protein thus produced

Publications (3)

Publication Number Publication Date
IT8421436A0 IT8421436A0 (it) 1984-06-15
IT8421436A1 IT8421436A1 (it) 1985-12-15
IT1175508B true IT1175508B (it) 1987-07-01

Family

ID=20351747

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21436/84A IT1175508B (it) 1983-06-23 1984-06-15 Un plasmide ricombinante, un microorganismo trasformante un segmento di polideossiribonucleotide, un procedimento per produrre una proteina biologicamente attiva e la proteina cosi' prodotta

Country Status (5)

Country Link
EP (1) EP0130166A1 (it)
JP (1) JPS6019493A (it)
GB (1) GB2142033A (it)
IT (1) IT1175508B (it)
SE (1) SE8303626D0 (it)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71991A (en) * 1983-06-06 1994-05-30 Genentech Inc Preparation of human FGI and FGE in their processed form through recombinant AND tranology in prokaryotes
WO1985000831A1 (en) * 1983-08-10 1985-02-28 Amgen Microbial expression of insulin-like growth factor
GB8522977D0 (en) * 1985-09-17 1985-10-23 Fujisawa Pharmaceutical Co Production of insulin-like growth factor 1
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
US4738921A (en) * 1984-09-27 1988-04-19 Eli Lilly And Company Derivative of the tryptophan operon for expression of fused gene products
GB8507833D0 (en) * 1985-03-26 1985-05-01 Biogen Nv Production of human somatomedin c
EP0219814B1 (en) * 1985-10-21 1991-09-11 Fujisawa Pharmaceutical Co., Ltd. Process for production of isulin-like growth factor i and plasmid for production thereof
JPH0817708B2 (ja) * 1986-10-09 1996-02-28 藤沢薬品工業株式会社 Ｍｅｔ−インスリン様成長因子Ｉの発現ベクター
JPH03505966A (ja) * 1988-07-14 1991-12-26 ベイラー カレッジ オブ メディシン 生物高分子の固相組立及び再構築方法
ATE143696T1 (de) * 1989-02-28 1996-10-15 Canon Kk Partiell doppelsträngiges oligonukleotid und verfahren zu seiner bildung
JP2682738B2 (ja) * 1989-06-09 1997-11-26 グロペップ プロプライエタリー リミテッド 成長ホルモン融合蛋白質
KR920003787B1 (ko) * 1990-03-05 1992-05-14 한국과학기술 연구원 신규 플라스미드 제조 및 그를 함유한 균주를 배양하여 아이 지 에프-1(igf-1)을 생산하는 방법
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
AU3812993A (en) * 1992-03-24 1993-10-21 Synergen, Inc. Refolding and purification of insulin-like growth factor I
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
DE19940750A1 (de) 1998-08-28 2000-06-21 Febit Ferrarius Biotech Gmbh Träger für Analytbestimmungsverfahren und Verfahren zur Herstellung des Trägers
ATE334197T1 (de) 1999-02-19 2006-08-15 Febit Biotech Gmbh Verfahren zur herstellung von polymeren
AU2006242129A1 (en) 2005-05-02 2006-11-09 Genzyme Corporation Gene therapy for spinal cord disorders
PT3520823T (pt) 2005-05-02 2021-09-16 Genzyme Corp Terapia genética para distúrbios neurometabólicos
AR059089A1 (es) 2006-01-20 2008-03-12 Genzyme Corp Administracion intraventricular de una enzima para enfermedades de almacenamiento lisosomal
AR059088A1 (es) * 2006-01-20 2008-03-12 Genzyme Corp Administracion intraventricular de una proteina para esclerosis lateral amiotrofica
MX361816B (es) 2006-02-09 2018-12-17 Genzyme Corp Suministro intraventricular lento.
CN101460621B (zh) 2006-06-07 2016-01-27 建新公司 肌萎缩性侧索硬化和其他脊髓失调症的基因治疗
DK2066791T3 (da) 2006-10-03 2012-10-15 Genzyme Corp Genterapi for amyotrofisk lateralsklerose og andre rygmarvssygdomme

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) * 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone

Also Published As

Publication number Publication date
IT8421436A1 (it) 1985-12-15
JPS6019493A (ja) 1985-01-31
IT8421436A0 (it) 1984-06-15
EP0130166A1 (en) 1985-01-02
GB2142033A (en) 1985-01-09
SE8303626D0 (sv) 1983-06-23
GB8416007D0 (en) 1984-07-25

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970628