IT8521468A0 - Procedimento per ottenere interferon leucocitario alfa-2dell'uomo. - Google Patents

Procedimento per ottenere interferon leucocitario alfa-2dell'uomo.

Info

Publication number
IT8521468A0
IT8521468A0 IT8521468A IT2146885A IT8521468A0 IT 8521468 A0 IT8521468 A0 IT 8521468A0 IT 8521468 A IT8521468 A IT 8521468A IT 2146885 A IT2146885 A IT 2146885A IT 8521468 A0 IT8521468 A0 IT 8521468A0
Authority
IT
Italy
Prior art keywords
human
procedure
interferon alpha
leukocyte interferon
obtain leukocyte
Prior art date
Application number
IT8521468A
Other languages
English (en)
Other versions
IT1201429B (it
Inventor
Vladimir Georgievich Debabov
Jury Dmitrievich Tsygankov
Andrei Jurievich Chistoserdov
Evgeny Davidovich Sverdlov
Lara Semenovna Izotova
Sergei Viktorovich Kostrov
Viktor Emilievich Sterkin
Vladimir Pavlovich Kuznetsov
Sergei Vasilievich Belyaev
Galina Sergeevna Monastyrskaya
Original Assignee
Vnii Genetiki Selektsii Promy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vnii Genetiki Selektsii Promy filed Critical Vnii Genetiki Selektsii Promy
Publication of IT8521468A0 publication Critical patent/IT8521468A0/it
Application granted granted Critical
Publication of IT1201429B publication Critical patent/IT1201429B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT21468/85A 1984-07-13 1985-07-08 Procedimento per ottenere interferon leucocitario alfa-2 dell'uomo IT1201429B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU843757952A SU1364343A1 (ru) 1984-07-13 1984-07-13 Способ получени человеческого лейкоцитарного интерферона альфа-2

Publications (2)

Publication Number Publication Date
IT8521468A0 true IT8521468A0 (it) 1985-07-08
IT1201429B IT1201429B (it) 1989-02-02

Family

ID=21125646

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21468/85A IT1201429B (it) 1984-07-13 1985-07-08 Procedimento per ottenere interferon leucocitario alfa-2 dell'uomo

Country Status (12)

Country Link
US (1) US4680260A (it)
JP (1) JPS6156093A (it)
BG (1) BG46981A1 (it)
CA (1) CA1264294A (it)
CH (1) CH666051A5 (it)
DE (1) DE3524991A1 (it)
FR (1) FR2567540B1 (it)
GB (1) GB2163750B (it)
HU (1) HU194316B (it)
IN (1) IN162268B (it)
IT (1) IT1201429B (it)
SU (1) SU1364343A1 (it)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
SU1703690A1 (ru) * 1986-04-30 1992-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Рекомбинантна плазмидна ДНК @ 22, кодирующа синтез интерферона @ -11 человека, и штамм бактерии РSеUDомоNаS Sp. -продуцент- интерферона @ -11 человека
RU2142508C1 (ru) * 1997-07-23 1999-12-10 Государственный научный центр вирусологии и биотехнологии "Вектор" Способ промышленного получения полипептида с биологической активностью лейкоцитарного интерферона альфа-2 человека
RU2140284C1 (ru) * 1998-07-06 1999-10-27 Государственное унитарное предприятие "Иммунопрепарат" Способ получения человеческого лейкоцитарного интерферона
WO2002079453A2 (en) * 2001-03-30 2002-10-10 The National Food Research Institute Method for increasing the production of a secondary metabolite in a microorganism by introducing mutations that confer antibiotic-resistance
RU2203950C1 (ru) * 2002-01-15 2003-05-10 Общество с ограниченной ответственностью "Биотех" Штамм дрожжей pichia pastoris - продуцент лейкоцитарного интерферона-16 человека, рекомбинантная плазмидная днк phin и способ ее конструирования
RU2225722C1 (ru) * 2002-07-11 2004-03-20 Государственный научно-исследовательский институт особо чистых биопрепаратов Способ получения человеческого интерферона
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
RU2242516C1 (ru) * 2003-12-18 2004-12-20 Общество С Ограниченной Ответственностью "Фармапарк" Способ получения рекомбинантного человеческого интерферона альфа-2b, рекомбинантная плазмида и штамм продуцент для его осуществления
ES2663594T3 (es) * 2004-01-16 2018-04-16 Pfenex Inc Expresión de proteínas de mamífero en Pseudomonas fluorescens
US8603824B2 (en) 2004-07-26 2013-12-10 Pfenex, Inc. Process for improved protein expression by strain engineering
JP5444553B2 (ja) 2007-04-27 2014-03-19 フェネックス インコーポレイテッド 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および／または質が改善されている特定の株を同定する方法
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
UA100692C2 (ru) 2007-05-02 2013-01-25 Мериал Лимитед Днк-плазмиды, имеющие повышенную экспрессию и стабильность
MX2010005858A (es) 2007-11-28 2010-06-11 Univ Pennsylvania Adenovirus e simianos sadv-39, sadv-25.2, sadv-26, sadv-30, sadv-37 y sadv-38.
WO2012071318A2 (en) 2010-11-23 2012-05-31 The Trustees Of The University Of Pennsylvania Subfamily e simian adenoviruses a1321, a1325, a1295, a1309, a1316 and a1322 and uses thereof
WO2013173702A2 (en) 2012-05-18 2013-11-21 The Trustees Of The University Of Pennsylvania Subfamily e simian adenoviruses a1302, a1320, a1331 and a1337 and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE870188A (fr) * 1977-09-08 1979-03-05 Ici Ltd Procede microbiologique
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
DE3176011D1 (en) * 1980-06-12 1987-04-23 Japan Found Cancer Plasmid
CH657141A5 (de) * 1980-07-01 1986-08-15 Hoffmann La Roche Dns-sequenzen, rekombinante expressionsvektoren zur mikrobiellen herstellung von human-leukozyten-interferonen und transformierte mikroorganismen.
DE3280127D1 (de) * 1981-03-27 1990-04-12 Ici Plc Genetisch modifizierte mikroorganismen.
DE3122216A1 (de) * 1981-06-04 1982-12-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung eines mikroorganismus, welcher (alpha)-galactosidase, aber keine invertase bildet, so erhaltener mikroorganismus und seine verwendung
IE54046B1 (en) * 1981-08-25 1989-05-24 Celltech Ltd Expression vectors
FR2516094A1 (fr) * 1981-11-06 1983-05-13 Wellcome Found Vecteur de clonage recombinant, micro-organisme transforme par ce vecteur, bacteriophage et procede pour produire un polypeptide heterologue
CA1210714A (en) * 1982-03-23 1986-09-02 Alan Sloma .alpha.-INTERFERON GX-1
NZ207925A (en) * 1983-04-25 1988-05-30 Genentech Inc Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture

Also Published As

Publication number Publication date
BG46981A1 (en) 1990-04-16
SU1364343A1 (ru) 1988-01-07
CA1264294A (en) 1990-01-09
GB8517795D0 (en) 1985-08-21
IT1201429B (it) 1989-02-02
US4680260A (en) 1987-07-14
GB2163750B (en) 1987-09-16
FR2567540A1 (fr) 1986-01-17
GB2163750A (en) 1986-03-05
IN162268B (it) 1988-04-23
DE3524991A1 (de) 1986-03-13
JPS6156093A (ja) 1986-03-20
CH666051A5 (de) 1988-06-30
HUT39476A (en) 1986-09-29
HU194316B (en) 1988-01-28
FR2567540B1 (fr) 1988-10-14

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Effective date: 19970730