IT1180507B - Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento - Google Patents

Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento

Info

Publication number
IT1180507B
IT1180507B IT03511/84A IT351184A IT1180507B IT 1180507 B IT1180507 B IT 1180507B IT 03511/84 A IT03511/84 A IT 03511/84A IT 351184 A IT351184 A IT 351184A IT 1180507 B IT1180507 B IT 1180507B
Authority
IT
Italy
Prior art keywords
etofibrate
microgranules
procedure
sieving
equal
Prior art date
Application number
IT03511/84A
Other languages
English (en)
Other versions
IT8403511A0 (it
Inventor
Roberto Valducci
Original Assignee
Roberto Valducci
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roberto Valducci filed Critical Roberto Valducci
Publication of IT8403511A0 publication Critical patent/IT8403511A0/it
Priority to IT03511/84A priority Critical patent/IT1180507B/it
Priority to AT85830154T priority patent/ATE77052T1/de
Priority to EP85830154A priority patent/EP0168360B1/en
Priority to DE8585830154T priority patent/DE3586185T2/de
Priority to JP13707785A priority patent/JPS6133113A/ja
Priority to ES544649A priority patent/ES8701494A1/es
Priority to SU853917801A priority patent/RU1829934C/ru
Priority to KR1019850004644A priority patent/KR870001959B1/ko
Application granted granted Critical
Publication of IT1180507B publication Critical patent/IT1180507B/it
Priority to US07/247,914 priority patent/US4957746A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT03511/84A 1984-06-29 1984-06-29 Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento IT1180507B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT03511/84A IT1180507B (it) 1984-06-29 1984-06-29 Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento
AT85830154T ATE77052T1 (de) 1984-06-29 1985-06-19 Verfahren zur herstellung von etofibrat oder aehnliche verbindungen enthaltende mikrogranula mit verzoegerter freisetzung sowie die auf diese weise erhaltenen produkte.
EP85830154A EP0168360B1 (en) 1984-06-29 1985-06-19 Process for preparing etofibrate or similar compounds containing sustained release microgranules and products thus obtained
DE8585830154T DE3586185T2 (de) 1984-06-29 1985-06-19 Verfahren zur herstellung von etofibrat oder aehnliche verbindungen enthaltende mikrogranula mit verzoegerter freisetzung sowie die auf diese weise erhaltenen produkte.
JP13707785A JPS6133113A (ja) 1984-06-29 1985-06-25 エトフイブレ−ト又は類似化合物含有遅延放出微小顆粒の製造方法及びその製品
ES544649A ES8701494A1 (es) 1984-06-29 1985-06-27 Procedimiento para la preparacion de etofibrato o compuestossimilares que contienen microgranulos de liberacion constan-te
SU853917801A RU1829934C (ru) 1984-06-29 1985-06-28 Способ получени микрогранул этофибрата
KR1019850004644A KR870001959B1 (ko) 1984-06-29 1985-06-28 에토피브레이트 화합물을 함유하는 서방형 과립의 제조방법
US07/247,914 US4957746A (en) 1984-06-29 1988-09-22 Process for preparing etofibrate or similar compounds containing sustained release microgranules and products thus obtained

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03511/84A IT1180507B (it) 1984-06-29 1984-06-29 Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento

Publications (2)

Publication Number Publication Date
IT8403511A0 IT8403511A0 (it) 1984-06-29
IT1180507B true IT1180507B (it) 1987-09-23

Family

ID=11108749

Family Applications (1)

Application Number Title Priority Date Filing Date
IT03511/84A IT1180507B (it) 1984-06-29 1984-06-29 Procedimento per la preparazione di etofibrato o sostanze di pari o simili caratteristiche, in microgunuli-ritardo e prodotto ottenuto con tale procedimento

Country Status (9)

Country Link
US (1) US4957746A (it)
EP (1) EP0168360B1 (it)
JP (1) JPS6133113A (it)
KR (1) KR870001959B1 (it)
AT (1) ATE77052T1 (it)
DE (1) DE3586185T2 (it)
ES (1) ES8701494A1 (it)
IT (1) IT1180507B (it)
RU (1) RU1829934C (it)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4021678C2 (de) * 1990-07-07 1994-07-07 Merz & Co Gmbh & Co Verfahren zur Herstellung klein dimensionierter Formkörper mit hohem Etofibrat-Gehalt und kontrollierter Wirkstoff-Freisetzung, deren Verwendung und daraus bestehende oral verabreichbare Applikationsformen
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
DE4317127A1 (de) * 1993-05-19 1994-11-24 Merz & Co Gmbh & Co Verwendung von Etofibrat und pharmazeutische Zusammensetzungen, enthaltend Etofibrat, zur Behandlung der diabetischen Angio- und Retinopathie
FR2758461A1 (fr) * 1997-01-17 1998-07-24 Pharma Pass Composition pharmaceutique presentant une biodisponibilite elevee et son procede de preparation
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US6814977B1 (en) 1998-12-18 2004-11-09 Abbott Laboratories Formulations comprising lipid-regulating agents
US6838091B2 (en) * 1998-12-18 2005-01-04 Abbott Laboratories Formulations comprising lipid-regulating agents
US7014864B1 (en) 1998-12-18 2006-03-21 Abbott Laboratories Formulations comprising lipid-regulating agents
US6368622B2 (en) 1999-01-29 2002-04-09 Abbott Laboratories Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption
US6719999B2 (en) 1999-03-31 2004-04-13 Abbott Laboratories Formulations comprising lipid-regulating agents
JP2003500439A (ja) * 1999-05-28 2003-01-07 アボット・ラボラトリーズ 脂質調節剤を含む新規調合物
US6372251B2 (en) 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
FR2816507B1 (fr) * 2000-11-16 2003-02-28 Ethypharm Lab Prod Ethiques Microgranules a base de principe actif, procede de fabrication et compositons pharmaceutiques integrant lesdits microgranules
CN101961324A (zh) * 2010-09-10 2011-02-02 武汉药谷生物工程有限公司 一种依托贝特缓释胶囊的处方及制备方法
CN102579366A (zh) * 2012-03-23 2012-07-18 南京泽恒医药技术开发有限公司 一种依托贝特缓释微丸的制备方法
CN105769767A (zh) * 2016-04-12 2016-07-20 武汉理工大学 依托贝特自乳化制剂及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4000254A (en) * 1966-04-25 1976-12-28 Schmid Laboratories, Inc. Fungimycin compositions
US4064230A (en) * 1966-04-25 1977-12-20 Schmid Laboratories, Inc. Polyenic macrolide compositions
US4321263A (en) * 1980-09-30 1982-03-23 Rowell Laboratories, Inc. Psyllium compositions
FR2494112B1 (it) * 1980-11-19 1986-01-10 Laruelle Claude
GB2115409B (en) * 1982-02-24 1985-08-07 Zyma Sa Novel crystal modifications of (+)-catechin

Also Published As

Publication number Publication date
EP0168360A2 (en) 1986-01-15
DE3586185D1 (de) 1992-07-16
IT8403511A0 (it) 1984-06-29
JPS6133113A (ja) 1986-02-17
EP0168360A3 (en) 1987-01-07
EP0168360B1 (en) 1992-06-10
ATE77052T1 (de) 1992-06-15
KR860000069A (ko) 1986-01-25
US4957746A (en) 1990-09-18
KR870001959B1 (ko) 1987-10-23
RU1829934C (ru) 1993-07-23
ES8701494A1 (es) 1986-12-16
ES544649A0 (es) 1986-12-16
DE3586185T2 (de) 1993-01-21

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970627