IT1215675B - E suo uso. terreno di coltura esente da siero - Google Patents

E suo uso. terreno di coltura esente da siero

Info

Publication number
IT1215675B
IT1215675B IT1902488A IT1902488A IT1215675B IT 1215675 B IT1215675 B IT 1215675B IT 1902488 A IT1902488 A IT 1902488A IT 1902488 A IT1902488 A IT 1902488A IT 1215675 B IT1215675 B IT 1215675B
Authority
IT
Italy
Prior art keywords
growth
growth medium
serum free
free culture
edta
Prior art date
Application number
IT1902488A
Other languages
English (en)
Other versions
IT8819024A0 (it
Inventor
Kjell Bertheussen
Original Assignee
Medi Cult A S Oslo Norvegia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medi Cult A S Oslo Norvegia filed Critical Medi Cult A S Oslo Norvegia
Publication of IT8819024A0 publication Critical patent/IT8819024A0/it
Application granted granted Critical
Publication of IT1215675B publication Critical patent/IT1215675B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018Culture media for cell or tissue culture
    • C12N5/0037Serum-free medium, which may still contain naturally-sourced components
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/12Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14Calcium; Ca chelators; Calcitonin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00Specific components of cell culture medium
    • C12N2500/05Inorganic components
    • C12N2500/10Metals; Metal chelators
    • C12N2500/20Transition metals
    • C12N2500/24Iron; Fe chelators; Transferrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IT1902488A 1987-01-09 1988-01-08 E suo uso. terreno di coltura esente da siero IT1215675B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO870095A NO162160C (no) 1987-01-09 1987-01-09 Serumfritt vekstmedium, samt anvendelse derav.

Publications (2)

Publication Number Publication Date
IT8819024A0 IT8819024A0 (it) 1988-01-08
IT1215675B true IT1215675B (it) 1990-02-22

Family

ID=19889567

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1902488A IT1215675B (it) 1987-01-09 1988-01-08 E suo uso. terreno di coltura esente da siero

Country Status (16)

Country Link
US (2) US5045467A (it)
EP (1) EP0274445B1 (it)
JP (2) JPH0697996B2 (it)
KR (1) KR880009124A (it)
AT (1) ATE92098T1 (it)
AU (1) AU596491B2 (it)
BR (1) BR8800040A (it)
CA (1) CA1321961C (it)
DE (1) DE3882540T2 (it)
DK (1) DK169765B1 (it)
ES (1) ES2008411A6 (it)
FI (1) FI87230C (it)
IL (1) IL85026A (it)
IT (1) IT1215675B (it)
NO (1) NO162160C (it)
NZ (1) NZ223139A (it)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1307486C (en) * 1987-10-29 1992-09-15 Michael T. Largen Hybridoma production
SE8801537D0 (sv) * 1988-04-26 1988-04-26 Ellco Food Ab Cellodlingsmedium samt forfarande for dess framstellning
JPH03180175A (ja) * 1989-12-07 1991-08-06 Snow Brand Milk Prod Co Ltd 無血清培地
US5378612A (en) * 1990-05-11 1995-01-03 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Culture medium for production of recombinant protein
WO1993000423A1 (en) * 1991-06-21 1993-01-07 Novo Nordisk A/S Iron chelate culture medium additive
GB9215834D0 (en) * 1992-07-24 1992-09-09 Celltech Ltd Cell culture
DE4313620A1 (de) * 1993-04-26 1994-10-27 Biotechnolog Forschung Gmbh Hamsterzellinien und Verfahren zur Glykoproteingewinnung
US5434185A (en) * 1993-05-17 1995-07-18 The University Of Kentucky Research Foundation Method for inhibiting angiogenesis with aurintricarboxylic acid, its analogues or salts
US5405772A (en) * 1993-06-18 1995-04-11 Amgen Inc. Medium for long-term proliferation and development of cells
US6037174A (en) * 1993-08-23 2000-03-14 Nexell Therapeutics, Inc. Preparation of serum-free suspensions of human hematopoietic cells or precursor cells
US5846529A (en) * 1993-08-23 1998-12-08 Nexell Therapeutics, Inc. Infusion of neutrophil precursors for treatment of neutropenia
US5395822A (en) * 1993-09-20 1995-03-07 Izumi; Yukitoshi Use of pyruvate to prevent neuronal degeneration associated with ischemia
US5593880A (en) * 1994-02-10 1997-01-14 Viratest International, Inc. Dual-state nutritional medium for the transport and maintenance of cells
US5908782A (en) * 1995-06-05 1999-06-01 Osiris Therapeutics, Inc. Chemically defined medium for human mesenchymal stem cells
JP2000507812A (ja) * 1996-03-12 2000-06-27 ライフ テクノロジーズ,インコーポレイテッド 造血細胞培養栄養補充成分
US6043092A (en) * 1996-03-18 2000-03-28 University Of Pittsburgh Cell culture media for mammalian cells
US6511848B2 (en) * 1996-04-17 2003-01-28 Winfried Albert Process for producing and multiplying lymphocytes
EP2243827B2 (en) * 1996-08-30 2017-11-22 Life Technologies Corporation Serum-free mammalian cell culture medium, and uses thereof
GB9625175D0 (en) * 1996-12-04 1997-01-22 Medi Cult As Serum-free cell culture media
US6833271B2 (en) * 1996-12-04 2004-12-21 Medi-Cult A/S Serum-free cell culture media
US5804420A (en) * 1997-04-18 1998-09-08 Bayer Corporation Preparation of recombinant Factor VIII in a protein free medium
AU2878200A (en) * 1999-02-11 2000-08-29 Schepens Eye Research Institute, Inc., The Growth medium for human corneal endothelial cells
US6767741B1 (en) 1999-08-27 2004-07-27 Invitrogen Corporation Metal binding compounds and their use in cell culture medium compositions
JP4972261B2 (ja) * 1999-08-27 2012-07-11 ライフ テクノロジーズ コーポレーション 金属結合化合物および細胞培養培地組成物中でのそれらの使用
GB0003231D0 (en) * 2000-02-11 2000-04-05 Medi Cult As Cell culture media
US20030096414A1 (en) 2001-03-27 2003-05-22 Invitrogen Corporation Culture medium for cell growth and transfection
US20040161817A1 (en) * 2001-06-04 2004-08-19 Corixa Corporation Compositions and methods for high-level, large-scale production of recombinant proteins
US7087369B2 (en) * 2003-12-17 2006-08-08 The Regents Of The University Of California Cornea preservation medium
US20080096800A1 (en) * 2004-03-12 2008-04-24 Biodel, Inc. Rapid mucosal gel or film insulin compositions
US20080085298A1 (en) * 2004-03-12 2008-04-10 Biodel, Inc. Rapid Mucosal Gel or Film Insulin Compositions
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
US8273553B2 (en) 2004-11-02 2012-09-25 Ares Trading S.A. Production of growth hormone in serum-free cell culture medium for mammalian cells
JP4833991B2 (ja) 2004-11-02 2011-12-07 アレス トレーディング ソシエテ アノニム 哺乳動物細胞のための無血清細胞培養培地
DK2368975T3 (en) 2004-12-23 2015-01-05 Medimmune Llc Non-tumorigenic MDCK cell line for the propagation of viruses
DK1917276T3 (en) 2005-08-26 2018-05-07 Ares Trading Sa Process for Preparation of Glycosylated Interferon Beta
JP4385076B2 (ja) 2006-01-13 2009-12-16 独立行政法人科学技術振興機構 動物細胞を無血清培養するための培地用添加剤、キット及びこれらの利用
KR101495549B1 (ko) * 2006-07-13 2015-02-25 와이어쓰 엘엘씨 당단백질의 생산
KR101464783B1 (ko) 2006-09-15 2014-11-26 메디뮨 엘엘씨 높은 역가로 바이러스 증식을 지원하는 mdck 세포주 및 이를 이용한 생물반응기 공정
WO2009032040A1 (en) 2007-08-29 2009-03-12 Millipore Corporation Serum-free growth medium for acholeplasma laidlawii and methods for retention testing sterilizing grade filters
KR20110074563A (ko) 2008-09-24 2011-06-30 메디뮨 엘엘씨 바이러스의 정제 방법
WO2010055616A1 (ja) * 2008-11-11 2010-05-20 独立行政法人科学技術振興機構 分化誘導培地用添加剤およびその利用
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
JP5804385B2 (ja) 2010-03-10 2015-11-04 株式会社ツーセル 間葉系幹細胞を含む細胞製剤及びその製造方法
BR112014027378A2 (pt) 2012-05-02 2017-06-27 Life Technologies Corp expressão transiente de alto rendimento em células de mamíferos usando pareamento exclusivo de crescimento de alta densidade e meio de transfecção e potenciadores de expressão
CN106459180A (zh) * 2014-03-23 2017-02-22 爱德技术生物科学有限公司 在铜使用下重组蛋白表达的增强
TW201630622A (zh) 2014-12-16 2016-09-01 美國禮來大藥廠 速效胰島素組合物
US10119117B2 (en) 2016-01-28 2018-11-06 Nanogen Pharmaceutical Biotechnology Co., Ltd Universal, glycosylation enhancer, completely chemically defined medium formulation
KR102604992B1 (ko) * 2017-03-31 2023-11-24 베링거 인겔하임 인터내셔날 게엠베하 관류 배지
CN110835622B (zh) * 2018-08-16 2021-04-27 上海药明生物技术有限公司 用于调节哺乳动物细胞乳酸代谢的培养基及其应用
WO2025033487A1 (ja) * 2023-08-09 2025-02-13 国立研究開発法人産業技術総合研究所 血清または血清代替物の品質管理方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4466917A (en) * 1981-02-12 1984-08-21 New York University Malaria vaccine
US4544632A (en) * 1981-06-12 1985-10-01 Yuichi Yamamura Human T cell lines and method of producing same
IL65765A (en) * 1982-05-13 1985-09-29 Israel State Method of preventing virus replication in plants
US4604284A (en) * 1983-09-20 1986-08-05 Hoffmann-La Roche Inc. Homogeneous immune interferon fragment
DE3584902D1 (de) * 1984-02-29 1992-01-30 Asahi Chemical Ind Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren.
JPS6158584A (ja) * 1984-08-30 1986-03-25 Ube Ind Ltd 細胞増殖促進剤及び細胞増殖促進方法
JP2967117B2 (ja) * 1989-03-14 1999-10-25 旭化成工業株式会社 電子線硬化型導電性ペースト組成物

Also Published As

Publication number Publication date
CA1321961C (en) 1993-09-07
DK169765B1 (da) 1995-02-20
FI87230B (fi) 1992-08-31
IT8819024A0 (it) 1988-01-08
NO162160B (no) 1989-08-07
JPH0697996B2 (ja) 1994-12-07
NZ223139A (en) 1991-09-25
DK678687A (da) 1988-07-10
FI87230C (fi) 1992-12-10
FI875793L (fi) 1988-07-10
NO870095D0 (no) 1987-01-09
AU596491B2 (en) 1990-05-03
ATE92098T1 (de) 1993-08-15
AU1011588A (en) 1988-07-14
JP2524313B2 (ja) 1996-08-14
US5045454A (en) 1991-09-03
US5045467A (en) 1991-09-03
EP0274445B1 (en) 1993-07-28
EP0274445A3 (en) 1989-12-13
IL85026A (en) 1992-09-06
JPH06292570A (ja) 1994-10-21
NO162160C (no) 1989-11-15
ES2008411A6 (es) 1989-07-16
NO870095L (no) 1988-07-11
BR8800040A (pt) 1988-08-02
EP0274445A2 (en) 1988-07-13
IL85026A0 (en) 1988-06-30
DE3882540D1 (de) 1993-09-02
DE3882540T2 (de) 1993-11-18
FI875793A0 (fi) 1987-12-31
JPS63279786A (ja) 1988-11-16
DK678687D0 (da) 1987-12-22
KR880009124A (ko) 1988-09-14

Similar Documents

Publication Publication Date Title
NO870095L (no) Serumfritt vekstmedium, samt anvendelse derav.
GR3018228T3 (en) Homogeneous mammalian hematopoietic stem cell composition.
NO147213C (no) Tripeptider for anvendelse som kromogene h.h.v. fluorescerende substrater ved enzymatiske bestemmelser
GB1361523A (en) Reagent composition for the detection of nitrite
FR2455050B1 (it)
ATE44621T1 (de) Proteinkonjugate von penicillosaeure, ihre herstellung und verwendung.
JPS5217008A (en) Cassette tape recorder
JPS5434810A (en) Recording inspection system in magnetic recorder
ES542143A0 (es) Procedimiento para obtener un cultivo celular
JPS5252617A (en) Optimum recording and playback state setting method
EP0314496A3 (en) Improved hybridoma production
GB1504263A (en) Derivatives of folic acid and isotopically labelled substitution products thereof
JPS5333106A (en) Magnetic
ES8501379A1 (es) Procedimiento para preparar derivados de oxazolinio
EP0160852A3 (en) Medium for arginine decarboxylation test
JPS536527A (en) Magnetic recording reproduction system
JPS53110357A (en) Sweep control circuit for carrier reproducing circuit
ES8708219A1 (es) Un procedimiento para la preparacion de oxetanonas
JPS5288009A (en) Magnetic recording and reproduction apparatus
JPS5287007A (en) Erasing system for magnetic recording signals
ES471606A2 (es) Mejoras introducidas en el objeto de la patente principal, num. 450.300, presentada el 30 de julio de 1976, por: proce-dimiento de preparacion de derivados a-fenil-bencilidenicos de aminoacidos
ES468771A1 (es) Procedimiento para preparar acido 2-amino-1,3-benzotiazol-5-sulfonico.
JPS51150906A (en) Unattended telephone
JPS5377606A (en) Magnetic recorder and reproducer
JPS51135504A (en) Magnetic tape selecting circuit for magnetic recording reproduction de vice

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960130