IT1256111B - Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica - Google Patents

Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica

Info

Publication number
IT1256111B
IT1256111B ITMI922674A ITMI922674A IT1256111B IT 1256111 B IT1256111 B IT 1256111B IT MI922674 A ITMI922674 A IT MI922674A IT MI922674 A ITMI922674 A IT MI922674A IT 1256111 B IT1256111 B IT 1256111B
Authority
IT
Italy
Prior art keywords
cicatrizing
salts
traumatic acid
antibacterial activity
bacteriostatic
Prior art date
Application number
ITMI922674A
Other languages
English (en)
Inventor
Valle Francesco Della
Silvana Lorenzi
Gabriele Marcolongo
Original Assignee
Lifegroup Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lifegroup Spa filed Critical Lifegroup Spa
Publication of ITMI922674A0 publication Critical patent/ITMI922674A0/it
Priority to ITMI922674A priority Critical patent/IT1256111B/it
Priority to DK93118531.8T priority patent/DK0599188T3/da
Priority to AT93118531T priority patent/ATE156354T1/de
Priority to EP93118531A priority patent/EP0599188B1/en
Priority to ES93118531T priority patent/ES2106942T3/es
Priority to DE69312870T priority patent/DE69312870T2/de
Priority to CA002109537A priority patent/CA2109537A1/en
Priority to US08/155,153 priority patent/US5567716A/en
Priority to JP5317322A priority patent/JPH072725A/ja
Publication of ITMI922674A1 publication Critical patent/ITMI922674A1/it
Application granted granted Critical
Publication of IT1256111B publication Critical patent/IT1256111B/it
Priority to GR970402713T priority patent/GR3025074T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)

Abstract

Sali dell'acido traumatico di formula generale (I), in cui B è un catione farmaceuticamente attivo scelto tra:a) un ammonio quaternario b) una ammina primaria, secondaria e terziaria c) il catione di argento o zinco aventi attività cicatrizzante, disinfettante e batteriostatica e relative composizioni farmaceutiche somministrabili topicamente e per via parenterale per il trattamento terapeutico delle patologie cutanee nelle quali accanto all'effetto cicatrizzante è importante associare un effetto disinfettante, antisettico e battereostatico.
ITMI922674A 1992-11-23 1992-11-23 Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica IT1256111B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ITMI922674A IT1256111B (it) 1992-11-23 1992-11-23 Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica
ES93118531T ES2106942T3 (es) 1992-11-23 1993-11-18 Sales de acidos trans y cis traumaticos que tienen actividad cicatrizante asociada a actividad bacterioestatica, antivirica, antibiotica o antifungica.
AT93118531T ATE156354T1 (de) 1992-11-23 1993-11-18 Salze der cis und trans-traumatinsäure mit wundheilender sowie bacteriostatischer, antiviraler, antibiotischer oder fungizider wirkung
EP93118531A EP0599188B1 (en) 1992-11-23 1993-11-18 Trans and CIS traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity
DK93118531.8T DK0599188T3 (da) 1992-11-23 1993-11-18 Trans- og cis-traumatinsyresalte med sårhelende virkning associeret med bakteriostatiske, antivirale, antibiotiske eller antifungale virkninger
DE69312870T DE69312870T2 (de) 1992-11-23 1993-11-18 Salze der CIS und Trans-Traumatinsäure mit wundheilender sowie bacteriostatischer, antiviraler, antibiotischer oder fungizider Wirkung
CA002109537A CA2109537A1 (en) 1992-11-23 1993-11-19 Trans and cis traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity
US08/155,153 US5567716A (en) 1992-11-23 1993-11-19 Trans and cis traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity
JP5317322A JPH072725A (ja) 1992-11-23 1993-11-24 静菌活性、抗ウィルス活性、抗生物質活性及び抗真菌活性に関連した瘢痕形成活性を有するトランス及びシス型のトラウマチン酸塩
GR970402713T GR3025074T3 (en) 1992-11-23 1997-10-16 Trans and CIS traumatic acid salts having cicatrizant activity associated to bacteriostatic, antiviral, antibiotic or antifungal activity.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922674A IT1256111B (it) 1992-11-23 1992-11-23 Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica

Publications (3)

Publication Number Publication Date
ITMI922674A0 ITMI922674A0 (it) 1992-11-23
ITMI922674A1 ITMI922674A1 (it) 1994-05-23
IT1256111B true IT1256111B (it) 1995-11-28

Family

ID=11364331

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI922674A IT1256111B (it) 1992-11-23 1992-11-23 Sali dell'acido traumatico ad attivita' cicatrizzante ed antibatterica

Country Status (10)

Country Link
US (1) US5567716A (it)
EP (1) EP0599188B1 (it)
JP (1) JPH072725A (it)
AT (1) ATE156354T1 (it)
CA (1) CA2109537A1 (it)
DE (1) DE69312870T2 (it)
DK (1) DK0599188T3 (it)
ES (1) ES2106942T3 (it)
GR (1) GR3025074T3 (it)
IT (1) IT1256111B (it)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US7137968B1 (en) 2000-03-13 2006-11-21 Nucryst Pharmaceuticals Corp. Transcutaneous medical device dressings and method of use
US6719987B2 (en) 2000-04-17 2004-04-13 Nucryst Pharmaceuticals Corp. Antimicrobial bioabsorbable materials
FR2809310B1 (fr) * 2000-05-26 2004-02-13 Centre Nat Rech Scient Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
US20030185901A1 (en) 2000-07-27 2003-10-02 Burrell Robert E. Methods of treating conditions with a metal-containing material
US7427416B2 (en) 2000-07-27 2008-09-23 Nucryst Pharmaceuticals Corp. Methods of treating conditions using metal-containing materials
US20030180379A1 (en) 2000-07-27 2003-09-25 Burrell Robert E. Solutions and aerosols of metal-containing compounds
US6939568B2 (en) 2001-04-23 2005-09-06 Nucryst Pharmaceuticals Corp. Treatment of inflammatory skin conditions
US7008647B2 (en) 2001-04-23 2006-03-07 Nucryst Pharmaceuticals Corp. Treatment of acne
ATE282420T1 (de) 2000-07-27 2004-12-15 Nucryst Pharm Corp Verwendung von edelmetallen zur herstellung eines arzneitmittels zur behandlung von hyperproliferativen hautstörungen und krankheiten
US6989157B2 (en) 2000-07-27 2006-01-24 Nucryst Pharmaceuticals Corp. Dry powders of metal-containing compounds
US7001617B2 (en) 2001-04-23 2006-02-21 Nueryst Pharmaceuticals Corp. Method of induction of apoptosis and inhibition of matrix metalloproteinases using antimicrobial metals
US7255881B2 (en) 2000-07-27 2007-08-14 Nucryst Pharmaceuticals Corp. Metal-containing materials
KR100447825B1 (ko) * 2001-11-23 2004-09-08 주식회사 코리아나화장품 트라마트산을 포함하는 콜라겐 생합성 촉진용 화장료 조성물
US20030133893A1 (en) * 2002-01-15 2003-07-17 Degania Silicone Ltd. Compositions and methods for treating skin ailments
US7201925B2 (en) 2002-04-23 2007-04-10 Nueryst Pharmaceuticals Corp. Treatment of ungual and subungual diseases
US7258875B2 (en) * 2003-12-04 2007-08-21 Chiou Consulting, Inc. Compositions and methods for topical treatment of skin infection
ES2392436T3 (es) 2005-04-19 2012-12-10 Innovet Italia S.R.L. Composiciones farmacéuticas para el tratamiento de ulceraciones crónicas
WO2009085651A1 (en) 2007-12-20 2009-07-09 Nucryst Pharmaceuticals Corp. Metal carbonate particles for use in medicine and methods of making thereof
KR20110082601A (ko) * 2008-12-19 2011-07-19 피너클 파마수티칼스, 인코포레이티드 페나조피리딘 화합물
ITPI20090027A1 (it) * 2009-03-12 2010-09-13 Filippo Lulli Sali fisiologicamente e biologicamente attivi dell'acido cis-e trans-traumatico per il trattamento di piante monocotiledoni e dicotiledoni
GB201313423D0 (en) 2013-07-26 2013-09-11 Innospec Ltd Compositions and methods
ES3011983T3 (en) * 2018-12-06 2025-04-08 Int Flavors & Fragrances Inc Traumatic acid compositions and methods for taste modulation
US20210368837A1 (en) * 2018-12-06 2021-12-02 International Flavors & Fragrances Inc. Boehmeria nivea compositions and methods for taste modulation
CN113712950A (zh) * 2021-08-31 2021-11-30 上海市同仁医院 创伤酸在制备抗肥胖药物或抗肥胖保健品中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3532636A (en) * 1968-02-14 1970-10-06 Purex Corp Ltd Detergent composition
US3542826A (en) * 1968-03-22 1970-11-24 Purex Corp Ltd Cobalt dodecenedioate and use thereof
US3808314A (en) * 1970-01-22 1974-04-30 Purex Corp Ltd Cobalt dodecenedioate for treating canine pyometritis
US3720773A (en) * 1970-01-22 1973-03-13 Purex Corp Ltd Method and composition for the topical treatment of herpetic keratitis

Also Published As

Publication number Publication date
CA2109537A1 (en) 1994-05-24
DE69312870T2 (de) 1998-01-15
ITMI922674A0 (it) 1992-11-23
DK0599188T3 (da) 1998-02-02
US5567716A (en) 1996-10-22
EP0599188B1 (en) 1997-08-06
ITMI922674A1 (it) 1994-05-23
EP0599188A1 (en) 1994-06-01
GR3025074T3 (en) 1998-01-30
DE69312870D1 (de) 1997-09-11
ATE156354T1 (de) 1997-08-15
ES2106942T3 (es) 1997-11-16
JPH072725A (ja) 1995-01-06

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971128