IT1261471B - Composizione farmaceutica per somministrazione rettale nel trattamentodi cefalea e relativo metodo di preparazione ed impiego. - Google Patents
Composizione farmaceutica per somministrazione rettale nel trattamentodi cefalea e relativo metodo di preparazione ed impiego.Info
- Publication number
- IT1261471B IT1261471B ITRM930286A ITRM930286A IT1261471B IT 1261471 B IT1261471 B IT 1261471B IT RM930286 A ITRM930286 A IT RM930286A IT RM930286 A ITRM930286 A IT RM930286A IT 1261471 B IT1261471 B IT 1261471B
- Authority
- IT
- Italy
- Prior art keywords
- treatment
- pharmaceutical composition
- rectal administration
- headache
- preparation
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 206010019233 Headaches Diseases 0.000 title 1
- 231100000869 headache Toxicity 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
La invenzione si riferisce ad una composizione farmaceutica per somministrazione rettale comprendente un composto che agisce come agonista di recettore 5HTL-simile sotto forma di sua base libera o di un suo solvato fisiologicamente accettabile come ingrediente attivo, insieme con uno o più veicoli od eccipienti farmaceuticamente accettabili.Sono descritti anche metodi per la produzione di tali composizioni e per il loro impiego nel trattamento di dolore cefalico.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929209882A GB9209882D0 (en) | 1992-05-07 | 1992-05-07 | Compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM930286A0 ITRM930286A0 (it) | 1993-05-06 |
| ITRM930286A1 ITRM930286A1 (it) | 1994-11-06 |
| IT1261471B true IT1261471B (it) | 1996-05-23 |
Family
ID=10715158
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITRM930286A IT1261471B (it) | 1992-05-07 | 1993-05-06 | Composizione farmaceutica per somministrazione rettale nel trattamentodi cefalea e relativo metodo di preparazione ed impiego. |
Country Status (33)
| Country | Link |
|---|---|
| US (1) | US5705506A (it) |
| EP (1) | EP0639072B1 (it) |
| JP (1) | JPH07506570A (it) |
| KR (1) | KR100253111B1 (it) |
| AT (1) | ATE163850T1 (it) |
| AU (1) | AU670083B2 (it) |
| BE (1) | BE1007024A5 (it) |
| BG (1) | BG62120B1 (it) |
| BR (1) | BR1100108A (it) |
| CA (1) | CA2135179C (it) |
| CH (1) | CH685920A5 (it) |
| CY (1) | CY2039B1 (it) |
| CZ (1) | CZ283512B6 (it) |
| DE (1) | DE69317418T2 (it) |
| ES (1) | ES2113533T3 (it) |
| FR (1) | FR2690847B1 (it) |
| GB (2) | GB9209882D0 (it) |
| GR (1) | GR3026584T3 (it) |
| HK (1) | HK95697A (it) |
| HU (2) | HU227338B1 (it) |
| IE (1) | IE75203B1 (it) |
| IL (1) | IL105468A (it) |
| IT (1) | IT1261471B (it) |
| NO (1) | NO306700B1 (it) |
| NZ (1) | NZ252132A (it) |
| OA (1) | OA10109A (it) |
| RO (1) | RO112993B1 (it) |
| RU (1) | RU2118527C1 (it) |
| SG (1) | SG46649A1 (it) |
| TW (1) | TW231970B (it) |
| UA (1) | UA37206C2 (it) |
| WO (1) | WO1993021916A1 (it) |
| ZA (1) | ZA933178B (it) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997044062A1 (en) * | 1996-05-23 | 1997-11-27 | Alcon Laboratories, Inc. | The use of 5-ht1b/1d agonists to treat ocular pain |
| US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
| AU749623B2 (en) * | 1998-03-26 | 2002-06-27 | Astellas Pharma Inc. | Sustained release preparations |
| AU3731400A (en) * | 1999-03-05 | 2000-09-21 | Trustees Of University Technology Corporation, The | Methods and compositions useful in inhibiting apoptosis |
| AR056690A1 (es) * | 2005-10-14 | 2007-10-17 | Athersys Inc | Derivados de indol como inhibidores de indol como inhibidores del receptor 3 de histamina para el tartamiento de trastornos del sueno y cognitivos obesidad y otros trastornos de snc |
| US8653066B2 (en) | 2006-10-09 | 2014-02-18 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
| EP2240022B1 (en) | 2008-01-09 | 2016-12-28 | Charleston Laboratories, Inc. | Bilayered tablets comprising oxycodone and promethazine |
| EP2451274B1 (en) | 2009-07-08 | 2017-10-04 | Charleston Laboratories, Inc. | Pharmaceutical compositions |
| CN103402514B (zh) | 2010-10-15 | 2016-01-13 | 康特拉医药公司 | 用于治疗运动障碍的血清素受体激动剂组合物 |
| MY169068A (en) | 2012-04-18 | 2019-02-12 | Contera Pharma Aps | Orally available pharmaceutical formulation suitable for improved management of movement disorders |
| US10179109B2 (en) | 2016-03-04 | 2019-01-15 | Charleston Laboratories, Inc. | Pharmaceutical compositions comprising 5HT receptor agonist and antiemetic particulates |
| CN109689036B (zh) | 2016-07-11 | 2026-06-19 | 康特拉医药股份有限公司 | 用于治疗早晨运动不能的脉冲药物输送系统 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZW19381A1 (en) * | 1980-08-12 | 1983-03-09 | Glaxo Group Ltd | Heterocyclic compounds |
| DK157995C (da) * | 1980-08-12 | 1990-08-06 | Glaxo Group Ltd | Analogifremgangsmaade til fremstilling af indolderivater |
| GB2082175B (en) * | 1980-08-12 | 1984-05-02 | Glaxo Group Ltd | Heterocyclic compounds |
| GR79215B (it) * | 1982-06-07 | 1984-10-22 | Glaxo Group Ltd | |
| GB8332435D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
| GB2162522B (en) * | 1984-08-01 | 1988-02-24 | Glaxo Group Ltd | An indole derivative |
| GB8419575D0 (en) * | 1984-08-01 | 1984-09-05 | Glaxo Group Ltd | Chemical compounds |
| US4785016A (en) * | 1984-12-04 | 1988-11-15 | Glaxo Group Limited | Indole derivatives |
| GB8431426D0 (en) * | 1984-12-13 | 1985-01-23 | Glaxo Group Ltd | Chemical compounds |
| EP0225726B1 (en) * | 1985-11-08 | 1991-04-17 | Glaxo Group Limited | Indole derivatives |
| PH24976A (en) * | 1987-08-13 | 1990-12-26 | Glaxo Group Ltd | Indole derivatives |
| CZ288351B6 (en) * | 1990-06-07 | 2001-05-16 | Astrazeneca Ab | Nitrogenous heterocyclic compound, process of its preparation and use as well as a medicament containing thereof |
-
1992
- 1992-05-07 GB GB929209882A patent/GB9209882D0/en active Pending
-
1993
- 1993-04-20 IL IL10546893A patent/IL105468A/en not_active IP Right Cessation
- 1993-05-03 UA UA94115989A patent/UA37206C2/uk unknown
- 1993-05-03 DE DE69317418T patent/DE69317418T2/de not_active Expired - Lifetime
- 1993-05-03 JP JP5518928A patent/JPH07506570A/ja active Pending
- 1993-05-03 US US08/331,485 patent/US5705506A/en not_active Expired - Fee Related
- 1993-05-03 AU AU40640/93A patent/AU670083B2/en not_active Ceased
- 1993-05-03 AT AT93909884T patent/ATE163850T1/de active
- 1993-05-03 NZ NZ252132A patent/NZ252132A/en not_active IP Right Cessation
- 1993-05-03 RU RU94046069/14A patent/RU2118527C1/ru not_active IP Right Cessation
- 1993-05-03 CA CA002135179A patent/CA2135179C/en not_active Expired - Fee Related
- 1993-05-03 CZ CZ942723A patent/CZ283512B6/cs not_active IP Right Cessation
- 1993-05-03 ES ES93909884T patent/ES2113533T3/es not_active Expired - Lifetime
- 1993-05-03 WO PCT/EP1993/001077 patent/WO1993021916A1/en not_active Ceased
- 1993-05-03 HU HU9403188A patent/HU227338B1/hu unknown
- 1993-05-03 EP EP93909884A patent/EP0639072B1/en not_active Expired - Lifetime
- 1993-05-03 RO RO94-01790A patent/RO112993B1/ro unknown
- 1993-05-05 SG SG1996007136A patent/SG46649A1/en unknown
- 1993-05-05 GB GB9309209A patent/GB2266665B/en not_active Expired - Lifetime
- 1993-05-06 BE BE9300467A patent/BE1007024A5/fr not_active IP Right Cessation
- 1993-05-06 IE IE930339A patent/IE75203B1/en not_active IP Right Cessation
- 1993-05-06 CH CH139793A patent/CH685920A5/fr not_active IP Right Cessation
- 1993-05-06 ZA ZA933178A patent/ZA933178B/xx unknown
- 1993-05-06 FR FR9305432A patent/FR2690847B1/fr not_active Expired - Lifetime
- 1993-05-06 IT ITRM930286A patent/IT1261471B/it active IP Right Grant
- 1993-05-12 TW TW082103742A patent/TW231970B/zh active
-
1994
- 1994-11-04 OA OA60578A patent/OA10109A/en unknown
- 1994-11-04 NO NO944214A patent/NO306700B1/no not_active IP Right Cessation
- 1994-11-05 KR KR1019940703950A patent/KR100253111B1/ko not_active Expired - Fee Related
- 1994-11-07 BG BG99167A patent/BG62120B1/bg unknown
-
1995
- 1995-06-29 HU HU95P/P00531P patent/HU211638A9/hu unknown
-
1996
- 1996-12-24 BR BR1100108-9A patent/BR1100108A/pt active IP Right Grant
-
1997
- 1997-06-26 HK HK95697A patent/HK95697A/xx not_active IP Right Cessation
-
1998
- 1998-04-10 GR GR980400773T patent/GR3026584T3/el unknown
- 1998-04-30 CY CY9802039A patent/CY2039B1/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IT1282352B1 (it) | Composizione farmaceutica, in particolare essiccata mediante congelamento, per somministrazione orale di ondansetron e metodo per | |
| CY1105931T1 (el) | Χρηση ενος αγωνιστη/ανταγωνιστη οιστρογονου για την αντιμετωπιση γυναικειας σεξουαλικης δυσλειτουργιας | |
| PL372809A1 (en) | Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof | |
| ITFI930247A1 (it) | Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche. | |
| EE04911B1 (et) | Ühend ja farmatseutiline kompositsioon proteaasi inhibiitoritena, nende kasutamine ning meetod selle ühendi valmistamiseks | |
| CL2009001682A1 (es) | Composición farmacéutica espontáneamente dispersable para administración oral que comprende n-benzoil-estaurosporina; método para incrementar los niveles de biodisponibilidad. (divisional de la solocitud 333-00). | |
| BR9808429A (pt) | Composição farmacêutica e processo para a sua preparação. | |
| RU95106649A (ru) | Производные бензимидазола в качестве непептидильных антагонистов рецепторов тахикинина, способ получения, фармацевтическая композиция | |
| FI973518A7 (fi) | Piperidinoalkanoliyhdistettä tai sen farmaseuttisesti hyväksyttävää suolaa sisltävä farmaseuttinen koostumus kiinteässä yksikköannosmuodossa | |
| ATE216590T1 (de) | Arzneimittelformulierungen für il-12 | |
| CO5251419A1 (es) | Composiciones nanoparticuladas de eplerenona | |
| ID26128A (id) | Senyawa-senyawa aminotetralin tersubstitusi-n sebagai ligan-ligan untuk reseptor neupeptida y y5 yang bermanfaat dalam pengobatan obesitas dan gangguan-gangguan lain | |
| TR199801861T2 (xx) | Farmas�tik olarak yararl� bile�imler. | |
| SE0102036D0 (sv) | Pharmaceutical formulation for the efficient administration of apomorphine, 6aR- (-) -N- Propyl- norapomorphine and their derivatives and pro-drugs thereof | |
| EA200301223A1 (ru) | Лекарственные формы окскарбазепина | |
| BR0209283A (pt) | Método para a fabricação de uma composição farmacêutica de baixa dosagem tendo distribuição e potência de droga uniforme | |
| HUP0103203A2 (hu) | Azaadamantánszármazékok és ezeket tartalmazó gyógyszerkészítmények | |
| DK1057828T3 (da) | Orale trovafloxacin-suspensioner | |
| CA2135179A1 (en) | Pharmaceutical Compositions of Alkylsulphonamides 5HT1 Agonists for Rectal Administration | |
| ES2062137T3 (es) | Utilizacion de 5'-deoxi-5'-metil-tioadenosina, s-adenosilmetionina y sus sales para la preparacion de composiciones farmaceuticas reductoras de seborrea. | |
| ATE319715T1 (de) | Antikonvulsive pseudofructopyranose sulfamate | |
| PL350568A1 (en) | N-(2-phenyl-4-aminobutyl)-1-naphtamides as antagonists of neurokinin 1 receptors | |
| RU94040150A (ru) | Стабильная лиофилизированная композиция тиотепа, способ ее получения | |
| IT1256623B (it) | Antagonisti delle tachichinine, procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche | |
| AR035006A1 (es) | Derivado de naftiridin-dibenzo[a,d]ciclohepteno-10-acetico, composicion farmaceutica, y el uso de dicho derivado para la fabricacion de un medicamento. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970530 |