IT1264020B - Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi - Google Patents

Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi

Info

Publication number
IT1264020B
IT1264020B ITMI930136A ITMI930136A IT1264020B IT 1264020 B IT1264020 B IT 1264020B IT MI930136 A ITMI930136 A IT MI930136A IT MI930136 A ITMI930136 A IT MI930136A IT 1264020 B IT1264020 B IT 1264020B
Authority
IT
Italy
Prior art keywords
liquids
suspension
microgranules
preparation
procedure
Prior art date
Application number
ITMI930136A
Other languages
English (en)
Inventor
Giancarlo Santus
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11364782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1264020(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Priority to ITMI930136A priority Critical patent/IT1264020B/it
Publication of ITMI930136A0 publication Critical patent/ITMI930136A0/it
Priority to SG1996004318A priority patent/SG47772A1/en
Priority to DK94101105T priority patent/DK0608850T3/da
Priority to EP94101105A priority patent/EP0608850B1/en
Priority to DE69412295T priority patent/DE69412295T2/de
Priority to AT94101105T priority patent/ATE169497T1/de
Priority to ES94101105T priority patent/ES2122050T3/es
Priority to JP02605594A priority patent/JP3184912B2/ja
Priority to US08/188,193 priority patent/US5460828A/en
Publication of ITMI930136A1 publication Critical patent/ITMI930136A1/it
Publication of IT1264020B publication Critical patent/IT1264020B/it
Application granted granted Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Glanulating (AREA)

Abstract

Oggetto dell'invenzione è un procedimento per la preparazione di microgranuli da utilizzare in composizioni farmaceutiche liquide a rilascio controllato. Il procedimento, operando con impastatori veloci entro ben definiti intervalli di parametri critici, consente l'ottenimento di microgranuli aventi distribuzione granulometrica, densità, superficie e forma tali da renderli particolarmente adatti alla ricopertura filmogena e alla sospensione in liquidi.
ITMI930136A 1993-01-28 1993-01-28 Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi IT1264020B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ITMI930136A IT1264020B (it) 1993-01-28 1993-01-28 Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi
ES94101105T ES2122050T3 (es) 1993-01-28 1994-01-26 Procedimiento de preparacion de microgranulos adecuados para la suspencion despues del recubrimiento en composiciones farmaceuticas liquidas.
EP94101105A EP0608850B1 (en) 1993-01-28 1994-01-26 Process for the preparation of microgranules suitable for suspension after coating in pharmaceutical liquid compositions
DK94101105T DK0608850T3 (da) 1993-01-28 1994-01-26 Fremgangsmåde til fremstilling af mikrogranulater, som efter belægninger egnede til opslæmning i flydende farmaceutiske præ
SG1996004318A SG47772A1 (en) 1993-01-28 1994-01-26 Process for the preparation of microgranules suitable for suspension after coating in pharmaceutical liquid compositions
DE69412295T DE69412295T2 (de) 1993-01-28 1994-01-26 Verfahren zur Herstellung von Mikrogranulaten, die nach Umhüllung zur Suspendierung in flüssigen Pharmazeutika geeignet sind
AT94101105T ATE169497T1 (de) 1993-01-28 1994-01-26 Verfahren zur herstellung von mikrogranulaten, die nach umhüllung zur suspendierung in flüssigen pharmazeutika geeignet sind
JP02605594A JP3184912B2 (ja) 1993-01-28 1994-01-27 液体への懸濁に適した微粒剤の調製方法
US08/188,193 US5460828A (en) 1993-01-28 1994-01-28 Process for the preparation of microgranules suitable for suspension in fluids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI930136A IT1264020B (it) 1993-01-28 1993-01-28 Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi

Publications (3)

Publication Number Publication Date
ITMI930136A0 ITMI930136A0 (it) 1993-01-28
ITMI930136A1 ITMI930136A1 (it) 1994-07-28
IT1264020B true IT1264020B (it) 1996-09-09

Family

ID=11364782

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI930136A IT1264020B (it) 1993-01-28 1993-01-28 Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi

Country Status (9)

Country Link
US (1) US5460828A (it)
EP (1) EP0608850B1 (it)
JP (1) JP3184912B2 (it)
AT (1) ATE169497T1 (it)
DE (1) DE69412295T2 (it)
DK (1) DK0608850T3 (it)
ES (1) ES2122050T3 (it)
IT (1) IT1264020B (it)
SG (1) SG47772A1 (it)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958458A (en) * 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
IT1270594B (it) * 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
GB9518465D0 (en) * 1995-09-09 1995-11-08 Smithkline Beecham Seiyaku Kk Pharmaceuticals
US6214386B1 (en) 1995-11-22 2001-04-10 Recordati, S.A. Prompt-release oral pharmaceutical compositions for extemporaneous suspensions
GB9710767D0 (en) * 1996-06-26 1997-07-23 On Ninh Analgesic and anti-inflamatory compositions comprising domperidone and methods of using same
FR2758459B1 (fr) * 1997-01-17 1999-05-07 Pharma Pass Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation
US6184220B1 (en) * 1998-03-27 2001-02-06 Boehringer Ingelheim Pharma Kg Oral suspension of pharmaceutical substance
GB9816899D0 (en) 1998-08-05 1998-09-30 Boots Co Plc Therapeutic agents
JP2000128774A (ja) * 1998-10-26 2000-05-09 Tanabe Seiyaku Co Ltd 薬物を含有する球形微粒子の製法
AU2860500A (en) * 1999-01-29 2000-08-18 Meri Charmyne Russell Treatement of colic and gut spasm in horses and other vertebrates
KR100889069B1 (ko) 1999-10-29 2009-03-17 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
US6730691B1 (en) 2000-02-10 2004-05-04 Miles A. Galin Uses of alpha adrenergic blocking agents
AU2738302A (en) 2000-10-30 2002-05-15 Euro Celtique Sa Controlled release hydrocodone formulations
US20020119196A1 (en) * 2000-12-21 2002-08-29 Narendra Parikh Texture masked particles containing an active ingredient
JP4848101B2 (ja) * 2001-08-17 2011-12-28 株式会社フジモト・コーポレーション 徐放性マイクロペレット
US6723348B2 (en) * 2001-11-16 2004-04-20 Ethypharm Orodispersible tablets containing fexofenadine
KR20040098023A (ko) * 2002-03-26 2004-11-18 테바 파마슈티컬 인더스트리즈 리미티드 약물 미세입자
US20040131771A1 (en) * 2002-11-04 2004-07-08 Poul Egon Bertelsen Coating of particulate material with organic based coating composition for the preparation of drug delivery systems
US8062664B2 (en) * 2003-11-12 2011-11-22 Abbott Laboratories Process for preparing formulations of lipid-regulating drugs
US20050131079A1 (en) * 2003-12-10 2005-06-16 Pujara Chetan P. Cefdinir oral suspension
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
AR045841A1 (es) * 2004-09-28 2005-11-16 Richmond Sa Com Ind Y Financie Una composicion farmaceutica solida que comprende al tiazolil metil ester del acido [5s-(5r*, 8r*, 10r*,11r*)] -10- hidroxi-2- metil-5-(1-metiletil)-1-[2-(1-metiletil)-4-tiazolil]-3,6-dioxo-8,11-bis(fenilmetil)-2,4,7,12- tetraazatridecan-13-oico y un procedimiento para prepararla.
US20080069891A1 (en) 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
US8445018B2 (en) 2006-09-15 2013-05-21 Cima Labs Inc. Abuse resistant drug formulation
WO2008103245A2 (en) * 2007-02-23 2008-08-28 Glatt Air Techniques, Inc. Method of determining the weight of the coating to be applied to form a controlled release dosage form
US8445545B2 (en) * 2008-05-07 2013-05-21 Nicholas DeSica Pharmaceutical composition, method of preparation and methods of treating aches/pains
CA2798702A1 (en) 2010-05-11 2011-11-17 Cima Labs Inc. Alcoholresistant metoprolol-containing extended-release oral dosage forms
US20180104197A9 (en) 2014-05-01 2018-04-19 Sun Pharmaceutical Industries Limited Extended release liquid compositions of metformin
US10258583B2 (en) 2014-05-01 2019-04-16 Sun Pharmaceutical Industries Limited Extended release liquid compositions of guanfacine
US9962336B2 (en) * 2014-05-01 2018-05-08 Sun Pharmaceutical Industries Limited Extended release suspension compositions
MX2016014320A (es) 2014-05-01 2017-05-23 Sun Pharmaceutical Ind Ltd Composiciones de suspension de liberacion prolongada.
BR112017001968A2 (pt) 2014-07-30 2017-11-21 Sun Pharmaceutical Ind Ltd embalagem de duas câmaras para uma composição farmacêutica líquida oral de múltiplas doses
KR20170052626A (ko) * 2014-09-05 2017-05-12 심바이오믹스 세러퓨틱스 엘엘씨 세균질증 치료에 사용하기 위한 세크니다졸
US10369078B2 (en) 2016-05-02 2019-08-06 Sun Pharmaceutical Industries Limited Dual-chamber pack for pharmaceutical compositions
US10238803B2 (en) 2016-05-02 2019-03-26 Sun Pharmaceutical Industries Limited Drug delivery device for pharmaceutical compositions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5854852B2 (ja) * 1975-03-17 1983-12-07 武田薬品工業株式会社 サイリユウザイノセイゾウホウ
CA1114683A (en) * 1978-01-03 1981-12-22 Robert J. Boyle Fire retardant treatment of fire unstable materials and products
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
JPS63240934A (ja) * 1987-03-28 1988-10-06 Taisho Pharmaceut Co Ltd 薬物の造粒法
NL193682C (nl) * 1987-05-14 2000-07-04 Glaxo Group Ltd Beklede cefuroximaxetilsamenstelling.
IT1215726B (it) * 1988-01-18 1990-02-22 Alfa Wassermann Spa Formulazioni galeniche a cessione programmata.
US5296236A (en) * 1988-09-16 1994-03-22 Recordati S.A., Chemical And Pharmaceutical Company Controlled release therapeutic system for a liquid pharmaceutical formulations
CA1331713C (en) * 1988-12-29 1994-08-30 Hitoshi Iijima Granular composition for ruminant

Also Published As

Publication number Publication date
ITMI930136A0 (it) 1993-01-28
SG47772A1 (en) 1998-04-17
JP3184912B2 (ja) 2001-07-09
DE69412295D1 (de) 1998-09-17
EP0608850A1 (en) 1994-08-03
DE69412295T2 (de) 1999-02-11
ITMI930136A1 (it) 1994-07-28
US5460828A (en) 1995-10-24
ES2122050T3 (es) 1998-12-16
EP0608850B1 (en) 1998-08-12
ATE169497T1 (de) 1998-08-15
JPH06319786A (ja) 1994-11-22
DK0608850T3 (da) 1999-05-17

Similar Documents

Publication Publication Date Title
IT1264020B (it) Procedimento per la preparazione di microgranuli idonei alla sospensione in liquidi
TNSN94064A1 (fr) Procede et appareil de fabrication d'articles de confiserie glacee
JPS57120518A (en) Preparation of microcapsule
PT797987E (pt) Preparacao granular de libertacao controlada e processo para a sua preparacao
IL67939A0 (en) Production of pulverulent mixture of lipidic constituents and hydrophobic constituents,hydrated lipidic lamellar phases obtained therefrom and pharmaceutical and cosmetic composition comprising such phases
HUT52941A (en) Process for producing hydrosols of pharmaceutically active materials and pharmaceutical compositions comprising such hydrosols
BG98933A (en) Cooled and atomized nabumetone
IL88016A0 (en) Liquid ibuprofen compositions and methods of making them
DE68916048D1 (de) Verfahren zur Herstellung von monodispersen Polymerteilchen mit erhöhter Teilchengrösse.
ATE17740T1 (de) Katalysatoren zur polymerisation und copolymerisation von propylen, sowie polymerisationsverfahren, die solche katalysatoren verwenden.
AR010508A1 (es) Proceso para fabricar una composicion detergente que no se realiza en torre
DE69800279D1 (de) Kontinuierliches Verfahren zur Herstellung von Pulverbeschichtungszusammensetzungen
EP0596138A4 (en) FINE BOWL-SHAPED PARTICLE AND PROCESS FOR PRODUCING THE SAME.
DE69130322D1 (de) Feines, plättchenförmiges pulver, herstellungsverfahren, und kosmetisches produkt
MX9300939A (es) Metodo para preparar una composicion comestible, composiciones que la contienen y metodo para prepararlas.
EP0197206A3 (en) Article for the presentation of a pasty cosmetic product and the related production process
AU567232B2 (en) Preparation of polyamide coating powders
EP0857747A4 (en) GRANULAR POWDER COMPRISING POLYTETRAFLUOROETHYLENE AND METHOD OF MANUFACTURE
Zhang et al. Fine structures of chromospheric magnetic field and material flow in a solar active region
BR8700124A (pt) Processo para a fabricacao de um produto antiperspirante do tipo de locao
JPS6440565A (en) Composite powder and production thereof
DE69402427D1 (de) Neuer nahrungsmittelüberzug
JPS543953A (en) Vibrating type particle shape controlling apparatus
JPS6427642A (en) Silver catalyst
Sjoberg Powder Casting and Metal Injection Moulding

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960130