IT1269301B - Procedimento per la conversione della cefalosporina c in acido glutaril - 7 amminocefalosporanico - Google Patents

Procedimento per la conversione della cefalosporina c in acido glutaril - 7 amminocefalosporanico

Info

Publication number
IT1269301B
IT1269301B ITMI940418A ITMI940418A IT1269301B IT 1269301 B IT1269301 B IT 1269301B IT MI940418 A ITMI940418 A IT MI940418A IT MI940418 A ITMI940418 A IT MI940418A IT 1269301 B IT1269301 B IT 1269301B
Authority
IT
Italy
Prior art keywords
cephalosporin
glutaryl
acid
present
glutaril
Prior art date
Application number
ITMI940418A
Other languages
English (en)
Inventor
Kenji Matsuyama
Satoshi Soga
Original Assignee
Asahi Chemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Ind filed Critical Asahi Chemical Ind
Publication of ITMI940418A0 publication Critical patent/ITMI940418A0/it
Publication of ITMI940418A1 publication Critical patent/ITMI940418A1/it
Application granted granted Critical
Publication of IT1269301B publication Critical patent/IT1269301B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

La presente invenzione riguarda un migliorato procedimento di ossidazione enzimatica per convertire la cefalosporina C in acido glutaril-7-amminocefalosporanico (glutaril-7-ACA) che prevede l'uso di una miscela contenente D-amminoacido-ossidasi, la cui attività esterasica è del 5% o meno dell'attività della DAO.Secondo il procedimento della presente invenzione, la resa eccellente del glutaril-7-ACA può essere ottenuta in termini di qualità.Inoltre, il procedimento della presente invenzione prevede tappe semplici e sicure ed è perciò applicabile su scala industriale.
ITMI940418A 1993-03-08 1994-03-08 Procedimento per la conversione della cefalosporina c in acido glutaril - 7 amminocefalosporanico IT1269301B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7072793 1993-03-08

Publications (3)

Publication Number Publication Date
ITMI940418A0 ITMI940418A0 (it) 1994-03-08
ITMI940418A1 ITMI940418A1 (it) 1995-09-08
IT1269301B true IT1269301B (it) 1997-03-26

Family

ID=13439867

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI940418A IT1269301B (it) 1993-03-08 1994-03-08 Procedimento per la conversione della cefalosporina c in acido glutaril - 7 amminocefalosporanico

Country Status (7)

Country Link
JP (1) JPH06315396A (it)
AT (1) AT401269B (it)
DE (1) DE4407699C2 (it)
ES (1) ES2097080B1 (it)
FR (1) FR2702493B1 (it)
GB (1) GB2275925B (it)
IT (1) IT1269301B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6465227B1 (en) 1997-09-09 2002-10-15 Biochemie Gesellschaft M.B.H. Spherical particles containing microorganism cells having enzyme activity
JP7101671B2 (ja) 2019-01-15 2022-07-15 ザ プロクター アンド ギャンブル カンパニー 可撓性かつ溶解性の固体シート物品
KR20230110833A (ko) 2019-01-15 2023-07-25 더 프록터 앤드 갬블 캄파니 개구 또는 구멍을 갖는 다층 용해성 고체 물품
WO2020147010A1 (en) 2019-01-15 2020-07-23 The Procter & Gamble Company Multilayer dissolvable solid article with specific aspect ratio

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1272769A (en) * 1968-08-02 1972-05-03 Glaxo Lab Ltd Improvements in or relating to cephalosporin derivatives
GB1385685A (en) * 1971-04-21 1975-02-26 Glaxo Lab Ltd Cephalosporin derivatives
EP0465600B1 (en) * 1989-04-04 1995-06-07 Biopure Corporation Enzymatic production of 7-amino cephalosporanic acid
EP0601996A1 (en) * 1989-07-19 1994-06-15 Eli Lilly And Company Improved enzymatic oxidation of ceph C to glutaryl-7-amino-cephalosporanic acid
DE4028119C1 (it) * 1990-09-05 1991-12-05 Hoechst Ag, 6230 Frankfurt, De
IT1252308B (it) * 1990-12-21 1995-06-08 Antibioticos Spa Procedimento enzimatico per la produzione di acido 7- amminocefalosporanico e derivati
CA2100987C (en) * 1992-07-27 1999-06-15 Kaoru Furuya A transformant capable of producing d-amino acid oxidase

Also Published As

Publication number Publication date
ITMI940418A0 (it) 1994-03-08
GB2275925A (en) 1994-09-14
AT401269B (de) 1996-07-25
ATA47694A (de) 1995-12-15
FR2702493A1 (fr) 1994-09-16
ES2097080B1 (es) 1997-11-16
FR2702493B1 (fr) 1996-02-02
GB9404103D0 (en) 1994-04-20
JPH06315396A (ja) 1994-11-15
ITMI940418A1 (it) 1995-09-08
DE4407699C2 (de) 2003-12-18
GB2275925B (en) 1996-08-14
ES2097080A1 (es) 1997-03-16
DE4407699A1 (de) 1994-09-15

Similar Documents

Publication Publication Date Title
ES2106615T3 (es) Procedimiento para la preparacion de clavulanato de potasio.
KR890700658A (ko) 아스타크산틴-생산 효모 세포, 그의 제조방법 및 용도
EP0464325A3 (en) Process for the preparation of l-ornithine salts
SG46729A1 (en) Novel microorganisms their use and process for the production of l-amimo acids
GB9409135D0 (en) Gamma-pyrone-acetic acid as an inhibitor of interleukin-1B converting enzyme
ATE123533T1 (de) Enzymatisches verfahren zur herstellung von 7- aminocephalosporansäure.
TW274565B (it)
CA2100987A1 (en) A transformant capable of producing d-amino acid oxidase
GR3018713T3 (en) Process for the continuous transformation of cephalosporin derivatives in glutaryl-7-amino-cephalosporin derivatives
WO1993004181A1 (fr) Procede pour la production de 4-hydroxy-l-proline
HU212587B (en) Method for deactivating esterase/catalase enzyme in triginopsis variabilis and process for the enzymatic oxydation of cephalosporino to glutaryl-7-aminocephalosporanic acid
CA2018562A1 (en) Process for the enzymatic cleavage of vinyl 2-aryl-propionates
AU1329895A (en) Metallic implant and process for treating a metallic implant
ES2097080A1 (es) Procedimiento para la conversion de cefalosporina c en acido glutaril-7-aminocefalosporanico.
MX9705917A (es) Procedimiento para la recuperacion de cefalexina.
NZ326147A (en) Process for the preparation of gluconic acid and gluconic acid produced thereby
DE3574018D1 (en) Process for the preparation of n1-methyl-10alpha-methoxylumilysergol and esters thereof, and intermediates for their preparation
AU5684099A (en) Process for preparing piperazic acid and its conversion to n-acylated bicyclic rings containing n,n-linkages useful as intermediates for caspase inhibitors
ES8407094A1 (es) Un procedimiento de produccion de glucosa deshidrogenasa.
ES8200400A1 (es) Un procedimiento para obtener acido d(-)-beta-hidroxiisobu- tirico
IN183010B (it)
EP0521305A3 (en) Stabilized metal ion activated l-arginase (l-arginine amidinohydrolase; e.c. 3.5.3.1.)
IT1256043B (it) Ceppo mutante di yarrowia lipolytica e procedimento per la produzione di acido citrico
TW243453B (en) Cloning and characterization of a cardiac adenylyl cyclase
JPS6447374A (en) Novel microorganism

Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19961021