IT1285387B1 - Dispositivo e procedimento per la somministrazione transdermica mediante elettrotrasporto di fentanil e sufentanil. - Google Patents

Dispositivo e procedimento per la somministrazione transdermica mediante elettrotrasporto di fentanil e sufentanil.

Info

Publication number
IT1285387B1
IT1285387B1 IT96TO000477A ITTO960477A IT1285387B1 IT 1285387 B1 IT1285387 B1 IT 1285387B1 IT 96TO000477 A IT96TO000477 A IT 96TO000477A IT TO960477 A ITTO960477 A IT TO960477A IT 1285387 B1 IT1285387 B1 IT 1285387B1
Authority
IT
Italy
Prior art keywords
electrotransportation
fentanil
sufentanil
procedure
transdermal administration
Prior art date
Application number
IT96TO000477A
Other languages
English (en)
Inventor
Joseph B Phipps
Mary Southam
Keith J Bernstein
Henk Noorduin
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23848034&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1285387(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alza Corp filed Critical Alza Corp
Publication of ITTO960477A0 publication Critical patent/ITTO960477A0/it
Publication of ITTO960477A1 publication Critical patent/ITTO960477A1/it
Application granted granted Critical
Publication of IT1285387B1 publication Critical patent/IT1285387B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Electrotherapy Devices (AREA)
IT96TO000477A 1995-06-05 1996-06-03 Dispositivo e procedimento per la somministrazione transdermica mediante elettrotrasporto di fentanil e sufentanil. IT1285387B1 (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/465,492 US6881208B1 (en) 1995-06-05 1995-06-05 Method and device for transdermal electrotransport delivery of fentanyl and sufentanil

Publications (3)

Publication Number Publication Date
ITTO960477A0 ITTO960477A0 (it) 1996-06-03
ITTO960477A1 ITTO960477A1 (it) 1997-12-03
IT1285387B1 true IT1285387B1 (it) 1998-06-03

Family

ID=23848034

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96TO000477A IT1285387B1 (it) 1995-06-05 1996-06-03 Dispositivo e procedimento per la somministrazione transdermica mediante elettrotrasporto di fentanil e sufentanil.

Country Status (20)

Country Link
US (3) US6881208B1 (it)
JP (3) JPH11506684A (it)
KR (1) KR100431364B1 (it)
CN (1) CN1118308C (it)
AT (1) AT409088B (it)
AU (1) AU695465B2 (it)
BE (1) BE1009505A3 (it)
BR (1) BR9609137B1 (it)
CA (2) CA2219736C (it)
CH (1) CH690751A5 (it)
DE (1) DE19681420B4 (it)
FR (1) FR2736837B1 (it)
GB (1) GB2317115B (it)
GR (1) GR1002982B (it)
IE (1) IE960374A1 (it)
IT (1) IT1285387B1 (it)
NL (1) NL1003274C2 (it)
SE (1) SE521220C2 (it)
WO (1) WO1996039224A1 (it)
ZA (1) ZA964658B (it)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6881208B1 (en) * 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
CN1189224C (zh) 1998-01-28 2005-02-16 阿尔扎有限公司 初始电阻较低的电传输电极组合件
US6858018B1 (en) 1998-09-28 2005-02-22 Vyteris, Inc. Iontophoretic devices
AU766913B2 (en) 1998-11-02 2003-10-23 Alza Corporation Electrotransport device including a compatible antimicrobial agent
US6541021B1 (en) * 1999-03-18 2003-04-01 Durect Corporation Devices and methods for pain management
US6496727B1 (en) * 2000-05-31 2002-12-17 Becton, Dickinson And Company Medicament-loaded transdermal reservoir and method for its formation
JP4898073B2 (ja) 2000-07-31 2012-03-14 ニュコメデ ダンマルク アンパーツセルスカブ 鼻内投与用フェンタニル組成物
EP1317306B1 (en) * 2000-09-11 2005-04-20 Alza Corporation Transdermal electrotransport device and method for manufacturing same
DE60227938D1 (de) 2001-04-04 2008-09-11 Alza Corp Transdermales verabreichungsgerät mittels elektrotransport mit einer kompatiblen antimikrobiellen reservoir-lösung
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US6975902B2 (en) * 2002-06-28 2005-12-13 Alza Corporation Reservoir and a series of related reservoirs for use in an electrotransport drug delivery device and devices comprised thereof
GB0300531D0 (en) 2003-01-10 2003-02-12 West Pharm Serv Drug Res Ltd Pharmaceutical compositions
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8357114B2 (en) * 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
US9066847B2 (en) 2007-01-05 2015-06-30 Aceirx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8753308B2 (en) 2006-01-06 2014-06-17 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US9289583B2 (en) 2006-01-06 2016-03-22 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8252328B2 (en) 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US20070299687A1 (en) * 2006-06-23 2007-12-27 Pamela Palmer Inpatient system for patient-controlled delivery of oral transmucosal medications dosed as needed
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
US20080004671A1 (en) * 2006-06-28 2008-01-03 Alza Corporation Vagus nerve stimulation via orally delivered apparatus
WO2009002337A1 (en) * 2006-06-28 2008-12-31 Alza Corporation Methods and devices for transdermal electrotransport delivery of lofentanil and carfentanil
KR100730582B1 (ko) * 2006-11-20 2007-06-20 아람휴비스(주) 이온토포레시스 장치
US20080154230A1 (en) * 2006-12-20 2008-06-26 Janardhanan Anand Subramony Anode for electrotransport of cationic drug
US20090105634A1 (en) * 2007-10-17 2009-04-23 Alza Corporation Anodic Reservoir for Electrotransport of Cationic Drug
US20090105632A1 (en) * 2007-10-18 2009-04-23 Padmanabhan Rama V Electrotransport Of Lisuride
WO2009123970A2 (en) * 2008-04-01 2009-10-08 Alza Corporation Electrotransport fentanyl delivery device with consistent delivery
WO2009158032A1 (en) * 2008-06-25 2009-12-30 Fe2, Inc. Patches and methods for the transdermal delivery of a therapeutically effective amount of iron
US20100004583A1 (en) * 2008-07-01 2010-01-07 Alza Corporation Hydrophobic Circuit Board Coating of Electrotransport Drug Delivery Devices
ES2481668T3 (es) * 2008-09-02 2014-07-31 Teikoku Pharma Usa, Inc. Diseño de electrodo de sacrificio y especie de administración adecuada para periodos prolongados de aplicación de iontoforesis
US8945592B2 (en) 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
CA2944660A1 (en) 2008-12-30 2010-07-08 Teva Pharmaceuticals International Gmbh Electronic control of drug delivery system
US9008765B2 (en) 2009-02-12 2015-04-14 Incube Labs, Llc System and method for biphasic transdermal iontophoretic delivery of therapeutic agents for the control of addictive cravings
US8961492B2 (en) 2009-02-12 2015-02-24 Incube Labs, Llc System and method for controlling the iontophoretic delivery of therapeutic agents based on user inhalation
US8190252B2 (en) 2009-02-12 2012-05-29 Incube Labs, Llc Iontophoretic system for transdermal delivery of active agents for therapeutic and medicinal purposes
WO2010107761A1 (en) 2009-03-18 2010-09-23 Acelrx Pharmaceuticals, Inc. Improved storage and dispensing devices for administration of oral transmucosal dosage forms
US8821945B2 (en) 2009-04-25 2014-09-02 Fe3 Medical, Inc. Method for transdermal iontophoretic delivery of chelated agents
CN102458567B (zh) * 2009-04-25 2015-04-08 因卡伯实验室有限责任公司 螯合药剂的透皮离子电渗递送方法
WO2011044175A2 (en) 2009-10-06 2011-04-14 Incube Labs, Llc Patch and patch assembly for iontophoretic transdermal delivery of active agents for therapeutic and medicinal purposes
US8685038B2 (en) 2009-12-07 2014-04-01 Incube Labs, Llc Iontophoretic apparatus and method for marking of the skin
US8986279B2 (en) 2010-02-10 2015-03-24 Incube Labs, Llc Methods and architecture for power optimization of iontophoretic transdermal drug delivery
JP5927506B2 (ja) 2010-04-13 2016-06-01 レルマダ セラピューティクス、インク． １−メチル−２’，６’−ピペコロキシリダイドの皮膚医薬組成物および使用方法
CN103228318B (zh) 2010-11-23 2016-03-23 泰华制药国际有限公司 使用者激活的自包含共封装的离子透入给药系统
CN106955415B (zh) * 2011-03-24 2019-06-18 因卡伯实验室有限责任公司 用于治疗剂的两阶段经皮离子电渗递送的系统及方法
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
KR102196741B1 (ko) 2012-04-17 2020-12-30 퍼듀 퍼머 엘피 오피오이드-유도 유해 약역학 반응을 치료하기 위한 시스템 및 방법
BR112017013311B1 (pt) 2014-12-23 2022-05-31 Acelrx Pharmaceuticals, Inc Aparelho para a dispensação de formas de dosagem via oral e transmucosal
EP4691545A1 (en) 2023-03-28 2026-02-11 Kikkoman Corporation Transdermal current-carrying patch

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141359A (en) 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4856188A (en) 1984-10-12 1989-08-15 Drug Delivery Systems Inc. Method for making disposable and/or replenishable transdermal drug applicators
US5224928A (en) 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
US5135479A (en) 1983-08-18 1992-08-04 Drug Delivery Systems, Inc. Programmable control and mounting system for transdermal drug applicator
US4588580B2 (en) 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
US5135477A (en) 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
US4752285B1 (en) 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US5080646A (en) 1988-10-03 1992-01-14 Alza Corporation Membrane for electrotransport transdermal drug delivery
US4931046A (en) * 1987-05-15 1990-06-05 Newman Martin H Iontophoresis drug delivery system
US5006108A (en) 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US5320597A (en) 1991-02-08 1994-06-14 Becton, Dickinson And Company Device and method for renewing electrodes during iontophoresis
US5232448A (en) 1989-12-05 1993-08-03 Prime Medical Products Patient-controlled analgesia device
US5167616A (en) 1989-12-14 1992-12-01 Alza Corporation Iontophoretic delivery method
IT1244030B (it) 1989-12-21 1994-06-28 Elan Corp Plc Dispostitivo in due parti per la somministrazione controllata di un ingrediente
US5047007A (en) 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
DK0521988T3 (da) * 1990-03-30 1996-04-29 Alza Corp Anordning til iontoforetisk lægemiddeltilførsel
US5125894A (en) * 1990-03-30 1992-06-30 Alza Corporation Method and apparatus for controlled environment electrotransport
US5224927A (en) 1990-11-01 1993-07-06 Robert Tapper Iontophoretic treatment system
US5254081A (en) 1991-02-01 1993-10-19 Empi, Inc. Multiple site drug iontophoresis electronic device and method
US5464387A (en) * 1991-07-24 1995-11-07 Alza Corporation Transdermal delivery device
US5203768A (en) 1991-07-24 1993-04-20 Alza Corporation Transdermal delivery device
US5246418A (en) 1991-12-17 1993-09-21 Becton Dickinson And Company Iontophresis system having features for reducing skin irritation
FR2687321B1 (fr) * 1992-02-14 1999-04-16 Elf Aquitaine Dispositif d'ionophorese pour l'administration transcutanee d'une quantite totale donnee d'un principe actif a un sujet.
US5298017A (en) 1992-12-29 1994-03-29 Alza Corporation Layered electrotransport drug delivery system
US7027859B1 (en) * 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US5879322A (en) * 1995-03-24 1999-03-09 Alza Corporation Self-contained transdermal drug delivery device
US6216033B1 (en) * 1996-05-22 2001-04-10 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6881208B1 (en) * 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil

Also Published As

Publication number Publication date
FR2736837B1 (fr) 1998-07-24
NL1003274A1 (nl) 1996-12-06
CA2613061C (en) 2010-02-09
SE521220C2 (sv) 2003-10-14
JP4070779B2 (ja) 2008-04-02
AU695465B2 (en) 1998-08-13
DE19681420T1 (de) 1998-05-20
DE19681420B4 (de) 2009-05-28
BE1009505A3 (fr) 1997-04-01
ITTO960477A0 (it) 1996-06-03
WO1996039224A1 (en) 1996-12-12
ZA964658B (en) 1997-02-03
GR1002982B (el) 1998-10-01
GB2317115A (en) 1998-03-18
IE960374A1 (en) 1996-12-11
FR2736837A1 (fr) 1997-01-24
ITTO960477A1 (it) 1997-12-03
GB2317115B (en) 1999-08-04
JPH11506684A (ja) 1999-06-15
JP4616309B2 (ja) 2011-01-19
KR19990022342A (ko) 1999-03-25
US20050171464A1 (en) 2005-08-04
GR960100178A (el) 1997-02-28
ATA903696A (de) 2001-10-15
JP2007237002A (ja) 2007-09-20
US6881208B1 (en) 2005-04-19
CA2219736A1 (en) 1996-12-12
CA2219736C (en) 2008-02-12
NL1003274C2 (nl) 1998-11-03
CA2613061A1 (en) 1996-12-12
CN1118308C (zh) 2003-08-20
CH690751A5 (de) 2001-01-15
AU6257896A (en) 1996-12-24
US20050131337A1 (en) 2005-06-16
SE9704103D0 (sv) 1997-11-10
CN1187142A (zh) 1998-07-08
BR9609137B1 (pt) 2010-06-29
AT409088B (de) 2002-05-27
BR9609137A (pt) 1999-02-17
KR100431364B1 (ko) 2004-07-16
GB9725542D0 (en) 1998-02-04
SE9704103L (sv) 1997-11-10
JP2005261970A (ja) 2005-09-29

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