IT1302012B1 - Derivati di rantes e loro applicazioni terapeutiche. - Google Patents
Derivati di rantes e loro applicazioni terapeutiche.Info
- Publication number
- IT1302012B1 IT1302012B1 ITMI981866A IT1302012B1 IT 1302012 B1 IT1302012 B1 IT 1302012B1 IT MI981866 A ITMI981866 A IT MI981866A IT 1302012 B1 IT1302012 B1 IT 1302012B1
- Authority
- IT
- Italy
- Prior art keywords
- rantes
- loop
- wild
- mutants
- amino acid
- Prior art date
Links
- 102000001327 Chemokine CCL5 Human genes 0.000 title abstract 9
- 108010055166 Chemokine CCL5 Proteins 0.000 title abstract 9
- 230000002401 inhibitory effect Effects 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 230000035772 mutation Effects 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 2
- 125000003729 nucleotide group Chemical group 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- 102000009410 Chemokine receptor Human genes 0.000 abstract 1
- 108050000299 Chemokine receptor Proteins 0.000 abstract 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000001088 anti-asthma Effects 0.000 abstract 1
- 230000036436 anti-hiv Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000924 antiasthmatic agent Substances 0.000 abstract 1
- 239000002559 chemokine receptor antagonist Substances 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000010534 mechanism of action Effects 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000009465 prokaryotic expression Effects 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (17)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98MI001866 IT1302012B1 (it) | 1998-08-07 | 1998-08-07 | Derivati di rantes e loro applicazioni terapeutiche. |
| AU24155/99A AU2415599A (en) | 1997-12-23 | 1998-12-21 | Rantes mutants and therapeutic applications thereof |
| AT98966650T ATE308616T1 (de) | 1997-12-23 | 1998-12-21 | Rantes mutanten und deren therapeutische verwendungen |
| DE69832197T DE69832197T2 (de) | 1997-12-23 | 1998-12-21 | Rantes-mutanten und therapeutische anwendungen davon |
| ES03027936T ES2247475T3 (es) | 1997-12-23 | 1998-12-21 | Mutantes de rantes y sus aplicaciones terapeuticas. |
| ES98966650T ES2247738T3 (es) | 1997-12-23 | 1998-12-21 | Mutantes de rantes y sus aplicaciones terapeuticas. |
| AT03027936T ATE308617T1 (de) | 1997-12-23 | 1998-12-21 | Rantes mutanten und deren therapeutischen anwendungen |
| DE69832216T DE69832216T2 (de) | 1997-12-23 | 1998-12-21 | RANTES-Mutanten und therapeutische Anwendungen davon |
| PCT/EP1998/008354 WO1999033989A2 (en) | 1997-12-23 | 1998-12-21 | Rantes mutants and therapeutic applications thereof |
| EP03027936A EP1431391B1 (en) | 1997-12-23 | 1998-12-21 | Rantes mutants and therapeutic applications thereof |
| EP98966650A EP1040191B1 (en) | 1997-12-23 | 1998-12-21 | Rantes mutants and therapeutic applications thereof |
| JP2000526645A JP4323094B2 (ja) | 1997-12-23 | 1998-12-21 | Ｒａｎｔｅｓ変異体およびその治療用途 |
| CA002316447A CA2316447C (en) | 1997-12-23 | 1998-12-21 | Rantes mutants and therapeutic applications thereof |
| DK03027936T DK1431391T3 (da) | 1997-12-23 | 1998-12-21 | RANTES-mutanter og terapeutiske anvendelser heraf |
| DK98966650T DK1040191T3 (da) | 1997-12-23 | 1998-12-21 | RANTES-mutanter og terapeutiske anvendelser heraf |
| US09/581,070 US6608177B1 (en) | 1997-12-23 | 1999-07-08 | Rantes mutants and therapeutic applications thereof |
| US10/400,487 US7164000B2 (en) | 1997-12-23 | 2003-03-28 | RANTES mutants and therapeutic applications thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT98MI001866 IT1302012B1 (it) | 1998-08-07 | 1998-08-07 | Derivati di rantes e loro applicazioni terapeutiche. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI981866A0 ITMI981866A0 (it) | 1998-08-07 |
| ITMI981866A1 ITMI981866A1 (it) | 2000-02-07 |
| IT1302012B1 true IT1302012B1 (it) | 2000-07-20 |
Family
ID=11380640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT98MI001866 IT1302012B1 (it) | 1997-12-23 | 1998-08-07 | Derivati di rantes e loro applicazioni terapeutiche. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1302012B1 (it) |
-
1998
- 1998-08-07 IT IT98MI001866 patent/IT1302012B1/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI981866A1 (it) | 2000-02-07 |
| ITMI981866A0 (it) | 1998-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |