IT7831286A0 - Derivati della esaidroazepina, piperidina e pirrolidina. - Google Patents

Derivati della esaidroazepina, piperidina e pirrolidina.

Info

Publication number
IT7831286A0
IT7831286A0 IT7831286A IT3128678A IT7831286A0 IT 7831286 A0 IT7831286 A0 IT 7831286A0 IT 7831286 A IT7831286 A IT 7831286A IT 3128678 A IT3128678 A IT 3128678A IT 7831286 A0 IT7831286 A0 IT 7831286A0
Authority
IT
Italy
Prior art keywords
hexhydroazepine
pyrrolidine
piperidine
derivatives
Prior art date
Application number
IT7831286A
Other languages
English (en)
Other versions
IT1102761B (it
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of IT7831286A0 publication Critical patent/IT7831286A0/it
Application granted granted Critical
Publication of IT1102761B publication Critical patent/IT1102761B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
IT31286/78A 1977-12-22 1978-12-22 Derivati della esaidroazepina, piperidina e pirrolidina IT1102761B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB53370/77A GB1593888A (en) 1977-12-22 1977-12-22 Hexahydroazepine piperidine and pyrrolidine derivatives

Publications (2)

Publication Number Publication Date
IT7831286A0 true IT7831286A0 (it) 1978-12-22
IT1102761B IT1102761B (it) 1985-10-07

Family

ID=10467561

Family Applications (1)

Application Number Title Priority Date Filing Date
IT31286/78A IT1102761B (it) 1977-12-22 1978-12-22 Derivati della esaidroazepina, piperidina e pirrolidina

Country Status (33)

Country Link
US (2) US4197239A (it)
EP (1) EP0003253B1 (it)
JP (1) JPS5488286A (it)
AR (1) AR221710A1 (it)
AT (1) AT373586B (it)
AU (1) AU519653B2 (it)
CA (2) CA1113092A (it)
CS (1) CS207748B2 (it)
CY (2) CY1144A (it)
DD (2) DD141308A5 (it)
DE (1) DE2862139D1 (it)
DK (1) DK156302C (it)
EG (1) EG13745A (it)
ES (2) ES476160A1 (it)
FI (1) FI70575C (it)
GB (1) GB1593888A (it)
GR (1) GR64029B (it)
HK (2) HK18182A (it)
HU (1) HU181997B (it)
IE (1) IE47631B1 (it)
IL (1) IL55924A (it)
IN (1) IN150193B (it)
IT (1) IT1102761B (it)
KE (2) KE3207A (it)
MX (1) MX5628E (it)
MY (2) MY8200278A (it)
NZ (1) NZ188863A (it)
PH (2) PH14412A (it)
PL (1) PL126008B1 (it)
PT (1) PT68962A (it)
SU (1) SU1301311A3 (it)
YU (1) YU40543B (it)
ZA (1) ZA786244B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE11046T1 (de) * 1979-07-03 1985-01-15 John Wyeth & Brother Limited Verfahren zur herstellung von 2-oxo- und 2unsubstituierten hexahydroazepinderivaten.
IE54154B1 (en) * 1981-12-02 1989-07-05 Wyeth John & Brother Ltd M-hydroxyphenyl substituted compounds
US5665754A (en) * 1993-09-20 1997-09-09 Glaxo Wellcome Inc. Substituted pyrrolidines
SE0001438D0 (sv) 2000-04-18 2000-04-18 Axon Chemicals Bv New chemical compounds and their use in therapy
KR100421282B1 (ko) * 2001-08-22 2004-03-09 부광약품 주식회사 1-메틸헥사히드로-4-아제피논 염산염의 제조방법
RU2378258C2 (ru) * 2004-07-13 2010-01-10 Ф. Хоффманн-Ля Рош Аг Производные сульфонамида

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2524643A (en) * 1947-12-04 1950-10-03 Maltbie Lab Inc 3-phenyl-2-piperidones
US3149123A (en) * 1961-01-04 1964-09-15 Parke Davis & Co 1, 3-dialkyl-3-oxyphenylpyrrolidine compounds
NL265485A (it) * 1961-06-02
FR1337793A (fr) * 1962-06-19 1963-09-20 Parke Davis & Co Composés de pyrrolidine et procédé de préparation de ces composés
GB1285025A (en) * 1968-08-16 1972-08-09 Wyeth John & Brother Ltd Hexahydroazepines
CH526535A (de) * 1970-02-05 1972-08-15 Sandoz Ag Verfahren zur Herstellung neuer Pyrrolidin-1-carboxamidinderivate
CH526536A (de) * 1970-02-05 1972-08-15 Sandoz Ag Verfahren zur Herstellung neuer 3-Phenylpyrrolidinderivate
CH526534A (de) * 1970-02-05 1972-08-15 Sandoz Ag Verfahren zur Herstellung neuer Pyrrolidin-1-carboxamidinderivate
US3729465A (en) * 1971-02-03 1973-04-24 Wyeth John & Brother Ltd Hexahydroazepines
JPS4911844A (it) * 1972-05-09 1974-02-01
BE850777A (fr) * 1976-01-28 1977-07-26 Sandoz Sa Nouveaux derives de la pyrrolidine

Also Published As

Publication number Publication date
CS207748B2 (en) 1981-08-31
SU1301311A3 (ru) 1987-03-30
CY1144A (en) 1982-09-10
MX5628E (es) 1983-11-15
PH14517A (en) 1981-08-26
KE3207A (en) 1982-05-21
CA1113465A (en) 1981-12-01
PT68962A (en) 1979-01-01
IL55924A0 (en) 1979-01-31
US4197239A (en) 1980-04-08
IN150193B (it) 1982-08-14
DK156302C (da) 1989-12-11
DD141308A5 (de) 1980-04-23
PH14412A (en) 1981-07-09
HK18082A (en) 1982-05-07
ZA786244B (en) 1980-06-25
FI70575B (fi) 1986-06-06
FI783922A7 (fi) 1979-06-23
DD149515A5 (de) 1981-07-15
IT1102761B (it) 1985-10-07
GB1593888A (en) 1981-07-22
AU4147978A (en) 1979-06-28
MY8200279A (en) 1982-12-31
ES476160A1 (es) 1979-11-16
PL126008B1 (en) 1983-06-30
JPS64392B2 (it) 1989-01-06
NZ188863A (en) 1982-03-16
EP0003253B1 (en) 1982-12-22
HU181997B (en) 1983-11-28
EG13745A (en) 1983-03-31
YU299778A (en) 1983-12-31
AT373586B (de) 1984-02-10
GR64029B (en) 1980-01-19
FI70575C (fi) 1986-09-24
IE47631B1 (en) 1984-05-16
ES481125A1 (es) 1980-02-01
ATA898578A (de) 1983-06-15
JPS5488286A (en) 1979-07-13
MY8200278A (en) 1982-12-31
DK546578A (da) 1979-06-23
YU40543B (en) 1986-02-28
US4197241A (en) 1980-04-08
AU519653B2 (en) 1981-12-17
CA1113092A (en) 1981-11-24
PL211970A1 (it) 1980-02-25
DK156302B (da) 1989-07-31
HK18182A (en) 1982-05-07
AR221710A1 (es) 1981-03-13
DE2862139D1 (en) 1983-01-27
IL55924A (en) 1982-01-31
KE3206A (en) 1982-05-21
IE782252L (en) 1979-06-22
CY1145A (en) 1982-09-10
EP0003253A1 (en) 1979-08-08

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