IT7926603A0 - Difenilbutilpiperazincarbossammidi, loro sali di addizione con acidi e composizioni farmaceutiche; procedimenti di fabbricazione ed uso. - Google Patents
Difenilbutilpiperazincarbossammidi, loro sali di addizione con acidi e composizioni farmaceutiche; procedimenti di fabbricazione ed uso.Info
- Publication number
- IT7926603A0 IT7926603A0 IT7926603A IT2660379A IT7926603A0 IT 7926603 A0 IT7926603 A0 IT 7926603A0 IT 7926603 A IT7926603 A IT 7926603A IT 2660379 A IT2660379 A IT 2660379A IT 7926603 A0 IT7926603 A0 IT 7926603A0
- Authority
- IT
- Italy
- Prior art keywords
- diphenylbutylpiperazincarboxamides
- manufacturing
- pharmaceutical compositions
- addition salts
- use procedures
- Prior art date
Links
- 230000002378 acidificating effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/194—Radicals derived from thio- or thiono carboxylic acids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L1/00—Enclosures; Chambers
- B01L1/52—Transportable laboratories; Field kits
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7810971 | 1978-10-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT7926603A0 true IT7926603A0 (it) | 1979-10-18 |
| IT1207269B IT1207269B (it) | 1989-05-17 |
Family
ID=20336152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT7926603A IT1207269B (it) | 1978-10-20 | 1979-10-18 | Difenilbutilpiperazincarbossammidi, loro sali di addizione con acidi e composizioni farmaceutiche; procedimenti di fabbricazione ed uso. |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US4308387A (it) |
| JP (1) | JPS5557572A (it) |
| AT (1) | AT376666B (it) |
| AU (1) | AU529260B2 (it) |
| BE (1) | BE879528A (it) |
| CA (1) | CA1130807A (it) |
| CH (1) | CH643247A5 (it) |
| DE (1) | DE2941880A1 (it) |
| DK (1) | DK149057C (it) |
| ES (1) | ES485188A1 (it) |
| FI (1) | FI73986C (it) |
| FR (1) | FR2439187A1 (it) |
| GB (1) | GB2037745B (it) |
| HK (1) | HK57184A (it) |
| IT (1) | IT1207269B (it) |
| LU (1) | LU81807A1 (it) |
| NL (2) | NL190160C (it) |
| NO (1) | NO154582C (it) |
| NZ (1) | NZ191867A (it) |
| SE (1) | SE448730B (it) |
| SG (1) | SG7384G (it) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE791501A (fr) * | 1971-11-19 | 1973-05-17 | Albert Ag Chem Werke | Diamines cycliques n,n'-disubstituees et leur procede de preparation |
| US4492698A (en) * | 1980-06-16 | 1985-01-08 | Bjoerk Anders K | Diphenylbutyl-1-acylpiperazines |
| AU562546B2 (en) * | 1981-12-02 | 1987-06-11 | Ferrosan A.B. | 1-piperazinocarboxylates, process for their preparation and pharmaceutical compositions containing them |
| US4543352A (en) * | 1983-04-29 | 1985-09-24 | William H. Rorer, Inc. | Naphthalene aminoalkylene ethers and thioethers, and their pharmaceutical uses |
| AT387572B (de) * | 1983-05-20 | 1989-02-10 | Ferrosan Ab | Verfahren zur herstellung von neuen 4-(4,4-bis-(p-fluorphenyl)-butyl)-1-carbophenox -piperazinen und von 1-piperazincarboxamiden |
| ES8502099A1 (es) | 1983-08-02 | 1984-12-16 | Espanola Farma Therapeut | Procedimiento de obtencion de nuevos compuestos derivados de la difenil-metilen-etilamina. |
| SE8304361D0 (sv) * | 1983-08-10 | 1983-08-10 | Ferrosan Ab | Novel 1-acylpiperazine derivatives novel 1-acylpiperazine derivatives |
| FR2558162B1 (fr) * | 1984-01-17 | 1986-04-25 | Adir | Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant |
| SE8500573D0 (sv) * | 1985-02-08 | 1985-02-08 | Ferrosan Ab | Novel piperazinecarboxamides having a phenoxyalkyl or thiophenoxyalkyl side chain |
| US4960776A (en) * | 1987-01-28 | 1990-10-02 | A. H. Robins Company, Inc. | 4-aryl-N-(alkylaminoalkyl, heterocyclicamino and heterocyclicamino)alkyl)-1-piperazinecarboxamides |
| WO1990013539A1 (fr) * | 1989-04-28 | 1990-11-15 | Meiji Seika Kaisha, Ltd. | Nouveaux derives de piperazine a substitution n et medicament de traitement des troubles fonctionnels du cerveau |
| FR2673182A1 (fr) * | 1991-02-22 | 1992-08-28 | Univ Caen | Piperazines n,n'-disubstituees, leur procede de preparation et leur application en therapeutique. |
| SE9100860D0 (sv) * | 1991-03-22 | 1991-03-22 | Kabi Pharmacia Ab | New use |
| SE9201239D0 (sv) * | 1992-04-21 | 1992-04-21 | Kabi Pharmacia Ab | Agents for treating substance abuse disorders |
| DE4219973A1 (de) * | 1992-06-19 | 1993-12-23 | Basf Ag | N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung |
| SE9202266D0 (sv) * | 1992-07-31 | 1992-07-31 | Kabi Pharmacia Ab | Novel piperazine carboxamides |
| DE4307181C1 (de) * | 1993-03-08 | 1994-11-10 | Dresden Arzneimittel | Verfahren zur Herstellung von 5H-Dibenz/b,f/azepin-5-carboxamid |
| DE4341403A1 (de) * | 1993-12-04 | 1995-06-08 | Basf Ag | N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung |
| JP3274579B2 (ja) * | 1995-01-12 | 2002-04-15 | 住友製薬株式会社 | 脳血管障害に伴う精神症候治療剤 |
| DE29815747U1 (de) | 1998-09-02 | 2000-01-05 | Ramsauer, Dieter, 42555 Velbert | Anschraubscharnier mit Raststellung |
| GB9923748D0 (en) * | 1999-10-07 | 1999-12-08 | Glaxo Group Ltd | Chemical compounds |
| USRE39921E1 (en) | 1999-10-07 | 2007-11-13 | Smithkline Beecham Corporation | Chemical compounds |
| GB0025354D0 (en) * | 2000-10-17 | 2000-11-29 | Glaxo Group Ltd | Chemical compounds |
| GB0108594D0 (en) * | 2001-04-05 | 2001-05-23 | Glaxo Group Ltd | Chemical compounds |
| US20030068375A1 (en) | 2001-08-06 | 2003-04-10 | Curtis Wright | Pharmaceutical formulation containing gelling agent |
| US7332182B2 (en) | 2001-08-06 | 2008-02-19 | Purdue Pharma L.P. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and irritant |
| US7157103B2 (en) | 2001-08-06 | 2007-01-02 | Euro-Celtique S.A. | Pharmaceutical formulation containing irritant |
| US7141250B2 (en) * | 2001-08-06 | 2006-11-28 | Euro-Celtique S.A. | Pharmaceutical formulation containing bittering agent |
| US20030044458A1 (en) * | 2001-08-06 | 2003-03-06 | Curtis Wright | Oral dosage form comprising a therapeutic agent and an adverse-effect agent |
| US7842307B2 (en) * | 2001-08-06 | 2010-11-30 | Purdue Pharma L.P. | Pharmaceutical formulation containing opioid agonist, opioid antagonist and gelling agent |
| GB0203020D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| JP2005522436A (ja) * | 2002-02-08 | 2005-07-28 | グラクソ グループ リミテッド | ピペリジルカルボキシアミド誘導体またはそのタキキニン介在疾患の治療における使用 |
| GB0203022D0 (en) * | 2002-02-08 | 2002-03-27 | Glaxo Group Ltd | Chemical compounds |
| ES2653568T3 (es) | 2004-06-12 | 2018-02-07 | Collegium Pharmaceutical, Inc. | Formulaciones de fármacos para la prevención del abuso |
| JP4823673B2 (ja) * | 2005-12-15 | 2011-11-24 | タカラベルモント株式会社 | ショックレス弁を接続した油圧回路 |
| JP2010169206A (ja) * | 2009-01-23 | 2010-08-05 | Finesinter Co Ltd | ノンリークショックレス電磁比例制御弁 |
| US10668060B2 (en) | 2009-12-10 | 2020-06-02 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
| PL2826467T3 (pl) | 2010-12-22 | 2018-01-31 | Purdue Pharma Lp | Zamknięte, zabezpieczone przed manipulowaniem formy dozowania o kontrolowanym uwalnianiu |
| PH12013501345A1 (en) | 2010-12-23 | 2022-10-24 | Purdue Pharma Lp | Tamper resistant solid oral dosage forms |
| PE20151301A1 (es) | 2013-02-05 | 2015-09-16 | Purdue Pharma Lp | Formulaciones farmaceuticas resistentes a la manipulacion indebida |
| US10751287B2 (en) | 2013-03-15 | 2020-08-25 | Purdue Pharma L.P. | Tamper resistant pharmaceutical formulations |
| US9737530B1 (en) | 2016-06-23 | 2017-08-22 | Collegium Pharmaceutical, Inc. | Process of making stable abuse-deterrent oral formulations |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL137318C (it) * | 1964-06-09 | |||
| JPS518283A (en) * | 1974-07-09 | 1976-01-23 | Kyorin Seiyaku Kk | 11 * 33 fuenirupuropiru * 44 karubamoirupiperajinjudotaino seizoho |
| JPS5346988A (en) * | 1976-10-07 | 1978-04-27 | Kyorin Seiyaku Kk | Piperadine derivative |
-
1979
- 1979-10-15 NO NO793315A patent/NO154582C/no unknown
- 1979-10-16 DE DE19792941880 patent/DE2941880A1/de active Granted
- 1979-10-18 CH CH938379A patent/CH643247A5/de not_active IP Right Cessation
- 1979-10-18 IT IT7926603A patent/IT1207269B/it active Protection Beyond IP Right Term
- 1979-10-18 US US06/086,068 patent/US4308387A/en not_active Expired - Lifetime
- 1979-10-18 FR FR7925953A patent/FR2439187A1/fr active Granted
- 1979-10-18 FI FI793238A patent/FI73986C/fi not_active IP Right Cessation
- 1979-10-19 JP JP13581779A patent/JPS5557572A/ja active Granted
- 1979-10-19 NL NLAANVRAGE7907741,A patent/NL190160C/xx not_active IP Right Cessation
- 1979-10-19 AU AU51984/79A patent/AU529260B2/en not_active Expired
- 1979-10-19 ES ES485188A patent/ES485188A1/es not_active Expired
- 1979-10-19 SE SE7908701A patent/SE448730B/sv not_active IP Right Cessation
- 1979-10-19 NZ NZ191867A patent/NZ191867A/xx unknown
- 1979-10-19 LU LU81807A patent/LU81807A1/de unknown
- 1979-10-19 AT AT0683479A patent/AT376666B/de not_active IP Right Cessation
- 1979-10-19 CA CA338,084A patent/CA1130807A/en not_active Expired
- 1979-10-19 GB GB7936297A patent/GB2037745B/en not_active Expired
- 1979-10-19 BE BE0/197737A patent/BE879528A/fr not_active IP Right Cessation
- 1979-10-19 DK DK442779A patent/DK149057C/da not_active IP Right Cessation
-
1981
- 1981-01-23 US US06/227,690 patent/US4385057A/en not_active Expired - Lifetime
-
1982
- 1982-09-15 US US06/418,685 patent/US4447433A/en not_active Expired - Lifetime
-
1984
- 1984-01-26 SG SG73/84A patent/SG7384G/en unknown
- 1984-07-26 HK HK571/84A patent/HK57184A/xx not_active IP Right Cessation
-
1994
- 1994-03-23 NL NL940004C patent/NL940004I1/nl unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ITCP | Complementary protection certificate |
Free format text: CCP 358 |
|
| MEDD | Supplementary protection certificate for pharmaceutical products: granted |
Free format text: CCP 358, 19920518; KABI PHARMACIA AB |
|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971030 |