IT8349574A0 - Composti tripeptidici contententi acido piroglutaminico e triptofano, procedimentio di produzione ed applicazioni terapeutiche - Google Patents

Composti tripeptidici contententi acido piroglutaminico e triptofano, procedimentio di produzione ed applicazioni terapeutiche

Info

Publication number
IT8349574A0
IT8349574A0 IT8349574A IT4957483A IT8349574A0 IT 8349574 A0 IT8349574 A0 IT 8349574A0 IT 8349574 A IT8349574 A IT 8349574A IT 4957483 A IT4957483 A IT 4957483A IT 8349574 A0 IT8349574 A0 IT 8349574A0
Authority
IT
Italy
Prior art keywords
tryptophan
compounds containing
therapeutic applications
production procedure
tripeptide compounds
Prior art date
Application number
IT8349574A
Other languages
English (en)
Other versions
IT1172391B (it
Inventor
Materazzi Mario
De Luca Giovanna
Di Stazio Giovanni
Politi Vincenzoe Margon Andrea
Original Assignee
Polifarma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polifarma Spa filed Critical Polifarma Spa
Priority to IT49574/83A priority Critical patent/IT1172391B/it
Publication of IT8349574A0 publication Critical patent/IT8349574A0/it
Priority to US06/679,477 priority patent/US4619916A/en
Priority to DE8484830333T priority patent/DE3477383D1/de
Priority to EP84830333A priority patent/EP0148133B1/en
Priority to JP59270606A priority patent/JPS60156700A/ja
Application granted granted Critical
Publication of IT1172391B publication Critical patent/IT1172391B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0825—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT49574/83A 1983-12-23 1983-12-23 Composti tirpeptidici contenenti acido piroglutaminico e triptofano,procedimentio di produzione ed applicazioni terapeutiche IT1172391B (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT49574/83A IT1172391B (it) 1983-12-23 1983-12-23 Composti tirpeptidici contenenti acido piroglutaminico e triptofano,procedimentio di produzione ed applicazioni terapeutiche
US06/679,477 US4619916A (en) 1983-12-23 1984-12-07 Tripeptide compounds containing pyroglutamic acid and tryptophan, process for their production and therapeutic applications
DE8484830333T DE3477383D1 (en) 1983-12-23 1984-12-10 Tripeptide compounds containing pyroglutamic acid and tryptophan, process for their production and therapeutic applications
EP84830333A EP0148133B1 (en) 1983-12-23 1984-12-10 Tripeptide compounds containing pyroglutamic acid and tryptophan, process for their production and therapeutic applications
JP59270606A JPS60156700A (ja) 1983-12-23 1984-12-21 トリペプチド化合物、その製造法および医薬組成物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT49574/83A IT1172391B (it) 1983-12-23 1983-12-23 Composti tirpeptidici contenenti acido piroglutaminico e triptofano,procedimentio di produzione ed applicazioni terapeutiche

Publications (2)

Publication Number Publication Date
IT8349574A0 true IT8349574A0 (it) 1983-12-23
IT1172391B IT1172391B (it) 1987-06-18

Family

ID=11271066

Family Applications (1)

Application Number Title Priority Date Filing Date
IT49574/83A IT1172391B (it) 1983-12-23 1983-12-23 Composti tirpeptidici contenenti acido piroglutaminico e triptofano,procedimentio di produzione ed applicazioni terapeutiche

Country Status (5)

Country Link
US (1) US4619916A (it)
EP (1) EP0148133B1 (it)
JP (1) JPS60156700A (it)
DE (1) DE3477383D1 (it)
IT (1) IT1172391B (it)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61148198A (ja) * 1984-12-22 1986-07-05 Ajinomoto Co Inc 新規トリペプチド化合物および甘味剤
IT1184164B (it) * 1985-03-19 1987-10-22 Eniricerche Spa Triptidi ad azione ipotensiva e procedimento per la loro sintesi
IT1186733B (it) * 1985-06-05 1987-12-16 Eniricerche Spa Composti tripeptidici ad azione ipotensiva
IT1190383B (it) * 1985-08-01 1988-02-16 Eniricerche Spa Sostanze peptidominetiche ad azione ipotensiva
JP2513197B2 (ja) * 1986-01-21 1996-07-03 日本新薬株式会社 ピログルタミド誘導体
FR2597100A1 (fr) * 1986-01-21 1987-10-16 Nippon Shinyaku Co Ltd Derives du pyroglutamide
JPH06104079B2 (ja) * 1988-07-14 1994-12-21 日東紡績株式会社 新規な酵素活性測定用基質
IT1237474B (it) * 1989-10-05 1993-06-07 Polifarma Spa Composti tripeptidici e loro uso farmaceutico come immuno-modulatori
ATE277619T1 (de) * 1990-05-10 2004-10-15 Atsuo F Fukunaga Verwendung von adenosin und adenosinderivaten für analgesia
IT1242002B (it) * 1990-10-03 1994-02-02 Polifarma Spa Composti con attivita' farmacologica antiipertensiva, analgesica, immunomodulante e antiinfiammatoria, che presentano nella molecola una sequenza di tre radicali, essendo alfa-amminoacido quello centrale
US5504071A (en) * 1990-10-03 1996-04-02 Polifarma S.P.A. Compounds with a sequence of three radicals, the central one being α-a
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
RU2107691C1 (ru) * 1995-03-02 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
ES2185782T3 (es) * 1995-07-26 2003-05-01 Firmenich & Cie Productos aromatizados y procedimiento para su preparacion.
US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis
IL137820A (en) * 2000-08-10 2009-06-15 S I S Shulov Inst For Science Pharmaceutical composition for topical administration comprising an analgesic peptide
US20100190723A1 (en) * 2007-03-23 2010-07-29 Hiroo Sanada Preventive or therapeutic composition for liver disease
WO2010032322A1 (ja) * 2008-09-22 2010-03-25 日清ファルマ株式会社 抗炎症性ペプチド
CN103554221B (zh) * 2010-04-29 2015-09-02 上海医药工业研究院 一组蛇毒来源的活性肽的制备方法
HUE030152T2 (en) 2011-03-28 2017-04-28 S I S Shulov Innovative Science Ltd A method for treating skin diseases
US10834946B2 (en) * 2013-01-22 2020-11-17 Mars, Incorporated Flavor composition and edible compositions containing same
CA3017740A1 (en) 2016-03-16 2017-09-21 Pearlie BURNETTE Small molecules against cereblon to enhance effector t cell function
WO2019186561A1 (en) 2018-03-29 2019-10-03 S.I.S Shulov Innovative Science Ltd. Pharmaceutical compositions for inhibiting inflammatory cytokines
EA202190248A1 (ru) 2018-07-11 2021-06-16 Х. Ли Моффитт Кэнсер Сентер Энд Рисерч Инститьют, Инк. Димерные иммуномодулирующие соединения против механизмов на основе цереблона
EP4034147A4 (en) 2019-09-26 2023-10-18 S.I.S. Shulov Innovative Science Ltd. COMPOSITIONS AND METHODS FOR TREATING DEGENERATIVE, AGE-RELATED AND TRAUMA-INDUCED DISORDERS
AU2020356605A1 (en) 2019-09-26 2022-04-14 S.I.S. Shulov Innovative Science Ltd. Anti-aging compositions and methods of use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2238700B1 (it) * 1973-07-24 1977-10-14 Takeda Chemical Industries Ltd

Also Published As

Publication number Publication date
JPS60156700A (ja) 1985-08-16
JPH0146519B2 (it) 1989-10-09
EP0148133A2 (en) 1985-07-10
US4619916A (en) 1986-10-28
EP0148133B1 (en) 1989-03-22
DE3477383D1 (en) 1989-04-27
IT1172391B (it) 1987-06-18
EP0148133A3 (en) 1987-04-15

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19941228