IT8423264A0 - Nuovo processo per la preparazione dell'acido 2(4-fluorofenil)alfa-metil-5-benzoxazoloacetico. - Google Patents
Nuovo processo per la preparazione dell'acido 2(4-fluorofenil)alfa-metil-5-benzoxazoloacetico.Info
- Publication number
- IT8423264A0 IT8423264A0 IT8423264A IT2326484A IT8423264A0 IT 8423264 A0 IT8423264 A0 IT 8423264A0 IT 8423264 A IT8423264 A IT 8423264A IT 2326484 A IT2326484 A IT 2326484A IT 8423264 A0 IT8423264 A0 IT 8423264A0
- Authority
- IT
- Italy
- Prior art keywords
- fluorophenyl
- alpha
- methyl
- preparation
- new process
- Prior art date
Links
- ARPYQKTVRGFPIS-UHFFFAOYSA-N 2-[2-(4-fluorophenyl)-1,3-benzoxazol-5-yl]propanoic acid Chemical compound N=1C2=CC(C(C(O)=O)C)=CC=C2OC=1C1=CC=C(F)C=C1 ARPYQKTVRGFPIS-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D263/57—Aryl or substituted aryl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23264/84A IT1177017B (it) | 1984-10-22 | 1984-10-22 | Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico |
| DE8585112699T DE3585022D1 (de) | 1984-10-22 | 1985-10-07 | Verfahren zur herstellung von 2-(4-fluorphenyl)-alpha-methyl-5-benzoxazolessigsaeure. |
| EP85112699A EP0182061B1 (en) | 1984-10-22 | 1985-10-07 | New process for preparing 2(4-fluorophenyl) alpha methyl-5-benzoxazole acetic acid |
| US06/784,892 US4652654A (en) | 1984-10-22 | 1985-10-07 | Process for preparing 2(4-fluorophenyl)alpha-methyl-5-benzoxazole acetic acid |
| AT85112699T ATE70832T1 (de) | 1984-10-22 | 1985-10-07 | Verfahren zur herstellung von 2-(4-fluorphenyl)alpha-methyl-5-benzoxazolessigs|ure. |
| JP60231423A JPS61100574A (ja) | 1984-10-22 | 1985-10-18 | 2(4‐フルオロフエニル)α‐メチル‐5‐ベンゾオキサゾール酢酸の製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT23264/84A IT1177017B (it) | 1984-10-22 | 1984-10-22 | Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8423264A0 true IT8423264A0 (it) | 1984-10-22 |
| IT8423264A1 IT8423264A1 (it) | 1986-04-22 |
| IT1177017B IT1177017B (it) | 1987-08-26 |
Family
ID=11205428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT23264/84A IT1177017B (it) | 1984-10-22 | 1984-10-22 | Processo per la preparazione dell'acido 2(4-flurofenil)alfa-metil-5-benzox azoloacetico |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4652654A (it) |
| EP (1) | EP0182061B1 (it) |
| JP (1) | JPS61100574A (it) |
| AT (1) | ATE70832T1 (it) |
| DE (1) | DE3585022D1 (it) |
| IT (1) | IT1177017B (it) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1233836B (it) * | 1988-01-13 | 1992-04-21 | Euroresearch Srl | Sali idrosolubili dell'acido (+)2-(4 fluorofenil)-alfa-metil-5 benzoxazolo acetato. |
| GB9312853D0 (en) * | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
| US5922751A (en) * | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
| US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| US5665737B1 (en) * | 1994-10-12 | 1999-02-16 | Euro Celtique Sa | Substituted benzoxazoles |
| US6372770B1 (en) | 1994-10-12 | 2002-04-16 | Euro-Celtique, S.A. | Benzoxazoles |
| AU699489B2 (en) * | 1994-10-12 | 1998-12-03 | Euro-Celtique S.A. | Novel benzoxazoles |
| EP0799040B1 (en) * | 1994-12-13 | 2003-08-20 | Euroceltique S.A. | Trisubstituted thioxanthines |
| US6025361A (en) * | 1994-12-13 | 2000-02-15 | Euro-Celtique, S.A. | Trisubstituted thioxanthines |
| JPH10508032A (ja) * | 1994-12-13 | 1998-08-04 | ユーロ−セルティーク,エス.エイ. | アリールチオキサンチン類 |
| US6166041A (en) * | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
| US6075016A (en) * | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
| US5864037A (en) | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
| US5744473A (en) * | 1996-09-16 | 1998-04-28 | Euro-Celtique, S.A. | PDE IV inhibitors: "bis-compounds" |
| CN1222513C (zh) | 1997-02-03 | 2005-10-12 | 富士写真菲林株式会社 | 卤化银彩色照相感光材料和其中所用的菲尼酮化合物以及这类化合物的制备方法 |
| US8865906B2 (en) * | 2009-05-15 | 2014-10-21 | Sanofi | Process for the preparation of a compound useful as an inhibitor of TAFIa |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1435721A (en) * | 1972-05-18 | 1976-05-12 | Lilly Industries Ltd | Benzoxazole derivatives |
| US3962452A (en) * | 1972-05-18 | 1976-06-08 | Lilly Industries, Ltd. | Benzoxazole derivatives as therapeutics |
| US4025636A (en) * | 1973-10-23 | 1977-05-24 | Lilly Industries, Ltd. | 2-(Optionally substituted)phenyl-5 or 6-substituted benzoxazoles |
-
1984
- 1984-10-22 IT IT23264/84A patent/IT1177017B/it active
-
1985
- 1985-10-07 DE DE8585112699T patent/DE3585022D1/de not_active Expired - Fee Related
- 1985-10-07 EP EP85112699A patent/EP0182061B1/en not_active Expired - Lifetime
- 1985-10-07 AT AT85112699T patent/ATE70832T1/de not_active IP Right Cessation
- 1985-10-07 US US06/784,892 patent/US4652654A/en not_active Expired - Lifetime
- 1985-10-18 JP JP60231423A patent/JPS61100574A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| US4652654A (en) | 1987-03-24 |
| DE3585022D1 (de) | 1992-02-06 |
| JPS61100574A (ja) | 1986-05-19 |
| IT8423264A1 (it) | 1986-04-22 |
| IT1177017B (it) | 1987-08-26 |
| EP0182061A1 (en) | 1986-05-28 |
| EP0182061B1 (en) | 1991-12-27 |
| ATE70832T1 (de) | 1992-01-15 |
| JPH0368026B2 (it) | 1991-10-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971029 |