FR2567540B1 - Procede de preparation d'un interferon leucocytaire humain alpha-2 - Google Patents

Procede de preparation d'un interferon leucocytaire humain alpha-2

Info

Publication number
FR2567540B1
FR2567540B1 FR8510816A FR8510816A FR2567540B1 FR 2567540 B1 FR2567540 B1 FR 2567540B1 FR 8510816 A FR8510816 A FR 8510816A FR 8510816 A FR8510816 A FR 8510816A FR 2567540 B1 FR2567540 B1 FR 2567540B1
Authority
FR
France
Prior art keywords
leukocyta
human
preparation
interferon alpha
interferon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8510816A
Other languages
English (en)
Other versions
FR2567540A1 (fr
Inventor
V G Debabov
J D Tsygankov
A J Chistoserdov
E D Sverdlov
L S Izotova
S V Kostrov
V E Sterkin
V P Kuznetsov
S V Belyaev
G S Monastyrskaya
I S Salomatina
G M Dolganov
S G Arsenian
S A Tsarev
J I Kozlov
A Y Strongin
V I Ogarkov
J A Ovchinnikov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST GENETIKI I SELEKTSII
Original Assignee
INST GENETIKI I SELEKTSII
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST GENETIKI I SELEKTSII filed Critical INST GENETIKI I SELEKTSII
Publication of FR2567540A1 publication Critical patent/FR2567540A1/fr
Application granted granted Critical
Publication of FR2567540B1 publication Critical patent/FR2567540B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/78—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Pseudomonas
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/142—Interferon

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FR8510816A 1984-07-13 1985-07-15 Procede de preparation d'un interferon leucocytaire humain alpha-2 Expired FR2567540B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU843757952A SU1364343A1 (ru) 1984-07-13 1984-07-13 Способ получени человеческого лейкоцитарного интерферона альфа-2

Publications (2)

Publication Number Publication Date
FR2567540A1 FR2567540A1 (fr) 1986-01-17
FR2567540B1 true FR2567540B1 (fr) 1988-10-14

Family

ID=21125646

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8510816A Expired FR2567540B1 (fr) 1984-07-13 1985-07-15 Procede de preparation d'un interferon leucocytaire humain alpha-2

Country Status (12)

Country Link
US (1) US4680260A (fr)
JP (1) JPS6156093A (fr)
BG (1) BG46981A1 (fr)
CA (1) CA1264294A (fr)
CH (1) CH666051A5 (fr)
DE (1) DE3524991A1 (fr)
FR (1) FR2567540B1 (fr)
GB (1) GB2163750B (fr)
HU (1) HU194316B (fr)
IN (1) IN162268B (fr)
IT (1) IT1201429B (fr)
SU (1) SU1364343A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
SU1703690A1 (ru) * 1986-04-30 1992-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Рекомбинантна плазмидна ДНК @ 22, кодирующа синтез интерферона @ -11 человека, и штамм бактерии РSеUDомоNаS Sp. -продуцент- интерферона @ -11 человека
RU2142508C1 (ru) * 1997-07-23 1999-12-10 Государственный научный центр вирусологии и биотехнологии "Вектор" Способ промышленного получения полипептида с биологической активностью лейкоцитарного интерферона альфа-2 человека
RU2140284C1 (ru) * 1998-07-06 1999-10-27 Государственное унитарное предприятие "Иммунопрепарат" Способ получения человеческого лейкоцитарного интерферона
CN1553954A (zh) * 2001-03-30 2004-12-08 ������������ʳƷ�ۺ��о��� 通过赋予药物抗性突变提高次级代谢物产率的方法
RU2203950C1 (ru) * 2002-01-15 2003-05-10 Общество с ограниченной ответственностью "Биотех" Штамм дрожжей pichia pastoris - продуцент лейкоцитарного интерферона-16 человека, рекомбинантная плазмидная днк phin и способ ее конструирования
RU2225722C1 (ru) * 2002-07-11 2004-03-20 Государственный научно-исследовательский институт особо чистых биопрепаратов Способ получения человеческого интерферона
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
RU2242516C1 (ru) * 2003-12-18 2004-12-20 Общество С Ограниченной Ответственностью "Фармапарк" Способ получения рекомбинантного человеческого интерферона альфа-2b, рекомбинантная плазмида и штамм продуцент для его осуществления
KR101183720B1 (ko) * 2004-01-16 2012-09-17 다우 글로벌 테크놀로지스 엘엘씨 슈도모나스 플루오레센스에서의 포유류 단백질의 발현
CN101031655A (zh) 2004-07-26 2007-09-05 陶氏环球技术公司 通过株工程改进蛋白表达的方法
UA100692C2 (ru) 2007-05-02 2013-01-25 Мериал Лимитед Днк-плазмиды, имеющие повышенную экспрессию и стабильность
KR101662574B1 (ko) 2007-11-28 2016-10-05 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 유인원 ｅ 아데노바이러스 ｓａｄｖ-39, -25.2, -26, -30, -37, 및 -38
EP2643465B1 (fr) 2010-11-23 2016-05-11 The Trustees Of The University Of Pennsylvania Adénovirus simiens de la sous-famille e a1321 et ses utilisations
AU2013262626B2 (en) 2012-05-18 2018-11-29 The Trustees Of The University Of Pennsylvania Subfamily E simian adenoviruses A1302, A1320, A1331 and A1337 and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE870188A (fr) * 1977-09-08 1979-03-05 Ici Ltd Procede microbiologique
US4530901A (en) * 1980-01-08 1985-07-23 Biogen N.V. Recombinant DNA molecules and their use in producing human interferon-like polypeptides
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
DE3176011D1 (en) * 1980-06-12 1987-04-23 Japan Found Cancer Plasmid
CH651308A5 (de) * 1980-07-01 1985-09-13 Hoffmann La Roche Interferone und deren herstellung.
DE3280127D1 (de) * 1981-03-27 1990-04-12 Ici Plc Genetisch modifizierte mikroorganismen.
DE3122216A1 (de) * 1981-06-04 1982-12-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung eines mikroorganismus, welcher (alpha)-galactosidase, aber keine invertase bildet, so erhaltener mikroorganismus und seine verwendung
DK368882A (da) * 1981-08-25 1983-02-26 Alan John Kingsman Expessions vektorer
FR2516094A1 (fr) * 1981-11-06 1983-05-13 Wellcome Found Vecteur de clonage recombinant, micro-organisme transforme par ce vecteur, bacteriophage et procede pour produire un polypeptide heterologue
CA1210714A (fr) * 1982-03-23 1986-09-02 Alan Sloma .alpha.-INTERFERON GX-1
NZ207925A (en) * 1983-04-25 1988-05-30 Genentech Inc Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins

Also Published As

Publication number Publication date
CA1264294A (fr) 1990-01-09
IT8521468A0 (it) 1985-07-08
IN162268B (fr) 1988-04-23
HU194316B (en) 1988-01-28
JPS6156093A (ja) 1986-03-20
IT1201429B (it) 1989-02-02
US4680260A (en) 1987-07-14
FR2567540A1 (fr) 1986-01-17
GB8517795D0 (en) 1985-08-21
DE3524991A1 (de) 1986-03-13
BG46981A1 (en) 1990-04-16
CH666051A5 (de) 1988-06-30
HUT39476A (en) 1986-09-29
GB2163750A (en) 1986-03-05
GB2163750B (en) 1987-09-16
SU1364343A1 (ru) 1988-01-07

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Legal Events

Date Code Title Description
ST Notification of lapse