IT8619456A1 - Analoghi di prostaglandine sostituiti con tiabicicloeptano aventi attivita' cardiovascolare - Google Patents

Analoghi di prostaglandine sostituiti con tiabicicloeptano aventi attivita' cardiovascolare

Info

Publication number
IT8619456A1
IT8619456A1 IT1986A19456A IT1945686A IT8619456A1 IT 8619456 A1 IT8619456 A1 IT 8619456A1 IT 1986A19456 A IT1986A19456 A IT 1986A19456A IT 1945686 A IT1945686 A IT 1945686A IT 8619456 A1 IT8619456 A1 IT 8619456A1
Authority
IT
Italy
Prior art keywords
thiabicycleeptan
prostaglandin analogs
cardiovascular activity
replaced
analogs replaced
Prior art date
Application number
IT1986A19456A
Other languages
English (en)
Other versions
IT8619456A0 (it
IT1188703B (it
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8619456A0 publication Critical patent/IT8619456A0/it
Publication of IT8619456A1 publication Critical patent/IT8619456A1/it
Application granted granted Critical
Publication of IT1188703B publication Critical patent/IT1188703B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IT19456/86A 1985-02-20 1986-02-19 Analoghi di prostaglandine sostituiti con tiabicicloeptano avenyi attivita' cardiovascolare IT1188703B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/703,624 US4588742A (en) 1985-02-20 1985-02-20 Thiabicycloheptane substituted prostaglandin analogs useful in the treatment of thrombotic disease

Publications (3)

Publication Number Publication Date
IT8619456A0 IT8619456A0 (it) 1986-02-19
IT8619456A1 true IT8619456A1 (it) 1987-08-19
IT1188703B IT1188703B (it) 1988-01-28

Family

ID=24826132

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19456/86A IT1188703B (it) 1985-02-20 1986-02-19 Analoghi di prostaglandine sostituiti con tiabicicloeptano avenyi attivita' cardiovascolare

Country Status (7)

Country Link
US (1) US4588742A (it)
JP (1) JPS61194087A (it)
CA (1) CA1268468C (it)
DE (1) DE3605296A1 (it)
FR (1) FR2581997B1 (it)
GB (1) GB2171098B (it)
IT (1) IT1188703B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735962A (en) * 1986-10-06 1988-04-05 E. R. Squibb & Sons, Inc. 7-thiabicycloheptane substituted diamide and its congener prostaglandin analogs
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
CN102379684B (zh) 2005-04-28 2014-11-19 普罗透斯数字保健公司 药物信息系统
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4187236A (en) * 1977-11-04 1980-02-05 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane compounds
US4220594A (en) * 1977-11-04 1980-09-02 E. R. Squibb & Sons, Inc. Hexa- and octahydro-4,7-epoxyisobenzofuran-1-ol and hexa- and octahydro-5,8-epoxy-1H-2-benzopyran-3-ol
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
EP0045118B1 (en) * 1979-01-05 1984-04-04 National Research Development Corporation Intermediates for the synthesis of bicyclo (2,2,1) heptanes and bicyclo (2,2,1) hept-2z-enes
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
ZA814307B (en) * 1980-07-01 1983-02-23 Nat Res Dev Prostaglandins

Also Published As

Publication number Publication date
IT8619456A0 (it) 1986-02-19
US4588742A (en) 1986-05-13
CA1268468A (en) 1990-05-01
JPS61194087A (ja) 1986-08-28
DE3605296A1 (de) 1986-08-21
GB8602539D0 (en) 1986-03-12
FR2581997A1 (fr) 1986-11-21
FR2581997B1 (fr) 1988-09-16
GB2171098B (en) 1988-06-29
IT1188703B (it) 1988-01-28
CA1268468C (en) 1990-05-01
GB2171098A (en) 1986-08-20

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950227