IT8620761A0 - Procedimento per la preparazione di 2-bromo-alfa-ergocriptina. - Google Patents

Procedimento per la preparazione di 2-bromo-alfa-ergocriptina.

Info

Publication number
IT8620761A0
IT8620761A0 IT8620761A IT2076186A IT8620761A0 IT 8620761 A0 IT8620761 A0 IT 8620761A0 IT 8620761 A IT8620761 A IT 8620761A IT 2076186 A IT2076186 A IT 2076186A IT 8620761 A0 IT8620761 A0 IT 8620761A0
Authority
IT
Italy
Prior art keywords
ergocriptine
alfa
bromo
procedure
preparation
Prior art date
Application number
IT8620761A
Other languages
English (en)
Other versions
IT8620761A1 (it
IT1191806B (it
Inventor
Gabor Megyeri
Tibor Keve
Janos Galambos
Lajos Kovacs Jr
Bela Stefko
Erik Bogsch
Fereno Trischler
Original Assignee
Tichter Gedeon Vegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tichter Gedeon Vegyeszeti Gyar filed Critical Tichter Gedeon Vegyeszeti Gyar
Publication of IT8620761A0 publication Critical patent/IT8620761A0/it
Publication of IT8620761A1 publication Critical patent/IT8620761A1/it
Application granted granted Critical
Publication of IT1191806B publication Critical patent/IT1191806B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT20761/86A 1985-06-12 1986-06-11 Procedimento per la preparazione di 2-bromo-alfa-ergocriptina IT1191806B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852300A HU193317B (en) 1985-06-12 1985-06-12 Process for producing 2-bromo-alpha-ergochristin

Publications (3)

Publication Number Publication Date
IT8620761A0 true IT8620761A0 (it) 1986-06-11
IT8620761A1 IT8620761A1 (it) 1987-12-11
IT1191806B IT1191806B (it) 1988-03-23

Family

ID=10958743

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20761/86A IT1191806B (it) 1985-06-12 1986-06-11 Procedimento per la preparazione di 2-bromo-alfa-ergocriptina

Country Status (13)

Country Link
US (1) US4697017A (it)
JP (1) JPS61286390A (it)
BE (1) BE904897A (it)
CA (1) CA1256103A (it)
CH (1) CH667092A5 (it)
CS (1) CS262670B2 (it)
DE (1) DE3619617A1 (it)
ES (1) ES8707236A1 (it)
FR (1) FR2583419B1 (it)
GB (1) GB2176479B (it)
HU (1) HU193317B (it)
IT (1) IT1191806B (it)
YU (1) YU100886A (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU196394B (en) * 1986-06-27 1988-11-28 Richter Gedeon Vegyeszet Process for preparing 2-halogenated ergoline derivatives
GB9218242D0 (en) * 1992-08-27 1992-10-14 Ici Plc Chemical process
JPH11507386A (ja) * 1995-06-07 1999-06-29 エルゴ・サイエンス・インコーポレイテッド 哺乳類における新生物疾患を阻害する方法
CN103073387A (zh) * 2013-02-08 2013-05-01 天津师范大学 一种9,10-二溴蒽的制备方法
CN105646547B (zh) * 2014-12-03 2019-05-17 四川海思科制药有限公司 一种甲磺酸溴隐亭化合物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
CH573431A5 (en) * 1972-06-13 1976-03-15 Sandoz Ag Dibromo-dihydro-lysergic acid prepn. - by bromination of 9,10-dihydro-lysergic acid in inert solvent, pref. glacial alcoholic or propionic acid
DE2330912C3 (de) * 1972-06-22 1979-01-11 Societa Farmaceutici Italia S.P.A., Mailand (Italien) Verfahren zur Herstellung von Bromergolinverbindungen
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
YU216177A (en) * 1977-09-09 1984-02-29 Rudolf Rucman Process for preparing 2-bromo ergosine
US4609731A (en) * 1979-10-10 1986-09-02 Sandoz Ltd. Process for brominating ergot alkaloids
DE3101535A1 (de) * 1981-01-14 1982-08-12 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
DE3340025C2 (de) * 1983-11-03 1986-01-09 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen

Also Published As

Publication number Publication date
ES8707236A1 (es) 1987-07-16
HU193317B (en) 1987-09-28
IT8620761A1 (it) 1987-12-11
IT1191806B (it) 1988-03-23
CS262670B2 (en) 1989-03-14
DE3619617A1 (de) 1986-12-18
ES555932A0 (es) 1987-07-16
YU100886A (en) 1988-04-30
US4697017A (en) 1987-09-29
GB2176479B (en) 1988-12-14
FR2583419A1 (fr) 1986-12-19
GB8614342D0 (en) 1986-07-16
HUT40445A (en) 1986-12-28
GB2176479A (en) 1986-12-31
CH667092A5 (de) 1988-09-15
CS435886A2 (en) 1988-08-16
JPS61286390A (ja) 1986-12-16
BE904897A (fr) 1986-12-10
FR2583419B1 (fr) 1990-01-12
CA1256103A (en) 1989-06-20

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