IT8667183A0 - Derivati di anilina terapeuticamente attivi,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono - Google Patents

Derivati di anilina terapeuticamente attivi,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Info

Publication number
IT8667183A0
IT8667183A0 IT8667183A IT6718386A IT8667183A0 IT 8667183 A0 IT8667183 A0 IT 8667183A0 IT 8667183 A IT8667183 A IT 8667183A IT 6718386 A IT6718386 A IT 6718386A IT 8667183 A0 IT8667183 A0 IT 8667183A0
Authority
IT
Italy
Prior art keywords
therapeuticly
procedure
contain
preparation
pharmaceutical compositions
Prior art date
Application number
IT8667183A
Other languages
English (en)
Other versions
IT1221079B (it
Inventor
Bent Tvaermose Nielsen Ole
Ahnfelt-Ronne Yan
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858506094A external-priority patent/GB8506094D0/en
Priority claimed from GB858525153A external-priority patent/GB8525153D0/en
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of IT8667183A0 publication Critical patent/IT8667183A0/it
Application granted granted Critical
Publication of IT1221079B publication Critical patent/IT1221079B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C07D213/34—Sulfur atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT67183/86A 1985-03-08 1986-03-06 Derivati di anilina terapeuticamente attivi,procedimento per la loro preparazione e composizioni farmaceutiche che il contengono IT1221079B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858506094A GB8506094D0 (en) 1985-03-08 1985-03-08 Chemical products
GB858525153A GB8525153D0 (en) 1985-10-11 1985-10-11 Chemical compounds

Publications (2)

Publication Number Publication Date
IT8667183A0 true IT8667183A0 (it) 1986-03-06
IT1221079B IT1221079B (it) 1990-06-21

Family

ID=26288945

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67183/86A IT1221079B (it) 1985-03-08 1986-03-06 Derivati di anilina terapeuticamente attivi,procedimento per la loro preparazione e composizioni farmaceutiche che il contengono

Country Status (18)

Country Link
US (2) US4826987A (it)
JP (1) JPH0764813B2 (it)
AU (1) AU585586B2 (it)
BE (1) BE904368A (it)
CA (1) CA1276640C (it)
DE (1) DE3607382A1 (it)
DK (1) DK166582B1 (it)
ES (1) ES8802610A1 (it)
FR (1) FR2578540B1 (it)
GB (1) GB2173788B (it)
GR (1) GR860628B (it)
IE (1) IE58870B1 (it)
IT (1) IT1221079B (it)
LU (1) LU86349A1 (it)
NL (1) NL8600596A (it)
NZ (1) NZ215347A (it)
PT (1) PT82147B (it)
SE (1) SE463819B (it)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3682160D1 (de) * 1985-10-16 1991-11-28 Merck Frosst Canada Inc 2-substituierte chinoline.
DK196688A (da) * 1987-04-28 1988-10-29 Fujisawa Pharmaceutical Co Bicykliske forbindelser og fremgangsmaade til fremstilling deraf
US4826990A (en) * 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
GB8728051D0 (en) * 1987-12-01 1988-01-06 Leo Pharm Prod Ltd Chemical compounds
US4889935A (en) * 1987-12-18 1989-12-26 American Home Products Corporation Aminoguanidine derivatives
US5248685A (en) * 1989-04-07 1993-09-28 Pfizer Inc. Substituted 1-[3-(heteroarylmethoxy)phenyl]alkanols and related compounds in the treatment of asthma
DE3927369A1 (de) * 1989-08-19 1991-02-21 Bayer Ag Substituierte n-(chinolin-2-yl-methoxy)benzyl-sulfonyl-harnstoffe
DE3935139A1 (de) * 1989-10-21 1991-04-25 Bayer Ag Substituierte (chinolin-2-yl-methoxy)phenyl-thioharnstoffe
US5021576A (en) * 1989-10-27 1991-06-04 American Home Products Corporation 2-Anilino phenylacetic acid derivatives
US5324747A (en) * 1992-07-15 1994-06-28 Hoffmann-La Roche Inc. N-substituted anilines, inhibitors of phospholipases A2
US5840318A (en) * 1993-05-11 1998-11-24 Immunom Technologies, Inc. Methods and compositions for modulating immune systems of animals
US7189834B2 (en) * 1993-05-11 2007-03-13 Marshall William E Oligoribonucleotides alert the immune system of animals to the imminence of microbial infection
US5508408A (en) * 1993-09-10 1996-04-16 Ciba-Geigy Corporation Quinoline compound
US5795900A (en) * 1995-10-03 1998-08-18 Abbott Laboratories Symmetrical bis-heteroaryl-methoxy-phenylalkyl carboxylates as inhibitors of leukotriene biosynthesis
US5668150A (en) * 1996-07-26 1997-09-16 Abbott Laboratories Non-symmetrical bis-heteroarylmethoxyphenylalkyl carboxylates as inhibitors of leukotriene biosynthesis
US5985856A (en) * 1997-12-31 1999-11-16 University Of Kansas Water soluble prodrugs of secondary and tertiary amine containing drugs and methods of making thereof
HN2001000008A (es) * 2000-01-21 2003-12-11 Inc Agouron Pharmaceuticals Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo
US8399666B2 (en) * 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) * 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) * 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
TW200920369A (en) * 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
CN102137858B (zh) * 2008-05-23 2014-07-23 潘米拉制药有限责任公司 5-脂氧合酶-活化蛋白抑制剂
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
TW201215607A (en) 2010-07-02 2012-04-16 Lundbeck & Co As H Aryl-and heteroarylamid derivatives as PDE10A enzyme inhibitor

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US31624A (en) * 1861-03-05 Tatting-frame
US2761865A (en) * 1954-07-07 1956-09-04 Hoffmann La Roche Pyridylalkyl sulfones
US4003906A (en) * 1974-01-22 1977-01-18 The Dow Chemical Company Substituted pyridinyl methylthio or (methylsulfonyl)benzeneamines
GB2069492B (en) * 1980-02-20 1984-02-29 Wyeth John & Brother Ltd Sulphur compounds
GB2069493B (en) * 1980-02-20 1984-02-29 Wyeth John & Brother Ltd Pyridine derivatives
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
US4567184A (en) * 1982-12-01 1986-01-28 Usv Pharmaceutical Corporation Certain aryl or hetero-aryl derivatives of 1-hydroxy-pentane or 1-hydroxy-hexane which are useful for treating inflammation and allergies
JPS5988835U (ja) * 1982-12-06 1984-06-15 ホシデン株式会社 スイツチ
US4486593A (en) * 1983-01-19 1984-12-04 The Upjohn Company 2-,3-, or 4-Pyridinylmethylamino arylic acids as thromboxane A2 synthetase and 5-lipoxygenase inhibitors
US4563463A (en) * 1983-03-18 1986-01-07 Usv Pharmaceutical Corp. 2-Oxo-1,3-oxazolo[4,5-h] quinolines useful as anti-allergy agents
US4554355A (en) * 1984-07-19 1985-11-19 American Home Products Corporation Heterocyclic compounds as antiallergic agents
US5109009A (en) * 1985-03-08 1992-04-28 Leo Pharmaceutical Products Ltd. Quinoline and pyridine compounds and inhibition of 5-lipoxygenases therewith

Also Published As

Publication number Publication date
IT1221079B (it) 1990-06-21
DK96986A (da) 1986-09-09
NZ215347A (en) 1990-02-26
JPH0764813B2 (ja) 1995-07-12
ES552805A0 (es) 1988-09-16
CA1276640C (en) 1990-11-20
AU5444486A (en) 1986-09-18
FR2578540A1 (fr) 1986-09-12
IE58870B1 (en) 1993-11-17
US5157039A (en) 1992-10-20
AU585586B2 (en) 1989-06-22
PT82147A (en) 1986-04-01
BE904368A (fr) 1986-09-08
FR2578540B1 (fr) 1990-11-16
SE463819B (sv) 1991-01-28
DE3607382A1 (de) 1986-09-11
PT82147B (pt) 1988-07-29
SE8600913D0 (sv) 1986-02-28
DK96986D0 (da) 1986-03-04
ES8802610A1 (es) 1988-09-16
LU86349A1 (fr) 1987-04-02
SE8600913L (sv) 1986-09-09
NL8600596A (nl) 1986-10-01
GR860628B (en) 1986-06-26
DK166582B1 (da) 1993-06-14
JPS61207374A (ja) 1986-09-13
US4826987A (en) 1989-05-02
GB8604183D0 (en) 1986-03-26
IE860370L (en) 1986-09-08
GB2173788B (en) 1988-08-10
GB2173788A (en) 1986-10-22

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960329