IT8667976A0 - Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono - Google Patents

Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono

Info

Publication number
IT8667976A0
IT8667976A0 IT8667976A IT6797686A IT8667976A0 IT 8667976 A0 IT8667976 A0 IT 8667976A0 IT 8667976 A IT8667976 A IT 8667976A IT 6797686 A IT6797686 A IT 6797686A IT 8667976 A0 IT8667976 A0 IT 8667976A0
Authority
IT
Italy
Prior art keywords
theophyllinmethyldithiolane
theophyllinmethyldithiano
preparation
pharmaceutical compositions
derivatives procedure
Prior art date
Application number
IT8667976A
Other languages
English (en)
Other versions
IT1197516B (it
Inventor
Jose Sebastian Franzone
E Sergio De Vercelli
Original Assignee
Abc Ist Biolog Chem Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abc Ist Biolog Chem Spa filed Critical Abc Ist Biolog Chem Spa
Priority to IT67976/86A priority Critical patent/IT1197516B/it
Publication of IT8667976A0 publication Critical patent/IT8667976A0/it
Priority to EP87118646A priority patent/EP0272596B1/en
Priority to DE3789290T priority patent/DE3789290T2/de
Priority to ES87118646T priority patent/ES2061478T3/es
Priority to AT87118646T priority patent/ATE102623T1/de
Priority to CA000555134A priority patent/CA1284996C/en
Priority to JP62326661A priority patent/JP2609458B2/ja
Priority to US07/137,694 priority patent/US4868186A/en
Application granted granted Critical
Publication of IT1197516B publication Critical patent/IT1197516B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT67976/86A 1986-12-24 1986-12-24 Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono IT1197516B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT67976/86A IT1197516B (it) 1986-12-24 1986-12-24 Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
EP87118646A EP0272596B1 (en) 1986-12-24 1987-12-16 Theophyllinemethyldithiolan and theophyllinemethyldithianyl derivates, a method for their preparation and pharmaceutical compositions in which they are included
DE3789290T DE3789290T2 (de) 1986-12-24 1987-12-16 Theophyllinmethyldithiolan und Theophyllinmethyldithianylderivate, ein Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate.
ES87118646T ES2061478T3 (es) 1986-12-24 1987-12-16 Derivados de teofilin-metil-ditiolano y teofilin-metil-ditianilo, un metodo para su preparacion, y composiciones farmaceuticas que los contienen.
AT87118646T ATE102623T1 (de) 1986-12-24 1987-12-16 Theophyllinmethyldithiolan und theophyllinmethyldithianylderivate, ein verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
CA000555134A CA1284996C (en) 1986-12-24 1987-12-22 Theophyllinemethyldithiolan and theophyllinemethyldithianyl derivatives
JP62326661A JP2609458B2 (ja) 1986-12-24 1987-12-23 テオフィリンメチルジチオランおよびテオフィリンメチルジチアニル誘導体
US07/137,694 US4868186A (en) 1986-12-24 1987-12-24 Theophyllinemethyldithiolan and theophyllinemethyldithianyl derivatives having antibronchospastic antitussive and mucolytic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT67976/86A IT1197516B (it) 1986-12-24 1986-12-24 Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono

Publications (2)

Publication Number Publication Date
IT8667976A0 true IT8667976A0 (it) 1986-12-24
IT1197516B IT1197516B (it) 1988-11-30

Family

ID=11306879

Family Applications (1)

Application Number Title Priority Date Filing Date
IT67976/86A IT1197516B (it) 1986-12-24 1986-12-24 Derivati teofillinmetilanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono

Country Status (8)

Country Link
US (1) US4868186A (it)
EP (1) EP0272596B1 (it)
JP (1) JP2609458B2 (it)
AT (1) ATE102623T1 (it)
CA (1) CA1284996C (it)
DE (1) DE3789290T2 (it)
ES (1) ES2061478T3 (it)
IT (1) IT1197516B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8906792D0 (en) 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
HU206884B (en) * 1990-11-22 1993-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing purin derivatives and pharmaceutical compositions containing them
IT1240843B (it) * 1990-05-24 1993-12-17 Malesci Istituto Farmacobiologico Derivati xantinici 1-7 sostituiti ad attivita' antiasmatica, loro sali fisiologicamente accettabili, loro composizioni farmaceutiche e procedimento per la loro preparazione.
IL100088A (en) * 1990-11-21 1995-07-31 Smithkline Beecham Corp FNT inhibitor preparations containing histogenic transducts converted at positions 1, 3, and 8
MX9203323A (es) * 1991-07-11 1994-07-29 Hoechst Ag El empleo de derivados de xantina para el tratamiento de lesiones secundarias de las celulas nerviosas y trastornos funcionales despues de traumas craneo-cerebrales.
US5786360A (en) 1996-11-19 1998-07-28 Link Technology Incorporated A1 adenosine receptor antagonists
EP1601649A4 (en) * 2003-02-19 2009-03-04 Endacea Inc A1-adenosine receptor antagonistic
US7247639B2 (en) * 2003-06-06 2007-07-24 Endacea, Inc. A1 adenosine receptor antagonists
US20090068101A9 (en) * 2003-06-09 2009-03-12 Endacea, Inc. A1 Adenosine Receptor Antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3171778A (en) * 1961-12-07 1965-03-02 Diamond Alkali Co Biologically active applications of hexachloro-trithiane-tetroxide and trimethyl-tritiane-dioxide
DE2330742C2 (de) * 1973-06-16 1982-07-29 Hoechst Ag, 6000 Frankfurt 1-(Oxoalkyl)-3-methyl-7-alkylxanthine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US4109006A (en) * 1976-10-12 1978-08-22 Warren-Teed Laboratories, Inc. 1,4-dithiinoxides
US4309553A (en) * 1977-09-27 1982-01-05 American Cyanamid Company Aldehydes and ketones containing a 4-(monoalkylamino)-benzoyl substituent
IT1113122B (it) * 1978-04-06 1986-01-20 Abc Ist Biolog Chem Spa Composizione farmaceutica ad attivita' antibrocospastica e antitosse
JPS5639091A (en) * 1979-08-24 1981-04-14 Maruko Seiyaku Kk Xanthine derivative
IT1195267B (it) * 1980-04-15 1988-10-12 Abc Ist Biolog Chem Spa Derivati teofillinmetildiossolanici,procedimento per la loro preparazione e relative composizioni farmaceutiche
JPS5711981A (en) * 1980-06-26 1982-01-21 Sagami Chem Res Center Theobromine derivative and its preparation
JPS58134092A (ja) * 1982-02-05 1983-08-10 Sagami Chem Res Center テオブロミン誘導体
JPS5939891A (ja) * 1982-08-27 1984-03-05 Takeda Chem Ind Ltd １，３−ジチアン類、その製造法及び殺虫組成物
DE3574381D1 (en) * 1984-07-27 1989-12-28 Boehringer Biochemia Srl Xanthinylmethylthiazolidines, process for their preparation and pharmaceutical compositions containing them
US4755517A (en) * 1986-07-31 1988-07-05 Warner-Lambert Company Derivatives of xanthine, pharmaceutical compositions and methods of use therefor

Also Published As

Publication number Publication date
IT1197516B (it) 1988-11-30
JP2609458B2 (ja) 1997-05-14
EP0272596B1 (en) 1994-03-09
US4868186A (en) 1989-09-19
DE3789290D1 (de) 1994-04-14
EP0272596A3 (en) 1990-03-28
DE3789290T2 (de) 1994-06-09
EP0272596A2 (en) 1988-06-29
ES2061478T3 (es) 1994-12-16
ATE102623T1 (de) 1994-03-15
CA1284996C (en) 1991-06-18
JPS63233983A (ja) 1988-09-29

Similar Documents

Publication Publication Date Title
IT1224840B (it) Derivati di adenosina, composizioni farmaceutiche che li contengono erelativo procedimento di preparazione ed appplicazione
IT1196048B (it) Derivati della tiazolina,procedimento per la loro preparazione e loro composizioni farmaceutiche
IT8567757A0 (it) Derivati di benzonorbornene procedimento per la loro preparazione e composizioni medicinali e cosmetiche che li contengono
IT8667183A0 (it) Derivati di anilina terapeuticamente attivi,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1224226B (it) Derivati benzofuranici procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che li comprendono
IT1205665B (it) Derivati 1-(idrossistiril)-5h2,3-benzodiazepinici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1196488B (it) Poli-4-aminopirrol-2-carbossamido derivati e procedimento per la loro preparazione
IT1129933B (it) Derivati tioetilammidici loro composizioni farmaceutiche e procedimento per la loro preparazione
IT8667976A0 (it) Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono
IT1177485B (it) Composizioni farmaceutiche antitumorali e procedimento per la loro preparazione
IT1227456B (it) Nuovi alcossi derivati di ginkgolidi, loro preparazione e composizioni terapeutiche che li contengono
IT8248970A0 (it) Derivati xantinici, procedimento per la loro preparazione, composizione farmaceutiche che li contengono e loro impiego terapeutico
IT1193590B (it) Derivati amino-alchil-solfonici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1243203B (it) Derivati aminopropanolici, procedimenti per la loro preparazione e composizioni farmaceutiche che li contengono
IT1201497B (it) Derivati tienopiridinici,procedimento per la loro preparazione e composizioni terapeutiche che li contengono
IT1214726B (it) Derivati di glucosilmoranolina eprocedimento per la loro preparazione
ITMI910846A1 (it) Derivati di flavoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1176986B (it) Derivati della 4 cloro-furo-(3,4-c)piridina,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1196494B (it) Derivati dell'acito cef-3-em-4-carbossilico,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1217342B (it) Derivati piperazinici e procedimento per la loro preparazione
IT1213235B (it) Derivati della [1,3] ossazino [4,3a] isochinolina, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
IT1227920B (it) Derivati diossazocinici, loro preparazione e composizioni che li contengono
IT1203976B (it) Derivati dell'ergolene, composizioni farmaceutiche che li contengono e procedimento per la preparazione dei medesimi
IT8747852A0 (it) Benzammidi sostituite, procedimento per la loro preparazione e composizioni farmaceutiche che le contengono
IT1217192B (it) Tioeteri chinolinici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971231