ITMI20051085A1 - Metodo di purificazione del cefotetan - Google Patents

Metodo di purificazione del cefotetan

Info

Publication number
ITMI20051085A1
ITMI20051085A1 IT001085A ITMI20051085A ITMI20051085A1 IT MI20051085 A1 ITMI20051085 A1 IT MI20051085A1 IT 001085 A IT001085 A IT 001085A IT MI20051085 A ITMI20051085 A IT MI20051085A IT MI20051085 A1 ITMI20051085 A1 IT MI20051085A1
Authority
IT
Italy
Prior art keywords
cefotetan
purification
tautomer
acid
concerns
Prior art date
Application number
IT001085A
Other languages
English (en)
Inventor
Alessandro Donadoni
Maurizio Zenoni
Original Assignee
Acs Dobfar Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acs Dobfar Spa filed Critical Acs Dobfar Spa
Priority to IT001085A priority Critical patent/ITMI20051085A1/it
Priority to US11/410,022 priority patent/US20060281915A1/en
Priority to AT06113454T priority patent/ATE442371T1/de
Priority to KR1020060040021A priority patent/KR20060128633A/ko
Priority to EP06113454A priority patent/EP1734042B1/en
Priority to DE602006009015T priority patent/DE602006009015D1/de
Priority to CN2006100844161A priority patent/CN1876659B/zh
Publication of ITMI20051085A1 publication Critical patent/ITMI20051085A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IT001085A 2005-06-10 2005-06-10 Metodo di purificazione del cefotetan ITMI20051085A1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT001085A ITMI20051085A1 (it) 2005-06-10 2005-06-10 Metodo di purificazione del cefotetan
US11/410,022 US20060281915A1 (en) 2005-06-10 2006-04-25 Acid cefotetan totally solvent-free and method for obtaining same
AT06113454T ATE442371T1 (de) 2005-06-10 2006-05-03 Víllig lísungsmittelfreie cefotetan säure und verfahren zu ihrer herstellung.
KR1020060040021A KR20060128633A (ko) 2005-06-10 2006-05-03 용매가 전혀 존재하지 않는 산 세포테탄 및 이를 수득하는방법
EP06113454A EP1734042B1 (en) 2005-06-10 2006-05-03 Acid cefotetan totally solvent free and method for obtaining same
DE602006009015T DE602006009015D1 (de) 2005-06-10 2006-05-03 ahren zu ihrer Herstellung.
CN2006100844161A CN1876659B (zh) 2005-06-10 2006-05-18 完全没有溶剂的酸头孢替坦和获得它的方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001085A ITMI20051085A1 (it) 2005-06-10 2005-06-10 Metodo di purificazione del cefotetan

Publications (1)

Publication Number Publication Date
ITMI20051085A1 true ITMI20051085A1 (it) 2006-12-11

Family

ID=37102977

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001085A ITMI20051085A1 (it) 2005-06-10 2005-06-10 Metodo di purificazione del cefotetan

Country Status (7)

Country Link
US (1) US20060281915A1 (it)
EP (1) EP1734042B1 (it)
KR (1) KR20060128633A (it)
CN (1) CN1876659B (it)
AT (1) ATE442371T1 (it)
DE (1) DE602006009015D1 (it)
IT (1) ITMI20051085A1 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20051115A1 (it) * 2005-06-14 2006-12-15 Acs Dobfar Spa Procedimento per l'ottenimento di cefotetan con resa elevata
CN101412715B (zh) * 2008-12-16 2010-04-14 海南百那医药发展有限公司 一种氨曲南化合物及其制法
CN101870704B (zh) * 2009-04-21 2012-08-08 扬子江药业集团有限公司 一种头孢替坦酸粗品的纯化方法
CN102250125B (zh) * 2011-05-20 2013-10-16 海南合瑞制药股份有限公司 一种头孢替坦的制备方法
CN103044458A (zh) * 2012-12-25 2013-04-17 深圳华润九新药业有限公司 头孢替坦二钠纯化方法
CN108774247B (zh) * 2018-07-23 2020-10-16 福建省福抗药业股份有限公司 一种头孢替坦酸的制备方法

Family Cites Families (23)

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US2162686A (en) * 1939-01-28 1939-06-13 Henry A Wallace Method for the preparation of thionol
US2841524A (en) * 1955-11-25 1958-07-01 Monsanto Chemicals Adducts of trithiane with sulfenyl chlorides and phosphites
US2956878A (en) * 1956-11-13 1960-10-18 Eastman Kodak Co Photosensitive polymers and their applications in photography
US3852294A (en) * 1968-08-27 1974-12-03 Merck Patent Gmbh Bis-quaternary pyridinium salts
CH648317A5 (de) * 1977-06-10 1985-03-15 Yamanouchi Pharma Co Ltd 7alpha-methoxy-7betha-(1,3-dithietan-2- carboxamido)cephalosporansaeurederivate und verfahren zu ihrer herstellung.
US4285954A (en) * 1980-11-19 1981-08-25 Zoecon Corporation Pesticidal S-pyridyl thioesters of phenylbutanoic acids and derivatives thereof
US4381320A (en) * 1981-06-03 1983-04-26 Johnson & Johnson Non-ionic absorbent polymers
US4785055A (en) * 1986-05-05 1988-11-15 American Cyanamid Company Process for the preparation of N-haloamide polymers
US4868251A (en) * 1986-12-24 1989-09-19 Allergan, Inc. Ultraviolet light absorbing silicone compositions
EP0290136A3 (en) * 1987-03-31 1990-03-14 Yamanouchi Pharmaceutical Co. Ltd. 7-beta-substituted-3-lower alkanoylacetoxymethyl-7-alpha-methoxy-3-cephem-4-carboxylic acid and process for production of same
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
US5061760A (en) * 1990-03-09 1991-10-29 Hoechst Celanese Corporation Vinylidene cyanide alternating copolymers exhibiting nonlinear optical and piezoelectric properties
US5585202A (en) * 1995-04-24 1996-12-17 Eastman Kodak Company Radiographic phosphor panel having organolead reducing agents
US5839258A (en) * 1995-11-28 1998-11-24 Mitsubishi Chemical Corporation Storing method for adsorbent particles
US20010009756A1 (en) * 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
ITMI20010964A1 (it) * 2001-05-10 2002-11-10 Acs Dobfar Spa Procedimento per l'ottenimento di composti utili per la produzione del cefotetan e nuovi composti cosi' ottenuti
US8349819B2 (en) * 2002-10-09 2013-01-08 Dr. Reddy's Laboratories New York, Inc. Steroid extraction process from urine sources
US20060182681A1 (en) * 2004-12-28 2006-08-17 Fortum Oyj Catalytic materials and method for the preparation thereof
ITMI20051115A1 (it) * 2005-06-14 2006-12-15 Acs Dobfar Spa Procedimento per l'ottenimento di cefotetan con resa elevata
WO2007063760A1 (ja) * 2005-11-30 2007-06-07 Mitsubishi Chemical Corporation 有機化合物、電荷輸送材料、電荷輸送材料用組成物および有機電界発光素子
US7619056B2 (en) * 2006-06-02 2009-11-17 New Jersey Institute Of Technology Thermoset epoxy polymers from renewable resources
TW200845991A (en) * 2007-01-12 2008-12-01 Smithkline Beecham Corp N-substituted glycine derivatives: hydroxylase inhibitors
WO2009038157A1 (ja) * 2007-09-21 2009-03-26 Eisai R & D Management Co., Ltd. ２，３－ジヒドロ－イミノイソインドール誘導体

Also Published As

Publication number Publication date
EP1734042A1 (en) 2006-12-20
EP1734042B1 (en) 2009-09-09
CN1876659A (zh) 2006-12-13
CN1876659B (zh) 2010-12-22
DE602006009015D1 (de) 2009-10-22
US20060281915A1 (en) 2006-12-14
ATE442371T1 (de) 2009-09-15
KR20060128633A (ko) 2006-12-14

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