ITRM910189A0 - Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono - Google Patents

Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono

Info

Publication number
ITRM910189A0
ITRM910189A0 IT91RM189A ITRM910189A ITRM910189A0 IT RM910189 A0 ITRM910189 A0 IT RM910189A0 IT 91RM189 A IT91RM189 A IT 91RM189A IT RM910189 A ITRM910189 A IT RM910189A IT RM910189 A0 ITRM910189 A0 IT RM910189A0
Authority
IT
Italy
Prior art keywords
aminoacil
allopurinol
contain
pharmaceutical compositions
immunostimulant activity
Prior art date
Application number
IT91RM189A
Other languages
English (en)
Inventor
Mauro Marzi
Patrizia Minetti
Piero Foresta
Maria Ornella Tinti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM910189A0 publication Critical patent/ITRM910189A0/it
Priority to ITRM910189A priority Critical patent/IT1244501B/it
Priority to ES92830136T priority patent/ES2094335T3/es
Priority to AT92830136T priority patent/ATE143024T1/de
Priority to DE69213794T priority patent/DE69213794T2/de
Priority to EP92830136A priority patent/EP0506628B1/en
Priority to US07/854,916 priority patent/US5272151A/en
Priority to DK92830136.5T priority patent/DK0506628T3/da
Priority to JP4065009A priority patent/JP3067886B2/ja
Publication of ITRM910189A1 publication Critical patent/ITRM910189A1/it
Application granted granted Critical
Publication of IT1244501B publication Critical patent/IT1244501B/it
Priority to GR960402931T priority patent/GR3021556T3/el
Priority to HK98105617.5A priority patent/HK1006462B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ITRM910189A 1991-03-22 1991-03-22 Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono IT1244501B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ITRM910189A IT1244501B (it) 1991-03-22 1991-03-22 Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono
EP92830136A EP0506628B1 (en) 1991-03-22 1992-03-20 Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharmaceutical formulations containing these substances
AT92830136T ATE143024T1 (de) 1991-03-22 1992-03-20 Aminoacyl und oligopeptidylderivate von allopurinol mit immunostimulierender wirkung und diese enthaltende pharmazeutische zubereitungen
DE69213794T DE69213794T2 (de) 1991-03-22 1992-03-20 Aminoacyl und Oligopeptidylderivate von Allopurinol mit immunostimulierender Wirkung und diese enthaltende pharmazeutische Zubereitungen
ES92830136T ES2094335T3 (es) 1991-03-22 1992-03-20 Derivados de alopurinol aminoacilados y oligopeptidos de actividad inmunoestimuladora y composiciones farmaceuticas que los contienen.
US07/854,916 US5272151A (en) 1991-03-22 1992-03-20 Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharmaceutical formulations containing these substances
DK92830136.5T DK0506628T3 (da) 1991-03-22 1992-03-20 Aminoacyl- og oligopeptidylderivater af allopurinol, der udviser immunostimulerende aktivitet, og farmaceutiske formuleringer indeholdende disse stoffer
JP4065009A JP3067886B2 (ja) 1991-03-22 1992-03-23 アロプリノール誘導体および医薬製剤
GR960402931T GR3021556T3 (en) 1991-03-22 1996-11-06 Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharmaceutical formulations containing these substances
HK98105617.5A HK1006462B (en) 1991-03-22 1998-06-18 Aminoacyl and oligopeptidyl derivatives of allopurinol exhibiting immunostimulatory activity, and pharma-ceutical formulations containing these substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM910189A IT1244501B (it) 1991-03-22 1991-03-22 Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono

Publications (3)

Publication Number Publication Date
ITRM910189A0 true ITRM910189A0 (it) 1991-03-22
ITRM910189A1 ITRM910189A1 (it) 1992-09-22
IT1244501B IT1244501B (it) 1994-07-15

Family

ID=11399991

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM910189A IT1244501B (it) 1991-03-22 1991-03-22 Derivati amminoacilici e oligopeptidici dell'allopurinolo dotati di attivita' immunostimolante e composizioni farmaceutiche che li contengono

Country Status (9)

Country Link
US (1) US5272151A (it)
EP (1) EP0506628B1 (it)
JP (1) JP3067886B2 (it)
AT (1) ATE143024T1 (it)
DE (1) DE69213794T2 (it)
DK (1) DK0506628T3 (it)
ES (1) ES2094335T3 (it)
GR (1) GR3021556T3 (it)
IT (1) IT1244501B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5928191A (en) * 1993-07-30 1999-07-27 E.P. Technologies, Inc. Variable curve electrophysiology catheter
US6110923A (en) * 1994-06-22 2000-08-29 Biochem Pharma Inc. Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity
AU1520699A (en) 1997-11-07 1999-05-31 Johns Hopkins University, The Methods for treatment of disorders of cardiac contractility
CA2340214C (en) 1998-08-12 2007-10-30 Triangle Pharmaceuticals, Inc. Method of manufacture of 1,3-oxathiolane nucleosides
ATE383355T1 (de) * 2001-03-01 2008-01-15 Abbott Lab Polymorph und andere kristallinische formen von zusammen-ftc
WO2003051298A2 (en) * 2001-12-14 2003-06-26 Pharmasset Ltd. Preparation of intermediates useful in the synthesis of antiviral nucleosides
MXPA05001451A (es) 2002-08-06 2005-09-30 Pharmasset Ltd Procesos para preparar nucleosidos de 1,3-dioxolano.
US6953041B2 (en) * 2002-10-09 2005-10-11 Micell Technologies, Inc. Compositions of transition metal species in dense phase carbon dioxide and methods of use thereof
WO2005066694A2 (en) * 2003-12-29 2005-07-21 Advanced Medical Optics, Inc. Intraocular lenses having a visible light-selective-transmissive-region
US7067659B2 (en) * 2004-04-23 2006-06-27 Duke University Reactive oxygen generating enzyme inhibitor with nitric oxide bioactivity and uses thereof
CA2564921C (en) 2004-04-30 2015-03-24 Advanced Medical Optics, Inc. Ophthalmic devices having a highly selective violet light transmissive filter and related methods
AU2005309835B2 (en) * 2004-11-22 2011-08-04 Johnson & Johnson Surgical Vision, Inc. Copolymerizable azo compounds and articles containing them
ATE525664T1 (de) 2004-11-22 2011-10-15 Abbott Medical Optics Inc Copolymerisierbare methin- und anthrachinon- verbindungen und artikel damit
US8188098B2 (en) * 2008-05-19 2012-05-29 Hoffmann-La Roche Inc. GPR119 receptor agonists
US11406713B2 (en) * 2013-03-15 2022-08-09 Xortx Therapeutics, Inc. Xanthine oxidase inhibitor formulations

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3165520A (en) * 1965-01-12 Certificate of correction
AU564576B2 (en) * 1981-09-24 1987-08-20 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Purine derivatives
US4602089A (en) * 1982-03-12 1986-07-22 Newport Pharmaceuticals, Inc. Process for preparing purine compounds
DK302883D0 (da) * 1983-06-30 1983-06-30 Hans Bundgaard Allopurinol prodrugs
US4663326A (en) * 1985-04-04 1987-05-05 Warner-Lambert Company Pyrazolo[4,3-d]pyrimidine-5,7-(4H,6H)dione or -5-thione-7-one analogs
AU611648B2 (en) * 1986-08-11 1991-06-20 Baxter International Inc. Pivot pin bearing/seal with loose eyelet especially suited for disposable continuous flow blood filtration system cartridges
IT1213495B (it) * 1986-09-17 1989-12-20 Sigma Tau Ind Farmaceuti Processo per la preparazione dell'alfa-n-[(ipoxatin-9-il)pentilossicarbonil-]arginina

Also Published As

Publication number Publication date
GR3021556T3 (en) 1997-02-28
EP0506628B1 (en) 1996-09-18
HK1006462A1 (en) 1999-02-26
ATE143024T1 (de) 1996-10-15
DE69213794D1 (de) 1996-10-24
EP0506628A3 (en) 1992-10-21
JP3067886B2 (ja) 2000-07-24
ITRM910189A1 (it) 1992-09-22
US5272151A (en) 1993-12-21
EP0506628A2 (en) 1992-09-30
JPH05117275A (ja) 1993-05-14
ES2094335T3 (es) 1997-01-16
IT1244501B (it) 1994-07-15
DE69213794T2 (de) 1997-02-06
DK0506628T3 (da) 1996-11-11

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19950131