ITTO980264A1 - Applicazione di un estratto basico non quaternario della peschiera fuchsiaefolia ad attivita' antimalarica - Google Patents

Applicazione di un estratto basico non quaternario della peschiera fuchsiaefolia ad attivita' antimalarica Download PDF

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Publication number
ITTO980264A1
ITTO980264A1 IT98TO000264A ITTO980264A ITTO980264A1 IT TO980264 A1 ITTO980264 A1 IT TO980264A1 IT 98TO000264 A IT98TO000264 A IT 98TO000264A IT TO980264 A ITTO980264 A IT TO980264A IT TO980264 A1 ITTO980264 A1 IT TO980264A1
Authority
IT
Italy
Prior art keywords
peschiera
activity
application
fuchsiaefolia
malarica
Prior art date
Application number
IT98TO000264A
Other languages
English (en)
Inventor
Silvio Rossi
Motta Giuseppe Bertelli
Original Assignee
Silvio Rossi
Motta Giuseppe Bertelli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Silvio Rossi, Motta Giuseppe Bertelli filed Critical Silvio Rossi
Priority to IT98TO000264A priority Critical patent/ITTO980264A1/it
Priority to PCT/IB1999/000524 priority patent/WO1999048501A1/fr
Priority to JP2000537549A priority patent/JP2002507570A/ja
Priority to EP99907808A priority patent/EP1067938A1/fr
Priority to APAP/P/2000/001926A priority patent/AP2000001926A0/en
Priority to CA002325879A priority patent/CA2325879A1/fr
Priority to BR9909153-4A priority patent/BR9909153A/pt
Priority to AU27427/99A priority patent/AU2742799A/en
Publication of ITTO980264A1 publication Critical patent/ITTO980264A1/it
Priority to OA1200000261A priority patent/OA11491A/en
Priority to ZA200006020A priority patent/ZA200006020B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Compounds Of Unknown Constitution (AREA)

Description

Applicazione di un estratto basico non quaternario dalla PESCHIERA Fuchsiaefolia ad attività antimala=
rica;
La presente invenzione ha per oggetto l'applicazione dell'estratto basico non quaternario della Pianta
calssifinata con il nome botanico Peschiera Fuchsiae folia, raccolta in Brasile. Porto Alegre Rio do SouL ed identificata dalle Cibecol Industria Farmaceutica La corteccia della Peschiera F. è stata fatta perveni—
re dai fiduciari
effettuarne l’estrazione dei principi attivi denominati Alcaloidi terziari.
sono eluiti nell'ordine la PEVERINA
(pu= rificati per ulteriore separazione per DCC a riciclo e poi l'AFFINISINA. sono eluiti
e la rificati per DCC a riciclo, e successivamente a pH3,2 sono eluiti La VOACALOTIKA e la VOACAMINA
purificati per riciclo. sono stati separati anche per successivo riciclo la CONOFARINGINA (2.10 ) la CORONARIDINA e la VOACANGI S
MA
L'insieme di questi alcaloidi così ottenuti sono stati inviati all'Organizzazione Mondiale di Sanità D.M.S. per le prove in vitro sul Plasmodium Palcipa
rum(l 'agente» patogeno della malaria) per le prove di laboratorio .
T dati risultanti da queste prove sono la comprova dell 'attività antimalarica dell'estratto, dimostrato dal commento dello screener "YESYES".

Claims (1)

  1. RIVENDICAZIONI Si rivendica che l'estratto ottenuto con la metodo= logia descritta,ha efficacia sul Plasmodium Falcipa= rum e quindi usato puro o diluito nelle percentuali, descritte ed esemplificate nell'allegata documenta zione sia nella forma liquida per uso orale, sotto= cutanea, parenterale, per inalazione, per osmosi, per diluizione omeopatica, sia nella forma solida, per uso orale per inalazione, osmosi, ed in forma Omeopatica. venga tutelato dal presente atto. 1' efficacia dell' estratto secondo la rivendicazione I ha effetto sia per la profilassi che per la cura della malaria.
IT98TO000264A 1998-03-26 1998-03-26 Applicazione di un estratto basico non quaternario della peschiera fuchsiaefolia ad attivita' antimalarica ITTO980264A1 (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT98TO000264A ITTO980264A1 (it) 1998-03-26 1998-03-26 Applicazione di un estratto basico non quaternario della peschiera fuchsiaefolia ad attivita' antimalarica
PCT/IB1999/000524 WO1999048501A1 (fr) 1998-03-26 1999-03-25 Voacamine en tant qu'agent anti-paludeen et agent anti-paludeen contenant de la voacamine
JP2000537549A JP2002507570A (ja) 1998-03-26 1999-03-25 抗マラリア剤としてのボーカミン及びボーカミンを含有する抗マラリア剤
EP99907808A EP1067938A1 (fr) 1998-03-26 1999-03-25 Voacamine en tant qu'agent anti-paludeen et agent anti-paludeen contenant de la voacamine
APAP/P/2000/001926A AP2000001926A0 (en) 1998-03-26 1999-03-25 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine.
CA002325879A CA2325879A1 (fr) 1998-03-26 1999-03-25 Voacamine en tant qu'agent anti-paludeen et agent anti-paludeen contenant de la voacamine
BR9909153-4A BR9909153A (pt) 1998-03-26 1999-03-25 Voacamina como um agente antimalária, e agente antimalária que contém voacamina
AU27427/99A AU2742799A (en) 1998-03-26 1999-03-25 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine
OA1200000261A OA11491A (en) 1998-03-26 2000-09-22 Voacamine as anti-malarial agent and anti-malarialagent containing voacamine.
ZA200006020A ZA200006020B (en) 1998-03-26 2000-10-26 Voacamine as anti-malarial agent and anti-malarial agent containing voacamine.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT98TO000264A ITTO980264A1 (it) 1998-03-26 1998-03-26 Applicazione di un estratto basico non quaternario della peschiera fuchsiaefolia ad attivita' antimalarica

Publications (1)

Publication Number Publication Date
ITTO980264A1 true ITTO980264A1 (it) 1999-09-26

Family

ID=11416637

Family Applications (1)

Application Number Title Priority Date Filing Date
IT98TO000264A ITTO980264A1 (it) 1998-03-26 1998-03-26 Applicazione di un estratto basico non quaternario della peschiera fuchsiaefolia ad attivita' antimalarica

Country Status (10)

Country Link
EP (1) EP1067938A1 (it)
JP (1) JP2002507570A (it)
AP (1) AP2000001926A0 (it)
AU (1) AU2742799A (it)
BR (1) BR9909153A (it)
CA (1) CA2325879A1 (it)
IT (1) ITTO980264A1 (it)
OA (1) OA11491A (it)
WO (1) WO1999048501A1 (it)
ZA (1) ZA200006020B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812199A1 (fr) * 2000-07-31 2002-02-01 Maximun Frederic Yanze Nouvelles compositions pharmaceutiques effervescentes contenant la chloroquine
EP1491197A1 (fr) * 2003-06-26 2004-12-29 Bertelli Motta, Guiseppe Composition pharmaceutique à base de voacamine pour la stimulation et modulation du système immunitaire humain
US20070232588A1 (en) * 2004-09-15 2007-10-04 Leonard Stella Anti-parasitic and/or anti-viral and/or anti-microbial compositions
US20070032460A1 (en) * 2005-08-04 2007-02-08 Leonard Stella Use of voacamine and related compounds in the treatment of malaria
WO2007039915A1 (en) 2005-10-04 2007-04-12 The Director General, Defence Research And Development Organisation Anti-malarial compound isolated from gomphostema niveum
EP1958638A1 (en) 2007-02-14 2008-08-20 Polichem S.A. Use of chitosans to increase nail growth rate
US20140303148A1 (en) * 2011-11-28 2014-10-09 Industry-Academic Cooperation Foundation, Yonsei University Pharmaceutical compositions for inhibiting angiogenesis comprising plant-derived natural compound
CA2896133A1 (en) * 2012-12-20 2014-06-26 Demerx, Inc. Substituted noribogaine
US12459965B2 (en) 2017-10-09 2025-11-04 Compass Pathfinder Limited Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
JP2022529781A (ja) 2019-04-17 2022-06-24 コンパス パスファインダー リミテッド サイロシビンによるうつ病及び他の様々な障害の治療

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2823204A (en) * 1956-03-30 1958-02-11 Gobey Lab Alkaloids of voacanga

Also Published As

Publication number Publication date
ZA200006020B (en) 2001-06-25
JP2002507570A (ja) 2002-03-12
WO1999048501A9 (fr) 2000-03-16
EP1067938A1 (fr) 2001-01-17
WO1999048501A1 (fr) 1999-09-30
AU2742799A (en) 1999-10-18
BR9909153A (pt) 2000-11-14
AP2000001926A0 (en) 2000-09-30
CA2325879A1 (fr) 1999-09-30
OA11491A (en) 2004-05-07

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