JO3286B1 - متراكبات مائية من حديد و كربوهيدرات,انتاجها و ادوية تحتوي عليها - Google Patents
متراكبات مائية من حديد و كربوهيدرات,انتاجها و ادوية تحتوي عليهاInfo
- Publication number
- JO3286B1 JO3286B1 JOP/2003/0130A JOP20030130A JO3286B1 JO 3286 B1 JO3286 B1 JO 3286B1 JO P20030130 A JOP20030130 A JO P20030130A JO 3286 B1 JO3286 B1 JO 3286B1
- Authority
- JO
- Jordan
- Prior art keywords
- production
- medicaments containing
- iron carbohydrate
- aqueous iron
- carbohydrate complexes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B31/00—Preparation of derivatives of starch
- C08B31/18—Oxidised starch
- C08B31/185—Derivatives of oxidised starch, e.g. crosslinked oxidised starch
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Abstract
يتعلق الاختراع الراهن بمتراكب قابل للذوبان في الماء من حديد وكربوهيدرات يمكن الحصول عليه من محلول مائي لملح الحديد( III) ومحلول مائي للمنتج الناتج عن اكسدة مركب مالتودكسترون واحد او اكثر له مكافيء دكستروز يتراوح من 5 الى 22 باستخدام محلول هيبوكلوريت مائي عند درجة حموضة تتراوح من 8.5 الى 12 ويتعلق الاختراع الراهن بعملية لانتاجه وبدواء لمعالجة حالات مرضية ناشئة عن نقص الحديد.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10249552A DE10249552A1 (de) | 2002-10-23 | 2002-10-23 | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JO3286B1 true JO3286B1 (ar) | 2018-09-16 |
Family
ID=32102937
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2003/0130A JO3286B1 (ar) | 2002-10-23 | 2003-10-02 | متراكبات مائية من حديد و كربوهيدرات,انتاجها و ادوية تحتوي عليها |
| JOP/2011/0173A JOP20110173B1 (ar) | 2002-10-23 | 2011-05-26 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
| JOP/2018/0046A JOP20180046B1 (ar) | 2002-10-23 | 2018-05-02 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JOP/2011/0173A JOP20110173B1 (ar) | 2002-10-23 | 2011-05-26 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
| JOP/2018/0046A JOP20180046B1 (ar) | 2002-10-23 | 2018-05-02 | متراكبات قابلة للذوبان في الماء من حديد وكربوهيدرات، إنتاجها وأدوية تحتوي عليها |
Country Status (29)
| Country | Link |
|---|---|
| US (11) | US7612109B2 (ar) |
| EP (2) | EP1554315B1 (ar) |
| JP (2) | JP4777653B2 (ar) |
| KR (1) | KR100992178B1 (ar) |
| CN (1) | CN100480275C (ar) |
| AR (1) | AR041472A1 (ar) |
| AT (1) | ATE507246T1 (ar) |
| AU (1) | AU2003278111C1 (ar) |
| BR (2) | BRPI0315452B8 (ar) |
| CA (1) | CA2493806C (ar) |
| CY (2) | CY1112680T1 (ar) |
| DE (2) | DE10249552A1 (ar) |
| DK (2) | DK1554315T3 (ar) |
| ES (2) | ES2364136T3 (ar) |
| IL (1) | IL166747A (ar) |
| JO (3) | JO3286B1 (ar) |
| MX (1) | MXPA05004300A (ar) |
| MY (1) | MY134394A (ar) |
| NO (2) | NO333008B1 (ar) |
| NZ (1) | NZ539243A (ar) |
| PE (1) | PE20040571A1 (ar) |
| PT (2) | PT2287204E (ar) |
| RU (1) | RU2303039C2 (ar) |
| SA (1) | SA03240447B1 (ar) |
| SI (2) | SI1554315T1 (ar) |
| TW (1) | TWI265028B (ar) |
| UY (1) | UY28033A1 (ar) |
| WO (1) | WO2004037865A1 (ar) |
| ZA (1) | ZA200504174B (ar) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6757848B2 (en) | 2001-06-19 | 2004-06-29 | Hewlett-Packard Development Company, L.P. | Recovery of user data from partially incorrect data set in tape data storage system |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| DE102004031181A1 (de) * | 2004-06-28 | 2006-01-19 | Vifor (International) Ag | Phosphatadsorbens |
| MX2007009588A (es) * | 2005-02-09 | 2007-09-12 | Vifor Int Ag | Uso de compuestos de complejo de hierro(iii). |
| ITMO20050056A1 (it) | 2005-03-15 | 2006-09-16 | Biofer Spa | Processo per la preparazione di complessi del ferro trivalente con zuccheri mono-, di- e polisaccaridi. |
| EP1757299A1 (de) * | 2005-08-25 | 2007-02-28 | Vifor (International) Ag | Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung |
| EP1790356A1 (de) * | 2005-11-24 | 2007-05-30 | Vifor (International) Ag | Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en) |
| AU2016205002C1 (en) * | 2006-01-06 | 2020-09-24 | Vifor (International) Ag | Methods and compositions for administration of iron |
| AU2013206429B2 (en) * | 2006-01-06 | 2016-04-28 | Vifor (International) Ag | Methods and compositions for administration of iron |
| PT1973549T (pt) * | 2006-01-06 | 2016-10-25 | Luitpold Pharm Inc | Métodos e composições para administração de ferro |
| EP1941869A1 (en) * | 2007-01-04 | 2008-07-09 | Vifor (International) Ag | Multicompartment bag for storage of iron preparations |
| EP1947120A1 (de) * | 2007-01-19 | 2008-07-23 | Vifor (International) Ag | Eisen-Kohlenhydrat-Komplex-Verbindungen |
| JP5756598B2 (ja) * | 2007-02-06 | 2015-07-29 | メディカル リサーチ カウンシル | リガンド修飾ポリオキソヒドロキシ金属イオン物質、それらの使用およびそれらの調製方法 |
| EP1997833A1 (de) * | 2007-05-29 | 2008-12-03 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| LT3156075T (lt) | 2009-03-25 | 2021-01-11 | Pharmacosmos Holding A/S | Oligosacharidas ir jo paruošimo būdas |
| EP2496595A2 (en) * | 2009-11-04 | 2012-09-12 | Symed Labs Limited | Process for the preparation of iron (iii) carboxymaltose complex |
| US9394324B2 (en) | 2010-03-23 | 2016-07-19 | Vifor (International) Ag | Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias |
| WO2012104204A1 (en) | 2011-01-31 | 2012-08-09 | Vifor (International) Ag | Iron-carbohydrate complex compounds for the intravenous therapy of malaria |
| US9370202B2 (en) | 2013-03-15 | 2016-06-21 | LG Bionano, LLC | Encapsulated metal ion nanoclusters |
| US9384629B2 (en) | 2014-03-31 | 2016-07-05 | Fresh Idea Global Limited | Automated money laundering detection, notification, and reporting techniques implemented at casino gaming networks |
| EP3157516A4 (en) | 2014-06-22 | 2017-12-13 | Dexcel Pharma Technologies Ltd. | Pharmaceutical compositions comprising ferric citrate and methods for the production thereof |
| EP2997968A1 (en) | 2014-09-22 | 2016-03-23 | Ioulia Tseti | Iron (III) hydroxide complexes with activated glucose syrups and process for preparing same |
| CN104402984B (zh) * | 2014-11-11 | 2018-09-07 | 武汉科福新药有限责任公司 | 一种高载铁量的蛋白琥珀酸铁的制备方法 |
| CN107438626A (zh) * | 2015-03-23 | 2017-12-05 | 苏文生命科学有限公司 | 水溶性三价铁碳水化合物复合物的制备 |
| WO2016181195A1 (en) | 2015-05-08 | 2016-11-17 | Suven Life Sciences Limited | Improved process for water soluble iron carbohydrate complexes |
| WO2016196274A1 (en) * | 2015-05-29 | 2016-12-08 | Luitpold Pharmaceuticals, Inc. | Compositions and methods for treatment of fibromyalgia |
| CN105125577B (zh) * | 2015-07-29 | 2018-05-18 | 南京生命能科技开发有限公司 | 一种稳定的糖-铁复合物及其制备方法 |
| CN105125578B (zh) * | 2015-07-29 | 2018-05-11 | 南京生命能科技开发有限公司 | 一种具有高溶解速度的糖-铁复合物及其制备方法 |
| US10258647B2 (en) | 2015-09-01 | 2019-04-16 | Particle Dynamics International, Llc | Iron-polysaccharide complexes and methods for the preparation thereof |
| GB201517893D0 (en) | 2015-10-09 | 2015-11-25 | Medical Res Council | Methods for producing carboxylate ligand modified ferric iron hydroxide colloids |
| CN105520955B (zh) * | 2015-12-21 | 2018-05-11 | 南京生命能科技开发有限公司 | 一种羧基麦芽糖铁药用组合物及其制备方法 |
| CN108129582A (zh) * | 2016-12-01 | 2018-06-08 | 江苏奥赛康药业股份有限公司 | 一种铁碳水化合物复合物的制备方法 |
| EP3339329A1 (en) | 2016-12-22 | 2018-06-27 | LEK Pharmaceuticals d.d. | Selective oxidation of maltodextrin and its use in the preparation of water-soluble iron (iii) carboxymaltose complexes |
| AU2018328052C1 (en) | 2017-09-11 | 2025-12-18 | Pharmacosmos Holding A/S | Iron complex compounds for therapeutic use |
| US20210155651A1 (en) * | 2018-04-05 | 2021-05-27 | Msn Laboratories Private Limited, R&D Center | Process for the preparation of iron (iii) carboxymaltose |
| CN108498539A (zh) * | 2018-05-03 | 2018-09-07 | 东营天东制药有限公司 | 一种水溶性铁剂复合体原料药的制备方法 |
| MX2021004640A (es) | 2018-10-29 | 2021-05-28 | Pharmacosmos Holding As | Tratamiento de la deficiencia de hierro con carboximaltosa ferrica. |
| EP3897661A1 (en) | 2018-12-21 | 2021-10-27 | Vifor (International) Ag | Ferric carboxymaltose in the treatment of heart failure and in the treatment of congestion in heart failure |
| CN110218267B (zh) * | 2019-07-04 | 2020-08-07 | 汉邦环宇多糖生物科技(河源)有限公司 | 一种右旋糖酐铁的制备方法及用途 |
| US11447513B2 (en) * | 2020-02-12 | 2022-09-20 | Rk Pharma Inc. | Purification process of ferric carboxymaltose |
| GB202005054D0 (en) | 2020-04-06 | 2020-05-20 | Nemysis Ltd | Carboxylate Ligand Modified Ferric Iron Hydroxide Compositions for Use in the Treatment or Prevention of Iron Deficiency Associated with Liver Diseases |
| EP4221723A4 (en) * | 2020-09-29 | 2024-11-06 | LG Bionano, LLC | PROCESSES FOR PREPARATION OF IRON-BASED COMPLEXES |
| TWI784646B (zh) | 2021-07-29 | 2022-11-21 | 台耀化學股份有限公司 | 製備羧基麥芽糖鐵的方法 |
| EP4392045A1 (en) | 2021-08-27 | 2024-07-03 | American Regent, Inc. | Iron compositions and methods of making and using them |
| WO2023041957A1 (en) * | 2021-09-16 | 2023-03-23 | Virchow Biotech Private Limited | Efficient process for the synthesis of iron (iii) carbohydrate complexes |
| WO2024069644A1 (en) * | 2022-09-30 | 2024-04-04 | West Bengal Chemical Industries Limited | A pharmaceutically acceptable ferric carboxymaltose and preparation thereof |
| WO2026017897A1 (en) | 2024-07-18 | 2026-01-22 | Malian Biologicals Gmbh | Iron supplementation in affective disorders and/or post-traumatic stress disorder (ptsd) and/or serotonin-dependent diseases |
Family Cites Families (115)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE370194C (de) | 1923-02-28 | Therese Rocksch Geb Laschet | Elektrolytisches Zinnbad zur Darstellung schwammfreier Zinnkristalle | |
| CA623411A (en) | 1961-07-04 | Muller Arthur | Process for the manufacture of iron-polyisomaltose complex for therapeutical purposes | |
| US1129307A (en) * | 1914-12-26 | 1915-02-23 | Howard L Marsh | Process of forming compounds of iron and carbohydrates. |
| GB199951A (en) | 1922-07-07 | 1923-07-05 | William Swann | Improvements in or relating to clamps or fastening devices for the brake chains of perambulators, and the like |
| DE461370C (de) | 1925-06-13 | 1928-06-21 | Chem Fab Vormals Sandoz | Verfahren zur Herstellung von Monocarbonsaeuren aus Aldosen |
| GB289280A (en) | 1927-06-17 | 1928-04-26 | Chem Fab Vormals Sandoz | Process for the oxidation of aldoses |
| GB335965A (en) | 1929-06-05 | 1930-10-06 | Ig Farbenindustrie Ag | Process for the manufacture of complex iron compounds |
| US2807610A (en) | 1952-02-15 | 1957-09-24 | Baker Chem Co J T | Hydrogenated dextran |
| GB748024A (en) | 1953-02-27 | 1956-04-18 | Benger S Ltd | Improved therapeutic preparations of iron |
| GB828404A (en) * | 1958-05-07 | 1960-02-17 | Chugai Pharmaceutical Co Ltd | A process for preparing divalent or trivalent metallic salts of glucuronic acid |
| GB879441A (en) | 1959-05-25 | 1961-10-11 | Crookes Lab Ltd | Improved injectable iron preparations |
| US3065138A (en) | 1959-10-09 | 1962-11-20 | Warren Teed Products Company | Therapeutic preparations of elemental iron |
| GB928238A (en) | 1960-01-14 | 1963-06-12 | Diamond Lab Inc | Methods of preparing therapeutic preparations of iron |
| US3100202A (en) | 1960-06-17 | 1963-08-06 | Muller Arthur | Process for preparing an iron hydroxide polyisomaltose complex and the resulting product |
| US3086009A (en) * | 1960-07-19 | 1963-04-16 | Diamond Lab Inc | Process for preparing a water soluble hydrolyzed starch-ferric iron complex |
| GB978485A (en) | 1960-10-26 | 1964-12-23 | Astra Apotekarnes Kem Fab | Iron preparations for intramuscular injection |
| GB928236A (en) | 1960-11-22 | 1963-06-12 | Atomic Energy Authority Uk | Improvements in or relating to organic liquid moderated and cooled nuclear reactors |
| US3151107A (en) | 1960-12-22 | 1964-09-29 | Central Pharmacal Company | Water-soluble iron complexes of carboxymethyl dextran |
| US3076798A (en) * | 1961-02-23 | 1963-02-05 | Hausmann Lab Ltd | Process for preparing a ferric hydroxide polymaltose complex |
| GB985206A (en) | 1961-12-20 | 1965-03-03 | Hausmann Ag Labor | Improvements in or relating to therapeutic iron preparation |
| ES282099A1 (es) | 1962-11-02 | 1963-01-01 | Rocador Sa | Procedimiento para la preparación de un complejo de óxido de hierro y ácidos dextránicos |
| BE652508A (ar) * | 1963-08-30 | |||
| FR1451203A (fr) | 1964-01-31 | 1966-01-07 | Rocador Sa | Procédé pour la fabrication d'un complexe d'oxyde ferrique et de polysaccharide |
| DE1617463A1 (de) * | 1965-11-20 | 1971-04-08 | Bayer Ag | Verfahren zur Herstellung von injizierbaren kolloidalen Eisenzubereitungen |
| US3639588A (en) | 1966-10-22 | 1972-02-01 | Fisons Pharmaceuticals Ltd | Pharmaceutical compositions containing ferric hydroxide complexed with dextran or dextrin heptonic acids |
| GB1183940A (en) | 1966-10-22 | 1970-03-11 | Fisons Pharmaceuticals Ltd | Ferric Hydroxide Complexes |
| SE322866B (ar) * | 1966-12-15 | 1970-04-20 | Astra Ab | |
| GB1199951A (en) | 1967-05-13 | 1970-07-22 | Fisons Pharmaceuticals Ltd | Modified Dextran and Derivatives Thereof |
| GB1200902A (en) * | 1967-05-13 | 1970-08-05 | Fisons Pharmaceuticals Ltd | Iron-dextran complexes |
| US3395229A (en) | 1967-07-03 | 1968-07-30 | Mattox And Moore Inc | Process and product for combatting iron deficiency anemia in suckling pigs |
| AT279048B (de) * | 1967-07-04 | 1970-02-25 | Pharmazeutische Fabrik Montavit Gmbh | Verfahren zur Herstellung neuer, löslicher und stabiler organischer Eisen(III)-Komplexverbindungen und Injektionslösungen davon |
| GB1258566A (ar) | 1968-07-12 | 1971-12-30 | ||
| US3908004A (en) * | 1970-05-20 | 1975-09-23 | C L Basingstoke Limited | Process for making injectable iron compositions for treating iron-deficiency anemia |
| US3821192A (en) | 1971-08-18 | 1974-06-28 | Central Pharmacal Co | Process for preparing an iron-saccharide complex |
| SE359447B (ar) | 1971-10-06 | 1973-09-03 | Astra Laekemedel Ab | |
| US3928581A (en) | 1972-09-13 | 1975-12-23 | Astra Laekemedel Ab | Certain polymer-iron complexes for treatment of iron deficiency |
| US3965133A (en) | 1972-10-04 | 1976-06-22 | Astra Lakemedel Aktiebolag | Polymer |
| US3969395A (en) | 1972-10-04 | 1976-07-13 | Astra Lakemedel Aktiebolag | Polymers of hydroxy carboxylic acid and a polyhydric alcohol |
| US4056672A (en) | 1973-03-22 | 1977-11-01 | Astra Lakemedel Aktiebolag | Polymer prepared by cyanhydrin method |
| JPS6039681B2 (ja) | 1976-01-01 | 1985-09-07 | 日本臓器製薬株式会社 | デキストリン・クエン酸・第二鉄多核複合体及び該複合体を含有する非経口用鉄剤 |
| US4180567A (en) * | 1977-09-02 | 1979-12-25 | Pharmachem Corporation | Iron preparations and methods of making and administering the same |
| US4370476A (en) | 1979-07-17 | 1983-01-25 | Usher Thomas C | Dextran polycarboxylic acids, ferric hydroxide complexes |
| DE3026868C2 (de) * | 1980-07-16 | 1986-03-13 | Laboratorien Hausmann AG, St. Gallen | Verfahren zur Herstellung von Eisen(III)hydroxid-Dextran-Komplexen und sie enthaltende pharmazeutische sterile wäßrige Lösung |
| US4335116A (en) | 1980-10-07 | 1982-06-15 | University Patents, Inc. | Mineral-containing therapeutic compositions |
| EP0051707A1 (en) | 1980-11-12 | 1982-05-19 | Thomas Clemens Usher | Dextran polycarboxylic acids, ferric hydroxide complexes thereof, pharmaceutical compositions containing them and methods for their manufacture |
| DE3114699A1 (de) | 1981-04-10 | 1982-10-28 | Siemens AG, 1000 Berlin und 8000 München | Vorrichtung zum messen der roentgenroehrenhochspannung |
| HU187167B (en) | 1982-10-15 | 1985-11-28 | Richter Gedeon Vegyeszet | Process for producing pharmaceutical solution of new type polynuclear iron/iii/ mixed complex activity |
| CS245379B1 (cs) | 1983-12-12 | 1986-09-18 | Karel Capek | Způsob výroby komplexů sacharózy s biogenními prvky |
| US4788281A (en) * | 1984-01-04 | 1988-11-29 | Tosoni Anthony L | Dextran hexonic acid derivative, ferric hydroxide complex and method manufacture thereof |
| DE3443251C2 (de) * | 1984-11-23 | 1998-03-12 | Schering Ag | Eisenoxid-Komplexe für die NMR-Diagnostik, diese Verbindungen enthaltende diagnostische Mittel, ihre Verwendung und Verfahren zu deren Herstellung |
| US5746999A (en) * | 1984-11-23 | 1998-05-05 | Schering Aktiengesellschaft | Magnetic particles for diagnostic purposes |
| US4640837A (en) | 1985-10-15 | 1987-02-03 | General Foods Corporation | Coating composition for microwave cooking |
| US5160726A (en) * | 1990-02-15 | 1992-11-03 | Advanced Magnetics Inc. | Filter sterilization for production of colloidal, superparamagnetic MR contrast agents |
| US5102652A (en) | 1986-07-03 | 1992-04-07 | Advanced Magnetics Inc. | Low molecular weight carbohydrates as additives to stabilize metal oxide compositions |
| NO881507D0 (no) | 1987-04-10 | 1988-04-07 | Ortho Pharma Corp | Fremgangsmaate for forhoeyning av hematokritnivaaet til et normalt pattedyr. |
| CN1038753C (zh) * | 1988-10-14 | 1998-06-17 | 广西化工研究所 | 葡聚糖铁的制备方法 |
| GB8902894D0 (en) | 1989-02-09 | 1989-03-30 | Fisons Plc | Compositions |
| JP2726520B2 (ja) | 1989-10-20 | 1998-03-11 | 名糖産業株式会社 | 有機磁性複合体 |
| ES2074528T3 (es) | 1989-11-10 | 1995-09-16 | Tno | Metodo para la preparacion de polidicarboxisacaridos. |
| ES2110500T3 (es) | 1991-06-11 | 1998-02-16 | Meito Sangyo Kk | Material compuesto oxidado que comprende carboxipolisacarido soluble en agua y oxido de hierro magnetico. |
| TW293036B (ar) | 1992-11-27 | 1996-12-11 | Takeda Pharm Industry Co Ltd | |
| EP0634174A1 (en) | 1993-07-13 | 1995-01-18 | Takeda Chemical Industries, Ltd. | Antianemic composition for veterinary use |
| NL194919C (nl) | 1993-09-07 | 2003-07-04 | Tno | Werkwijze voor het oxideren van koolhydraten. |
| FR2720398B1 (fr) * | 1994-05-26 | 1996-07-05 | Commissariat Energie Atomique | Complexes de métaux trivalents avec un polyol tel que le cis-inositol, utilisables à des fins médicales et leur procédé de préparation. |
| GB9514090D0 (en) | 1995-07-11 | 1995-09-13 | Cerestar Holding Bv | Non-catalysed oxidation of maltodextrin with an oxygen containing oxidant |
| US5624668A (en) | 1995-09-29 | 1997-04-29 | Luitpold Pharmaceuticals, Inc. | Iron dextran formulations |
| JP2000500175A (ja) | 1995-11-09 | 2000-01-11 | アボツト・ラボラトリーズ | 結晶質鉄デキストランの製造方法 |
| FR2742755B1 (fr) * | 1995-12-21 | 1998-02-20 | Roquette Freres | Procede perfectionne d'oxydation des sucres |
| US5756715A (en) | 1996-11-08 | 1998-05-26 | Abbott Laboratories | Process for making crystalline iron dextran |
| CA2195283C (en) | 1997-01-16 | 2008-07-22 | Thomas C. Usher | Process for manufacturing iron dextran using ultrafiltration |
| IT1291289B1 (it) | 1997-04-30 | 1999-01-07 | Derivati Organici Lab | Complessi costituiti da fe(iii) un composto poliidrossilato e ovalbumina |
| DK172860B1 (da) | 1998-03-25 | 1999-08-16 | Pharmacosmos Holding As | Jerndextranforbindelse til anvendelse som komponent i et terapeutisk middel til forebyggelse af eller behandling af jernman |
| DE19833548A1 (de) | 1998-07-25 | 2000-02-03 | Messer Griesheim Gmbh | Überkritische Fluorierung |
| US6587550B2 (en) | 1998-09-02 | 2003-07-01 | Michael O. Council | Method and apparatus for enabling a fee to be charged to a party initiating an electronic mail communication when the party is not on an authorization list associated with the party to whom the communication is directed |
| DK173138B1 (da) | 1998-11-20 | 2000-02-07 | Pharmacosmos Holding As | Fremgangsmåde til fremstilling af en jerndextranforbindelse, jerndextranforbindelse fremstillet efter fremgangsmåden, farma |
| WO2000061191A2 (en) | 1999-04-09 | 2000-10-19 | Advanced Magnetics, Inc. | Heat stable coated colloidal iron oxides |
| US7871597B2 (en) | 1999-04-09 | 2011-01-18 | Amag Pharmaceuticals, Inc. | Polyol and polyether iron oxide complexes as pharmacological and/or MRI contrast agents |
| US6703499B1 (en) | 1999-04-29 | 2004-03-09 | Polydex Pharmaceuticals Ltd. | Process of making carboxylated dextran |
| US6495177B1 (en) | 1999-08-13 | 2002-12-17 | Warner Chilcott Laboratories Ireland Limited | Orally dissolvable nutritional supplement |
| US6521247B1 (en) | 1999-08-13 | 2003-02-18 | Warner Chilcott Laboratories Ireland Limited | Dual iron containing nutritional supplement |
| AT500063A1 (de) | 1999-11-23 | 2005-10-15 | Sandoz Ag | Beschichtete tablettenkerne |
| US20020119174A1 (en) | 2000-07-26 | 2002-08-29 | Gardlik John Michael | Compositions useful for regulating hair growth containing metal complexes of oxidized carbohydrates |
| US6929954B2 (en) * | 2000-11-02 | 2005-08-16 | Chromaceutical Advanced Technologies, Inc. | Method for producing purified hematinic iron-saccharidic complex and product produced |
| EP1719495A3 (en) | 2000-11-02 | 2007-05-02 | Chromaceutical Advanced Technologies, Inc. | Method for producing purified hematinic iron-saccharidic complex and product produced |
| CN1473265B (zh) * | 2000-11-02 | 2011-10-12 | 色品先进技术股份有限公司 | 生产纯化的补血铁-糖复合物的方法及产品的生产 |
| CN1353194A (zh) * | 2000-11-02 | 2002-06-12 | 杨敏 | 生产20%右旋糖酐铁的方法 |
| AU2002220280A1 (en) * | 2000-12-07 | 2002-06-18 | Ad "Zdravlje" Farmaceutsko - Hemijska Industrija, Centar Za Istrazivanje I Razvoj | Polynuclear complex fe(iii) with pullulan oligomers, process of its obtaining, and pharmaceutical preparations on the basis of the complex |
| JP2002260951A (ja) | 2000-12-28 | 2002-09-13 | Denso Corp | 積層型誘電素子及びその製造方法,並びに電極用ペースト材料 |
| AU2003226923B2 (en) | 2002-04-09 | 2006-08-17 | Pharmacosmos Holding A/S | iron dextrin compounds for the treatment of iron deficiency anaemia |
| CN1674942A (zh) | 2002-06-21 | 2005-09-28 | 联邦高等教育系统匹兹堡大学 | 氧化氮、血红素加氧酶-1和血红素降解产物的药学用途 |
| US7169359B2 (en) * | 2002-08-26 | 2007-01-30 | Luitpold Pharmaceuticals, Inc. | Bioequivalence test for iron-containing formulations |
| CA2494199C (en) | 2002-08-26 | 2007-02-06 | Luitpold Pharmaceuticals, Inc. | Bioequivalence test for iron-containing formulations |
| DE10249552A1 (de) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydrat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| US6960571B2 (en) * | 2003-03-14 | 2005-11-01 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron for the treatment of restless leg syndrome |
| US20060116349A1 (en) | 2003-03-14 | 2006-06-01 | Luitpold Pharmaceuticals, Inc. | Methods and compositions for administration of iron for the treatment of restless leg syndrome |
| US7964568B2 (en) * | 2003-05-30 | 2011-06-21 | Chromaceutical Advanced Technologies, Inc. | Synthesis of high molecular weight iron-saccharidic complexes |
| US8614204B2 (en) | 2003-06-06 | 2013-12-24 | Fibrogen, Inc. | Enhanced erythropoiesis and iron metabolism |
| KR20060108692A (ko) | 2003-10-31 | 2006-10-18 | 알자 코포레이션 | 메트포르민의 개선된 흡수를 위한 조성물 및 제형 |
| US20060134227A1 (en) | 2004-12-22 | 2006-06-22 | Bortz Jonathan D | Compositions including iron |
| MX2007009588A (es) | 2005-02-09 | 2007-09-12 | Vifor Int Ag | Uso de compuestos de complejo de hierro(iii). |
| US7815621B2 (en) * | 2005-07-07 | 2010-10-19 | Eisai R & D Management Co. Ltd. | Recovery system |
| EP1757299A1 (de) | 2005-08-25 | 2007-02-28 | Vifor (International) Ag | Eisen(III)-Komplexverbindungen zur Behandlung von Eisenmangel-Zuständen bei Patienten mit chronisch-entzündlicher Darmerkrankung |
| US7660481B2 (en) | 2005-11-17 | 2010-02-09 | Vital Images, Inc. | Image enhancement using anisotropic noise filtering |
| EP1790356A1 (de) * | 2005-11-24 | 2007-05-30 | Vifor (International) Ag | Präparat, umfassend Eisen(III)-Komplexverbindungen und redoxaktive Substanz(en) |
| PT1973549T (pt) | 2006-01-06 | 2016-10-25 | Luitpold Pharm Inc | Métodos e composições para administração de ferro |
| US8778878B2 (en) | 2007-01-29 | 2014-07-15 | Chyna, LLC | Use of ferritin to treat iron disorders |
| US8071542B2 (en) | 2007-01-29 | 2011-12-06 | Chyna, LLC | Use of ferritin to treat iron deficiency disorders |
| EP1997833A1 (de) * | 2007-05-29 | 2008-12-03 | Vifor (International) Ag | Wasserlösliche Eisen-Kohlenhydratderivat-Komplexe, deren Herstellung und diese enthaltende Arzneimittel |
| EP2496595A2 (en) | 2009-11-04 | 2012-09-12 | Symed Labs Limited | Process for the preparation of iron (iii) carboxymaltose complex |
| BRPI0904979A2 (pt) | 2009-12-04 | 2011-07-19 | Braskem S.A. | processo para produção de olefinas, olefina, poliolefina, e, uso da poliolefina |
| US9120838B2 (en) | 2011-04-18 | 2015-09-01 | Curators Of The University Of Missouri | Saccharide conjugates |
| US8772101B2 (en) | 2012-11-08 | 2014-07-08 | Globalfoundries Inc. | Methods of forming replacement gate structures on semiconductor devices and the resulting device |
| CN107438626A (zh) | 2015-03-23 | 2017-12-05 | 苏文生命科学有限公司 | 水溶性三价铁碳水化合物复合物的制备 |
| WO2016181195A1 (en) | 2015-05-08 | 2016-11-17 | Suven Life Sciences Limited | Improved process for water soluble iron carbohydrate complexes |
| EP3339329A1 (en) | 2016-12-22 | 2018-06-27 | LEK Pharmaceuticals d.d. | Selective oxidation of maltodextrin and its use in the preparation of water-soluble iron (iii) carboxymaltose complexes |
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