JO3446B1 - طريقة لمعالجة الأرق الأولي - Google Patents

طريقة لمعالجة الأرق الأولي

Info

Publication number
JO3446B1
JO3446B1 JOP/2002/0086A JOP20020086A JO3446B1 JO 3446 B1 JO3446 B1 JO 3446B1 JO P20020086 A JOP20020086 A JO P20020086A JO 3446 B1 JO3446 B1 JO 3446B1
Authority
JO
Jordan
Prior art keywords
melatonin
primary insomnia
treating primary
factors
insomnia
Prior art date
Application number
JOP/2002/0086A
Other languages
English (en)
Inventor
Nava Zisapel
Original Assignee
Neurim Pharmaceuticals S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11075696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3446(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurim Pharmaceuticals S A filed Critical Neurim Pharmaceuticals S A
Application granted granted Critical
Publication of JO3446B1 publication Critical patent/JO3446B1/ar

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

يتعلق هذا الاختراع بدواء لمعالجة وتحسين النوعية المعيدة للصحة للنوم في مريض يعاني من الأرق الأولي، يشتمل على مركب واحد على الأقل يختار من ميلاتونين، عوامل مولدة للميلاتونين، عوامل تألف الميلاتونين وعوامل ضادة للملايتونين بمقدار فعال ضمن المدى من 0.0025 الى 50مجج ويجوز أن يشتمل على عامل فعال علاجيا واحد أو كثر
JOP/2002/0086A 2001-08-14 2002-08-08 طريقة لمعالجة الأرق الأولي JO3446B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL144900A IL144900A (en) 2001-08-14 2001-08-14 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs

Publications (1)

Publication Number Publication Date
JO3446B1 true JO3446B1 (ar) 2020-07-05

Family

ID=11075696

Family Applications (1)

Application Number Title Priority Date Filing Date
JOP/2002/0086A JO3446B1 (ar) 2001-08-14 2002-08-08 طريقة لمعالجة الأرق الأولي

Country Status (35)

Country Link
US (1) US8962024B2 (ar)
EP (2) EP3103443B1 (ar)
JP (1) JP2005501095A (ar)
KR (1) KR20040032917A (ar)
CN (1) CN100453078C (ar)
AR (1) AR034975A1 (ar)
AU (1) AU2002326114C1 (ar)
BR (1) BR0211855A (ar)
CA (1) CA2454699C (ar)
CL (1) CL2002001701A1 (ar)
CR (1) CR7271A (ar)
CY (2) CY1118924T1 (ar)
DK (2) DK1441702T3 (ar)
EA (1) EA200400302A1 (ar)
ES (2) ES2882584T3 (ar)
GT (1) GT200200164A (ar)
HU (1) HU230786B1 (ar)
IL (1) IL144900A (ar)
IS (1) IS3004B (ar)
JO (1) JO3446B1 (ar)
LT (1) LT1441702T (ar)
MX (1) MXPA04001372A (ar)
NO (1) NO334788B1 (ar)
NZ (1) NZ531318A (ar)
PA (1) PA8552301A1 (ar)
PE (1) PE20030331A1 (ar)
PL (1) PL367872A1 (ar)
PT (2) PT3103443T (ar)
PY (1) PY0218122A (ar)
RU (1) RU2560840C2 (ar)
SI (1) SI1441702T1 (ar)
UA (1) UA87262C2 (ar)
UY (1) UY27401A1 (ar)
WO (1) WO2003015690A2 (ar)
ZA (1) ZA200402005B (ar)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
AR056076A1 (es) * 2005-09-20 2007-09-19 Takeda Pharmaceutical Agente profilactico o terapeutico para el desorden de sueno
US20070088079A1 (en) * 2005-09-20 2007-04-19 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for sleep disorder
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
US8940326B2 (en) 2007-03-19 2015-01-27 Vita Sciences Llc Transdermal patch and method for delivery of vitamin B12
WO2008122102A1 (en) * 2007-04-05 2008-10-16 Iomedix Development International Srl Melatonin-based composition for improved sleep
US20080248106A1 (en) 2007-04-05 2008-10-09 Marvin Heuer Melatonin-based composition for improved sleep
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
WO2012103411A2 (en) * 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same
SG11201903829PA (en) 2016-10-31 2019-05-30 Neurim Pharma 1991 Melatonin mini-tablets and method of manufacturing the same

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IT1251544B (it) 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico
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IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
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Also Published As

Publication number Publication date
BR0211855A (pt) 2004-09-21
EA200400302A1 (ru) 2004-10-28
IS7136A (is) 2004-01-30
CN100453078C (zh) 2009-01-21
PA8552301A1 (es) 2003-06-30
DK3103443T3 (da) 2021-08-30
NZ531318A (en) 2005-08-26
AU2002326114A1 (en) 2003-03-03
NO20040087L (no) 2004-02-19
NO334788B2 (no) 2014-05-26
PE20030331A1 (es) 2003-06-27
UA87262C2 (uk) 2009-07-10
EP1441702B1 (en) 2017-05-10
GT200200164A (es) 2003-09-26
EP3103443B1 (en) 2021-06-30
CA2454699A1 (en) 2003-02-27
EP1441702A4 (en) 2007-09-26
NO334788B1 (no) 2014-05-26
HU230786B1 (en) 2018-05-02
US20040248966A1 (en) 2004-12-09
UY27401A1 (es) 2003-02-28
CY1124763T1 (el) 2022-07-22
PL367872A1 (en) 2005-03-07
RU2560840C2 (ru) 2015-08-20
CN1541092A (zh) 2004-10-27
SI1441702T1 (sl) 2017-08-31
CL2002001701A1 (es) 2010-06-25
PT3103443T (pt) 2021-08-12
KR20040032917A (ko) 2004-04-17
WO2003015690A2 (en) 2003-02-27
HUP0401042A2 (hu) 2004-08-30
WO2003015690A3 (en) 2003-09-25
MXPA04001372A (es) 2005-06-06
CA2454699C (en) 2012-03-27
AU2002326114C1 (en) 2019-03-21
DK1441702T3 (en) 2017-06-06
HK1066161A1 (zh) 2005-03-18
IL144900A0 (en) 2002-06-30
IS3004B (is) 2018-09-15
CR7271A (es) 2004-05-17
PY0218122A (es) 2004-03-01
ES2626591T3 (es) 2017-07-25
IL144900A (en) 2013-12-31
CY1118924T1 (el) 2018-01-10
PT1441702T (pt) 2017-06-02
JP2005501095A (ja) 2005-01-13
WO2003015690B1 (en) 2004-03-11
HUP0401042A3 (en) 2009-07-28
US8962024B2 (en) 2015-02-24
LT1441702T (lt) 2017-06-12
ES2882584T3 (es) 2021-12-02
ZA200402005B (en) 2005-07-27
EP3103443A1 (en) 2016-12-14
AR034975A1 (es) 2004-03-24
RU2011131532A (ru) 2013-03-27
EP1441702A2 (en) 2004-08-04
AU2002326114B2 (en) 2007-03-08

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