JOP20170147B1 - تركيبة عينية تشتمل على زيت الخروع ودهون ثلاثية متوسطة السلسلة - Google Patents

تركيبة عينية تشتمل على زيت الخروع ودهون ثلاثية متوسطة السلسلة

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Publication number
JOP20170147B1
JOP20170147B1 JOP/2017/0147A JOP20170147A JOP20170147B1 JO P20170147 B1 JOP20170147 B1 JO P20170147B1 JO P20170147 A JOP20170147 A JO P20170147A JO P20170147 B1 JOP20170147 B1 JO P20170147B1
Authority
JO
Jordan
Prior art keywords
castor oil
medium chain
chain triglycerides
epithelial
includes castor
Prior art date
Application number
JOP/2017/0147A
Other languages
English (en)
Inventor
Izquierdo Torres Francisca
Marchan Sancho Sandra
DELGADO GANAN Isabel
Original Assignee
Salvat Lab Sa
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Publication date
Application filed by Salvat Lab Sa filed Critical Salvat Lab Sa
Publication of JOP20170147A1 publication Critical patent/JOP20170147A1/ar
Application granted granted Critical
Publication of JOP20170147B1 publication Critical patent/JOP20170147B1/ar

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Nanotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

يتعلق الاختراع الحالي بتركيبة خاصة بالعيون تشتمل على زيت خروع وثلاثي جليسريد ذو سلسلة متوسطة، وباستخدامها في الطب، تحديدا لعلاج و/أو الوقاية من مرض عيني منتقى من المجموعة التي تتكون من جفاف العين، التهاب الملتحمة، التهاب الأدمة، التهاب الجفن، الشتر الداخلي، متلازمة الجفن المترهل، اعتلال العين الدرقي المنشأ، الظفرة، التهاب الملتحمة اللارتخائي، التلف الظهاري المستحث بالمواد الحافظة، تلف الغرفة الظهاري أو السابق المستحث بجراحة العين، خلل الخلية الحوفي، تقرحات القرنية المستحثة بالعوامل الفيزيائية او الكيميائية، التهاب القرنية، التهاب ظاهر الصلبة والتهاب القزحية.
JOP/2017/0147A 2016-07-07 2016-07-07 تركيبة عينية تشتمل على زيت الخروع ودهون ثلاثية متوسطة السلسلة JOP20170147B1 (ar)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16382321.4A EP3266446B1 (en) 2016-07-07 2016-07-07 Ophthalmic composition comprising castor oil and medium chain triglyceride

Publications (2)

Publication Number Publication Date
JOP20170147A1 JOP20170147A1 (ar) 2019-01-30
JOP20170147B1 true JOP20170147B1 (ar) 2021-08-17

Family

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Family Applications (1)

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JOP/2017/0147A JOP20170147B1 (ar) 2016-07-07 2016-07-07 تركيبة عينية تشتمل على زيت الخروع ودهون ثلاثية متوسطة السلسلة

Country Status (14)

Country Link
US (1) US10660848B2 (ar)
EP (1) EP3266446B1 (ar)
JP (1) JP7224095B2 (ar)
CN (1) CN107582605B (ar)
DK (1) DK3266446T3 (ar)
ES (1) ES2706535T3 (ar)
HR (1) HRP20190036T1 (ar)
JO (1) JOP20170147B1 (ar)
LT (1) LT3266446T (ar)
PL (1) PL3266446T3 (ar)
PT (1) PT3266446T (ar)
RS (1) RS58292B1 (ar)
RU (1) RU2756758C2 (ar)
SI (1) SI3266446T1 (ar)

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Also Published As

Publication number Publication date
US20180008538A1 (en) 2018-01-11
SI3266446T1 (sl) 2019-02-28
RU2756758C2 (ru) 2021-10-05
DK3266446T3 (en) 2019-02-11
ES2706535T3 (es) 2019-03-29
LT3266446T (lt) 2019-01-25
CN107582605A (zh) 2018-01-16
JOP20170147A1 (ar) 2019-01-30
PT3266446T (pt) 2019-01-30
CN107582605B (zh) 2026-06-09
HRP20190036T1 (hr) 2019-02-22
RU2017123797A (ru) 2019-01-09
JP2018039781A (ja) 2018-03-15
RS58292B1 (sr) 2019-03-29
EP3266446A1 (en) 2018-01-10
PL3266446T3 (pl) 2019-05-31
JP7224095B2 (ja) 2023-02-17
US10660848B2 (en) 2020-05-26
RU2017123797A3 (ar) 2020-09-18
EP3266446B1 (en) 2018-11-21

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