JP2000509707A - 免疫原性複合体、その使用、製造法およびそれを含有するワクチン - Google Patents
免疫原性複合体、その使用、製造法およびそれを含有するワクチンInfo
- Publication number
- JP2000509707A JP2000509707A JP9539595A JP53959597A JP2000509707A JP 2000509707 A JP2000509707 A JP 2000509707A JP 9539595 A JP9539595 A JP 9539595A JP 53959597 A JP53959597 A JP 53959597A JP 2000509707 A JP2000509707 A JP 2000509707A
- Authority
- JP
- Japan
- Prior art keywords
- protein
- seq
- salmonella
- oligosaccharide
- immunogenic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 239000006166 lysate Substances 0.000 description 1
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- 230000003446 memory effect Effects 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
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- 239000002777 nucleoside Substances 0.000 description 1
- 125000003835 nucleoside group Chemical group 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
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- 230000007170 pathology Effects 0.000 description 1
- 108010091718 peptide L Proteins 0.000 description 1
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- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 description 1
- 150000008300 phosphoramidites Chemical class 0.000 description 1
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- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
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- HEBKCHPVOIAQTA-ZXFHETKHSA-N ribitol Chemical compound OC[C@H](O)[C@H](O)[C@H](O)CO HEBKCHPVOIAQTA-ZXFHETKHSA-N 0.000 description 1
- 238000013207 serial dilution Methods 0.000 description 1
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- 229910001961 silver nitrate Inorganic materials 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
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- 238000010186 staining Methods 0.000 description 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 1
- 229940031626 subunit vaccine Drugs 0.000 description 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009182 swimming Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
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- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 150000004044 tetrasaccharides Chemical class 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- ZWZVWGITAAIFPS-UHFFFAOYSA-N thiophosgene Chemical compound ClC(Cl)=S ZWZVWGITAAIFPS-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR96/05692 | 1996-05-07 | ||
| FR9605692A FR2748476B1 (fr) | 1996-05-07 | 1996-05-07 | Complexe immunogene, son utilisation, son procede de preparation et vaccin le contenant |
| PCT/FR1997/000800 WO1997041888A1 (fr) | 1996-05-07 | 1997-05-06 | Complexe immunogene, son utilisation, son procede de preparation et vaccin le contenant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2000509707A true JP2000509707A (ja) | 2000-08-02 |
Family
ID=9491907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9539595A Pending JP2000509707A (ja) | 1996-05-07 | 1997-05-06 | 免疫原性複合体、その使用、製造法およびそれを含有するワクチン |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0914152A1 (fr) |
| JP (1) | JP2000509707A (fr) |
| CN (1) | CN1221348A (fr) |
| AU (1) | AU733845B2 (fr) |
| BR (1) | BR9708979A (fr) |
| CA (1) | CA2254084A1 (fr) |
| FR (1) | FR2748476B1 (fr) |
| NZ (1) | NZ332809A (fr) |
| WO (1) | WO1997041888A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009523736A (ja) * | 2006-01-13 | 2009-06-25 | バクスター・インターナショナル・インコーポレイテッド | ポリサッカライドを精製する方法 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2776521B1 (fr) * | 1998-03-27 | 2000-12-15 | Pf Medicament | Utilisation de conjugues p40 actifs par voie nasale |
| FR2785542B1 (fr) * | 1998-11-06 | 2001-02-09 | Pf Medicament | UTILISATION D'UNE PROTEINE OmpA D'ENTEROBACTERIE, POUR LE CIBLAGE SPECIFIQUE D'UNE SUBSTANCE BIOLOGIQUEMENT ACTIVE QUI LUI EST ASSOCIEE VERS LES CELLULES PRESENTATRICES D'ANTIGENES TELLES QUE LES CELLULES DENDRITIQUES HUMAINES |
| US6146902A (en) * | 1998-12-29 | 2000-11-14 | Aventis Pasteur, Inc. | Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions |
| FR2789588B1 (fr) * | 1999-02-17 | 2001-05-04 | Pf Medicament | Utilisation d'une proteine ompa d'enterobacterie associee a un antigene dans une composition pharmaceutique destinee a generer ou accroitre une reponse cytotoxique antivirale, antiparasitaire ou antitumorale |
| FR2789902A1 (fr) * | 1999-02-24 | 2000-08-25 | Pf Medicament | PROTEINE OmpA DE KLEBSIELLA PNEUMONIAE ASSOCIEE A LA CHAINE BETA DE L'HORMONE hCG OU A UN COMPOSE IMPLIQUE DANS LA PROLIFERATION DE CELLULES TUMORALES OU DANS LA FERTILITE, UTILE DANS UNE COMPOSITION PHARMACEUTIQUE |
| FR2790959B1 (fr) * | 1999-03-15 | 2003-06-27 | Pf Medicament | Utilisation de fractions membranaires bacteriennes a effet adjuvant, leurs procedes de preparation et composition pharmaceutique les contenant |
| FR2828106A1 (fr) * | 2001-08-02 | 2003-02-07 | Pf Medicament | Utilisation d'une omp d'enterobacterie de faible masse moleculaire comme porteur et/ou adjuvant |
| CN107184972B (zh) * | 2017-06-20 | 2020-12-01 | 康希诺生物股份公司 | 一种结核杆菌OS-tb寡糖缀合物及其制备方法与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1331355C (fr) * | 1986-04-21 | 1994-08-09 | Bioenterprises Pty. Ltd | Immunopotentialisation |
| FR2682388B1 (fr) * | 1991-10-10 | 1995-06-09 | Pasteur Merieux Serums Vacc | Procede de preparation d'un oligoside par depolymerisation d'un polyoside issu d'un agent pathogene, oligoside ainsi obtenu et son utilisation notamment comme agent vaccinal. |
| US6153406A (en) * | 1993-07-23 | 2000-11-28 | North American Vaccine, Inc. | Method for the high level expression, purification and refolding of the outer membrane protein P2 from Haemophilus influenzae type B |
| FR2718452B1 (fr) * | 1994-04-06 | 1996-06-28 | Pf Medicament | Elément d'immunogène, agent immunogène, composition pharmaceutique et procédé de préparation. |
| FR2726472B1 (fr) * | 1994-11-07 | 1997-01-31 | Pf Medicament | Proteine porteuse a effet adjuvant, complexe immunogene la contenant, leur procede de preparation, sequence nucleotidique et vaccin |
| FR2726471B1 (fr) * | 1994-11-07 | 1997-01-31 | Pf Medicament | Procede pour ameliorer l'immunogenicite d'un compose immunogene ou d'un haptene et application a la preparation de vaccins |
-
1996
- 1996-05-07 FR FR9605692A patent/FR2748476B1/fr not_active Expired - Fee Related
-
1997
- 1997-05-06 CA CA002254084A patent/CA2254084A1/fr not_active Abandoned
- 1997-05-06 JP JP9539595A patent/JP2000509707A/ja active Pending
- 1997-05-06 AU AU29019/97A patent/AU733845B2/en not_active Ceased
- 1997-05-06 EP EP97923139A patent/EP0914152A1/fr not_active Withdrawn
- 1997-05-06 BR BR9708979A patent/BR9708979A/pt not_active Application Discontinuation
- 1997-05-06 CN CN97195397A patent/CN1221348A/zh active Pending
- 1997-05-06 NZ NZ332809A patent/NZ332809A/xx unknown
- 1997-05-06 WO PCT/FR1997/000800 patent/WO1997041888A1/fr not_active Ceased
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009523736A (ja) * | 2006-01-13 | 2009-06-25 | バクスター・インターナショナル・インコーポレイテッド | ポリサッカライドを精製する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0914152A1 (fr) | 1999-05-12 |
| NZ332809A (en) | 2000-05-26 |
| FR2748476A1 (fr) | 1997-11-14 |
| WO1997041888A1 (fr) | 1997-11-13 |
| CN1221348A (zh) | 1999-06-30 |
| AU733845B2 (en) | 2001-05-31 |
| FR2748476B1 (fr) | 1998-08-14 |
| CA2254084A1 (fr) | 1997-11-13 |
| BR9708979A (pt) | 1999-08-03 |
| AU2901997A (en) | 1997-11-26 |
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