JP2004534075A - Ｔｆｆダイマーペプチドによる粘膜修復 - Google Patents

Ｔｆｆダイマーペプチドによる粘膜修復 Download PDF

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Publication number
JP2004534075A
JP2004534075A JP2003504989A JP2003504989A JP2004534075A JP 2004534075 A JP2004534075 A JP 2004534075A JP 2003504989 A JP2003504989 A JP 2003504989A JP 2003504989 A JP2003504989 A JP 2003504989A JP 2004534075 A JP2004534075 A JP 2004534075A
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JP
Japan
Prior art keywords
pharmaceutical composition
composition according
viscosity
disease state
mucin
Prior art date
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Pending
Application number
JP2003504989A
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English (en)
Japanese (ja)
Inventor
ティム，ラルス
セイエル ポウルセン，ステーン
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Novo Nordisk AS
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Novo Nordisk AS
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Publication of JP2004534075A publication Critical patent/JP2004534075A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003504989A 2001-06-14 2002-06-13 Ｔｆｆダイマーペプチドによる粘膜修復 Pending JP2004534075A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200100926 2001-06-14
PCT/DK2002/000396 WO2002102403A1 (fr) 2001-06-14 2002-06-13 Reparation des muqueuses par des peptides dimeres tff

Publications (1)

Publication Number Publication Date
JP2004534075A true JP2004534075A (ja) 2004-11-11

Family

ID=8160561

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003504989A Pending JP2004534075A (ja) 2001-06-14 2002-06-13 Ｔｆｆダイマーペプチドによる粘膜修復

Country Status (3)

Country Link
EP (1) EP1401481A1 (fr)
JP (1) JP2004534075A (fr)
WO (1) WO2002102403A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008525479A (ja) * 2004-12-22 2008-07-17 オークランド ユニサービシス リミテッド トレフォイル因子およびそれを用いた増殖性疾患の処置方法
JP2019530446A (ja) * 2016-09-13 2019-10-24 イントレクソン・アクトバイオテイクス・エヌブイＩｎｔｒｅｘｏｎ Ａｃｔｏｂｉｏｔｉｃｓ ＮＶ 粘膜付着性微生物

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6525018B1 (en) 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
WO2003068817A1 (fr) * 2002-02-11 2003-08-21 Novo Nordisk A/S Regulation de la viscosite des muqueuses par les peptides monomeres tff
US6984628B2 (en) 2003-07-15 2006-01-10 Allergan, Inc. Ophthalmic compositions comprising trefoil factor family peptides
EP1667705A1 (fr) 2003-10-03 2006-06-14 Allergan, Inc. Compositions et methodes comprenant des composes du type prostaglandine et peptides de la famille du facteur en feuille de trefle utiles pour le traitement du glaucome avec hyperemie reduite
US20070042951A1 (en) * 2003-10-08 2007-02-22 Allergan, Inc. Pharmaceutical compositions comprising alpha-2-adrenergics and trefoil factor family peptides
WO2005042010A1 (fr) * 2003-10-30 2005-05-12 Novo Nordisk A/S Utilisation de polypeptides en feuille de trefle dans le traitement du diabete
AU2005288080B2 (en) 2004-09-28 2011-10-13 Otsuka Pharmaceutical Co., Ltd. Carbostyril compound

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0278604A (ja) * 1988-09-13 1990-03-19 Ichimaru Pharcos Co Ltd 化粧料配合用水溶性ムチン又はそれを含有する化粧料配合用水溶液
JPH10504720A (ja) * 1994-08-26 1998-05-12 ノボ ノルディスク アクティーゼルスカブ 三つ葉状のペプチド２量体
WO1999051262A2 (fr) * 1998-04-03 1999-10-14 Chiron Corporation Utilisation d'igf1 pour traiter des maladies du cartilage articulaire
JP2000508618A (ja) * 1995-11-29 2000-07-11 アストラ・アクチエボラーグ 口腔乾燥症の処置におけるコリンエステラーゼ阻害剤の使用
JP2000508900A (ja) * 1996-04-12 2000-07-18 ザ ジェネラル ホスピタル コーポレーション 腸三葉型蛋白質
WO2000064930A2 (fr) * 1999-04-23 2000-11-02 Rhode Island Hospital, A Lifespan Partner Tribonectines
WO2001019422A1 (fr) * 1999-09-14 2001-03-22 Tepha, Inc. Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001015672A2 (fr) * 1999-08-26 2001-03-08 Governors Of The University Of Alberta Utilisation de dextrane comme agent mucoactif, methodes et compositions pharmaceutiques connexes
EP1341817A2 (fr) * 2000-12-08 2003-09-10 Novo Nordisk A/S Peptides tff

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0278604A (ja) * 1988-09-13 1990-03-19 Ichimaru Pharcos Co Ltd 化粧料配合用水溶性ムチン又はそれを含有する化粧料配合用水溶液
JPH10504720A (ja) * 1994-08-26 1998-05-12 ノボ ノルディスク アクティーゼルスカブ 三つ葉状のペプチド２量体
JP2000508618A (ja) * 1995-11-29 2000-07-11 アストラ・アクチエボラーグ 口腔乾燥症の処置におけるコリンエステラーゼ阻害剤の使用
JP2000508900A (ja) * 1996-04-12 2000-07-18 ザ ジェネラル ホスピタル コーポレーション 腸三葉型蛋白質
WO1999051262A2 (fr) * 1998-04-03 1999-10-14 Chiron Corporation Utilisation d'igf1 pour traiter des maladies du cartilage articulaire
WO2000064930A2 (fr) * 1999-04-23 2000-11-02 Rhode Island Hospital, A Lifespan Partner Tribonectines
WO2001019422A1 (fr) * 1999-09-14 2001-03-22 Tepha, Inc. Polyhydroxyalkanoate compositions for soft tissue repair, augmentation, and viscosupplementation

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
JPN5003019760, ＦＥＢＳ ＬＥＴＴＥＲＳ, 1998, Ｖｏｌ．４３９, Ｐ．１８０−１８４ *
JPN5003019761, ＩＮＶＥＳＴＩＧＡＴＩＶＥ ＯＰＨＴＨＡＬＭＯＬＯＧＹ ＆ ＶＩＳＵＡＬ ＳＣＩＥＮＣＥ, 1999, Ｖｏｌ．４０， Ｎｏ．１０, Ｐ．２２２０−２２２４ *
JPN5003019762, ＧＡＳＴＲＯＥＮＴＥＲＯＬＯＧＹ, 1996, Ｖｏｌ．１１０, Ｐ．４８９−４９７ *
JPN5003019763, ＧＵＴ, 1999, Ｖｏｌ．４５, Ｐ．５１６−５２２ *
JPN5003019764, ＣＥＬＬ ＴＩＳＳＵＥ ＲＥＳ, 2001, Ｖｏｌ．３０３, Ｐ．１０９−１１５ *
JPN6010002001, Ｊｏｕｒｎａｌ ｏｆ Ｐａｔｈｏｌｏｇｙ, 1998, ｖｏｌ．１８５, ｐ．１５３−１５８ *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008525479A (ja) * 2004-12-22 2008-07-17 オークランド ユニサービシス リミテッド トレフォイル因子およびそれを用いた増殖性疾患の処置方法
JP2019530446A (ja) * 2016-09-13 2019-10-24 イントレクソン・アクトバイオテイクス・エヌブイＩｎｔｒｅｘｏｎ Ａｃｔｏｂｉｏｔｉｃｓ ＮＶ 粘膜付着性微生物
JP7022743B2 (ja) 2016-09-13 2022-02-18 イントレクソン・アクトバイオテイクス・エヌブイ 粘膜付着性微生物
JP2022084579A (ja) * 2016-09-13 2022-06-07 イントレクソン・アクトバイオテイクス・エヌブイ 粘膜付着性微生物
JP7439148B2 (ja) 2016-09-13 2024-02-27 イントレクソン・アクトバイオテイクス・エヌブイ 粘膜付着性微生物

Also Published As

Publication number Publication date
WO2002102403A1 (fr) 2002-12-27
EP1401481A1 (fr) 2004-03-31

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