JP2006501202A5 - - Google Patents
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- Publication number
- JP2006501202A5 JP2006501202A5 JP2004523753A JP2004523753A JP2006501202A5 JP 2006501202 A5 JP2006501202 A5 JP 2006501202A5 JP 2004523753 A JP2004523753 A JP 2004523753A JP 2004523753 A JP2004523753 A JP 2004523753A JP 2006501202 A5 JP2006501202 A5 JP 2006501202A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- aryl
- independently
- group
- alkylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10233817A DE10233817A1 (de) | 2002-07-25 | 2002-07-25 | Substituierte Diarylheterocyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| PCT/EP2003/007891 WO2004011438A1 (de) | 2002-07-25 | 2003-07-18 | Diarylsubstituierte cyclische harnstoffderivate mit mch-modulatorischer wirkung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006501202A JP2006501202A (ja) | 2006-01-12 |
| JP2006501202A5 true JP2006501202A5 (2) | 2006-08-31 |
| JP4568113B2 JP4568113B2 (ja) | 2010-10-27 |
Family
ID=30128364
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004523753A Expired - Fee Related JP4568113B2 (ja) | 2002-07-25 | 2003-07-18 | Ｍｃｈ調節作用を有するジアリール置換環状尿素誘導体 |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1551810B1 (2) |
| JP (1) | JP4568113B2 (2) |
| AR (1) | AR040514A1 (2) |
| AT (1) | ATE535513T1 (2) |
| AU (2) | AU2003257465A1 (2) |
| BR (1) | BR0312916A (2) |
| CA (1) | CA2493924A1 (2) |
| DE (1) | DE10233817A1 (2) |
| IL (1) | IL166471A (2) |
| MX (1) | MXPA05001048A (2) |
| MY (1) | MY142551A (2) |
| PE (1) | PE20040702A1 (2) |
| TW (1) | TW200408627A (2) |
| WO (2) | WO2004012648A2 (2) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7241787B2 (en) | 2004-01-25 | 2007-07-10 | Sanofi-Aventis Deutschland Gmbh | Substituted N-cycloexylimidazolinones, process for their preparation and their use as medicaments |
| DE102004003811A1 (de) * | 2004-01-25 | 2005-08-11 | Aventis Pharma Deutschland Gmbh | Substituierte N-Cyclohexylimidazolinone, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel |
| WO2005094817A1 (en) * | 2004-03-23 | 2005-10-13 | The Regents Of The University Of California | Melanin-concentrating hormone receptor antagonists and methods of use |
| WO2006015279A1 (en) * | 2004-07-28 | 2006-02-09 | Neurogen Corporation | Heterocyclic diamine compounds as ligands of the melanin concentrating hormone receptor useful for the treatment of obesity, diabetes, eating and sexual disorders |
| EP1634598A1 (en) * | 2004-09-07 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion |
| JP5250967B2 (ja) * | 2005-11-30 | 2013-07-31 | 三菱化学株式会社 | 有機化合物、電荷輸送材料、電荷輸送材料用組成物および有機電界発光素子 |
| CN101287713A (zh) | 2005-11-30 | 2008-10-15 | 三菱化学株式会社 | 有机化合物、电荷传输材料、电荷传输材料用组合物和有机电致发光元件 |
| CA2626220A1 (en) | 2005-12-21 | 2007-06-28 | Janssen Pharmaceutica N.V. | Novel substituted pyrazinone derivatives for use in mch-1 mediated diseases |
| WO2007093365A2 (en) * | 2006-02-15 | 2007-08-23 | Sanofi-Aventis | Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments |
| EP2061767B1 (de) | 2006-08-08 | 2014-12-17 | Sanofi | Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung |
| EP2102208B1 (en) | 2006-12-05 | 2014-04-23 | Janssen Pharmaceutica NV | Novel substituted diaza spiro pyridinone derivatives for use in mch-1 mediated diseases |
| UY31968A (es) | 2008-07-09 | 2010-01-29 | Sanofi Aventis | Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos |
| DE102008049675A1 (de) | 2008-09-30 | 2010-04-01 | Markus Dr. Heinrich | Verfahren zur Herstellung von 3-Aminobiphenylen |
| EP2348857B1 (en) | 2008-10-22 | 2016-02-24 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| US8329914B2 (en) | 2008-10-31 | 2012-12-11 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| WO2010068601A1 (en) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof |
| KR20120060207A (ko) | 2009-08-26 | 2012-06-11 | 사노피 | 신규한 결정성 헤테로방향족 플루오로글리코시드 수화물, 이들 화합물을 포함하는 약제 및 이들의 용도 |
| JP2013520502A (ja) | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| SG192941A1 (en) | 2011-02-25 | 2013-09-30 | Merck Sharp & Dohme | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120058A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit benzyl- oder heteromethylengruppen substituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683699B1 (de) | 2011-03-08 | 2015-06-24 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| US8895547B2 (en) | 2011-03-08 | 2014-11-25 | Sanofi | Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof |
| EP2683704B1 (de) | 2011-03-08 | 2014-12-17 | Sanofi | Verzweigte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| WO2012120056A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
| EP2683702B1 (de) | 2011-03-08 | 2014-12-24 | Sanofi | Neue substituierte phenyl-oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
| WO2012120051A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit adamantan- oder noradamantan substituierte benzyl-oxathiazinderivate, diese verbindungen enthaltende arzneimittel und deren verwendung |
| RU2465895C1 (ru) * | 2011-09-08 | 2012-11-10 | Государственное образовательное учреждение высшего профессионального образования "Мордовский государственный университет им. Н.П. Огарева" | Способ лечения депрессивного невроза |
| RU2015106909A (ru) | 2012-08-02 | 2016-09-27 | Мерк Шарп И Доум Корп. | Антидиабетические трициклические соединения |
| KR20150118158A (ko) | 2013-02-22 | 2015-10-21 | 머크 샤프 앤드 돔 코포레이션 | 항당뇨병 비시클릭 화합물 |
| WO2014139388A1 (en) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
| CN105473558B (zh) | 2013-06-20 | 2019-04-19 | 拜耳作物科学股份公司 | 作为杀螨剂和杀昆虫剂的芳基硫化物衍生物和芳基硫氧化物衍生物 |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| WO2016100940A1 (en) | 2014-12-19 | 2016-06-23 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
| US10752588B2 (en) | 2014-12-19 | 2020-08-25 | The Broad Institute, Inc. | Dopamine D2 receptor ligands |
| US11072602B2 (en) | 2016-12-06 | 2021-07-27 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| EP3558298B1 (en) | 2016-12-20 | 2026-03-11 | Merck Sharp & Dohme LLC | Antidiabetic spirochroman compounds |
| WO2020140054A1 (en) | 2018-12-28 | 2020-07-02 | Spv Therapeutics Inc. | Cyclin-dependent kinase inhibitors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002649A3 (en) * | 1977-12-19 | 1979-07-11 | Sandoz Ag | 1-dimethyl-substituted alkyl-2- or 4-substituted phenylimidazoles, their production and their use as anti-obesity agents |
| DE4107857A1 (de) * | 1991-03-12 | 1992-09-17 | Thomae Gmbh Dr K | Cyclische harnstoffderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| WO1996025410A1 (en) * | 1995-02-17 | 1996-08-22 | Takeda Chemical Industries, Ltd. | Azole compounds, their production and use |
| FR2764889B1 (fr) * | 1997-06-20 | 2000-09-01 | Sod Conseils Rech Applic | Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
| US6096745A (en) * | 1998-03-25 | 2000-08-01 | Bristol-Myers Squibb Co. | Imidazolone anorectic agents: III. heteroaryl derivatives |
| JP2002003370A (ja) * | 1999-09-20 | 2002-01-09 | Takeda Chem Ind Ltd | メラニン凝集ホルモン拮抗剤 |
| JP2004516239A (ja) * | 2000-07-06 | 2004-06-03 | ニューロジェン コーポレイション | メラニン凝集ホルモン受容体リガンド |
| BR0112856A (pt) * | 2000-07-31 | 2003-07-01 | Smithkline Beecham Plc | Método para o tratamento dos distúrbios, composto ou um sal ou solvato deste, processo para a preparação dos mesmos, composição farmacêutico, método de tratamento e/ou profilaxia de um ou mais dos distúrbios, uso de um composto, e, método para o tratamento de diabetes, grande depressão, depressão manìaca, ansiedade, esquizofrenia e distúrbios do sono, em mamìferos humanos e não humanos |
| GT200100147A (es) * | 2000-07-31 | 2002-06-25 | Derivados de imidazol | |
| YU52403A (sh) * | 2000-12-26 | 2006-03-03 | Dr.Reddy's Research Foundation | Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže |
| GB0200283D0 (en) * | 2002-01-08 | 2002-02-20 | Smithkline Beecham Plc | Compounds |
-
2002
- 2002-07-25 DE DE10233817A patent/DE10233817A1/de not_active Withdrawn
-
2003
- 2003-07-15 AU AU2003257465A patent/AU2003257465A1/en not_active Abandoned
- 2003-07-15 WO PCT/EP2003/007639 patent/WO2004012648A2/de not_active Ceased
- 2003-07-18 AT AT03771060T patent/ATE535513T1/de active
- 2003-07-18 BR BR0312916-0A patent/BR0312916A/pt not_active IP Right Cessation
- 2003-07-18 MX MXPA05001048A patent/MXPA05001048A/es active IP Right Grant
- 2003-07-18 WO PCT/EP2003/007891 patent/WO2004011438A1/de not_active Ceased
- 2003-07-18 AU AU2003251001A patent/AU2003251001B9/en not_active Ceased
- 2003-07-18 JP JP2004523753A patent/JP4568113B2/ja not_active Expired - Fee Related
- 2003-07-18 EP EP03771060A patent/EP1551810B1/de not_active Expired - Lifetime
- 2003-07-18 CA CA002493924A patent/CA2493924A1/en not_active Abandoned
- 2003-07-21 PE PE2003000725A patent/PE20040702A1/es not_active Application Discontinuation
- 2003-07-23 MY MYPI20032759A patent/MY142551A/en unknown
- 2003-07-23 TW TW092120029A patent/TW200408627A/zh unknown
- 2003-07-23 AR AR20030102644A patent/AR040514A1/es unknown
-
2005
- 2005-01-17 IL IL166471A patent/IL166471A/en not_active IP Right Cessation
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