JP2008529536A - 加齢性黄斑変性を処置および診断するための方法および試薬 - Google Patents

加齢性黄斑変性を処置および診断するための方法および試薬 Download PDF

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JP2008529536A
JP2008529536A JP2007555366A JP2007555366A JP2008529536A JP 2008529536 A JP2008529536 A JP 2008529536A JP 2007555366 A JP2007555366 A JP 2007555366A JP 2007555366 A JP2007555366 A JP 2007555366A JP 2008529536 A JP2008529536 A JP 2008529536A
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JP2008529536A5 (2
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グレゴリー エス． ヘイグマン，
リチャード ジェイ． スミス，
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ユニバーシティー オブ アイオワ リサーチ ファウンデーション
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JP2007555366A 2005-02-14 2006-02-14 加齢性黄斑変性を処置および診断するための方法および試薬 Withdrawn JP2008529536A (ja)

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US65307805P 2005-02-14 2005-02-14
US71550305P 2005-09-09 2005-09-09
US71786105P 2005-09-16 2005-09-16
US73569705P 2005-11-09 2005-11-09
PCT/US2006/005313 WO2006088950A2 (en) 2005-02-14 2006-02-14 Methods and reagents for treatment and diagnosis of age-related macular degeneration

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JP2007555366A Withdrawn JP2008529536A (ja) 2005-02-14 2006-02-14 加齢性黄斑変性を処置および診断するための方法および試薬
JP2012049810A Expired - Fee Related JP5100901B2 (ja) 2005-02-14 2012-03-06 加齢性黄斑変性を処置および診断するための方法および試薬
JP2012180904A Withdrawn JP2012254089A (ja) 2005-02-14 2012-08-17 加齢性黄斑変性を処置および診断するための方法および試薬
JP2014123102A Pending JP2014204729A (ja) 2005-02-14 2014-06-16 加齢性黄斑変性を処置および診断するための方法および試薬

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JP2012049810A Expired - Fee Related JP5100901B2 (ja) 2005-02-14 2012-03-06 加齢性黄斑変性を処置および診断するための方法および試薬
JP2012180904A Withdrawn JP2012254089A (ja) 2005-02-14 2012-08-17 加齢性黄斑変性を処置および診断するための方法および試薬
JP2014123102A Pending JP2014204729A (ja) 2005-02-14 2014-06-16 加齢性黄斑変性を処置および診断するための方法および試薬

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US (8) US7745389B2 (2)
EP (5) EP2377951A1 (2)
JP (4) JP2008529536A (2)
KR (2) KR20070112801A (2)
CN (1) CN103920142A (2)
AT (1) ATE526421T1 (2)
AU (1) AU2006214320C1 (2)
CA (1) CA2597411C (2)
IL (2) IL185219A (2)
MX (1) MX2007009565A (2)
NZ (2) NZ595305A (2)
WO (1) WO2006088950A2 (2)

Cited By (5)

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JP2014513958A (ja) * 2011-04-29 2014-06-19 ユニヴァーシティー オブ ユタ リサーチ ファウンデーション 補体媒介性疾患の発症を予測する方法
JP2016519067A (ja) * 2013-03-14 2016-06-30 バックスアルタ インコーポレイテッド 関節リウマチの治療のためのｈ因子
JP2018537122A (ja) * 2015-10-28 2018-12-20 シンコナ インヴェストメント マネージメント リミティッド 遺伝子治療
JP2021523369A (ja) * 2018-05-10 2021-09-02 ザ・ユニバーシティ・オブ・マンチェスターＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｍａｎｃｈｅｓｔｅｒ 黄斑変性症を評価するための方法
JP2022500047A (ja) * 2018-09-13 2022-01-04 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. Ｃ３糸球体症のモデルとしての補体因子ｈ遺伝子ノックアウトラット

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US7745389B2 (en) * 2005-02-14 2010-06-29 University Of Iowa Research Foundation Methods for treatment of age-related macular degeneration
US8088587B2 (en) 2005-03-04 2012-01-03 Vanderbilt University Genetic variants increase the risk of age-related macular degeneration
US20070037183A1 (en) * 2005-03-07 2007-02-15 Trustees Of Boston University Diagnostic and therapeutic target for macular degeneration
WO2006128006A1 (en) * 2005-05-26 2006-11-30 The Regents Of The University Of Colorado Inhibition of the alternative complement pathway for treatment of traumatic brain injury, spinal cord injury and related conditions
EP1937706A4 (en) * 2005-09-09 2008-10-22 Univ Iowa Res Found ORGANIC MARKERS RELATED TO AGE DEPENDENT MAKULAR GENERATION
US8168584B2 (en) * 2005-10-08 2012-05-01 Potentia Pharmaceuticals, Inc. Methods of treating age-related macular degeneration by compstatin and analogs thereof
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KR20080087814A (ko) * 2005-12-22 2008-10-01 알콘 리서치, 리미티드 보체 인자 ｈ의 위험 변이체가 있는 환자에서 연령 관련황반변성의 예방 및 치료를 위한 ｃ3-전환효소 저해제
US20080146501A1 (en) * 2006-02-13 2008-06-19 University Of Iowa Research Foundation Protective complement proteins and age-related macular degeneration
WO2007120975A2 (en) 2006-02-13 2007-10-25 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Variants in complement regulatory genes predict age-related macular degeneration
US8012683B2 (en) 2006-02-13 2011-09-06 University Of Iowa Research Foundation Variants in complement regulatory genes predict age-related macular degeneration
GB0611606D0 (en) * 2006-06-13 2006-07-19 Univ Belfast Protection against and treatment of age related macular degeneration
US7759304B2 (en) * 2006-06-21 2010-07-20 Regents Of The University Of Colorado Targeting complement factor H for treatment of diseases
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ES2391788T3 (es) * 2006-07-26 2012-11-29 Yale University, Inc. Diagnóstico y tratamiento de degeneración macular relacionada con la edad
EP2054728A2 (en) * 2006-08-23 2009-05-06 University of Iowa Research Foundation Biomarkers associated with age-related macular degeneration
TW201716437A (zh) 2006-11-02 2017-05-16 建南德克公司 人類化之抗-因子ｄ抗體及其用途
GB0701213D0 (en) * 2007-01-23 2007-02-28 Univ Cardiff Factor H polymorphisms in the diagnosis and therapy of inflammatory diseases such as age-related macular degeneration
WO2008103299A2 (en) 2007-02-16 2008-08-28 Massachusetts Eye & Ear Infirmary Methods and compositions for prognosing, detecting, and treating age-related macular degeneration
CN101668773B (zh) 2007-03-14 2016-08-31 亚力史制药公司 人工程化抗b因子抗体
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CA2680833A1 (en) * 2007-04-30 2008-11-13 Alcon Research, Ltd. Treatment of age-related macular degeneration using inhibitors of complement factor d
EP2158330A2 (en) * 2007-05-11 2010-03-03 Tufts Medical Center Polynucleotides associated with age-related macular degeneration and methods for evaluating patient risk
WO2009029587A2 (en) * 2007-08-24 2009-03-05 The Regents Of The University Of Michigan Compositions and methods for diagnosing and treating macular degeneration
WO2009059321A2 (en) 2007-11-01 2009-05-07 University Of Iowa Research Foundation Rca locus analysis to assess susceptibility to amd and mpgnii
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US20110294682A1 (en) * 2008-04-28 2011-12-01 The General Hospital Corporation Polynucleotides Associated With Age-Related Macular Degeneration and Methods for Evaluating Patient Risks
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
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