JP2014503595A5 - - Google Patents

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Publication number: JP2014503595A5
Authority: JP; Japan
Prior art keywords: alkyl; group; substituted; coor; cycloalkyl
Prior art date: 2012-01-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP2013551362A

Other languages

English (en)

Japanese (ja)

Other versions

JP2014503595A (ja

JP6001560B2 (ja

Filing date

2012-01-27

Publication date

2015-02-26

2012-01-27 Application filed filed Critical

2012-01-27 Priority claimed from PCT/US2012/022852 external-priority patent/WO2012106190A1/en

2014-02-13 Publication of JP2014503595A publication Critical patent/JP2014503595A/ja

2015-02-26 Publication of JP2014503595A5 publication Critical patent/JP2014503595A5/ja

2016-10-05 Application granted granted Critical

2016-10-05 Publication of JP6001560B2 publication Critical patent/JP6001560B2/ja

Status Active legal-status Critical Current

2032-01-27 Anticipated expiration legal-status Critical

Links

125000000217 alkyl group Chemical group 0.000 claims 28
150000001875 compounds Chemical class 0.000 claims 21
125000001072 heteroaryl group Chemical group 0.000 claims 14
125000000547 substituted alkyl group Chemical group 0.000 claims 11
125000003118 aryl group Chemical group 0.000 claims 6
125000000753 cycloalkyl group Chemical group 0.000 claims 3
239000008194 pharmaceutical composition Substances 0.000 claims 3
150000003839 salts Chemical class 0.000 claims 3
-1 -C 3-6 cycloalkyl Chemical group 0.000 claims 2
208000030507 AIDS Diseases 0.000 claims 2
230000000840 anti-viral effect Effects 0.000 claims 2
229910052736 halogen Inorganic materials 0.000 claims 2
150000002367 halogens Chemical class 0.000 claims 2
125000000555 isopropenyl group Chemical group [H]\C([H])=C(\*)C([H])([H])[H] 0.000 claims 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 2
125000003107 substituted aryl group Chemical group 0.000 claims 2
229940126154 HIV entry inhibitor Drugs 0.000 claims 1
239000004480 active ingredient Substances 0.000 claims 1
125000003545 alkoxy group Chemical group 0.000 claims 1
229960005475 antiinfective agent Drugs 0.000 claims 1
239000004599 antimicrobial Substances 0.000 claims 1
239000003443 antiviral agent Substances 0.000 claims 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
239000003795 chemical substances by application Substances 0.000 claims 1
239000003085 diluting agent Substances 0.000 claims 1
239000003814 drug Substances 0.000 claims 1
239000003937 drug carrier Substances 0.000 claims 1
125000001475 halogen functional group Chemical group 0.000 claims 1
239000002835 hiv fusion inhibitor Substances 0.000 claims 1
230000002519 immonomodulatory effect Effects 0.000 claims 1
208000015181 infectious disease Diseases 0.000 claims 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
239000000546 pharmaceutical excipient Substances 0.000 claims 1
LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 1
229940124597 therapeutic agent Drugs 0.000 claims 1
0 CC(C)(C1CC2)C(**)=CC[C@]1(C)C(CC1)[C@]2(C)[C@@]2(C)[C@]1C(CCC1)[C@@]1(*)CC2 Chemical compound CC(C)(C1CC2)C(**)=CC[C@]1(C)C(CC1)[C@]2(C)[C@@]2(C)[C@]1C(CCC1)[C@@]1(*)CC2 0.000 description 2

JP2013551362A 2011-01-31 2012-01-27 Ｈｉｖ成熟阻害活性を有するｃ−１７およびｃ−３修飾トリテルペノイド Active JP6001560B2 (ja)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201161437893P	2011-01-31	2011-01-31
US61/437,893		2011-01-31
PCT/US2012/022852 WO2012106190A1 (en)	2011-01-31	2012-01-27	C-17 and c-3 modified triterpenoids with hiv maturation inhibitory activity

Publications (3)

Publication Number	Publication Date
JP2014503595A JP2014503595A (ja)	2014-02-13
JP2014503595A5 true JP2014503595A5 (2)	2015-02-26
JP6001560B2 JP6001560B2 (ja)	2016-10-05

Family

ID=45567147

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP2013551362A Active JP6001560B2 (ja)	2011-01-31	2012-01-27	Ｈｉｖ成熟阻害活性を有するｃ−１７およびｃ−３修飾トリテルペノイド

Country Status (25)

Country	Link
US (3)	US8846647B2 (2)
EP (1)	EP2670765B1 (2)
JP (1)	JP6001560B2 (2)
KR (1)	KR101886467B1 (2)
CN (1)	CN103429607B (2)
AR (1)	AR085053A1 (2)
AU (1)	AU2012212509B2 (2)
BR (1)	BR112013019419A2 (2)
CA (1)	CA2826113C (2)
CL (1)	CL2013002185A1 (2)
CO (1)	CO6751275A2 (2)
EA (1)	EA022470B1 (2)
ES (1)	ES2653847T3 (2)
IL (1)	IL227678B (2)
MA (1)	MA34909B1 (2)
MY (1)	MY162186A (2)
PE (1)	PE20141152A1 (2)
PH (1)	PH12013501528A1 (2)
PT (1)	PT2670765T (2)
SG (1)	SG192144A1 (2)
TN (1)	TN2013000321A1 (2)
TW (1)	TWI628188B (2)
UY (1)	UY33886A (2)
WO (1)	WO2012106190A1 (2)
ZA (1)	ZA201306546B (2)

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JP6186010B2 (ja) *	2013-02-06	2017-08-23	ブリストル−マイヤーズスクイブカンパニーＢｒｉｓｔｏｌ−ＭｙｅｒｓＳｑｕｉｂｂＣｏｍｐａｎｙ	Ｈｉｖ成熟阻害活性を有するｃ−１９修飾トリテルペノイド類
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UY36070A (es)	2014-04-11	2015-10-30	Bristol Myers Squibb Company Una Corporación Del Estado De Delaware	Triterpenoides con actividad inhibidora de la maduración de hiv
WO2015195776A1 (en)	2014-06-19	2015-12-23	Bristol-Myers Squibb Company	Betulinic acid derivatives with hiv maturation inhibitory activity
US9969767B2 (en)	2014-11-14	2018-05-15	VIIV Healthcare UK (No.5) Limited	Oxolupene derivatives
CN107250152A (zh) *	2014-11-14	2017-10-13	Viiv保健英国第五有限公司	C17‑芳基取代的桦木酸类似物
EP3283467A1 (en) *	2015-04-14	2018-02-21	VIIV Healthcare UK(No.4) Limited	Methods of producing an hiv maturation inhibitor
US20180194799A1 (en)	2015-07-28	2018-07-12	Glaxosmithkline Intellectual Property (No.2) Limited	Betuin derivatives for preventing or treating hiv infections
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KR20180054826A (ko)	2015-09-24	2018-05-24	글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드	Hiv 성숙 억제 활성을 갖는 화합물
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EP3478703A1 (en) *	2016-06-30	2019-05-08	ViiV Healthcare UK (No.5) Limited	Triterpenoid inhibitors of human immunodeficiency virus replication
WO2018044822A1 (en) *	2016-08-31	2018-03-08	Viiv Healthcare Company	Combinations and uses and treatments thereof
MX2020001412A (es)	2017-08-04	2020-08-03	Ardelyx Inc	Compuestos y métodos para tratar la hiperpotasemia.
JP6926939B2 (ja) *	2017-10-23	2021-08-25	東京エレクトロン株式会社	半導体装置の製造方法
JP6977474B2 (ja) *	2017-10-23	2021-12-08	東京エレクトロン株式会社	半導体装置の製造方法
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2012
- 2012-01-27 US US13/359,727 patent/US8846647B2/en active Active
- 2012-01-27 WO PCT/US2012/022852 patent/WO2012106190A1/en not_active Ceased
- 2012-01-27 PT PT127029478T patent/PT2670765T/pt unknown
- 2012-01-27 JP JP2013551362A patent/JP6001560B2/ja active Active
- 2012-01-27 MY MYPI2013701325A patent/MY162186A/en unknown
- 2012-01-27 PH PH1/2013/501528A patent/PH12013501528A1/en unknown
- 2012-01-27 PE PE2013001719A patent/PE20141152A1/es active IP Right Grant
- 2012-01-27 ES ES12702947.8T patent/ES2653847T3/es active Active
- 2012-01-27 BR BR112013019419A patent/BR112013019419A2/pt not_active Application Discontinuation
- 2012-01-27 SG SG2013056858A patent/SG192144A1/en unknown
- 2012-01-27 CN CN201280014966.XA patent/CN103429607B/zh active Active
- 2012-01-27 AU AU2012212509A patent/AU2012212509B2/en active Active
- 2012-01-27 CA CA2826113A patent/CA2826113C/en active Active
- 2012-01-27 EP EP12702947.8A patent/EP2670765B1/en active Active
- 2012-01-27 KR KR1020137023070A patent/KR101886467B1/ko active Active
- 2012-01-27 MA MA36183A patent/MA34909B1/fr unknown
- 2012-01-27 EA EA201391127A patent/EA022470B1/ru not_active IP Right Cessation
- 2012-01-31 TW TW101103140A patent/TWI628188B/zh active
- 2012-01-31 UY UY0001033886A patent/UY33886A/es not_active Application Discontinuation
- 2012-01-31 AR ARP120100314A patent/AR085053A1/es unknown
2013
- 2013-07-26 TN TNP2013000321A patent/TN2013000321A1/fr unknown
- 2013-07-28 IL IL227678A patent/IL227678B/en active IP Right Grant
- 2013-07-30 CL CL2013002185A patent/CL2013002185A1/es unknown
- 2013-08-27 CO CO13203030A patent/CO6751275A2/es unknown
- 2013-08-30 ZA ZA2013/06546A patent/ZA201306546B/en unknown
2014
- 2014-07-24 US US14/339,572 patent/US20140343000A1/en not_active Abandoned
2016
- 2016-02-04 US US15/015,741 patent/US20160151387A1/en not_active Abandoned

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