JP2014509837A5 - - Google Patents
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- JP2014509837A5 JP2014509837A5 JP2013547710A JP2013547710A JP2014509837A5 JP 2014509837 A5 JP2014509837 A5 JP 2014509837A5 JP 2013547710 A JP2013547710 A JP 2013547710A JP 2013547710 A JP2013547710 A JP 2013547710A JP 2014509837 A5 JP2014509837 A5 JP 2014509837A5
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- JP
- Japan
- Prior art keywords
- seq
- cdr
- variable region
- chain variable
- isolated antibody
- Prior art date
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Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201061428699P | 2010-12-30 | 2010-12-30 | |
| US61/428,699 | 2010-12-30 | ||
| US201161470382P | 2011-03-31 | 2011-03-31 | |
| US201161470406P | 2011-03-31 | 2011-03-31 | |
| US61/470,382 | 2011-03-31 | ||
| US61/470,406 | 2011-03-31 | ||
| US201161485104P | 2011-05-11 | 2011-05-11 | |
| US61/485,104 | 2011-05-11 | ||
| PCT/US2011/068235 WO2012092612A1 (en) | 2010-12-30 | 2011-12-30 | Anti-cd38 antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015172783A Division JP6425635B2 (ja) | 2010-12-30 | 2015-09-02 | 抗ｃｄ３８抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014509837A JP2014509837A (ja) | 2014-04-24 |
| JP2014509837A5 true JP2014509837A5 (2) | 2015-02-19 |
| JP5843884B2 JP5843884B2 (ja) | 2016-01-13 |
Family
ID=45498158
Family Applications (10)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013547713A Active JP6148984B2 (ja) | 2010-12-30 | 2011-12-30 | 結合抗ｃｄ３８抗体 |
| JP2013547710A Active JP5843884B2 (ja) | 2010-12-30 | 2011-12-30 | 抗ｃｄ３８抗体 |
| JP2015172783A Active JP6425635B2 (ja) | 2010-12-30 | 2015-09-02 | 抗ｃｄ３８抗体 |
| JP2015247967A Active JP6425644B2 (ja) | 2010-12-30 | 2015-12-18 | 結合抗ｃｄ３８抗体 |
| JP2017143106A Active JP6621447B2 (ja) | 2010-12-30 | 2017-07-24 | 抗ｃｄ３８抗体 |
| JP2017143107A Active JP6563446B2 (ja) | 2010-12-30 | 2017-07-24 | 結合抗ｃｄ３８抗体 |
| JP2019136165A Active JP6766233B2 (ja) | 2010-12-30 | 2019-07-24 | 結合抗ｃｄ３８抗体 |
| JP2019174782A Active JP6840813B2 (ja) | 2010-12-30 | 2019-09-25 | 抗ｃｄ３８抗体 |
| JP2020155609A Active JP7096301B2 (ja) | 2010-12-30 | 2020-09-16 | 結合抗ｃｄ３８抗体 |
| JP2021023741A Active JP7315598B2 (ja) | 2010-12-30 | 2021-02-17 | 抗ｃｄ３８抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013547713A Active JP6148984B2 (ja) | 2010-12-30 | 2011-12-30 | 結合抗ｃｄ３８抗体 |
Family Applications After (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015172783A Active JP6425635B2 (ja) | 2010-12-30 | 2015-09-02 | 抗ｃｄ３８抗体 |
| JP2015247967A Active JP6425644B2 (ja) | 2010-12-30 | 2015-12-18 | 結合抗ｃｄ３８抗体 |
| JP2017143106A Active JP6621447B2 (ja) | 2010-12-30 | 2017-07-24 | 抗ｃｄ３８抗体 |
| JP2017143107A Active JP6563446B2 (ja) | 2010-12-30 | 2017-07-24 | 結合抗ｃｄ３８抗体 |
| JP2019136165A Active JP6766233B2 (ja) | 2010-12-30 | 2019-07-24 | 結合抗ｃｄ３８抗体 |
| JP2019174782A Active JP6840813B2 (ja) | 2010-12-30 | 2019-09-25 | 抗ｃｄ３８抗体 |
| JP2020155609A Active JP7096301B2 (ja) | 2010-12-30 | 2020-09-16 | 結合抗ｃｄ３８抗体 |
| JP2021023741A Active JP7315598B2 (ja) | 2010-12-30 | 2021-02-17 | 抗ｃｄ３８抗体 |
Country Status (38)
| Country | Link |
|---|---|
| US (11) | US8362211B2 (2) |
| EP (6) | EP3284755B1 (2) |
| JP (10) | JP6148984B2 (2) |
| KR (5) | KR102070326B1 (2) |
| CN (4) | CN107365385A (2) |
| AR (1) | AR084747A1 (2) |
| AU (3) | AU2011351921B2 (2) |
| BR (1) | BR112013017009B1 (2) |
| CA (1) | CA2822061C (2) |
| CO (1) | CO6761368A2 (2) |
| CR (1) | CR20130313A (2) |
| CY (3) | CY1122161T1 (2) |
| DK (3) | DK2658871T3 (2) |
| EA (2) | EA201791186A1 (2) |
| EC (1) | ECSP13012794A (2) |
| ES (3) | ES2841299T3 (2) |
| GE (1) | GEP20166493B (2) |
| HR (3) | HRP20181245T1 (2) |
| HU (3) | HUE052906T2 (2) |
| IL (1) | IL226973A (2) |
| JO (2) | JOP20210044A1 (2) |
| LT (3) | LT2658870T (2) |
| MA (1) | MA34763B1 (2) |
| MX (2) | MX350903B (2) |
| MY (1) | MY160499A (2) |
| NZ (2) | NZ705848A (2) |
| PE (1) | PE20140247A1 (2) |
| PL (3) | PL3284754T3 (2) |
| PT (3) | PT3284754T (2) |
| RS (3) | RS57526B1 (2) |
| SG (1) | SG191211A1 (2) |
| SI (3) | SI2658871T1 (2) |
| SM (2) | SMT201800405T1 (2) |
| TR (1) | TR201808709T4 (2) |
| TW (1) | TWI564304B (2) |
| UY (1) | UY33850A (2) |
| WO (2) | WO2012092612A1 (2) |
| ZA (1) | ZA201304696B (2) |
Families Citing this family (195)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005235811B2 (en) | 2004-02-06 | 2011-11-03 | Morphosys Ag | Anti-CD38 human antibodies and uses therefor |
| US9200061B2 (en) * | 2004-02-06 | 2015-12-01 | Morpho Sys AG | Generation and profiling of fully human HuCAL gold®-derived therapeutic antibodies specific for human CD3i |
| CA2625681C (en) | 2005-10-12 | 2016-08-02 | Morphosys Ag | Generation and profiling of fully human hucal gold-derived therapeutic antibodies specific for human cd38 |
| EP1914242A1 (en) * | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
| DK2621531T3 (en) | 2010-09-27 | 2017-02-27 | Morphosys Ag | ANTI-CD38 ANTIBODY AND LENALIDOMIDE OR BORTEZOMIB FOR TREATMENT OF MULTIPLE MYELOM AND NHL |
| JOP20210044A1 (ar) * | 2010-12-30 | 2017-06-16 | Takeda Pharmaceuticals Co | الأجسام المضادة لـ cd38 |
| EP3559049B1 (en) | 2011-10-28 | 2025-06-11 | Teva Pharmaceuticals Australia Pty Ltd | Polypeptide constructs and uses thereof |
| JP6224586B2 (ja) | 2012-07-10 | 2017-11-01 | 武田薬品工業株式会社 | 注射用製剤 |
| MX368288B (es) | 2012-09-25 | 2019-09-27 | Morphosys Ag | Una combinación de anticuerpos anti-cd38 y melfalán para usarse en el tratamiento de mieloma múltiple. |
| US10342869B2 (en) | 2012-12-07 | 2019-07-09 | The Regents Of The University Of California | Compositions comprising anti-CD38 antibodies and lenalidomide |
| UA118255C2 (uk) * | 2012-12-07 | 2018-12-26 | Санофі | Композиція, яка містить антитіло до cd38 і леналідомід |
| MX368259B (es) * | 2013-04-16 | 2019-09-25 | Genentech Inc | Variantes de pertuzumab y su evaluacion. |
| BR112015027313A2 (pt) * | 2013-04-29 | 2017-09-26 | Teva Pharmaceuticals Australia Pty Ltd | anticorpos anti-cd38 e fusões ao interferon alfa-2b atenuado |
| US11117975B2 (en) | 2013-04-29 | 2021-09-14 | Teva Pharmaceuticals Australia Pty Ltd | Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B |
| US20150118251A1 (en) * | 2013-10-31 | 2015-04-30 | Sanofi | Specific anti-cd38 antibodies for treating human cancers |
| JP2016538275A (ja) | 2013-11-04 | 2016-12-08 | グレンマーク ファーマシューティカルズ， エセ．アー． | Ｔ細胞再標的化ヘテロ二量体免疫グロブリン（ｈｅｔｅｒｏ−ｄｉｍｅｒｉｃ ｉｍｍｕｎｏｇｌｏｂｕｌｉｎ）の製造 |
| JP2017506640A (ja) * | 2014-02-14 | 2017-03-09 | セントローズ， エルエルシー | 細胞外標的化薬物共役体 |
| US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
| US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
| US20170335281A1 (en) | 2014-03-15 | 2017-11-23 | Novartis Ag | Treatment of cancer using chimeric antigen receptor |
| UA119352C2 (uk) | 2014-05-01 | 2019-06-10 | Тева Фармасьютикалз Острейліа Пті Лтд | Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину |
| KR20170032406A (ko) | 2014-07-15 | 2017-03-22 | 주노 쎄러퓨티크스 인코퍼레이티드 | 입양 세포 치료를 위한 조작된 세포 |
| JP2017528433A (ja) | 2014-07-21 | 2017-09-28 | ノバルティス アーゲー | 低い免疫増強用量のｍＴＯＲ阻害剤とＣＡＲの組み合わせ |
| PH12017500442B1 (en) | 2014-09-09 | 2023-05-24 | Janssen Biotech Inc | Combination therapies with anti-cd38 antibodies |
| US10544199B2 (en) | 2014-10-29 | 2020-01-28 | Teva Pharmaceuticals Australia Pty Ltd | Interferon alpha 2B variants |
| MA40894A (fr) * | 2014-11-04 | 2017-09-12 | Glenmark Pharmaceuticals Sa | Immunoglobulines hétéro-dimères reciblant des lymphocytes t cd3/cd38 et leurs procédés de production |
| US11773166B2 (en) | 2014-11-04 | 2023-10-03 | Ichnos Sciences SA | CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production |
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| EA201792546A1 (ru) | 2015-05-20 | 2018-04-30 | Янссен Байотек, Инк. | Антитела к cd38 для лечения амилоидоза легких цепей и прочих cd38-положительных гематологических злокачественных опухолей |
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