JP2017043632A5 - - Google Patents
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- JP2017043632A5 JP2017043632A5 JP2016225290A JP2016225290A JP2017043632A5 JP 2017043632 A5 JP2017043632 A5 JP 2017043632A5 JP 2016225290 A JP2016225290 A JP 2016225290A JP 2016225290 A JP2016225290 A JP 2016225290A JP 2017043632 A5 JP2017043632 A5 JP 2017043632A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- factor
- inhibitor
- amino acid
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97634307P | 2007-09-28 | 2007-09-28 | |
| US60/976,343 | 2007-09-28 | ||
| US9057408P | 2008-08-20 | 2008-08-20 | |
| US61/090,574 | 2008-08-20 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014166333A Division JP6047127B2 (ja) | 2007-09-28 | 2014-08-19 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018033229A Division JP2018100290A (ja) | 2007-09-28 | 2018-02-27 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017043632A JP2017043632A (ja) | 2017-03-02 |
| JP2017043632A5 true JP2017043632A5 (2) | 2017-07-27 |
| JP6300885B2 JP6300885B2 (ja) | 2018-03-28 |
Family
ID=40481812
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010527220A Active JP5637561B2 (ja) | 2007-09-28 | 2008-09-26 | 第Ｘａ因子阻害剤に対する解毒剤およびその使用の方法 |
| JP2014166333A Active JP6047127B2 (ja) | 2007-09-28 | 2014-08-19 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
| JP2016225290A Active JP6300885B2 (ja) | 2007-09-28 | 2016-11-18 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
| JP2018033229A Pending JP2018100290A (ja) | 2007-09-28 | 2018-02-27 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
| JP2020042919A Pending JP2020109113A (ja) | 2007-09-28 | 2020-03-12 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
| JP2022121451A Pending JP2022153574A (ja) | 2007-09-28 | 2022-07-29 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
| JP2025008426A Pending JP2025063249A (ja) | 2007-09-28 | 2025-01-21 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010527220A Active JP5637561B2 (ja) | 2007-09-28 | 2008-09-26 | 第Ｘａ因子阻害剤に対する解毒剤およびその使用の方法 |
| JP2014166333A Active JP6047127B2 (ja) | 2007-09-28 | 2014-08-19 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018033229A Pending JP2018100290A (ja) | 2007-09-28 | 2018-02-27 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
| JP2020042919A Pending JP2020109113A (ja) | 2007-09-28 | 2020-03-12 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
| JP2022121451A Pending JP2022153574A (ja) | 2007-09-28 | 2022-07-29 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
| JP2025008426A Pending JP2025063249A (ja) | 2007-09-28 | 2025-01-21 | 第Ｘａ因子阻害剤に対する抗体およびその使用の方法 |
Country Status (26)
| Country | Link |
|---|---|
| US (8) | US8153590B2 (2) |
| EP (4) | EP2915564B1 (2) |
| JP (7) | JP5637561B2 (2) |
| KR (4) | KR20170100071A (2) |
| CN (4) | CN102533702A (2) |
| AU (7) | AU2008304192B9 (2) |
| BR (2) | BRPI0816837B1 (2) |
| CA (1) | CA2697583C (2) |
| CY (3) | CY1118482T1 (2) |
| DK (3) | DK3078743T3 (2) |
| ES (3) | ES2597436T3 (2) |
| FR (1) | FR20C1045I2 (2) |
| HR (2) | HRP20161255T1 (2) |
| HU (4) | HUE052423T2 (2) |
| IL (4) | IL203993A (2) |
| LT (3) | LT2193196T (2) |
| MX (1) | MX2010003095A (2) |
| NL (1) | NL301063I2 (2) |
| NO (2) | NO2019040I1 (2) |
| NZ (1) | NZ583944A (2) |
| PL (3) | PL3078743T3 (2) |
| PT (3) | PT3078743T (2) |
| SG (1) | SG185263A1 (2) |
| SI (3) | SI2915564T1 (2) |
| WO (1) | WO2009042962A2 (2) |
| ZA (2) | ZA201002039B (2) |
Families Citing this family (61)
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| EP2915564B1 (en) | 2007-09-28 | 2020-11-04 | Portola Pharmaceuticals, Inc. | Antidotes for factor XA inhibitors and methods of using the same |
| MX2011004907A (es) | 2008-11-14 | 2011-07-29 | Portola Pharm Inc | Antidotos para inhibidores del factor xa y metodos para el uso de los mismos en combinacion con agentes de coagulacion de sangre. |
| KR101792032B1 (ko) * | 2008-12-19 | 2017-11-02 | 백스터 인터내셔널 인코포레이티드 | Ｔｆｐｉ 억제제 및 사용 방법 |
| EP3121271B1 (en) * | 2009-03-30 | 2019-07-24 | Portola Pharmaceuticals, Inc. | Antidotes for factor xa inhibitors and methods of using the same |
| ES2605801T3 (es) * | 2009-07-15 | 2017-03-16 | Portola Pharmaceuticals, Inc. | Formulación de dosis unitaria de antídoto para inhibidores del factor Xa para su uso en la prevención de la hemorragia |
| GB0916576D0 (en) * | 2009-09-22 | 2009-10-28 | Malmsten Nils M | Polypeptides and uses thereof |
| ES2620421T3 (es) * | 2009-10-30 | 2017-06-28 | Senova Gesellschaft für Biowissenschaft und Technik mbH | Peptidasas acopladas a polímero |
| US8742120B2 (en) * | 2009-12-17 | 2014-06-03 | Millennium Pharmaceuticals, Inc. | Methods of preparing factor xa inhibitors and salts thereof |
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| FR2972114B1 (fr) * | 2011-03-01 | 2013-03-15 | Univ Grenoble 1 | Un nouveau leurre moleculaire procoagulant pour le traitement des hemophiles a ou b avec ou sans inhibiteur |
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| CA2898975C (en) * | 2013-01-24 | 2021-06-15 | Portola Pharmaceuticals, Inc. | Inhibition of tissue factor pathway inhibitor with factor xa derivatives |
| ES2761730T3 (es) | 2013-01-31 | 2020-05-20 | Pfizer | Composiciones y procedimientos para contrarrestar la inhibición del factor Xa |
| FR3007410B1 (fr) * | 2013-06-21 | 2016-05-27 | Lab Francais Du Fractionnement | Facteur x depourvu de domaine gla |
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| EP3063170A4 (en) * | 2013-11-01 | 2017-06-28 | The Children's Hospital of Philadelphia | Compositions and methods for increasing the half-life of factor xa |
| EA202190813A1 (ru) * | 2014-05-26 | 2021-12-31 | Академиш Зикенхёйс Лейден | Прогемостатические белки для лечения кровотечений |
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| US10676731B2 (en) | 2014-08-19 | 2020-06-09 | The Children's Hospital Of Philadelphia | Compositions and methods for modulating factor IX function |
| EP3750556A1 (en) | 2014-08-20 | 2020-12-16 | Portola Pharmaceuticals, Inc. | Lyophilized formulations for factor xa antidote |
| CN105030703B (zh) * | 2015-06-23 | 2018-03-23 | 上海旭东海普药业有限公司 | 一种防治疗栓塞性疾病的利伐沙班片及其制备方法 |
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| AU2017383232B2 (en) | 2016-12-23 | 2024-09-12 | Novartis Ag | Factor XI antibodies and methods of use |
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| JP7841846B2 (ja) | 2017-11-15 | 2026-04-07 | ノヴォ ノルディスク アー／エス | Ｆｘ活性化を促進する第ｘ因子結合剤 |
| JP2021527435A (ja) * | 2018-06-19 | 2021-10-14 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 第Ｘａ因子阻害剤に対する解毒剤 |
| WO2020034989A1 (zh) * | 2018-08-14 | 2020-02-20 | 江苏恒瑞医药股份有限公司 | 一种可注射的药物组合物及其制备方法 |
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| JP7853226B2 (ja) * | 2020-06-16 | 2026-04-28 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | アンデキサネットの効力を試験するための方法 |
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| US12073926B2 (en) | 2020-09-21 | 2024-08-27 | Instrumentation Laboratory Company | Detecting and monitoring oral anticoagulants or intravenous direct thrombin inhibitors in a blood sample |
| CN113484386B (zh) * | 2021-05-21 | 2024-02-13 | 郑州轻工业大学 | 一种金属聚酞菁纳米材料的制备方法及其应用，适配体传感器及其制备方法 |
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