JP2017512759A5 - - Google Patents
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- JP2017512759A5 JP2017512759A5 JP2016554855A JP2016554855A JP2017512759A5 JP 2017512759 A5 JP2017512759 A5 JP 2017512759A5 JP 2016554855 A JP2016554855 A JP 2016554855A JP 2016554855 A JP2016554855 A JP 2016554855A JP 2017512759 A5 JP2017512759 A5 JP 2017512759A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- cancer
- amino acid
- homologous
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461977824P | 2014-04-10 | 2014-04-10 | |
| US61/977,824 | 2014-04-10 | ||
| US201462057381P | 2014-09-30 | 2014-09-30 | |
| US62/057,381 | 2014-09-30 | ||
| PCT/US2015/025305 WO2015157629A2 (en) | 2014-04-10 | 2015-04-10 | Antibodies, pharmaceutical compositions and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017512759A JP2017512759A (ja) | 2017-05-25 |
| JP2017512759A5 true JP2017512759A5 (2) | 2019-06-27 |
Family
ID=54288553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016554855A Pending JP2017512759A (ja) | 2014-04-10 | 2015-04-10 | 抗体、前記抗体を産生するハイブリドーマ、前記抗体を含む薬学的組成物及びその用途 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US9902779B2 (2) |
| EP (2) | EP3129048B1 (2) |
| JP (1) | JP2017512759A (2) |
| KR (1) | KR101966408B1 (2) |
| CN (2) | CN112390887B (2) |
| AU (2) | AU2015243246B2 (2) |
| BR (1) | BR112016020009A2 (2) |
| CA (2) | CA2941029C (2) |
| CL (1) | CL2016002569A1 (2) |
| ES (1) | ES2772817T3 (2) |
| IL (2) | IL246837B (2) |
| PH (1) | PH12016501976A1 (2) |
| RU (1) | RU2016138744A (2) |
| SG (1) | SG11201607258SA (2) |
| TW (3) | TWI697503B (2) |
| WO (1) | WO2015157629A2 (2) |
| ZA (1) | ZA201605175B (2) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014391422A1 (en) | 2013-09-17 | 2015-12-17 | Obi Pharma, Inc. | Compositions of a carbohydrate vaccine for inducing immune responses and uses thereof in cancer treatment |
| EP3119424A4 (en) | 2014-03-19 | 2017-09-13 | MacKay Medical Foundation the Presbyterian Church in Taiwan MacKay Memorial Hospital | Immunogenic glycopeptides, composition comprising the glycopeptides and use thereof |
| CA2941029C (en) | 2014-04-10 | 2021-02-16 | Obi Pharma Inc. | Antibodies, pharmaceutical compositions and uses thereof |
| KR20180050339A (ko) | 2015-09-04 | 2018-05-14 | 오비아이 파머 인코퍼레이티드 | 글리칸 어레이 및 사용 방법 |
| KR20180077181A (ko) | 2015-10-07 | 2018-07-06 | 오비아이 파머 인코퍼레이티드 | 신규한 탄수화물 항체, 약제학적 조성물 및 이들의 용도 |
| AU2017239637A1 (en) | 2016-03-29 | 2018-11-15 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
| US10980894B2 (en) | 2016-03-29 | 2021-04-20 | Obi Pharma, Inc. | Antibodies, pharmaceutical compositions and methods |
| CN109379889A (zh) | 2016-04-22 | 2019-02-22 | 台湾浩鼎生技股份有限公司 | 通过经由globo系列抗原的免疫激活或免疫调节的癌症免疫疗法 |
| GB201612317D0 (en) * | 2016-07-15 | 2016-08-31 | Philogen Spa | Antibody compositions |
| KR20230117482A (ko) | 2016-07-27 | 2023-08-08 | 오비아이 파머 인코퍼레이티드 | 면역원성/치료 글리칸 조성물 및 그의 용도 |
| WO2018023121A1 (en) | 2016-07-29 | 2018-02-01 | Obi Pharma, Inc. | Human antibodies, pharmaceutical compositions and methods |
| TWI822055B (zh) * | 2016-11-21 | 2023-11-11 | 台灣浩鼎生技股份有限公司 | 共軛生物分子、醫藥組成物及方法 |
| EP3630182A4 (en) * | 2017-05-24 | 2021-02-24 | Development Center for Biotechnology | HUMANIZED ANTIBODIES TO GLOBO H AND THEIR USE IN CANCER TREATMENT |
| EP3765031A4 (en) | 2018-03-14 | 2022-03-23 | Memorial Sloan Kettering Cancer Center | ANTI-POLYSIAL ACID ANTIBODIES AND USES THEREOF |
| WO2019232519A1 (en) * | 2018-06-01 | 2019-12-05 | Obi Pharma, Inc. | Combination therapy by using anti-globo h or anti-ssea-4 antibody with anti-negative immune check points antibody |
| WO2020006176A1 (en) | 2018-06-27 | 2020-01-02 | Obi Pharma, Inc. | Glycosynthase variants for glycoprotein engineering and methods of use |
| EP3946630A4 (en) * | 2019-03-28 | 2023-09-27 | OBI Pharma, Inc. | COMPANIONARY DIAGNOSTIC TEST FOR CANCER THERAPY IN CONNECTION WITH GLOBO-H |
| CA3204922A1 (en) * | 2021-02-09 | 2022-08-18 | Ming-Tain Lai | Globo series antigens-binding chimeric antigen receptors and uses thereof |
| WO2026052782A1 (en) | 2024-09-06 | 2026-03-12 | Tacalyx Gmbh | Anti-globo h antibodies |
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| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| JPS61134325A (ja) | 1984-12-04 | 1986-06-21 | Teijin Ltd | ハイブリツド抗体遺伝子の発現方法 |
| JPS63501765A (ja) | 1985-11-01 | 1988-07-21 | インタ−ナショナル、ジェネティック、エンジニアリング インコ−ポレ−テッド | 抗体遺伝子のモジュ−ル組立体、それにより産生された抗体及び用途 |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| NZ230747A (en) | 1988-09-30 | 1992-05-26 | Bror Morein | Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| EP0519596B1 (en) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
| AU665025B2 (en) | 1991-09-23 | 1995-12-14 | Cambridge Antibody Technology Limited | Production of chimeric antibodies - a combinatorial approach |
| AUPM873294A0 (en) | 1994-10-12 | 1994-11-03 | Csl Limited | Saponin preparations and use thereof in iscoms |
| AUPO517897A0 (en) | 1997-02-19 | 1997-04-11 | Csl Limited | Chelating immunostimulating complexes |
| AUPP807399A0 (en) | 1999-01-08 | 1999-02-04 | Csl Limited | Improved immunogenic lhrh composition and methods relating thereto |
| WO2000048630A1 (en) | 1999-02-17 | 2000-08-24 | Csl Limited | Immunogenic complexes and methods relating thereto |
| CN1423700A (zh) | 2000-03-24 | 2003-06-11 | 麦克美特股份公司 | 含有针对nkg2d受体复合物的表位的结合位点的多功能多肽 |
| CU23007A1 (es) * | 2001-04-06 | 2004-12-17 | Ct De Inmunologia Molecular Ct De Inmunologia Mole | Combinaciones inmunoterapéuticas para el tratamiencombinaciones inmunoterapéuticas para el tratamiento de tumores que sobre-expresan gangliósidos to de tumores que sobre-expresan gangliósidos |
| DE60124912T2 (de) * | 2001-09-14 | 2007-06-14 | Affimed Therapeutics Ag | Multimerische, einzelkettige, Tandem-Fv-Antikörper |
| BR0107262B1 (pt) | 2001-12-17 | 2014-04-22 | Da Fonseca Clovis Orlando Pereira | Composição farmacêutica inalatória |
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| JP4335130B2 (ja) * | 2002-04-30 | 2009-09-30 | 協和発酵キリン株式会社 | ヒトインスリン様成長因子に対する抗体 |
| DE60334453D1 (de) * | 2002-05-30 | 2010-11-18 | Macrogenics Inc | Cd16a bindungsproteine und verwendung zur behandlung von immunkrankheiten |
| AT413486B (de) * | 2002-07-03 | 2006-03-15 | Igeneon Krebs Immuntherapie | Verwendung eines antikörpers gerichtet gegen lewis-antigene |
| LT2857418T (lt) | 2004-02-06 | 2017-09-25 | University Of Massachusetts | Antikūnai prieš clostridium difficile toksinus ir jų panaudojimas |
| EP2287195B1 (en) * | 2004-07-01 | 2019-05-15 | Novo Nordisk A/S | Pan-kir2dl nk-receptor antibodies and their use in diagnostik and therapy |
| KR100958505B1 (ko) | 2004-07-18 | 2010-05-17 | 씨에스엘 리미티드 | 면역자극 복합체 및 향상된 인터페론-감마 반응을 유도하기위한 올리고뉴클레오티드 제제 |
| CA2574090A1 (en) | 2004-07-18 | 2006-12-21 | Coley Pharmaceutical Group, Ltd. | Methods and compositions for inducing innate immune responses |
| BRPI0519596B1 (pt) * | 2004-12-21 | 2022-01-18 | Astrazeneca Ab | Agente de ligação alvejado, anticorpo monoclonal que se liga a angiopoietina-2, molécula de ácido nucleico, vetor, e, uso do agente de ligação alvejado |
| AU2006211037B2 (en) * | 2005-02-07 | 2012-05-24 | Roche Glycart Ag | Antigen binding molecules that bind EGFR, vectors encoding same, and uses thereof |
| AU2006230099B2 (en) * | 2005-03-25 | 2012-04-19 | Gitr, Inc. | GITR binding molecules and uses therefor |
| CL2007002668A1 (es) * | 2006-09-20 | 2008-05-09 | Amgen Inc | Proteina de union a antigeno que se une al receptor de glucagon humano; acido nucleico que la codifica; metodo de produccion; composicion farmaceutica que la comprende; y su uso para tratar o prevenir la diabetes tipo 2. |
| EP1920781B1 (en) | 2006-11-10 | 2015-03-04 | Glycotope GmbH | Compositions comprising a core-1 positive microorganism and their use for the treatment or prophylaxis of tumors |
| US20100145032A1 (en) * | 2007-01-18 | 2010-06-10 | Suomen Punainen Risti, Veripalelu | Novel carbohydrate profile compositions from human cells and methods for analysis and modification thereof |
| CN102065868A (zh) | 2008-06-16 | 2011-05-18 | 中央研究院 | 诱发对于Globo H及SSEA3的特异免疫反应的组合物以及其在癌症治疗中的用途 |
| ES2477549T3 (es) | 2008-06-16 | 2014-07-17 | Academia Sinica | Diagnóstico del cáncer según la concentración de anticuerpos contra Globo H y sus fragmentos |
| TWI392502B (zh) * | 2009-06-16 | 2013-04-11 | Academia Sinica | 聚己醣抗原及含新穎醣脂質佐劑之相關抗癌疫苗 |
| ES2624835T3 (es) * | 2009-08-06 | 2017-07-17 | Immunas Pharma, Inc. | Anticuerpos que se unen específicamente a los oligómeros A beta y uso de los mismos |
| CN102884085B (zh) | 2010-04-09 | 2016-08-03 | Aveo制药公司 | 抗erbb3抗体 |
| CN103459600B (zh) * | 2010-07-01 | 2016-10-19 | 帝斯曼知识产权资产管理有限公司 | 用于生产感兴趣的化合物的方法 |
| US8999343B2 (en) * | 2010-08-16 | 2015-04-07 | Amgen Inc. | Antibodies that bind myostatin, compositions and methods |
| WO2012088094A2 (en) * | 2010-12-21 | 2012-06-28 | Abbott Laboratories | Il-1 binding proteins |
| EP2497782A1 (en) * | 2011-03-08 | 2012-09-12 | Alzinova AB | Anti oligomer antibodies and uses thereof |
| US9828635B2 (en) | 2011-10-06 | 2017-11-28 | Aveo Pharmaceuticals, Inc. | Predicting tumor response to anti-ERBB3 antibodies |
| PE20190658A1 (es) | 2012-02-24 | 2019-05-08 | Abbvie Stemcentrx Llc | Moduladores y metodos de empleo novedosos |
| CA2937123A1 (en) | 2014-01-16 | 2015-07-23 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| EP3119424A4 (en) | 2014-03-19 | 2017-09-13 | MacKay Medical Foundation the Presbyterian Church in Taiwan MacKay Memorial Hospital | Immunogenic glycopeptides, composition comprising the glycopeptides and use thereof |
| CA2941029C (en) | 2014-04-10 | 2021-02-16 | Obi Pharma Inc. | Antibodies, pharmaceutical compositions and uses thereof |
-
2015
- 2015-04-10 CA CA2941029A patent/CA2941029C/en active Active
- 2015-04-10 TW TW106128654A patent/TWI697503B/zh active
- 2015-04-10 TW TW104111557A patent/TWI609886B/zh active
- 2015-04-10 SG SG11201607258SA patent/SG11201607258SA/en unknown
- 2015-04-10 CA CA3104268A patent/CA3104268A1/en not_active Abandoned
- 2015-04-10 KR KR1020167024072A patent/KR101966408B1/ko not_active Expired - Fee Related
- 2015-04-10 RU RU2016138744A patent/RU2016138744A/ru not_active Application Discontinuation
- 2015-04-10 EP EP15777370.6A patent/EP3129048B1/en active Active
- 2015-04-10 CN CN202011258954.4A patent/CN112390887B/zh not_active Expired - Fee Related
- 2015-04-10 TW TW106128651A patent/TWI695013B/zh not_active IP Right Cessation
- 2015-04-10 ES ES15777370T patent/ES2772817T3/es active Active
- 2015-04-10 US US15/303,132 patent/US9902779B2/en not_active Expired - Fee Related
- 2015-04-10 EP EP20151337.1A patent/EP3662928A1/en not_active Withdrawn
- 2015-04-10 JP JP2016554855A patent/JP2017512759A/ja active Pending
- 2015-04-10 AU AU2015243246A patent/AU2015243246B2/en not_active Ceased
- 2015-04-10 BR BR112016020009A patent/BR112016020009A2/pt not_active IP Right Cessation
- 2015-04-10 CN CN201580011286.6A patent/CN106456727B/zh not_active Expired - Fee Related
- 2015-04-10 WO PCT/US2015/025305 patent/WO2015157629A2/en not_active Ceased
-
2016
- 2016-07-19 IL IL246837A patent/IL246837B/en active IP Right Grant
- 2016-07-25 ZA ZA2016/05175A patent/ZA201605175B/en unknown
- 2016-10-04 PH PH12016501976A patent/PH12016501976A1/en unknown
- 2016-10-07 CL CL2016002569A patent/CL2016002569A1/es unknown
-
2017
- 2017-11-28 US US15/824,733 patent/US10815307B2/en active Active
-
2018
- 2018-10-26 AU AU2018253589A patent/AU2018253589B2/en not_active Ceased
-
2020
- 2020-08-13 IL IL276695A patent/IL276695B/en unknown
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