JP2018522041A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2018522041A5 JP2018522041A5 JP2018505476A JP2018505476A JP2018522041A5 JP 2018522041 A5 JP2018522041 A5 JP 2018522041A5 JP 2018505476 A JP2018505476 A JP 2018505476A JP 2018505476 A JP2018505476 A JP 2018505476A JP 2018522041 A5 JP2018522041 A5 JP 2018522041A5
- Authority
- JP
- Japan
- Prior art keywords
- brachyury
- yeast
- immunotherapy composition
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562200497P | 2015-08-03 | 2015-08-03 | |
| US62/200,497 | 2015-08-03 | ||
| PCT/US2016/044977 WO2017023840A1 (en) | 2015-08-03 | 2016-08-01 | Modified yeast-brachyury immunotherapeutic compositions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018522041A JP2018522041A (ja) | 2018-08-09 |
| JP2018522041A5 true JP2018522041A5 (2) | 2019-09-12 |
| JP6789283B2 JP6789283B2 (ja) | 2020-11-25 |
Family
ID=56618277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018505476A Active JP6789283B2 (ja) | 2015-08-03 | 2016-08-01 | 改変酵母−ブラキュリー免疫療法組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11065313B2 (2) |
| EP (1) | EP3331552B1 (2) |
| JP (1) | JP6789283B2 (2) |
| KR (1) | KR102833272B1 (2) |
| CN (1) | CN108348586B (2) |
| AU (1) | AU2016303525B2 (2) |
| CA (1) | CA2994272C (2) |
| HK (1) | HK1249431A1 (2) |
| IL (1) | IL257208B (2) |
| TW (1) | TWI748957B (2) |
| WO (1) | WO2017023840A1 (2) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014265873B2 (en) | 2013-03-19 | 2019-01-17 | Globeimmune, Inc. | Yeast-based immunotherapy for chordoma |
| CA2948803A1 (en) * | 2014-04-11 | 2015-10-15 | Globeimmune, Inc. | Yeast-based immunotherapy and type i interferon sensitivity |
| EP4137150A1 (en) * | 2015-08-03 | 2023-02-22 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use |
| CN119818663A (zh) * | 2018-05-15 | 2025-04-15 | 全球免疫公司 | 用于诱导细胞免疫应答的重组酵母裂解物 |
| EP3886869A4 (en) | 2018-11-28 | 2022-07-06 | Forty Seven, Inc. | GENETICALLY MODIFIED ABLATION-RESISTANT HSPCS |
| WO2022187963A1 (en) * | 2021-03-10 | 2022-09-15 | Provincial Health Services Authority | Immunotherapy agents targeting brachyury and methods of using same |
| EP4489774A4 (en) * | 2022-03-08 | 2026-04-29 | Immunitybio Inc | YEAST-BASED VACCINE INJECTED INTRATUMORALLY |
| EP4516807A1 (en) | 2023-08-28 | 2025-03-05 | Consorcio Centro de Investigación Biomédica en Red | Compositions for use in a method of providing improved hematopoietic stem cell engraftment |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2486400B1 (fr) | 1980-07-09 | 1986-05-30 | Univablot | Medicaments a base de levures ou de leurs extraits insolubles |
| NZ199722A (en) | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
| US4775622A (en) | 1982-03-08 | 1988-10-04 | Genentech, Inc. | Expression, processing and secretion of heterologous protein by yeast |
| US5310654A (en) | 1985-07-31 | 1994-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Method for determining virulence of Yersinia |
| US5234830A (en) | 1988-02-03 | 1993-08-10 | Suntory Limited | DNA encoding a KEX2 endoprotease without a C-terminal hydrophobic region |
| IL95019A0 (en) | 1989-08-09 | 1991-06-10 | Mycogen Corp | Process for encapsulation of biologicals |
| US5830463A (en) | 1993-07-07 | 1998-11-03 | University Technology Corporation | Yeast-based delivery vehicles |
| US5413914A (en) | 1993-07-07 | 1995-05-09 | The Regents Of The University Of Colorado | Yeast assay to identify inhibitors of dibasic amino acid processing endoproteases |
| US5858378A (en) | 1996-05-02 | 1999-01-12 | Galagen, Inc. | Pharmaceutical composition comprising cryptosporidium parvum oocysts antigen and whole cell candida species antigen |
| EP1037643B1 (en) | 1997-10-10 | 2003-12-03 | Meyer Pharmaceuticals, LLC | Cancer immunotherapy using allostimulated cells in a multiple sequential implantation strategy |
| US5948646A (en) | 1997-12-11 | 1999-09-07 | Fordham University | Methods for preparation of vaccines against cancer comprising heat shock protein-peptide complexes |
| US20020044948A1 (en) | 2000-03-15 | 2002-04-18 | Samir Khleif | Methods and compositions for co-stimulation of immunological responses to peptide antigens |
| AU1951001A (en) | 2000-04-06 | 2001-09-17 | Panacea Pharm Llc | Microbial delivery system |
| AU2002225681A1 (en) | 2000-11-15 | 2002-05-27 | Globe Immune, Inc. | Yeast-dentritic cell vaccines and uses thereof |
| KR101455222B1 (ko) | 2002-12-16 | 2014-10-31 | 글로브이뮨 | 면역 요법으로서의 효모계 백신 |
| US7439042B2 (en) | 2002-12-16 | 2008-10-21 | Globeimmune, Inc. | Yeast-based therapeutic for chronic hepatitis C infection |
| US20060009404A1 (en) | 2004-07-09 | 2006-01-12 | Williams Jason R | Tumor ablation in combination with pharmaceutical compositions |
| SG163572A1 (en) | 2005-07-11 | 2010-08-30 | Globeimmune Inc | Compositions and methods for eliciting an immune response to escape mutants of targeted therapies |
| US20070172503A1 (en) | 2005-12-13 | 2007-07-26 | Mycologics,Inc. | Compositions and Methods to Elicit Immune Responses Against Pathogenic Organisms Using Yeast Based Vaccines |
| US7736642B2 (en) | 2006-02-02 | 2010-06-15 | Globeimmune, Inc. | Yeast-based vaccine for inducing an immune response |
| BRPI0709340A2 (pt) | 2006-03-27 | 2013-04-16 | Globeimmune, Inc. | mutaÇço ras e composiÇÕes e mÉtodos de uso da mesma |
| WO2008097863A2 (en) | 2007-02-02 | 2008-08-14 | Globeimmune, Inc. | Methods for producing yeast-based vaccines |
| WO2008106551A2 (en) | 2007-02-28 | 2008-09-04 | The Govt. Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health & Human Serv. | Brachyury polypeptides and methods for use |
| US8501167B2 (en) | 2007-03-19 | 2013-08-06 | Globeimmune, Inc. | Compositions and methods for targeted ablation of mutational escape of targeted therapies for cancer |
| WO2009042645A2 (en) * | 2007-09-24 | 2009-04-02 | President And Fellows Of Harvard College | The use of mice predisposed to develop ulcerative colitis and colon cancer to develop metabolic profiles associated with same |
| WO2010033841A1 (en) | 2008-09-19 | 2010-03-25 | Globeimmune, Inc. | Immunotherapy for chronic hepatitis c virus infection |
| WO2010065626A1 (en) | 2008-12-02 | 2010-06-10 | Globeimmune, Inc. | Genotyping tools, methods and kits |
| MX2011010977A (es) | 2009-04-17 | 2012-02-29 | Us Health | Composiciones inmunoterapeuticas combinadas contra cancer y metodos. |
| CA2774326C (en) | 2009-09-14 | 2023-11-07 | Donald Bellgrau | Modulation of yeast-based immunotherapy products and responses |
| EP2547792A4 (en) | 2010-03-14 | 2013-11-27 | Globeimmune Inc | PHARMACOGENOMIC TREATMENT AND ADAPTATION TO THE RESPONSE OF AN INFECTIOUS DISEASE USING YEAST IMMUNOTHERAPY |
| GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
| WO2012019127A2 (en) | 2010-08-05 | 2012-02-09 | The Regents Of The University Of Colorado | Combination yeast-based immunotherapy and arginine therapy for the treatment of myeloid-derived supressor cell-associated diseases |
| US9254320B2 (en) | 2010-12-17 | 2016-02-09 | Globeimmune, Inc. | Compositions and methods for the treatment or prevention of human adenovirus-36 infection |
| JP5745102B2 (ja) | 2011-02-12 | 2015-07-08 | グローブイミューン，インコーポレイテッド | 慢性ｂ型肝炎感染症のための酵母系免疫療法組成物 |
| MX350661B (es) * | 2011-03-17 | 2017-09-13 | Us Health | Composiciones inmunoterapeuticas de levadura-brachyuri. |
| CN103732250A (zh) | 2011-06-14 | 2014-04-16 | 全球免疫股份有限公司 | 基于酵母的治疗或预防丁型肝炎病毒感染的组合物和方法 |
| SG10201607663YA (en) | 2011-08-17 | 2016-11-29 | Globeimmune Inc | Yeast-muc1 immunotherapeutic compositions and uses thereof |
| AU2014265873B2 (en) * | 2013-03-19 | 2019-01-17 | Globeimmune, Inc. | Yeast-based immunotherapy for chordoma |
-
2016
- 2016-08-01 AU AU2016303525A patent/AU2016303525B2/en active Active
- 2016-08-01 TW TW105124349A patent/TWI748957B/zh active
- 2016-08-01 HK HK18109071.3A patent/HK1249431A1/zh unknown
- 2016-08-01 CA CA2994272A patent/CA2994272C/en active Active
- 2016-08-01 JP JP2018505476A patent/JP6789283B2/ja active Active
- 2016-08-01 KR KR1020187006157A patent/KR102833272B1/ko active Active
- 2016-08-01 US US15/749,832 patent/US11065313B2/en active Active
- 2016-08-01 EP EP16750335.8A patent/EP3331552B1/en active Active
- 2016-08-01 WO PCT/US2016/044977 patent/WO2017023840A1/en not_active Ceased
- 2016-08-01 CN CN201680056316.XA patent/CN108348586B/zh active Active
-
2018
- 2018-01-29 IL IL257208A patent/IL257208B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2018522041A5 (2) | ||
| Zuo et al. | An engineered oncolytic vaccinia virus encoding a single-chain variable fragment against TIGIT induces effective antitumor immunity and synergizes with PD-1 or LAG-3 blockade | |
| TWI704226B (zh) | 重組溶瘤病毒組合物及其用途 | |
| JP7564572B2 (ja) | 単離された組換え体腫瘍溶解性ワクシニアウイルスとｎｋ細胞を含む治療薬、その使用およびそれを適用したキット | |
| JP2018535668A5 (2) | ||
| Francis et al. | Modulation of chemokines in the tumor microenvironment enhances oncolytic virotherapy for colorectal cancer | |
| JP2014509595A5 (2) | ||
| RU2015103758A (ru) | Днк-вакцина для применения у пациентов с раком поджелудочной железы | |
| JP2021518414A5 (2) | ||
| RU2019132253A (ru) | Новая днк-вакцина, нацеленная на pd-l1, для иммунотерапии рака | |
| JP2014139185A5 (2) | ||
| JP2020511139A5 (2) | ||
| CN105031630A (zh) | 同时分泌pd-1中和抗体和gm-csf因子的肿瘤细胞疫苗及其制备方法 | |
| Molinelli et al. | Biologic therapy in psoriasis (Part II): efficacy and safety of new treatment targeting IL23/IL-17 pathways | |
| CN105462975A (zh) | 一种特异性抑制ctgf基因表达的小干扰rna及其应用 | |
| JP2015000064A5 (2) | ||
| Xue et al. | Anti-tumour research of recombinant BCG using BZLF1 and hGM-CSF fusion genes | |
| JP2014534262A5 (2) | ||
| CN113425856B (zh) | 一种含有基因修饰的溶瘤病毒的药物组合物及其在治疗癌症的用途 | |
| CN105462976A (zh) | 一种特异性抑制twist1基因表达的小干扰rna及其应用 | |
| Bakacs | Turning self cancer cells into nonself by viral xenogenization | |
| KR20220079799A (ko) | 예방접종 및 질환 요법을 위한 자가유래 유도 만능 줄기 세포와의 폭스바이러스의 용도 | |
| Iyer et al. | Molecular insights and promise of oncolytic virus based immunotherapy | |
| CN102559753A (zh) | Il-24和osm双基因共表达重组质粒和重组腺病毒以及应用 | |
| Alshareef et al. | MEDU-23. IMPROVING IMMUNOTHERAPEUTIC POTENTIAL IN GROUP 3 MEDULLOBLASTOMA USING LOW DOSE RADIATION FOLLOWED BY 4-1BB MONOCLONAL ANTIBODY ADMINISTRATION |