JP2019043957A5 - - Google Patents
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- Publication number
- JP2019043957A5 JP2019043957A5 JP2018210606A JP2018210606A JP2019043957A5 JP 2019043957 A5 JP2019043957 A5 JP 2019043957A5 JP 2018210606 A JP2018210606 A JP 2018210606A JP 2018210606 A JP2018210606 A JP 2018210606A JP 2019043957 A5 JP2019043957 A5 JP 2019043957A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- group
- compound
- independently
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 0 CC(C)(CC1)[C@](*)C1(C)SC1(CC2)CC2(CC(*)O)CC1 Chemical compound CC(C)(CC1)[C@](*)C1(C)SC1(CC2)CC2(CC(*)O)CC1 0.000 description 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1315335.8 | 2013-08-29 | ||
| GBGB1315335.8A GB201315335D0 (en) | 2013-08-29 | 2013-08-29 | Amino diacids containing peptide modifiers |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537416A Division JP2016532705A (ja) | 2013-08-29 | 2014-08-28 | アミノ二酸含有ペプチド修飾剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019043957A JP2019043957A (ja) | 2019-03-22 |
| JP2019043957A5 true JP2019043957A5 (2) | 2019-05-09 |
| JP6767459B2 JP6767459B2 (ja) | 2020-10-14 |
Family
ID=49356024
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537416A Pending JP2016532705A (ja) | 2013-08-29 | 2014-08-28 | アミノ二酸含有ペプチド修飾剤 |
| JP2018210606A Active JP6767459B2 (ja) | 2013-08-29 | 2018-11-08 | アミノ二酸含有ペプチド修飾剤 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537416A Pending JP2016532705A (ja) | 2013-08-29 | 2014-08-28 | アミノ二酸含有ペプチド修飾剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US20160207957A1 (2) |
| EP (2) | EP3725801A3 (2) |
| JP (2) | JP2016532705A (2) |
| KR (1) | KR102461744B1 (2) |
| CN (2) | CN105683156A (2) |
| AU (2) | AU2014313779B2 (2) |
| CA (1) | CA2922220C (2) |
| ES (1) | ES2831974T3 (2) |
| GB (1) | GB201315335D0 (2) |
| WO (1) | WO2015028966A2 (2) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201315335D0 (en) * | 2013-08-29 | 2013-10-09 | Of Singapore | Amino diacids containing peptide modifiers |
| EP3433267B1 (en) * | 2016-03-23 | 2022-08-24 | Bachem Holding AG | Method for preparing glucagon-like peptides |
| US11338018B2 (en) | 2016-12-19 | 2022-05-24 | Harrow Ip, Llc | Adrenocorticotropic hormone-based pharmaceutical formulations and methods for fabricating and using thereof |
| CN110294800B (zh) * | 2018-03-22 | 2022-03-04 | 齐鲁制药有限公司 | 一种索玛鲁肽的制备方法 |
| JP7377257B2 (ja) * | 2018-08-09 | 2023-11-09 | エフ． ホフマン－ラ ロシュ アーゲー | ペプチド合成のための開裂可能なリンカー |
| ES2938734T3 (es) | 2018-10-09 | 2023-04-14 | Fresenius Kabi Ipsum S R L | Procedimiento para la fabricación de análogos de GLP-1 |
| GB201816639D0 (en) * | 2018-10-12 | 2018-11-28 | Heptares Therapeutics Ltd | GLP-1 Receptor Antagonist |
| EP3911350A4 (en) * | 2019-01-17 | 2022-12-14 | Harrow IP, LLC | ADRENOCORTICOTROPIC HORMONE BASED PHARMACEUTICAL FORMULATIONS AND PROCESSES FOR THE PREPARATION AND USE THEREOF |
| CN109776323B (zh) * | 2019-01-28 | 2022-05-17 | 富乐马鸿凯（大连）医药有限公司 | 一种高效选择性制备脂肪二酸单叔丁酯的方法 |
| WO2020208409A1 (en) * | 2019-04-10 | 2020-10-15 | Dr. Reddy’S Laboratories Limited | Improved processes for the preparation of peptide intermediates/modifiers |
| CN110372785B (zh) * | 2019-07-25 | 2020-10-23 | 成都诺和晟泰生物科技有限公司 | 一种索马鲁肽的合成方法 |
| CN111269137A (zh) * | 2020-01-16 | 2020-06-12 | 浙江工业大学 | 一种液相法制备索马鲁肽侧链的方法 |
| CN111253287A (zh) * | 2020-01-16 | 2020-06-09 | 浙江工业大学 | 液相汇聚式合成索马鲁肽侧链的方法 |
| CN111285780A (zh) * | 2020-01-16 | 2020-06-16 | 浙江工业大学 | 索马鲁肽侧链的汇聚式液相合成法 |
| EP4110800A1 (en) | 2020-03-06 | 2023-01-04 | Sanofi | Peptides as selective gip receptor agonists |
| US20250243255A1 (en) | 2020-08-19 | 2025-07-31 | Sanofi | Crf2 receptor agonists and their use in therapy |
| KR20240055069A (ko) | 2021-09-06 | 2024-04-26 | 사노피 | 효력있는 선택적 gip 수용체 작용제로서의 신규 펩티드 |
| CN115504893B (zh) * | 2022-11-18 | 2023-03-10 | 成都普康生物科技有限公司 | 一种L-谷氨酸-α-叔丁酯的合成方法 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL128332A0 (en) | 1996-08-30 | 2000-01-31 | Novo Nordisk As | GLP-1 derivatives |
| WO1999048513A1 (en) | 1998-03-23 | 1999-09-30 | Trimeris, Inc. | Methods and compositions for peptide synthesis |
| US6716963B1 (en) * | 1998-05-22 | 2004-04-06 | Abbott Laboratories | Peptide antiangiogenic drugs |
| GB9812675D0 (en) | 1998-06-11 | 1998-08-12 | Univ Edinburgh | Peptides |
| DE19924606A1 (de) | 1999-05-28 | 2000-11-30 | Graffinity Pharm Design Gmbh | Ligand-Anker-Konjugate |
| EP1076066A1 (en) | 1999-07-12 | 2001-02-14 | Zealand Pharmaceuticals A/S | Peptides for lowering blood glucose levels |
| AU1607501A (en) * | 1999-11-15 | 2001-05-30 | Drug Innovation & Design, Inc. | Selective cellular targeting: multifunctional delivery vehicles |
| US6621548B2 (en) | 2001-06-15 | 2003-09-16 | Viztec, Inc. | Electrooptical displays constructed with polymer-coated elements positioned between substrates |
| US7671054B1 (en) * | 2001-10-12 | 2010-03-02 | Choongwae Pharma Corporation | Reverse-turn mimetics and method relating thereto |
| KR20040058324A (ko) | 2001-11-26 | 2004-07-03 | 다이이찌 산토리 파마 가부시키가이샤 | 경비흡수용 의약 조성물 |
| JP2006501150A (ja) | 2002-05-03 | 2006-01-12 | アベシア・リミテッド | ペプチド合成のためのプロセス |
| KR101076018B1 (ko) | 2003-01-08 | 2011-10-21 | 유니버시티 오브 워싱톤 | 항균제 |
| US20040142379A1 (en) * | 2003-01-16 | 2004-07-22 | Carlsberg Research Laboratory | Affinity fishing for ligands and proteins receptors |
| CA2531988C (en) | 2003-08-05 | 2016-06-28 | Novo Nordisk A/S | Novel insulin derivatives |
| EP1692168B1 (en) | 2003-12-03 | 2011-07-20 | Novo Nordisk A/S | Single-chain insulin |
| WO2005072061A2 (en) * | 2004-02-02 | 2005-08-11 | Biosight Ltd. | Conjugates for cancer therapy and diagnosis |
| WO2005082404A2 (en) * | 2004-02-27 | 2005-09-09 | Novo Nordisk A/S | Glp-2 derivatives modified by lipophilic substituents |
| WO2006037810A2 (en) | 2004-10-07 | 2006-04-13 | Novo Nordisk A/S | Protracted glp-1 compounds |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| CA2650035C (en) * | 2006-04-27 | 2015-02-03 | Intezyne Technologies, Inc. | Poly (ethylene glycol) containing chemically disparate endgroups |
| EP2074134A1 (en) | 2006-10-05 | 2009-07-01 | Lonza Ag | Method for peptide synthesis |
| KR101046846B1 (ko) | 2006-10-12 | 2011-07-06 | 동국제약 주식회사 | 고체상 합성법을 이용한 펩타이드의 제조방법 |
| JP5721432B2 (ja) | 2007-08-15 | 2015-05-20 | ノボ・ノルデイスク・エー／エス | アミノ酸含有アルキレングリコール反復単位を含むアシル部を有するインスリン |
| FR2921831B1 (fr) * | 2007-10-05 | 2014-05-09 | Oreal | Composition cosmetique ou dermatologique comprenant un polymere portant des groupes de jonction, et procede de traitement cosmetique |
| CN102026671B (zh) * | 2008-03-14 | 2014-09-03 | Visen医药公司 | 整联蛋白靶向试剂及使用其的体内和体外成像方法 |
| HUE032284T2 (en) * | 2008-03-18 | 2017-09-28 | Novo Nordisk As | Protease-stabilized, acylated insulin analogues |
| ES2561208T3 (es) | 2008-09-12 | 2016-02-25 | Novo Nordisk A/S | Método de acilación de un péptido o una proteína |
| CN102202681A (zh) * | 2008-11-05 | 2011-09-28 | 霍夫曼-拉罗奇有限公司 | 神经肽-2受体(y-2r)激动剂及其用途 |
| CN102282167B (zh) * | 2008-12-15 | 2014-08-13 | 西兰制药公司 | 胰高血糖素类似物 |
| BRPI1015108A2 (pt) | 2009-04-02 | 2016-04-26 | Shire Llc | pró-fármacos de aminoácidos e peptídios ligados a ácido dicarboxílico de opiáceos e seus usos |
| AU2010272944B2 (en) | 2009-07-13 | 2015-11-19 | Zealand Pharma A/S | Acylated glucagon analogues |
| JP2013507414A (ja) | 2009-10-13 | 2013-03-04 | エフ．ホフマン−ラ ロシュ アーゲー | 神経ペプチド−２受容体（ｙ−２ｒ）アゴニスト |
| US8703701B2 (en) | 2009-12-18 | 2014-04-22 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
| RS59459B1 (sr) | 2010-01-22 | 2019-11-29 | Novo Nordisk Healthcare Ag | Hormoni rasta sa produženom in-vivo efikasnošću |
| EP2552951A1 (en) | 2010-03-26 | 2013-02-06 | Novo Nordisk A/S | Novel glucagon analogues |
| US9169310B2 (en) | 2010-06-24 | 2015-10-27 | Zealand Pharma A/S | Glucagon analogues |
| WO2012006391A2 (en) * | 2010-07-07 | 2012-01-12 | Cornell University | Modulators for sirt5 and assays for screening same |
| JP2013209295A (ja) * | 2010-10-13 | 2013-10-10 | Takeda Chem Ind Ltd | ペプチド誘導体 |
| AU2011343664B2 (en) * | 2010-12-17 | 2015-10-08 | Arrowhead Pharmaceuticals, Inc. | Galactose cluster-pharmacokinetic modulator targeting moiety for siRNA |
| WO2012088268A2 (en) * | 2010-12-22 | 2012-06-28 | Cornell University | Modulators for sirt6 and assays for screening same |
| CN102286092B (zh) | 2011-09-14 | 2014-01-01 | 深圳翰宇药业股份有限公司 | 利拉鲁肽的固相合成方法 |
| CN104011070A (zh) | 2011-12-15 | 2014-08-27 | 爱德迪安（北京）生物技术有限公司 | 具有降血糖作用的化合物、组合物及其用途 |
| IN2014CN04401A (2) * | 2011-12-23 | 2015-09-04 | Zealand Pharma As | |
| CN102584944B (zh) | 2012-02-06 | 2014-12-17 | 成都圣诺生物科技股份有限公司 | 一种依非巴特的制备方法 |
| EP2664374A1 (en) | 2012-05-15 | 2013-11-20 | F. Hoffmann-La Roche AG | Lysin-glutamic acid dipeptide derivatives |
| CN102875665B (zh) * | 2012-09-28 | 2014-11-26 | 深圳翰宇药业股份有限公司 | 一种合成利拉鲁肽的方法 |
| CN103214568B (zh) * | 2013-03-08 | 2014-09-24 | 深圳翰宇药业股份有限公司 | 一种固相制备促胰液素的方法 |
| CN103242200A (zh) * | 2013-04-10 | 2013-08-14 | 吉尔生化（上海）有限公司 | 一种Nα-芴甲氧羰基-Nε-乙酰基-赖氨酸的制备方法 |
| GB201315335D0 (en) * | 2013-08-29 | 2013-10-09 | Of Singapore | Amino diacids containing peptide modifiers |
-
2013
- 2013-08-29 GB GBGB1315335.8A patent/GB201315335D0/en not_active Ceased
-
2014
- 2014-08-28 AU AU2014313779A patent/AU2014313779B2/en active Active
- 2014-08-28 CN CN201480059789.6A patent/CN105683156A/zh active Pending
- 2014-08-28 CN CN201811562748.5A patent/CN110003055B/zh active Active
- 2014-08-28 JP JP2016537416A patent/JP2016532705A/ja active Pending
- 2014-08-28 ES ES14792591T patent/ES2831974T3/es active Active
- 2014-08-28 US US14/914,374 patent/US20160207957A1/en not_active Abandoned
- 2014-08-28 EP EP20167381.1A patent/EP3725801A3/en active Pending
- 2014-08-28 EP EP14792591.1A patent/EP3038658B1/en active Active
- 2014-08-28 KR KR1020167007531A patent/KR102461744B1/ko active Active
- 2014-08-28 CA CA2922220A patent/CA2922220C/en active Active
- 2014-08-28 WO PCT/IB2014/064123 patent/WO2015028966A2/en not_active Ceased
-
2018
- 2018-11-08 JP JP2018210606A patent/JP6767459B2/ja active Active
- 2018-11-19 US US16/195,145 patent/US11634455B2/en active Active
-
2020
- 2020-06-30 AU AU2020204382A patent/AU2020204382B2/en active Active
-
2023
- 2023-03-23 US US18/189,057 patent/US12441760B2/en active Active
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