JP3966903B2 - ハムスターの強力な同種プロモーター - Google Patents
ハムスターの強力な同種プロモーター Download PDFInfo
- Publication number
- JP3966903B2 JP3966903B2 JP51628897A JP51628897A JP3966903B2 JP 3966903 B2 JP3966903 B2 JP 3966903B2 JP 51628897 A JP51628897 A JP 51628897A JP 51628897 A JP51628897 A JP 51628897A JP 3966903 B2 JP3966903 B2 JP 3966903B2
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- nucleic acid
- acid molecule
- promoter activity
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19539493A DE19539493A1 (de) | 1995-10-24 | 1995-10-24 | Starker homologer Promotor aus Hamster |
| DE19539493.3 | 1995-10-24 | ||
| PCT/EP1996/004631 WO1997015664A1 (de) | 1995-10-24 | 1996-10-24 | Starker homologer promotor aus hamster |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006187719A Division JP2006320330A (ja) | 1995-10-24 | 2006-07-07 | ハムスターのユビキチン遺伝子 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH11513572A JPH11513572A (ja) | 1999-11-24 |
| JPH11513572A5 JPH11513572A5 (2) | 2004-08-12 |
| JP3966903B2 true JP3966903B2 (ja) | 2007-08-29 |
Family
ID=7775593
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51628897A Expired - Lifetime JP3966903B2 (ja) | 1995-10-24 | 1996-10-24 | ハムスターの強力な同種プロモーター |
| JP2006187719A Pending JP2006320330A (ja) | 1995-10-24 | 2006-07-07 | ハムスターのユビキチン遺伝子 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006187719A Pending JP2006320330A (ja) | 1995-10-24 | 2006-07-07 | ハムスターのユビキチン遺伝子 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6063598A (2) |
| EP (2) | EP1803815A3 (2) |
| JP (2) | JP3966903B2 (2) |
| AT (1) | ATE355370T1 (2) |
| CA (1) | CA2234071C (2) |
| DE (2) | DE19539493A1 (2) |
| DK (1) | DK0857211T3 (2) |
| ES (1) | ES2281905T3 (2) |
| MX (1) | MX9802764A (2) |
| PT (1) | PT857211E (2) |
| WO (1) | WO1997015664A1 (2) |
Families Citing this family (92)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0961830A1 (en) * | 1997-01-29 | 1999-12-08 | Neurosearch A/S | EXPRESSION VECTORS AND METHODS FOR $i(IN VIVO) EXPRESSION OF THERAPEUTIC POLYPEPTIDES |
| EP1624067A3 (en) * | 2000-09-18 | 2006-03-15 | Genzyme Corporation | Expression vectors containing hybrid ubiquitin promoters |
| AU2001290984A1 (en) * | 2000-09-18 | 2002-04-02 | Genzyme Corporation | Expression vectors containing hybrid ubiquitin promoters |
| ATE466941T1 (de) * | 2001-07-04 | 2010-05-15 | Chromagenics Bv | Dns-sequenzen mit anti-repressor-aktivität |
| US7384744B2 (en) | 2002-11-29 | 2008-06-10 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Expression vector, methods for the production of heterologous gene products and for the selection of recombinant cells producing high levels of such products |
| US7344886B2 (en) | 2002-11-29 | 2008-03-18 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product |
| DE10256083A1 (de) | 2002-11-29 | 2004-08-12 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Expressionsvektor, Verfahren zur Herstellung von heterologen Genprodukten und Selektionsverfahren für hochproduzierende rekombinante Zellen |
| DE10338531A1 (de) | 2003-08-19 | 2005-04-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Reklonierung von Produktionszellen |
| US8669109B2 (en) | 2003-08-19 | 2014-03-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Methods of producing proteins in Chinese hamster ovary (CHO) cells |
| US20050101017A1 (en) * | 2003-11-10 | 2005-05-12 | Wojtek Auerbach | Method of improving gene targeting using a ubiquitin promoter |
| GB0509965D0 (en) * | 2005-05-17 | 2005-06-22 | Ml Lab Plc | Improved expression elements |
| US9163257B2 (en) * | 2005-06-20 | 2015-10-20 | Cadila Healthcare Limited | Expression vector and methods of producing high levels of proteins |
| EP1806365A1 (en) | 2006-01-05 | 2007-07-11 | Boehringer Ingelheim International GmbH | Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them |
| US20080124760A1 (en) * | 2006-07-26 | 2008-05-29 | Barbara Enenkel | Regulatory Nucleic Acid Elements |
| US8609820B2 (en) | 2011-10-28 | 2013-12-17 | Neotope Biosciences Limited | Humanized antibodies that recognize alpha-synuclein |
| NZ629296A (en) | 2012-01-27 | 2016-06-24 | Prothena Biosciences Ltd | Humanized antibodies that recognize alpha-synuclein |
| UA118441C2 (uk) | 2012-10-08 | 2019-01-25 | Протена Біосаєнсиз Лімітед | Антитіло, що розпізнає альфа-синуклеїн |
| EP2938726B1 (en) | 2012-12-31 | 2017-09-27 | Boehringer Ingelheim International GmbH | Heterologous intron within a signal peptide |
| WO2014102101A1 (en) | 2012-12-31 | 2014-07-03 | Boehringer Ingelheim International Gmbh | Novel intron sequences |
| CA2902026C (en) | 2013-03-13 | 2023-08-29 | Prothena Biosciences Limited | Tau immunotherapy |
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| EP3089760B1 (en) | 2013-12-31 | 2020-01-15 | ProteoNic Biotechnology IP B.V. | Construct and sequence for enhanced gene expression |
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| TW201623331A (zh) | 2014-03-12 | 2016-07-01 | 普羅帝納生物科學公司 | 抗黑色素瘤細胞黏著分子（ｍｃａｍ）抗體類及使用彼等之相關方法 |
| US10059761B2 (en) | 2014-03-12 | 2018-08-28 | Prothena Biosciences Limited | Anti-Laminin4 antibodies specific for LG4-5 |
| JP6744856B2 (ja) | 2014-04-08 | 2020-08-19 | プロセナ・バイオサイエンシズ・リミテッド | α−シヌクレインを認識する抗体を含む血液脳関門シャトル |
| HRP20230405T8 (hr) | 2014-12-10 | 2023-09-29 | Opko Biologics Ltd. | Metode proizvodnje dugo djelujućih ctp-modificiranih polipeptida hormona rasta |
| TWI769570B (zh) | 2015-01-28 | 2022-07-01 | 愛爾蘭商普羅佘納生物科技有限公司 | 抗甲狀腺素運送蛋白抗體 |
| TWI786505B (zh) | 2015-01-28 | 2022-12-11 | 愛爾蘭商普羅佘納生物科技有限公司 | 抗甲狀腺素運送蛋白抗體 |
| TWI718121B (zh) | 2015-01-28 | 2021-02-11 | 愛爾蘭商普羅佘納生物科技有限公司 | 抗甲狀腺素運送蛋白抗體 |
| WO2016186879A1 (en) | 2015-05-18 | 2016-11-24 | Zymtronix, Llc | Magnetically immobilized microbiocidal enzymes |
| EP3323166B1 (en) | 2015-07-15 | 2024-03-13 | ZYMtronix, Inc. | Automated bionanocatalyst production |
| WO2017046774A2 (en) | 2015-09-16 | 2017-03-23 | Prothena Biosciences Limited | Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis |
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| WO2017208210A1 (en) | 2016-06-03 | 2017-12-07 | Prothena Biosciences Limited | Anti-mcam antibodies and associated methods of use |
| JP7017013B2 (ja) | 2016-07-02 | 2022-02-08 | プロセナ バイオサイエンシーズ リミテッド | 抗トランスサイレチン抗体 |
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| CN110177869A (zh) | 2017-01-13 | 2019-08-27 | 加利福尼亚大学董事会 | 免疫改造的多能细胞 |
| CN110881274B (zh) | 2017-05-02 | 2024-11-15 | 普罗塞纳生物科学有限公司 | 识别tau的抗体 |
| JP2021502955A (ja) | 2017-09-28 | 2021-02-04 | プロセナ・バイオサイエンシズ・リミテッド | シヌクレイン病の治療のための投与レジメン |
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| US12391923B2 (en) | 2019-06-26 | 2025-08-19 | The Regents Of The University Of California | SIRPα-silenced natural killer (NK) cells |
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-
1995
- 1995-10-24 DE DE19539493A patent/DE19539493A1/de not_active Ceased
-
1996
- 1996-10-24 ES ES96937224T patent/ES2281905T3/es not_active Expired - Lifetime
- 1996-10-24 US US09/051,969 patent/US6063598A/en not_active Expired - Lifetime
- 1996-10-24 EP EP06126019A patent/EP1803815A3/de not_active Withdrawn
- 1996-10-24 CA CA002234071A patent/CA2234071C/en not_active Expired - Lifetime
- 1996-10-24 AT AT96937224T patent/ATE355370T1/de active
- 1996-10-24 EP EP96937224A patent/EP0857211B1/de not_active Expired - Lifetime
- 1996-10-24 DK DK96937224T patent/DK0857211T3/da active
- 1996-10-24 JP JP51628897A patent/JP3966903B2/ja not_active Expired - Lifetime
- 1996-10-24 PT PT96937224T patent/PT857211E/pt unknown
- 1996-10-24 DE DE59611420T patent/DE59611420D1/de not_active Expired - Lifetime
- 1996-10-24 WO PCT/EP1996/004631 patent/WO1997015664A1/de not_active Ceased
-
1998
- 1998-04-07 MX MX9802764A patent/MX9802764A/es active IP Right Grant
-
2006
- 2006-07-07 JP JP2006187719A patent/JP2006320330A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997015664A1 (de) | 1997-05-01 |
| EP0857211A1 (de) | 1998-08-12 |
| EP0857211B1 (de) | 2007-02-28 |
| DE19539493A1 (de) | 1997-04-30 |
| PT857211E (pt) | 2007-03-30 |
| ATE355370T1 (de) | 2006-03-15 |
| JPH11513572A (ja) | 1999-11-24 |
| EP1803815A3 (de) | 2007-08-29 |
| DK0857211T3 (da) | 2007-03-26 |
| MX9802764A (es) | 1998-11-30 |
| EP1803815A2 (de) | 2007-07-04 |
| CA2234071C (en) | 2003-01-21 |
| JP2006320330A (ja) | 2006-11-30 |
| DE59611420D1 (de) | 2007-04-12 |
| CA2234071A1 (en) | 1997-05-01 |
| ES2281905T3 (es) | 2007-10-01 |
| US6063598A (en) | 2000-05-16 |
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