|
EP0961830A1
(en)
*
|
1997-01-29 |
1999-12-08 |
Neurosearch A/S |
EXPRESSION VECTORS AND METHODS FOR $i(IN VIVO) EXPRESSION OF THERAPEUTIC POLYPEPTIDES
|
|
ATE310096T1
(de)
*
|
2000-09-18 |
2005-12-15 |
Genzyme Corp |
Expressionsvektoren mit hybriden ubiquitin- promotoren
|
|
EP1624067A3
(en)
*
|
2000-09-18 |
2006-03-15 |
Genzyme Corporation |
Expression vectors containing hybrid ubiquitin promoters
|
|
DE60237048D1
(de)
*
|
2001-07-04 |
2010-08-26 |
Chromagenics Bv |
DNS-Sequenzen mit Anti-Repressor-Aktivität
|
|
DE10256083A1
(de)
|
2002-11-29 |
2004-08-12 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Expressionsvektor, Verfahren zur Herstellung von heterologen Genprodukten und Selektionsverfahren für hochproduzierende rekombinante Zellen
|
|
US7384744B2
(en)
|
2002-11-29 |
2008-06-10 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
Expression vector, methods for the production of heterologous gene products and for the selection of recombinant cells producing high levels of such products
|
|
US7344886B2
(en)
|
2002-11-29 |
2008-03-18 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
Neomycin-phosphotransferase-genes and methods for the selection of recombinant cells producing high levels of a desired gene product
|
|
US8669109B2
(en)
|
2003-08-19 |
2014-03-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Methods of producing proteins in Chinese hamster ovary (CHO) cells
|
|
DE10338531A1
(de)
|
2003-08-19 |
2005-04-07 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Reklonierung von Produktionszellen
|
|
US20050101017A1
(en)
*
|
2003-11-10 |
2005-05-12 |
Wojtek Auerbach |
Method of improving gene targeting using a ubiquitin promoter
|
|
GB0509965D0
(en)
*
|
2005-05-17 |
2005-06-22 |
Ml Lab Plc |
Improved expression elements
|
|
EA011619B1
(ru)
*
|
2005-06-20 |
2009-04-28 |
Кадила Хелзкэр Лимитед |
Экспрессионный вектор и способ продуцирования высоких уровней белков
|
|
EP1806365A1
(en)
|
2006-01-05 |
2007-07-11 |
Boehringer Ingelheim International GmbH |
Antibody molecules specific for fibroblast activation protein and immunoconjugates containing them
|
|
US20080124760A1
(en)
*
|
2006-07-26 |
2008-05-29 |
Barbara Enenkel |
Regulatory Nucleic Acid Elements
|
|
EP2771031B1
(en)
|
2011-10-28 |
2018-04-18 |
Prothena Biosciences Limited |
Humanized antibodies that recognize alpha-synuclein
|
|
EP2807188B1
(en)
|
2012-01-27 |
2019-09-11 |
Prothena Biosciences Limited |
Humanized antibodies that recognize alpha-synuclein
|
|
UA118441C2
(uk)
|
2012-10-08 |
2019-01-25 |
Протена Біосаєнсиз Лімітед |
Антитіло, що розпізнає альфа-синуклеїн
|
|
WO2014102101A1
(en)
|
2012-12-31 |
2014-07-03 |
Boehringer Ingelheim International Gmbh |
Novel intron sequences
|
|
WO2014102103A2
(en)
|
2012-12-31 |
2014-07-03 |
Boehringer Ingelheim International Gmbh |
Heterologous intron within a signal peptide
|
|
WO2014165271A2
(en)
|
2013-03-13 |
2014-10-09 |
Neotope Biosciences Limited |
Tau immunotherapy
|
|
WO2014182972A2
(en)
|
2013-05-10 |
2014-11-13 |
The Regents Of The University Of California |
Diagnostic and monitoring system for huntington's disease
|
|
US10513555B2
(en)
|
2013-07-04 |
2019-12-24 |
Prothena Biosciences Limited |
Antibody formulations and methods
|
|
US9850302B2
(en)
|
2013-07-12 |
2017-12-26 |
Prothena Biosciences Limited |
Antibodies that recognize IAPP
|
|
WO2015004633A1
(en)
|
2013-07-12 |
2015-01-15 |
Neotope Biosciences Limited |
Antibodies that recognize islet-amyloid polypeptide (iapp)
|
|
US11191832B2
(en)
|
2013-11-19 |
2021-12-07 |
Prothena Biosciences Limited |
Monitoring immunotherapy of Lewy body disease from constipation symptoms
|
|
EP3666287A1
(en)
|
2013-12-31 |
2020-06-17 |
ProteoNic Biotechnology IP B.V. |
Construct and sequence for enhanced gene expression
|
|
WO2015136472A1
(en)
|
2014-03-12 |
2015-09-17 |
Prothena Biosciences Limited |
Anti-laminin4 antibodies specific for lg4-5
|
|
EP3116906A1
(en)
|
2014-03-12 |
2017-01-18 |
Prothena Biosciences Limited |
Anti-laminin4 antibodies specific for lg1-3
|
|
TW201623331A
(zh)
|
2014-03-12 |
2016-07-01 |
普羅帝納生物科學公司 |
抗黑色素瘤細胞黏著分子(mcam)抗體類及使用彼等之相關方法
|
|
PT3116911T
(pt)
|
2014-03-12 |
2019-09-04 |
Prothena Biosciences Ltd |
Anticorpos anti-mcam e métodos de utilização associados
|
|
US10562973B2
(en)
|
2014-04-08 |
2020-02-18 |
Prothena Bioscience Limited |
Blood-brain barrier shuttles containing antibodies recognizing alpha-synuclein
|
|
KR102527180B1
(ko)
|
2014-12-10 |
2023-04-27 |
옵코 바이오로직스 리미티드 |
장기간 작용성 ctp-변형된 성장 호르몬 폴리펩타이드의 제조 방법
|
|
TWI769570B
(zh)
|
2015-01-28 |
2022-07-01 |
愛爾蘭商普羅佘納生物科技有限公司 |
抗甲狀腺素運送蛋白抗體
|
|
TWI786505B
(zh)
|
2015-01-28 |
2022-12-11 |
愛爾蘭商普羅佘納生物科技有限公司 |
抗甲狀腺素運送蛋白抗體
|
|
TWI718121B
(zh)
|
2015-01-28 |
2021-02-11 |
愛爾蘭商普羅佘納生物科技有限公司 |
抗甲狀腺素運送蛋白抗體
|
|
CN107896481B
(zh)
|
2015-05-18 |
2021-07-06 |
齐姆特罗尼克斯公司 |
磁力固定化的杀微生物酶
|
|
JP2018519838A
(ja)
|
2015-07-15 |
2018-07-26 |
ザイムトロニクス エルエルシーZymtronix, Llc |
自動バイオナノ触媒製造
|
|
WO2017046774A2
(en)
|
2015-09-16 |
2017-03-23 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis
|
|
WO2017046776A2
(en)
|
2015-09-16 |
2017-03-23 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of giant cell arteritis, polymyalgia rheumatica or takayasu's arteritis
|
|
WO2017149513A1
(en)
|
2016-03-03 |
2017-09-08 |
Prothena Biosciences Limited |
Anti-mcam antibodies and associated methods of use
|
|
WO2017153953A1
(en)
|
2016-03-09 |
2017-09-14 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of granulomatous lung diseases
|
|
WO2017153955A1
(en)
|
2016-03-09 |
2017-09-14 |
Prothena Biosciences Limited |
Use of anti-mcam antibodies for treatment or prophylaxis of granulomatous lung diseases
|
|
US10906964B2
(en)
|
2016-05-02 |
2021-02-02 |
Prothena Biosciences Limited |
Antibodies recognizing tau
|
|
MX2018013384A
(es)
|
2016-05-02 |
2019-02-28 |
Prothena Biosciences Ltd |
Anticuerpos que reconocen tau.
|
|
EP3452507B1
(en)
|
2016-05-02 |
2022-10-19 |
Prothena Biosciences Limited |
Tau immunotherapy
|
|
WO2017208210A1
(en)
|
2016-06-03 |
2017-12-07 |
Prothena Biosciences Limited |
Anti-mcam antibodies and associated methods of use
|
|
JP7017013B2
(ja)
|
2016-07-02 |
2022-02-08 |
プロセナ バイオサイエンシーズ リミテッド |
抗トランスサイレチン抗体
|
|
JP7016470B2
(ja)
|
2016-07-02 |
2022-02-07 |
プロセナ バイオサイエンシーズ リミテッド |
抗トランスサイレチン抗体
|
|
EP3478714A2
(en)
|
2016-07-02 |
2019-05-08 |
Prothena Biosciences Limited |
Anti-transthyretin antibodies
|
|
EP4303228B1
(en)
|
2016-07-11 |
2026-05-27 |
OPKO Biologics Ltd. |
Long-acting coagulation factor vii and methods of producing same
|
|
CN109788762B
(zh)
|
2016-08-13 |
2023-07-11 |
齐姆特罗尼克斯催化系统股份有限公司 |
磁性固定化的杀生物酶和杀生物化学品
|
|
KR20240095477A
(ko)
|
2017-01-13 |
2024-06-25 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
면역조작된 만능 세포
|
|
SG11201910066QA
(en)
|
2017-05-02 |
2019-11-28 |
Prothena Biosciences Ltd |
Antibodies recognizing tau
|
|
CA3076313A1
(en)
|
2017-09-28 |
2019-04-04 |
Prothena Biosciences Limited |
Dosing regimes for treatment of synucleinopathies
|
|
KR102581734B1
(ko)
|
2017-10-06 |
2023-09-22 |
네오토프 뉴로사이언스 리미티드 |
트랜스타이레틴의 검출 방법
|
|
MA51223A
(fr)
|
2017-11-29 |
2020-10-07 |
Prothena Biosciences Ltd |
Formulation lyophilisée d'un anticorps monoclonal contre la transthyrétine
|
|
CN112805091A
(zh)
|
2018-09-05 |
2021-05-14 |
齐姆特罗尼克斯催化系统股份有限公司 |
在磁性支架上固定化的酶和微粒体
|
|
SG11202104549TA
(en)
|
2018-11-08 |
2021-05-28 |
Prothena Biosciences Ltd |
Antibodies recognizing tau
|
|
UA128431C2
(uk)
|
2018-11-26 |
2024-07-10 |
Форті Севен, Інк. |
ГУМАНІЗОВАНЕ АНТИТІЛО ДО c-Kit
|
|
TWI859197B
(zh)
|
2019-03-03 |
2024-10-21 |
愛爾蘭商普羅帝納生物科學公司 |
識別tau之抗體
|
|
US20220213434A1
(en)
|
2019-05-10 |
2022-07-07 |
The Regents Of The University Of California |
Modified pluripotent cells
|
|
US11162079B2
(en)
|
2019-05-10 |
2021-11-02 |
The Regents Of The University Of California |
Blood type O Rh-hypo-immunogenic pluripotent cells
|
|
US12391923B2
(en)
|
2019-06-26 |
2025-08-19 |
The Regents Of The University Of California |
SIRPα-silenced natural killer (NK) cells
|
|
EP4007596A1
(en)
|
2019-08-01 |
2022-06-08 |
Sana Biotechnology, Inc. |
Dux4 expressing cells and uses thereof
|
|
JP7728747B2
(ja)
|
2019-08-23 |
2025-08-25 |
サナ バイオテクノロジー,インコーポレイテッド |
Cd24発現細胞およびそれらの用途
|
|
JP7853210B2
(ja)
|
2020-01-13 |
2026-04-28 |
サナ バイオテクノロジー,インコーポレイテッド |
血液型抗原の修飾
|
|
EP4585223A3
(en)
|
2020-01-15 |
2025-07-30 |
The Regents of the University of California |
Transplanted cell protection via inhibition of polymorphonuclear cells
|
|
EP4090747A1
(en)
|
2020-01-17 |
2022-11-23 |
Sana Biotechnology, Inc. |
Safety switches for regulation of gene expression
|
|
EP4125961A1
(en)
|
2020-03-25 |
2023-02-08 |
Sana Biotechnology, Inc. |
Hypoimmunogenic neural cells for the treatment of neurological disorders and conditions
|
|
AU2021297540A1
(en)
|
2020-06-24 |
2023-02-02 |
Prothena Biosciences Limited |
Antibodies recognizing sortilin
|
|
AU2021325941A1
(en)
|
2020-08-13 |
2023-03-09 |
Sana Biotechnology, Inc. |
Methods of treating sensitized patients with hypoimmunogenic cells, and associated methods and compositions
|
|
US11965022B2
(en)
|
2020-12-31 |
2024-04-23 |
Sana Biotechnology, Inc. |
Methods and compositions for modulating CAR-T activity
|
|
AU2022277931A1
(en)
|
2021-05-19 |
2023-11-30 |
Sana Biotechnology, Inc. |
Hypoimmunogenic rhd negative primary t cells
|
|
US20240226164A1
(en)
|
2021-05-27 |
2024-07-11 |
Sana Biotechnology, Inc. |
Hypoimmunogenic cells comprising engineered hla-e or hla-g
|
|
CA3225283A1
(en)
|
2021-07-14 |
2023-01-19 |
Sonja SCHREPFER |
Altered expression of y chromosome-linked antigens in hypoimmunogenic cells
|
|
CA3227108A1
(en)
|
2021-08-11 |
2023-02-16 |
Xiaomeng HU |
Genetically modified primary cells for allogeneic cell therapy
|
|
AU2022326565A1
(en)
|
2021-08-11 |
2024-02-08 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy
|
|
AU2022325955A1
(en)
|
2021-08-11 |
2024-02-08 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions
|
|
AU2022325231A1
(en)
|
2021-08-11 |
2024-02-08 |
Sana Biotechnology, Inc. |
Genetically modified cells for allogeneic cell therapy to reduce complement-mediated inflammatory reactions
|
|
WO2023158836A1
(en)
|
2022-02-17 |
2023-08-24 |
Sana Biotechnology, Inc. |
Engineered cd47 proteins and uses thereof
|
|
WO2023173123A1
(en)
|
2022-03-11 |
2023-09-14 |
Sana Biotechnology, Inc. |
Genetically modified cells and compositions and uses thereof
|
|
WO2023183313A1
(en)
|
2022-03-22 |
2023-09-28 |
Sana Biotechnology, Inc. |
Engineering cells with a transgene in b2m or ciita locus and associated compositions and methods
|
|
TW202440929A
(zh)
|
2022-12-14 |
2024-10-16 |
加拿大商普羅維登斯治療控股公司 |
用於感染性疾病的組合物和方法
|
|
WO2024151541A1
(en)
|
2023-01-09 |
2024-07-18 |
Sana Biotechnology, Inc. |
Type-1 diabetes autoimmune mouse
|
|
CN121843705A
(zh)
|
2023-05-03 |
2026-04-10 |
萨那生物科技公司 |
工程化胰岛细胞的给药和施用方法
|
|
WO2024243236A2
(en)
|
2023-05-22 |
2024-11-28 |
Sana Biotechnology, Inc. |
Methods of delivery of islet cells and related methods
|
|
WO2025043172A1
(en)
|
2023-08-23 |
2025-02-27 |
Sana Biotechnology, Inc. |
Modified cd47 proteins and their uses
|
|
EP4777522A2
(en)
|
2023-09-15 |
2026-07-22 |
Prothena Platform Technologies Limited |
Methods, compositions, and kits including cell-penetrating agents
|
|
WO2025059486A1
(en)
|
2023-09-15 |
2025-03-20 |
Prothena Biosciences Limited |
Anti-tdp-43 antibodies and uses thereof
|
|
CN122070299A
(zh)
|
2023-09-15 |
2026-05-19 |
普罗塞纳生物科学有限公司 |
细胞穿透剂及其用途
|
|
WO2025059487A2
(en)
|
2023-09-15 |
2025-03-20 |
Othair Prothena Limited |
Cell penetrating agents and uses thereof
|
|
WO2025166633A2
(en)
|
2024-02-07 |
2025-08-14 |
Westlake Genetech. Ltd. |
Split gene editing systems and uses thereof
|