JP6975641B2 - アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法 - Google Patents

アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法 Download PDF

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JP6975641B2
JP6975641B2 JP2017553347A JP2017553347A JP6975641B2 JP 6975641 B2 JP6975641 B2 JP 6975641B2 JP 2017553347 A JP2017553347 A JP 2017553347A JP 2017553347 A JP2017553347 A JP 2017553347A JP 6975641 B2 JP6975641 B2 JP 6975641B2
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angptl3
dsrna
pat
irna
expression
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JP2018512155A (ja
JP2018512155A5 (2
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ウィリアム・クアーベス
ケビン・フィッツジェラルド
ジェイムズ・バトラー
ステファニー・ウィリアムズ
グレゴリー・ヒンクル
マルティン・マイアー
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Alnylam Pharmaceuticals Inc
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JP2017553347A 2015-04-13 2016-04-13 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法 Active JP6975641B2 (ja)

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Application Number Priority Date Filing Date Title
JP2021147698A JP7817806B2 (ja) 2015-04-13 2021-09-10 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法
JP2023169168A JP2024009838A (ja) 2015-04-13 2023-09-29 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562146604P 2015-04-13 2015-04-13
US62/146,604 2015-04-13
US201562261361P 2015-12-01 2015-12-01
US62/261,361 2015-12-01
PCT/US2016/027271 WO2016168286A1 (en) 2015-04-13 2016-04-13 Angiopoietin-like 3 (angptl3) irna compositions and methods of use thereof

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JP2018512155A JP2018512155A (ja) 2018-05-17
JP2018512155A5 JP2018512155A5 (2) 2019-05-23
JP6975641B2 true JP6975641B2 (ja) 2021-12-01

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JP2021147698A Active JP7817806B2 (ja) 2015-04-13 2021-09-10 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法
JP2023169168A Pending JP2024009838A (ja) 2015-04-13 2023-09-29 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法

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JP2023169168A Pending JP2024009838A (ja) 2015-04-13 2023-09-29 アンギオポエチン様３（ＡＮＧＰＴＬ３）ｉＲＮＡ組成物およびそれらの使用方法

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US (4) US10570393B2 (2)
EP (1) EP3283631A1 (2)
JP (3) JP6975641B2 (2)
KR (2) KR102749152B1 (2)
CN (2) CN107743522B (2)
AU (2) AU2016247922B2 (2)
BR (1) BR112017021053A2 (2)
CA (1) CA2982450A1 (2)
EA (1) EA201792263A1 (2)
IL (3) IL254786B (2)
MX (2) MX392757B (2)
TW (3) TWI862799B (2)
WO (1) WO2016168286A1 (2)

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WO2019105437A1 (zh) 2017-12-01 2019-06-06 苏州瑞博生物技术有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
JP7365052B2 (ja) 2017-12-01 2023-10-19 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用
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WO2020099482A2 (en) * 2018-11-13 2020-05-22 Lipigon Pharmaceuticals Ab Angptl 3 oligonucleotides influencing the regulation of the fatty acid metabolism
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WO2020233680A1 (zh) 2019-05-22 2020-11-26 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
JP7610268B2 (ja) 2019-05-22 2025-01-08 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド 核酸、薬物組成物及び複合体ならびに調製方法と使用
AU2020280438B2 (en) 2019-05-22 2025-03-06 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
EP3978609A4 (en) 2019-05-24 2024-02-07 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
CN115175685B (zh) * 2019-12-09 2024-12-13 艾姆皮瑞克公司 用于治疗血管生成素样4(angptl4)相关疾病的寡核苷酸
KR20230011913A (ko) 2020-03-04 2023-01-25 버브 테라퓨틱스, 인크. 표적화된 rna 전달을 위한 조성물 및 방법
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JP2023546103A (ja) * 2020-10-16 2023-11-01 サノフイ Ａｎｇｐｔｌ３を阻害するための新規のｒｎａ組成物および方法
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