JP7189021B2 - 医療において使用するための、免疫チェックポイントモジュレータと、細胞透過性ペプチド、カーゴ、及びtlrペプチドアゴニストを含む複合体との組合せ - Google Patents

医療において使用するための、免疫チェックポイントモジュレータと、細胞透過性ペプチド、カーゴ、及びtlrペプチドアゴニストを含む複合体との組合せ Download PDF

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JP7189021B2
JP7189021B2 JP2018548167A JP2018548167A JP7189021B2 JP 7189021 B2 JP7189021 B2 JP 7189021B2 JP 2018548167 A JP2018548167 A JP 2018548167A JP 2018548167 A JP2018548167 A JP 2018548167A JP 7189021 B2 JP7189021 B2 JP 7189021B2
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peptide
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antigen
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acid sequence
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マディア・デロアジ
エロディ・ベルヌー
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アマル セラピューティクス エスエー
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JP2018548167A 2016-03-16 2017-03-14 医療において使用するための、免疫チェックポイントモジュレータと、細胞透過性ペプチド、カーゴ、及びtlrペプチドアゴニストを含む複合体との組合せ Active JP7189021B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/EP2016/000472 WO2016146261A1 (en) 2015-03-16 2016-03-16 Combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist for use in medicine
EPPCT/EP2016/000472 2016-03-16
EP2016070264 2016-08-26
EPPCT/EP2016/070264 2016-08-26
PCT/EP2017/056034 WO2017157964A1 (en) 2016-03-16 2017-03-14 Combination of an immune checkpoint modulator and a complex comprising a cell penetrating peptide, a cargo and a tlr peptide agonist for use in medicine

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JP2019508444A JP2019508444A (ja) 2019-03-28
JP2019508444A5 JP2019508444A5 (2) 2020-04-09
JP7189021B2 true JP7189021B2 (ja) 2022-12-13

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JP2018548167A Active JP7189021B2 (ja) 2016-03-16 2017-03-14 医療において使用するための、免疫チェックポイントモジュレータと、細胞透過性ペプチド、カーゴ、及びtlrペプチドアゴニストを含む複合体との組合せ

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US (2) US20190175748A1 (2)
EP (1) EP3429618B1 (2)
JP (1) JP7189021B2 (2)
AU (1) AU2017234192B2 (2)
CA (1) CA3010779A1 (2)
DK (1) DK3429618T5 (2)
ES (1) ES2977541T3 (2)
FI (1) FI3429618T3 (2)
HR (1) HRP20240510T1 (2)
HU (1) HUE066998T2 (2)
LT (1) LT3429618T (2)
PL (1) PL3429618T3 (2)
PT (1) PT3429618T (2)
RS (1) RS65430B1 (2)
RU (2) RU2769314C1 (2)
SI (1) SI3429618T1 (2)
WO (1) WO2017157964A1 (2)

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IL299072A (en) 2015-12-02 2023-02-01 Memorial Sloan Kettering Cancer Center Antibodies and methods for using them
DK3429618T5 (da) 2016-03-16 2024-09-16 Amal Therapeutics Sa Kombination af en immuncheckpoint-modulator og et kompleks som omfatter et cellepenetrerende peptid, en last og en tlr-peptidagonist til anvendelse i medicin
DK3515476T3 (da) 2016-09-21 2024-09-02 Amal Therapeutics Sa Fusion der omfatter et cellepenetrerende peptid, en multiepitop og en trl-peptidagnost til behandlingen af cancer
SG10201912663YA (en) 2016-10-11 2020-03-30 Agenus Inc Anti-lag-3 antibodies and methods of use thereof
MA46770A (fr) 2016-11-09 2019-09-18 Agenus Inc Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
WO2018187515A1 (en) 2017-04-04 2018-10-11 Avidea Technologies, Inc. Peptide-based vaccines, methods of manufacturing, and uses thereof for inducing an immune response
US11643463B2 (en) 2017-05-19 2023-05-09 Wuxi Biologics (Shanghai) Co., Ltd. Monoclonal antibodies to cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)
GB201810058D0 (en) * 2018-06-19 2018-08-08 Cytovation As Combination therapy using a peptide
BR112021012536A2 (pt) 2018-12-26 2021-09-14 City Of Hope Proteínas de ligação anti-ctla4 mascaradas ativáveis
WO2021042171A1 (en) * 2019-09-04 2021-03-11 Ena Therapeutics Pty Ltd Cancer immunotherapy
EP4162037A1 (en) * 2020-06-03 2023-04-12 MV Biotherapeutics SA Combination of an atp-hydrolyzing enzyme and an immune checkpoint modulator and uses thereof
US20220389065A1 (en) * 2020-06-04 2022-12-08 The Catholic University Of Korea Industry-Academic Cooperation Foundation Anticancer composition comprising tlr5 agonist derived from flagellin as active ingredient
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