JPH0141627B2 - - Google Patents

Info

Publication number: JPH0141627B2
Authority: JP; Japan
Prior art keywords: group; lower alkyl; alkyl group; dibenzo; formula
Prior art date: 1976-05-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP52060578A

Other languages

English (en)

Japanese (ja)

Other versions

JPS52144687A (en

Inventor

Buratsutona Hansu

Sutoruni Angero

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Novartis AG

Original Assignee

Ciba Geigy AG

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-05-26

Filing date

1977-05-26

Publication date

1989-09-06

1977-05-26 Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG

1977-12-02 Publication of JPS52144687A publication Critical patent/JPS52144687A/ja

1989-09-06 Publication of JPH0141627B2 publication Critical patent/JPH0141627B2/ja

Status Granted legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/32—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems containing carbocyclic rings other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/74—Naphthothiophenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Other In-Based Heterocyclic Compounds (AREA)

JP6057877A 1976-05-26 1977-05-26 Production of novel azatetracycline and preparation thereof Granted JPS52144687A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH665076A CH624105A5 (en)	1976-05-26	1976-05-26	Process for the preparation of novel azatetracyclic compounds

Publications (2)

Publication Number	Publication Date
JPS52144687A JPS52144687A (en)	1977-12-02
JPH0141627B2 true JPH0141627B2 (fr)	1989-09-06

Family

ID=4312888

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP6057877A Granted JPS52144687A (en)	1976-05-26	1977-05-26	Production of novel azatetracycline and preparation thereof

Country Status (30)

Country	Link
JP (1)	JPS52144687A (fr)
AR (2)	AR227608A1 (fr)
AT (1)	AT356114B (fr)
AU (1)	AU510471B2 (fr)
BE (1)	BE855009A (fr)
CA (1)	CA1104566A (fr)
CH (2)	CH624105A5 (fr)
CS (2)	CS225103B2 (fr)
CY (1)	CY1211A (fr)
DD (1)	DD131169A5 (fr)
DE (1)	DE2723105C2 (fr)
DK (1)	DK150301C (fr)
ES (1)	ES459070A1 (fr)
FI (1)	FI64582C (fr)
FR (1)	FR2352816A1 (fr)
GB (1)	GB1578266A (fr)
GR (1)	GR72092B (fr)
HK (1)	HK8784A (fr)
HU (1)	HU177417B (fr)
IE (1)	IE45204B1 (fr)
IL (1)	IL52168A (fr)
KE (1)	KE3339A (fr)
MY (1)	MY8500099A (fr)
NL (1)	NL7705707A (fr)
NO (1)	NO148489C (fr)
NZ (1)	NZ184191A (fr)
PT (1)	PT66588B (fr)
SE (1)	SE427354B (fr)
SG (1)	SG63683G (fr)
ZA (1)	ZA773161B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0030916B1 (fr) *	1979-12-10	1984-08-29	Ciba-Geigy Ag	Carbonitriles azatétracycliques

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL178593C (nl) *	1974-01-31	1986-04-16	Akzo Nv	Werkwijze ter bereiding van een farmaceutisch preparaat op basis van een tetracyclische verbinding en werkwijze voor de bereiding van de daarbij te gebruiken tetracyclische verbindingen.
CH592095A5 (fr) *	1974-02-22	1977-10-14	Ciba Geigy Ag

1976
- 1976-05-26 CH CH665076A patent/CH624105A5/de not_active IP Right Cessation
1977
- 1977-05-20 CY CY1211A patent/CY1211A/xx unknown
- 1977-05-20 GB GB21304/77A patent/GB1578266A/en not_active Expired
- 1977-05-21 DE DE2723105A patent/DE2723105C2/de not_active Expired
- 1977-05-23 FR FR7715703A patent/FR2352816A1/fr active Granted
- 1977-05-24 GR GR53547A patent/GR72092B/el unknown
- 1977-05-24 NL NL7705707A patent/NL7705707A/xx not_active Application Discontinuation
- 1977-05-24 NZ NZ184191A patent/NZ184191A/xx unknown
- 1977-05-24 DD DD7700199101A patent/DD131169A5/xx unknown
- 1977-05-24 PT PT66588A patent/PT66588B/pt unknown
- 1977-05-24 ES ES459070A patent/ES459070A1/es not_active Expired
- 1977-05-24 FI FI771651A patent/FI64582C/fi not_active IP Right Cessation
- 1977-05-24 CA CA278,990A patent/CA1104566A/fr not_active Expired
- 1977-05-25 ZA ZA00773161A patent/ZA773161B/xx unknown
- 1977-05-25 AT AT372577A patent/AT356114B/de not_active IP Right Cessation
- 1977-05-25 DK DK229977A patent/DK150301C/da not_active IP Right Cessation
- 1977-05-25 SE SE7706120A patent/SE427354B/xx not_active IP Right Cessation
- 1977-05-25 HU HU77CI1744A patent/HU177417B/hu not_active IP Right Cessation
- 1977-05-25 AU AU25473/77A patent/AU510471B2/en not_active Expired
- 1977-05-25 NO NO771830A patent/NO148489C/no unknown
- 1977-05-25 IL IL52168A patent/IL52168A/xx unknown
- 1977-05-25 BE BE177877A patent/BE855009A/fr not_active IP Right Cessation
- 1977-05-25 IE IE1074/77A patent/IE45204B1/en not_active IP Right Cessation
- 1977-05-26 AR AR267787A patent/AR227608A1/es active
- 1977-05-26 JP JP6057877A patent/JPS52144687A/ja active Granted
- 1977-05-26 CS CS773475A patent/CS225103B2/cs unknown
- 1977-05-26 CS CS782988A patent/CS225106B2/cs unknown
1978
- 1978-06-18 AR AR272606A patent/AR228124A1/es active
1980
- 1980-02-01 CH CH83380A patent/CH624106A5/de not_active IP Right Cessation
1983
- 1983-10-19 SG SG63683A patent/SG63683G/en unknown
- 1983-10-24 KE KE3339A patent/KE3339A/xx unknown
1984
- 1984-02-01 HK HK87/84A patent/HK8784A/xx unknown
1985
- 1985-12-30 MY MY99/85A patent/MY8500099A/xx unknown

Also Published As

Publication number	Publication date
KE3339A (en)	1983-11-25
BE855009A (fr)	1977-11-25
AR227608A1 (es)	1982-11-30
ZA773161B (en)	1978-04-26
PT66588B (en)	1978-10-23
FR2352816A1 (fr)	1977-12-23
CY1211A (en)	1984-04-06
SE7706120L (sv)	1977-11-27
CH624106A5 (en)	1981-07-15
AT356114B (de)	1980-04-10
NO148489B (no)	1983-07-11
IL52168A0 (en)	1977-07-31
FI771651A7 (fr)	1977-11-27
NZ184191A (en)	1979-12-11
IL52168A (en)	1981-07-31
CH624105A5 (en)	1981-07-15
CA1104566A (fr)	1981-07-07
DK229977A (da)	1977-11-27
FI64582C (fi)	1983-12-12
SG63683G (en)	1984-07-27
DK150301C (da)	1988-01-04
MY8500099A (en)	1985-12-31
ES459070A1 (es)	1978-04-16
JPS52144687A (en)	1977-12-02
SE427354B (sv)	1983-03-28
IE45204B1 (en)	1982-07-14
FR2352816B1 (fr)	1980-01-18
NL7705707A (nl)	1977-11-29
ATA372577A (de)	1979-09-15
GB1578266A (en)	1980-11-05
HK8784A (en)	1984-02-10
CS225106B2 (en)	1984-02-13
DE2723105A1 (de)	1977-12-15
NO771830L (no)	1977-11-29
DE2723105C2 (de)	1987-03-12
CS225103B2 (en)	1984-02-13
DD131169A5 (de)	1978-06-07
GR72092B (fr)	1983-09-13
IE45204L (en)	1977-11-26
FI64582B (fi)	1983-08-31
DK150301B (da)	1987-02-02
AR228124A1 (es)	1983-01-31
NO148489C (no)	1983-10-19
AU510471B2 (en)	1980-06-26
HU177417B (en)	1981-10-28
AU2547377A (en)	1978-11-30
PT66588A (en)	1977-06-01

Publication	Publication Date	Title
HU205744B (en)	1992-06-29	Process for producing substituted benzazepines and pharmaceutical compositions comprising same
US4399141A (en)	1983-08-16	5-Alkyl or hydroxyalkyl substituted-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imines and anticonvulsant use thereof
US4888335A (en)	1989-12-19	3-alkoxy-2-aminopropyl heterocyclic amines and their use as cardiovascular agents
GB1599907A (en)	1981-10-07	Isoindolines
CA1161857A (fr)	1984-02-07	Derives de 3-amino-1-benzoxepine; leurs sels et leurs compositions pharmaceutiques et methode de preparation
DE2723105C2 (de)	1987-03-12	Azatetracyclene, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Zusammensetzungen
US4171366A (en)	1979-10-16	1-Naphthothienylalkyl-1H-imidazoles
AU777221B2 (en)	2004-10-07	Heterocycle substituted diphenyl leukotriene antagonists
EP0011206B1 (fr)	1983-01-19	9,10-Dihydro-4H-benzo(4,5)cyclohepta(1,2-b)thiophèn-4,9-imines, procédé pour leur préparation et compositions pharmaceutiques les contenant
NZ238055A (en)	1993-08-26	4-amino-7-oxo-tetrahydrobenzothienopyridine-3-carboxylic acid derivatives, precursors and medicaments
IE51635B1 (en)	1987-01-21	5-substituted 9-cyanomethylene-dithieno(3,4-b:4',3-e)-azepines,their preparation,and therapeutic agents which contain these compounds
US4508716A (en)	1985-04-02	[1,2]-Fused 1,4-benzodiazepine compounds, process for their preparation and compositions containing them
HU179948B (en)	1983-01-28	Process for preparing new piperazino- and hexahydroazepino/1,2-a/-pyrrolo/2,1-c/1,4-benzodiazepine derivatives and pharmaceutical compositions containing such compounds
US4707476A (en)	1987-11-17	Treating states of agitation with azatetracyclic compounds
US4263315A (en)	1981-04-21	Azatetracyclic carbonitriles
AU622506B2 (en)	1992-04-09	Novel derivatives of 1,7-(imidazo-(1,2-a)pyridine)5'-6'h) ones
JPS5839682A (ja)	1983-03-08	ベンズアゼピン類
KR850000610B1 (ko)	1985-05-01	아자테트라사이클릭 카보니트릴의 제조방법
WO1984002704A1 (fr)	1984-07-19	Composes tetracycliques
WO1984002704A2 (fr)	1984-07-19	Composes tetracycliques
PL81742B1 (en)	1975-08-30	Process for the production of new thiepine derivatives[ca940531a]
TW449601B (en)	2001-08-11	Substituted tetracyclic oxazepine and thiazepine derivatives
JP2000502051A (ja)	2000-02-22	５ｈｔ▲下１ｄ▼レセプターアンタゴニストとしての三環系スピロ化合物
MXPA00009815A (en)	2002-06-05	Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression (5-ht1 receptor antagonists)
WO2004099196A1 (fr)	2004-11-18	Derives de benzoxazinone, preparation et utilisation associees