JPH01503784A - 皮脂を溶解する非水性ミノキシジル処方 - Google Patents

皮脂を溶解する非水性ミノキシジル処方

Info

Publication number: JPH01503784A
Authority: JP; Japan
Prior art keywords: minoxidil; solvent; composition; propylene; volume
Prior art date: 1986-09-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP62505492A

Other languages

English (en)

Japanese (ja)

Inventor

ハッツェンブーラー，ダグラス・エイ

ブラウン，ジェフリー・エドワード

ペナ，ローレイン・エリザベス

Original Assignee

ジ・アップジョン・カンパニー

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-05

Filing date

1987-09-02

Publication date

1989-12-21

1987-09-02 Application filed by ジ・アップジョン・カンパニー filed Critical ジ・アップジョン・カンパニー

1989-12-21 Publication of JPH01503784A publication Critical patent/JPH01503784A/ja

Status Pending legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title claims description 47
ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 title claims description 32
229960003632 minoxidil Drugs 0.000 title claims description 32
210000002374 sebum Anatomy 0.000 title claims description 18
238000009472 formulation Methods 0.000 title claims description 16
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 48
ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 claims description 18
229940055577 oleyl alcohol Drugs 0.000 claims description 18
XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 claims description 18
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 14
239000006184 cosolvent Substances 0.000 claims description 14
239000002904 solvent Substances 0.000 claims description 14
230000000699 topical effect Effects 0.000 claims description 11
QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 claims description 10
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 8
229920002545 silicone oil Polymers 0.000 claims description 8
239000012454 non-polar solvent Substances 0.000 claims description 6
-1 propylene cetyl ether Chemical compound 0.000 claims description 5
125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 claims description 5
210000004209 hair Anatomy 0.000 claims description 3
210000000434 stratum corneum Anatomy 0.000 claims description 3
239000004094 surface-active agent Substances 0.000 claims description 3
239000000839 emulsion Substances 0.000 claims description 2
229920001296 polysiloxane Polymers 0.000 claims description 2
206010040880 Skin irritation Diseases 0.000 claims 1
230000036556 skin irritation Effects 0.000 claims 1
231100000475 skin irritation Toxicity 0.000 claims 1
UMFCIIBZHQXRCJ-NSCUHMNNSA-N trans-anol Chemical compound C\C=C\C1=CC=C(O)C=C1 UMFCIIBZHQXRCJ-NSCUHMNNSA-N 0.000 claims 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 18
210000003491 skin Anatomy 0.000 description 11
210000003995 blood forming stem cell Anatomy 0.000 description 7
238000000034 method Methods 0.000 description 6
239000000243 solution Substances 0.000 description 6
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
150000001875 compounds Chemical class 0.000 description 5
239000012530 fluid Substances 0.000 description 5
210000003780 hair follicle Anatomy 0.000 description 5
230000035515 penetration Effects 0.000 description 4
BBEAQIROQSPTKN-UHFFFAOYSA-N pyrene Chemical compound C1=CC=C2C=CC3=CC=CC4=CC=C1C2=C43 BBEAQIROQSPTKN-UHFFFAOYSA-N 0.000 description 4
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 description 3
UAOMVDZJSHZZME-UHFFFAOYSA-N diisopropylamine Chemical compound CC(C)NC(C)C UAOMVDZJSHZZME-UHFFFAOYSA-N 0.000 description 3
230000003779 hair growth Effects 0.000 description 3
WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 3
239000003921 oil Substances 0.000 description 3
201000004384 Alopecia Diseases 0.000 description 2
LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 2
XSIFPSYPOVKYCO-UHFFFAOYSA-N butyl benzoate Chemical compound CCCCOC(=O)C1=CC=CC=C1 XSIFPSYPOVKYCO-UHFFFAOYSA-N 0.000 description 2
239000002537 cosmetic Substances 0.000 description 2
DOIRQSBPFJWKBE-UHFFFAOYSA-N dibutyl phthalate Chemical compound CCCCOC(=O)C1=CC=CC=C1C(=O)OCCCC DOIRQSBPFJWKBE-UHFFFAOYSA-N 0.000 description 2
LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 2
229940079593 drug Drugs 0.000 description 2
239000003814 drug Substances 0.000 description 2
230000002500 effect on skin Effects 0.000 description 2
SHZIWNPUGXLXDT-UHFFFAOYSA-N ethyl hexanoate Chemical compound CCCCCC(=O)OCC SHZIWNPUGXLXDT-UHFFFAOYSA-N 0.000 description 2
GVEPBJHOBDJJJI-UHFFFAOYSA-N fluoranthrene Natural products C1=CC(C2=CC=CC=C22)=C3C2=CC=CC3=C1 GVEPBJHOBDJJJI-UHFFFAOYSA-N 0.000 description 2
230000003676 hair loss Effects 0.000 description 2
ZSIAUFGUXNUGDI-UHFFFAOYSA-N hexan-1-ol Chemical compound CCCCCCO ZSIAUFGUXNUGDI-UHFFFAOYSA-N 0.000 description 2
238000000338 in vitro Methods 0.000 description 2
230000007794 irritation Effects 0.000 description 2
238000005259 measurement Methods 0.000 description 2
229940113115 polyethylene glycol 200 Drugs 0.000 description 2
229940068918 polyethylene glycol 400 Drugs 0.000 description 2
239000000126 substance Substances 0.000 description 2
238000012360 testing method Methods 0.000 description 2
WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 description 1
FDCJDKXCCYFOCV-UHFFFAOYSA-N 1-hexadecoxyhexadecane Chemical compound CCCCCCCCCCCCCCCCOCCCCCCCCCCCCCCCC FDCJDKXCCYFOCV-UHFFFAOYSA-N 0.000 description 1
KDWYBFCNTYIRFX-UHFFFAOYSA-N 2-[2-(2-amino-6-oxo-3h-purin-9-yl)ethoxy]ethylphosphonic acid Chemical compound O=C1NC(N)=NC2=C1N=CN2CCOCCP(O)(O)=O KDWYBFCNTYIRFX-UHFFFAOYSA-N 0.000 description 1
LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
241001340526 Chrysoclista linneella Species 0.000 description 1
XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 1
229920004511 Dow Corning® 200 Fluid Polymers 0.000 description 1
206010020772 Hypertension Diseases 0.000 description 1
OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
241000282553 Macaca Species 0.000 description 1
SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 1
239000005642 Oleic acid Substances 0.000 description 1
ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
208000006440 Open Bite Diseases 0.000 description 1
229920000604 Polyethylene Glycol 200 Polymers 0.000 description 1
229920002565 Polyethylene Glycol 400 Polymers 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
230000037374 absorbed through the skin Effects 0.000 description 1
239000002253 acid Substances 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
239000000443 aerosol Substances 0.000 description 1
150000001298 alcohols Chemical class 0.000 description 1
150000001412 amines Chemical class 0.000 description 1
210000000941 bile Anatomy 0.000 description 1
239000004202 carbamide Substances 0.000 description 1
150000001735 carboxylic acids Chemical class 0.000 description 1
239000003245 coal Substances 0.000 description 1
229940043279 diisopropylamine Drugs 0.000 description 1
238000009513 drug distribution Methods 0.000 description 1
239000003623 enhancer Substances 0.000 description 1
150000002148 esters Chemical class 0.000 description 1
230000004907 flux Effects 0.000 description 1
239000008240 homogeneous mixture Substances 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
235000015110 jellies Nutrition 0.000 description 1
OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
235000020778 linoleic acid Nutrition 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000006210 lotion Substances 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000000463 material Substances 0.000 description 1
231100000344 non-irritating Toxicity 0.000 description 1
239000002674 ointment Substances 0.000 description 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
239000006072 paste Substances 0.000 description 1
230000000149 penetrating effect Effects 0.000 description 1
239000003961 penetration enhancing agent Substances 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
229940127557 pharmaceutical product Drugs 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
YAAWASYJIRZXSZ-UHFFFAOYSA-N pyrimidine-2,4-diamine Chemical compound NC1=CC=NC(N)=N1 YAAWASYJIRZXSZ-UHFFFAOYSA-N 0.000 description 1
238000011160 research Methods 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
239000012047 saturated solution Substances 0.000 description 1
210000004761 scalp Anatomy 0.000 description 1
230000003381 solubilizing effect Effects 0.000 description 1
239000007921 spray Substances 0.000 description 1
229940100616 topical oil Drugs 0.000 description 1
238000012546 transfer Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Birds (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

JP62505492A 1986-09-05 1987-09-02 皮脂を溶解する非水性ミノキシジル処方 Pending JPH01503784A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US90414686A	1986-09-05	1986-09-05
US904,146		1986-09-05

Publications (1)

Publication Number	Publication Date
JPH01503784A true JPH01503784A (ja)	1989-12-21

Family

ID=25418653

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP62505492A Pending JPH01503784A (ja)	1986-09-05	1987-09-02	皮脂を溶解する非水性ミノキシジル処方

Country Status (9)

Country	Link
EP (1)	EP0315648B1 (da)
JP (1)	JPH01503784A (da)
KR (1)	KR880701539A (da)
AU (1)	AU597734B2 (da)
DE (1)	DE3778027D1 (da)
DK (1)	DK165164C (da)
FI (1)	FI91933B (da)
NO (1)	NO173685C (da)
WO (1)	WO1988001502A1 (da)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2001288031A (ja) *	2000-04-04	2001-10-16	Nippon Unicar Co Ltd	育毛剤用添加剤及び育毛剤組成物
JP2004505906A (ja) *	2000-08-09	2004-02-26	フアーマシア　アクチエボラグ	ミノキシジルの新規組成物
JP2018048105A (ja) *	2016-01-22	2018-03-29	大正製薬株式会社	外用組成物
JP2018048123A (ja) *	2016-09-15	2018-03-29	大正製薬株式会社	外用組成物
JP2018048104A (ja) *	2016-01-22	2018-03-29	大正製薬株式会社	外用組成物

Families Citing this family (29)

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Publication number	Priority date	Publication date	Assignee	Title
WO1994007478A1 (en) *	1992-10-06	1994-04-14	The Upjohn Company	Topical pharmaceutical compositions
EP1901064B1 (en)	1999-10-29	2016-01-13	Shiseido Company, Limited	Method for measuring skin absorbability
KR100416281B1 (ko) *	2000-05-23	2004-01-31	김영대	산화안정성이 있는 신규한 유화조성물
IL152486A0 (en)	2002-10-25	2003-05-29	Meir Eini	Alcohol-free cosmetic and pharmaceutical foam carrier
US8900554B2 (en)	2002-10-25	2014-12-02	Foamix Pharmaceuticals Ltd.	Foamable composition and uses thereof
US20080138296A1 (en)	2002-10-25	2008-06-12	Foamix Ltd.	Foam prepared from nanoemulsions and uses
US7704518B2 (en)	2003-08-04	2010-04-27	Foamix, Ltd.	Foamable vehicle and pharmaceutical compositions thereof
US8119150B2 (en) *	2002-10-25	2012-02-21	Foamix Ltd.	Non-flammable insecticide composition and uses thereof
US7700076B2 (en)	2002-10-25	2010-04-20	Foamix, Ltd.	Penetrating pharmaceutical foam
US9265725B2 (en)	2002-10-25	2016-02-23	Foamix Pharmaceuticals Ltd.	Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7820145B2 (en)	2003-08-04	2010-10-26	Foamix Ltd.	Oleaginous pharmaceutical and cosmetic foam
US9668972B2 (en)	2002-10-25	2017-06-06	Foamix Pharmaceuticals Ltd.	Nonsteroidal immunomodulating kit and composition and uses thereof
US9211259B2 (en)	2002-11-29	2015-12-15	Foamix Pharmaceuticals Ltd.	Antibiotic kit and composition and uses thereof
AU2003279493B2 (en)	2002-10-25	2009-08-20	Foamix Pharmaceuticals Ltd.	Cosmetic and pharmaceutical foam
US10117812B2 (en)	2002-10-25	2018-11-06	Foamix Pharmaceuticals Ltd.	Foamable composition combining a polar solvent and a hydrophobic carrier
US8795693B2 (en)	2003-08-04	2014-08-05	Foamix Ltd.	Compositions with modulating agents
US20080260655A1 (en)	2006-11-14	2008-10-23	Dov Tamarkin	Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en)	2007-08-07	2014-01-28	Foamix Ltd.	Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en)	2007-11-30	2016-09-13	Foamix Pharmaceuticals Ltd.	Foam containing benzoyl peroxide
WO2009090495A2 (en)	2007-12-07	2009-07-23	Foamix Ltd.	Oil and liquid silicone foamable carriers and formulations
WO2010125470A2 (en)	2009-04-28	2010-11-04	Foamix Ltd.	Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
WO2011013009A2 (en)	2009-07-29	2011-02-03	Foamix Ltd.	Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en)	2009-07-29	2011-02-03	Foamix Ltd.	Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
US9849142B2 (en)	2009-10-02	2017-12-26	Foamix Pharmaceuticals Ltd.	Methods for accelerated return of skin integrity and for the treatment of impetigo
MX359879B (es)	2009-10-02	2018-10-12	Foamix Pharmaceuticals Ltd	Composiciones tópicas de tetraciclina.
US9675537B2 (en)	2014-06-30	2017-06-13	Johnson & Johnson Consumer Inc.	Hair growth composition and method
CA2978573A1 (en)	2016-09-08	2018-03-08	Foamix Pharmaceuticals Ltd.	Compositions and methods for treating rosacea and acne
WO2019022679A1 (en) *	2017-07-26	2019-01-31	Thailand Center Of Excellence For Life Sciences (Public Organization)	METHODS AND FORMULATIONS FOR PROMOTING A HEAVY HAIR WITH TOPICAL APPLICATION OF HÉVÉA BRASILIENSIS EXTRACT
BR102021003531A2 (pt)	2021-02-24	2022-08-30	Eurofarma Laboratorios S.A.	Composição farmacêutica tópica espumável

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2643375A (en) *	1951-12-26	1953-06-23	Northwestern Res Corp	Method of treating hair
US4596812A (en) *	1976-05-24	1986-06-24	The Upjohn Company	Methods and solutions for treating male pattern alopecia
WO1985004577A1 (en) *	1984-04-06	1985-10-24	Gail Sansone Bazzano	Compositions used for hair growth
NZ214397A (en) *	1984-12-21	1989-04-26	Richardson Vicks Inc	Minoxidil and acrylate polymer topical compositions
AU8025787A (en) *	1986-09-12	1988-04-07	Upjohn Company, The	Foams for delivery of minoxidil

1987
- 1987-09-02 AU AU79617/87A patent/AU597734B2/en not_active Ceased
- 1987-09-02 DE DE8787905890T patent/DE3778027D1/de not_active Expired - Fee Related
- 1987-09-02 WO PCT/US1987/002168 patent/WO1988001502A1/en not_active Ceased
- 1987-09-02 EP EP87905890A patent/EP0315648B1/en not_active Expired - Lifetime
- 1987-09-02 JP JP62505492A patent/JPH01503784A/ja active Pending
1988
- 1988-03-28 KR KR1019880700336A patent/KR880701539A/ko not_active Withdrawn
- 1988-04-29 NO NO881893A patent/NO173685C/no unknown
- 1988-05-04 DK DK241588A patent/DK165164C/da not_active IP Right Cessation
1989
- 1989-03-03 FI FI891043A patent/FI91933B/fi not_active Application Discontinuation

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2001288031A (ja) *	2000-04-04	2001-10-16	Nippon Unicar Co Ltd	育毛剤用添加剤及び育毛剤組成物
JP2004505906A (ja) *	2000-08-09	2004-02-26	フアーマシア　アクチエボラグ	ミノキシジルの新規組成物
US7442369B1 (en)	2000-08-09	2008-10-28	Mcneil Ab	Compositions of minoxidil
JP2018048105A (ja) *	2016-01-22	2018-03-29	大正製薬株式会社	外用組成物
JP2018048104A (ja) *	2016-01-22	2018-03-29	大正製薬株式会社	外用組成物
JP2018162320A (ja) *	2016-01-22	2018-10-18	大正製薬株式会社	外用組成物
JP2018162319A (ja) *	2016-01-22	2018-10-18	大正製薬株式会社	外用組成物
JP2018048123A (ja) *	2016-09-15	2018-03-29	大正製薬株式会社	外用組成物
JP2021165305A (ja) *	2016-09-15	2021-10-14	大正製薬株式会社	外用組成物

Also Published As

Publication number	Publication date
FI91933B (fi)	1994-05-31
KR880701539A (ko)	1988-11-03
DK165164B (da)	1992-10-19
NO881893L (no)	1988-04-29
EP0315648A1 (en)	1989-05-17
DE3778027D1 (de)	1992-05-07
DK241588D0 (da)	1988-05-04
AU597734B2 (en)	1990-06-07
DK241588A (da)	1988-05-04
AU7961787A (en)	1988-03-24
WO1988001502A1 (en)	1988-03-10
FI891043A0 (fi)	1989-03-03
NO881893D0 (no)	1988-04-29
FI891043L (fi)	1989-03-03
NO173685B (no)	1993-10-11
DK165164C (da)	1993-03-01
EP0315648B1 (en)	1992-04-01
NO173685C (no)	1994-01-19

Publication	Publication Date	Title
JPH01503784A (ja)	1989-12-21	皮脂を溶解する非水性ミノキシジル処方
JP3081766B2 (ja)	2000-08-28	角質貯留型抗真菌外用組成物
US20090209548A1 (en)	2009-08-20	Formulation for stimulating hair growth
JP2003012511A (ja)	2003-01-15	エアゾール組成物
WO2001076541A1 (en)	2001-10-18	Hair growth stimulant compositions
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