JPH0226673B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to a detergent composition that satisfies essential requirements for a detergent, such as foaming properties and cleansing properties, while successfully reducing irritation to the skin significantly. Conventionally, as a surfactant for shampoos,
Whether it is products for professionals such as those used in hair salons or general commercial products, they mainly contain alkyl sulfate salts,
Polyoxyethylene alkyl sulfate salts, alkylbenzene sulfonates, α-olefin sulfonates, and the like have been widely used. However, although shampoos containing these surfactants have excellent cleaning power,
All of them are known to be highly irritating to the skin, although to varying degrees, and professionals who often come into contact with shampoo, such as barbers and beauticians, are more likely to experience skin problems such as rough hands. It is something. Also, these days, young people who have a particularly developed sense of cleanliness wash their hair more often, but even the general public washes their hair more often.
The number of hair washes has increased to 3 to 4 times a week or every day, and if you continue to wash your hair with shampoos that contain strong irritating surfactants, your scalp will become rough, leading to dandruff and itching. There are problems with connection etc. From these points of view, the current situation is that there is a strong demand for the use of shampoos that are hypoallergenic to the skin, not only for professional use but also for general commercial use. The present inventors focused on the above points and as a result of intensive research, we found that surfactants and surfactant compositions with strong protein denaturing power can cause severe roughness of hands and dandruff when used repeatedly. On the other hand, surfactants and shampoo compositions with low protein denaturing power are less likely to cause skin disorders such as rough hands even if used for a long period of time, and also significantly reduce the occurrence of dandruff on the scalp. I found it. That is, for various surfactants and mixed surfactant compositions, we measured the protein denaturation rate, conducted rough hand tests using actual human hands, and measured the amount of dandruff caused by actual use (prolonged use). They found that a surfactant or a mixed surfactant composition with a low oxidation rate tends to cause less rough hands and a tendency to reduce the amount of dandruff, leading to the completion of the invention of the present cleaning composition. That is, the present invention provides general formula (A) (In the formula, R ₁ is an alkyl group or alkenyl group having an average number of carbon atoms of 7 to 19, R ₂ is an average number of carbon atoms of 1
to 3 lower alkyl groups, M represents an alkali metal or an organic amine. ) an alkylyl alkyl taurine salt type anionic surfactant represented by general formula (B) (In the formula, R ₃ is an alkyl group or alkenyl group having an average of 8 to 20 carbon atoms, R ₄ and R ₅ are lower alkyl groups having an average of 1 to 3 carbon atoms, or -
Represents a CH ₂ CH ₂ OH group, -CH ₂ CH ₂ CH ₂ OH group. )
An amine oxide semipolar surfactant represented by the general formula (C) (In the formula, R ₆ represents an alkyl group or alkenyl group having an average number of carbon atoms of 7 to 19, m and n are integers, and m+n is 1 to 5.) The present invention provides a cleaning composition containing as an active ingredient. The preferred blending ratio of the active ingredients is that the weight ratio of (A):(B) is 9:1 to 1:2, and the weight ratio of (A)+(B):(C) is 15:1 to 1: 1, and (A) + (B)
+(C) accounts for 10 to 50% by weight of the total. Although the alkyloyl alkyl taurine salt type anionic surfactant represented by the general formula (A) has sufficient surfactant properties such as foaming properties and detergency,
It has a strong ability to denature proteins, and when used alone, the desired mild detergent cannot be obtained. On the other hand, the amine oxide type semipolar surfactant represented by the above general formula (B) has low protein denaturation ability and weak irritation, but has poor surfactant properties such as foaming and detergent properties. When used alone, there is a drawback that a cleaning agent with satisfactory performance cannot be obtained. The present inventors have determined that the alkyl taurate type anionic surfactant represented by the above general formula (A) and the amine oxide type semipolar surfactant represented by the above general formula (B) are mixed at a certain ratio. When mixed with
They discovered that phenomena such as an increase in viscosity and a decrease in critical micelle concentration occurred compared to when each agent was used alone, and assumed that a complex of anionic surfactant and amphoteric surfactant was formed. In the mixture of
The protein denaturation performance is superior to that of the alkyl alkyl taurine salt type anionic surfactant represented by (A) alone, and at the same time, the protein denaturation performance is superior to that of the amine oxide type semipolar surfactant represented by general formula (B) alone. It was discovered that there was a significant decrease, to a degree that was at least as good as that in the case of . In other words, by mixing to form a complex, a synergistic effect was clearly exerted, and it was possible to obtain a hypoallergenic surfactant composition with low protein denaturation ability while maintaining excellent surfactant ability. It is something. The weight ratio of (A):(B) is 9:
The ratio ranges from 1 to 1:2. If the mixing ratio is outside this range or if a large amount of other anionic surfactant is added to disrupt the balance of the system, a sufficient effect of lowering protein denaturation performance cannot be obtained. In addition, the alkylolamide type nonionic surfactant represented by the general formula (C) used in the present invention has traditionally been used in anionic surfactant shampoos to have a foaming enhancement effect, a thickening effect, and a low temperature effect. It is blended for the purpose of improving stability (reducing Kraft point), etc., but in the present invention, a certain amount of (C) is added to the mixture of (A) and (B) above. It has been found that the protein denaturation ability is further reduced by blending at a ratio of . Preferable (A)+(B):
The ratio of (C) is in the range of 15:1 to 1:1 by weight, and if the ratio of (A) + (B) is too large than this ratio, the protein denaturation reducing effect of (C) will not be fully exerted. First, if there is too much (C), the detergency and foaming properties of the shampoo will be impaired. Further, (A) + (B) + (C) is preferably 10 to 50% by weight of the total in order to form a liquid shampoo. In the present invention, the alkylyl alkyl taurine salt type anionic surfactant represented by the general formula (A) is, for example, as an alkylyl group R ₁ CO-:
C ₁₁ H ₂₃ CO―, C ₁₃ H ₂₇ CO―, C ₁₅ H ₃₁ CO―,
C ₁₇ H ₃₅ CO—, C ₁₇ H ₃₃ CO—, mixed alkylyl groups having 8 to 20 carbon atoms obtained from coconut oil fatty acids, etc., and the alkyl group R ₂ is CH ₃ —, C ₂ H ₅ —,
C ₃ H ₇ -, and the counter ion M is -Li, -
Examples include K, -Na, monoethanolamine, diethanolamine, and triethanolamine. In the amine oxide type semipolar surfactant represented by the general formula (B), for example, the alkyl group R ₃ is
C ₇ H ₁₅ ―, C ₉ H ₁₉ ―, C ₁₁ H ₂₃ ―, C ₁₃ H ₂₇ ―,
C ₁₅ H ₃₁ , C ₁₇ H ₃₃ —, C ₁₇ H ₃₁ —, C ₁₇ H ₂₉ —, mixed alkyl groups having 7 to 19 carbon atoms obtained from coconut oil, etc., and R ₄ and R ₅ are —CH ₃ , ―C ₂ H ₅ , ―
C ₃ H ₇ , ―CH ₂ OH, ―CH ₂ CH ₂ OH, ―
Examples include CH ₂ CH ₂ CH ₂ OH. The alkylolamide type nonionic surfactant represented by the general formula (C) has an alkylyl group, for example.
R ₆ CO— is C ₁₁ H ₂₃ CO—, C ₁₃ H ₂₇ CO—,
Examples include C ₁₅ H ₃₁ CO—, C ₁₇ H ₃₅ CO—, C ₁₇ H ₃₃ CO—, and mixed alkylyl groups having 8 to 20 carbon atoms obtained from coconut oil fatty acids. The cleaning composition of the present invention may optionally contain components commonly added to cleaning agents, such as higher alcohols, lanolin derivatives, protein derivatives, and oily components such as fatty acid esters of polyethylene glycol.
Humectant ingredients such as propylene glycol, glycerin, and polyethylene glycol, nonionic surfactants such as polyoxyethylene alkyl ether and polypropylene oxide block polymer, water-soluble polymer substances (anionic,
(including nonionic and cationic), sequestering agents, preservatives, bactericidal agents, PH regulators, ultraviolet absorbers, antioxidants, pigments, fragrances, and the like. Next, the present invention will be explained in detail using Examples, but the present invention is not limited thereto. Prior to the examples, the test methods and evaluation methods employed in each example will be explained. Foaming test method: 400 ml of a 1% sample concentration solution was prepared using CaCO ₃ 70 ppm artificial hard water, and the amount of foaming was measured using a cylindrical cylinder equipped with a stirrer at a temperature of 40°C. ○... Good foaming Foam volume 2000ml or more △… Normal foaming Foam volume 1500ml or more Less than 2000ml ×… Poor foaming Foam volume less than 1500ml Cleaning test method CaO/MgO = 3/1, 5゜DH artificial hard water, sample concentration 1% solution and washed artificial sebum-contaminated cloth using wool surge. Tergotometer (JIS K) at a temperature of 40℃
-3371), and the cleaning efficiency was determined from the reflectance before and after cleaning. Cleaning efficiency (%) = R _W − R _S / R _O − R _S × 100 R _O : Reflectance of original cloth (wool surge) R _S : Reflectance of contaminated cloth R _W : Reflectance of contaminated cloth after washing ○…Good cleaning efficiency Cleaning efficiency 80% or more△…Normal cleaning efficiency Cleaning efficiency 60% or more Less than 80%×…Poor cleaning performance Protein denaturation rate measurement method Using water-based high performance liquid chromatography, ovalbumin The ovalbumin denaturation rate when a sample was added to the PH7 buffer solution at a sample concentration of 1% was measured using the absorption peak at 220 nm. Denaturation rate (%) = H _O − H _S /H _O ×100 H _O : Height of the 220 nm absorption peak of ovalbumin H _S : Height of the 220 nm absorption peak when the sample is added to the ovalbumin buffer solution. ◎...Ovalbumin denaturation rate less than 30%〇...Ovalbumin denaturation rate 30% or more but less than 60%△...Ovalbumin denaturation rate 60% or more but less than 80%×...Ovalbumin denaturation rate 80% or more Rough hand test method For each sample, male and female Using a panel of 5 people each, 10 people in total, with one hand on either the left or right hand, sample concentration 5
%, and the other hand was immersed in water at the same temperature for 10 minutes twice a day for 2 consecutive days, and the difference in rough skin between the left and right hands was visually determined. ◎… Extremely weak hand roughness 0-1 out of 10 people
Roughness of hands was observed on the sample side〇…Roughness of hands was slightly weak 2 to 4 out of 10 people
Rough hands were observed on the sample side △…Slightly rough hands 5-7 out of 10 people
Rough hands were observed on the sample side ×…8 to 10 out of 10 people had extremely rough hands
Method for measuring the amount of dandruff produced when rough hands were observed on the sample side A panel that normally uses lauryl ether sulfate-based general commercial shampoo (one that does not contain drugs for dandruff itching) was asked to wash their hair at the same frequency as usual. Using the sample, the subjects washed their hair five times using the same hair washing method they usually use, and the amount of dandruff before and after using the sample was compared. The amount of dandruff on the third day after washing the hair with a commercially available shampoo and the amount of dandruff on the third day from the last day of washing the hair five times using the sample were measured. Dandruff is collected by suction from the head using a suction device with a cloth attached, and in order to eliminate errors caused by other foreign substances, the amount of nitrogen is determined using the Kjeldahl method, and this is multiplied by 6.25 to determine the average protein amount. (mg/head). The number of panels was three for each sample, and the average values were compared. ◎…After using the sample, the amount of dandruff is 30% or more
Decreased〇…After using the sample, the amount of dandruff is 10% or more
Less than 30% decrease △…After using the sample, the amount of dandruff is 0% or more
Less than 10% decrease×...Dandruff amount increased after sample use Examples 1 to 8 A shampoo consisting of the formulation shown in Table 1 below was prepared, and its foaming properties, detergency, and protein denaturation were evaluated. The rate, roughness of hands, and amount of dandruff were investigated. These results are shown in Table 1 (Example) and Table 2 (Comparative Example).

【table】

【table】

【table】

[Table] As described above, the examples of the present invention exhibited excellent performance in all of the foaming properties, cleansing properties, protein denaturation rate, roughness on hands, and amount of dandruff. Example 9 A shampoo having the following composition was prepared. Cocoyl methyl taurine-Na 10 (wt%) lauryl dimethylamine oxide 6 coconut fatty acid diethanolamide 4 glycerin 2 fragrance 0.3 water remainder Example 10 A shampoo having the following composition was prepared. Cocoyl methyl taurine-Na 10 (wt%) Lauryl dimethylamine oxide 6 Coconut fatty acid diethanolamide 4 Polyethylene glycol 2 Citric acid 0.2 Cationized cellulose ether 0.6 Fragrance 0.3 Water Residual Example 11 A shampoo with the following composition was prepared. . Ethylene glycol fatty acid ester
2 (wt%) Lauroyl methyl taurine-Na 10 Cocoyl dihydroxyethylamine oxide
6 Lauric acid diethanolamide 4 Poly(dimethyldiallylammonium chloride) 1 Citric acid 0.2 Fragrance 0.3 Water Residual

Claims (1)

[Claims] 1 General formula (A) (In the formula, R ₁ is an alkyl group or alkenyl group having an average of 7 to 19 carbon atoms, R ₂ is a lower alkyl group having an average of 1 to 3 carbon atoms, and M is an alkali metal or an organic amine.) An alkylyl alkyl taurine salt type anionic surfactant and general formula (B) (In the formula, R ₃ is an alkyl group or alkenyl group having an average of 8 to 20 carbon atoms, R ₄ and R ₅ are lower alkyl groups having an average of 1 to 3 carbon atoms,
Represents a CH ₂ CH ₂ OH group or a -CH ₂ CH ₂ CH ₂ OH group. ) and an amine oxide type semipolar surfactant represented by the general formula (C) (In the formula, R ₆ represents an alkyl group or alkenyl group having an average number of carbon atoms of 7 to 19, m and n are integers, and m+n is 1 to 5.) A cleaning composition containing as an active ingredient. 2 The weight ratio of the alkyl alkyl taurine salt type anionic surfactant represented by the general formula (A) and the amine oxide type semipolar surfactant represented by the general formula (B) is in the range of 9:1 to 1:2. and (A) + (B)
and the alkylolamide type nonionic surfactant represented by the general formula (C) in a weight ratio of 15:1 to 1:1.
The cleaning composition according to claim 1, wherein (A) + (B) + (C) is 10 to 50% by weight of the total.