JPH02500161A - 異種遺伝子の高水準誘導発現 - Google Patents

異種遺伝子の高水準誘導発現

Info

Publication number: JPH02500161A
Authority: JP; Japan
Prior art keywords: cells; receptor; ligand; cell line; gene
Prior art date: 1986-08-01
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP62504827A

Other languages

English (en)

Japanese (ja)

Inventor

カウフマン、ランダル・ジェイ

イスラエル、デーヴィッド

Original Assignee

ジェネテイックス・インスティテュート・インコーポレイテッド

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-08-01

Filing date

1987-07-31

Publication date

1990-01-25

1987-07-31 Application filed by ジェネテイックス・インスティテュート・インコーポレイテッド filed Critical ジェネテイックス・インスティテュート・インコーポレイテッド

1990-01-25 Publication of JPH02500161A publication Critical patent/JPH02500161A/ja

Status Pending legal-status Critical Current

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

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Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Hematology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

JP62504827A 1986-08-01 1987-07-31 異種遺伝子の高水準誘導発現 Pending JPH02500161A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US89311586A	1986-08-01	1986-08-01
US893,115		1986-08-01

Publications (1)

Publication Number	Publication Date
JPH02500161A true JPH02500161A (ja)	1990-01-25

Family

ID=25401056

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP62504827A Pending JPH02500161A (ja)	1986-08-01	1987-07-31	異種遺伝子の高水準誘導発現

Country Status (4)

Country	Link
EP (1)	EP0318500A4 (de)
JP (1)	JPH02500161A (de)
AU (1)	AU7802587A (de)
WO (1)	WO1988000975A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5071773A (en) *	1986-10-24	1991-12-10	The Salk Institute For Biological Studies	Hormone receptor-related bioassays
CA1309044C (en) *	1987-11-09	1992-10-20	Toshiya Takano	Method of producing foreign gene products
US5082774A (en) *	1988-08-30	1992-01-21	The General Hospital Corporation	Recombinant human nerve growth factor
US5091518A (en) *	1989-11-16	1992-02-25	The Salk Institute For Biological Studies	Beta retinoic acid response elements compositions and assays
US6492137B1 (en)	1989-11-16	2002-12-10	The Salk Institute For Biological Studies	Response element compositions and assays employing same
US5665873A (en) *	1995-02-09	1997-09-09	Dana Farber Cancer Institute	Glucocorticoid response elements
US20050164271A1 (en)	2004-01-20	2005-07-28	Sanjay Bhanot	Modulation of glucocorticoid receptor expression
JP2015501155A (ja)	2011-10-25	2015-01-15	アイシスファーマシューティカルズ，インコーポレーテッド	Ｇｃｃｒ発現のアンチセンス調整

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3280392D1 (de) *	1981-11-23	1992-03-26	University Patents Inc	Steuerung der dna-sequenzen-transkription.
CA1309044C (en) *	1987-11-09	1992-10-20	Toshiya Takano	Method of producing foreign gene products

1987
- 1987-07-31 EP EP19870905380 patent/EP0318500A4/de not_active Withdrawn
- 1987-07-31 AU AU78025/87A patent/AU7802587A/en not_active Abandoned
- 1987-07-31 JP JP62504827A patent/JPH02500161A/ja active Pending
- 1987-07-31 WO PCT/US1987/001871 patent/WO1988000975A1/en not_active Ceased

Also Published As

Publication number	Publication date
EP0318500A1 (de)	1989-06-07
AU7802587A (en)	1988-02-24
WO1988000975A1 (en)	1988-02-11
EP0318500A4 (de)	1989-12-22

Publication	Publication Date	Title
EP1694850B1 (de)	2011-06-29	Plasmidsystem zur expression mehrerer gene
US5122458A (en)	1992-06-16	Use of a bgh gdna polyadenylation signal in expression of non-bgh polypeptides in higher eukaryotic cells
JP4489424B2 (ja)	2010-06-23	染色体に基くプラットホーム
EP0873405B1 (de)	2004-09-08	Expressionssteigernde sequenzelemente (ease) für eukaryontische expressionssysteme
US5789247A (en)	1998-08-04	Expression in non-tumoral human lymphoblastoid lines with an integrative vector
MX2011002706A (es)	2011-07-20	Tornillo radiolucido con marcador radiopaco.
JPH04505104A (ja)	1992-09-10	相同組換え法を用いてのタンパク質の生成
EA016880B1 (ru)	2012-08-30	Элементы нуклеиновых кислот, обладающие регуляторной функцией
JP2002531103A (ja)	2002-09-24	組換え細胞の作成法
CA2104598C (en)	2003-01-07	Methods for selection of recombinant host cells expressing high levels of a desired protein
MX2011001644A (es)	2011-10-06	Un vector de expresion y un metodo del mismo.
JP2002262879A (ja)	2002-09-17	新規動物細胞用ベクターおよびその使用
IE914497A1 (en)	1992-07-01	Expression systems
JPH05503015A (ja)	1993-05-27	哺乳類発現ベクター
JPH02500161A (ja)	1990-01-25	異種遺伝子の高水準誘導発現
EP2692867B1 (de)	2016-11-30	Expressionsvektor für tierzellen
JPS62171696A (ja)	1987-07-28	ヒトエリスロポエチンの製造方法
EP2118119A2 (de)	2009-11-18	Verwendung des intron-1 des beta-aktin-gens von hühnern
AU600481B2 (en)	1990-08-16	Method of producing peptides, recombinant plasmid for use in the same and animal cells transformed with the same
Okamoto et al.	1990	Amplification and high-level expression of a cDNA for human granulocyte-macrophage colony-stimulating factor in human lymphoblastoid Namalwa cells
JP5073653B2 (ja)	2012-11-14	高レベルのタンパク質を産生する発現ベクター及び方法
EP0266057A2 (de)	1988-05-04	Eine eukaryotische sekretorische Signalsequenz enthaltendes Plasmid und Verfahren zur Sekretion der kodierten Proteine
JPH029368A (ja)	1990-01-12	発現ベクター
JPH02195888A (ja)	1990-08-02	ヒトインターロイキン２活性を有するポリペプチドをコードする遺伝子を含有する組換えｄｎａ体および該組換えｄｎａ体により形質転換された原核生物細胞
CN101341252A (zh)	2009-01-07	啮齿动物细胞中的蛋白质表达