JPH0254895B2 - - Google Patents

Info

Publication number
JPH0254895B2
JPH0254895B2 JP58221126A JP22112683A JPH0254895B2 JP H0254895 B2 JPH0254895 B2 JP H0254895B2 JP 58221126 A JP58221126 A JP 58221126A JP 22112683 A JP22112683 A JP 22112683A JP H0254895 B2 JPH0254895 B2 JP H0254895B2
Authority
JP
Japan
Prior art keywords
base material
mount
chemical analysis
groove
narrowing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58221126A
Other languages
English (en)
Other versions
JPS60113133A (ja
Inventor
Norio Sakamoto
Toshuki Ikarya
Kyohiko Takahashi
Masao Nakamura
Akira Yanagisawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Konica Minolta Inc
Original Assignee
Konica Minolta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Konica Minolta Inc filed Critical Konica Minolta Inc
Priority to JP58221126A priority Critical patent/JPS60113133A/ja
Priority to US06/672,098 priority patent/US4668472A/en
Priority to DE19843442820 priority patent/DE3442820A1/de
Publication of JPS60113133A publication Critical patent/JPS60113133A/ja
Publication of JPH0254895B2 publication Critical patent/JPH0254895B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
    • B65B61/04—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for severing webs, or for separating joined packages
    • B65B61/06—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for severing webs, or for separating joined packages by cutting
    • B65B61/08—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for severing webs, or for separating joined packages by cutting using rotary cutters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B9/00—Enclosing successive articles, or quantities of material, e.g. liquids or semiliquids, in flat, folded, or tubular webs of flexible sheet material; Subdividing filled flexible tubes to form packages
    • B65B9/02—Enclosing successive articles, or quantities of material between opposed webs
    • B65B9/04—Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material
    • B65B9/045—Enclosing successive articles, or quantities of material between opposed webs one or both webs being formed with pockets for the reception of the articles, or of the quantities of material for single articles, e.g. tablets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C65/00—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor
    • B29C65/02—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure
    • B29C65/08—Joining or sealing of preformed parts, e.g. welding of plastics materials; Apparatus therefor by heating, with or without pressure using ultrasonic vibrations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/11—Joint cross-sections comprising a single joint-segment, i.e. one of the parts to be joined comprising a single joint-segment in the joint cross-section
    • B29C66/112—Single lapped joints
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/01—General aspects dealing with the joint area or with the area to be joined
    • B29C66/05—Particular design of joint configurations
    • B29C66/10—Particular design of joint configurations particular design of the joint cross-sections
    • B29C66/13—Single flanged joints; Fin-type joints; Single hem joints; Edge joints; Interpenetrating fingered joints; Other specific particular designs of joint cross-sections not provided for in groups B29C66/11 - B29C66/12
    • B29C66/131—Single flanged joints, i.e. one of the parts to be joined being rigid and flanged in the joint area
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/50—General aspects of joining tubular articles; General aspects of joining long products, i.e. bars or profiled elements; General aspects of joining single elements to tubular articles, hollow articles or bars; General aspects of joining several hollow-preforms to form hollow or tubular articles
    • B29C66/51—Joining tubular articles, profiled elements or bars; Joining single elements to tubular articles, hollow articles or bars; Joining several hollow-preforms to form hollow or tubular articles
    • B29C66/53—Joining single elements to tubular articles, hollow articles or bars
    • B29C66/534—Joining single elements to open ends of tubular or hollow articles or to the ends of bars
    • B29C66/5346—Joining single elements to open ends of tubular or hollow articles or to the ends of bars said single elements being substantially flat
    • B29C66/53461—Joining single elements to open ends of tubular or hollow articles or to the ends of bars said single elements being substantially flat joining substantially flat covers and/or substantially flat bottoms to open ends of container bodies
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/80—General aspects of machine operations or constructions and parts thereof
    • B29C66/84—Specific machine types or machines suitable for specific applications
    • B29C66/843—Machines for making separate joints at the same time in different planes; Machines for making separate joints at the same time mounted in parallel or in series
    • B29C66/8432—Machines for making separate joints at the same time mounted in parallel or in series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C66/00—General aspects of processes or apparatus for joining preformed parts
    • B29C66/80—General aspects of machine operations or constructions and parts thereof
    • B29C66/84—Specific machine types or machines suitable for specific applications
    • B29C66/849—Packaging machines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/712—Containers; Packaging elements or accessories, Packages
    • B29L2031/7162—Boxes, cartons, cases
    • B29L2031/7164—Blister packages
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G01N2001/2833—Collecting samples on a sticky, tacky, adhesive surface
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Mechanical Engineering (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Description

【発明の詳細な説明】 〔産業上の利用分野〕 この発明は液体試料を化学的に分析測定する化
学分析スライドの製造方法に関するものである。
〔従来の技術〕
一般に、血液、血清等の液体試料について、当
該液体試料における特定の成分の含有の有無ある
いはその含有量等を知るべき場合に反応試薬によ
る化学分析が行われる。液体試料の化学分析法と
しては、乾式法と湿式法とがあるが、このうち乾
式法は、透明支持体の上面に試薬層を形成し、該
試薬層の上面に展開層を積層してなる化学分析フ
イルムを、その面積よりも小さい面積の開口をそ
れぞれ有する第一及び第二マウント間に介装した
スライドを用い、該スライドの第一マウントの開
口部より分析すべき液体試料を滴下して供給し、
これを反応用恒温槽内に置いて液体試料と試薬と
を反応せしめ、その反応の進行状態または結果
を、例えば反応による色の濃度変化を光学式濃度
測定器により測定する手段、その他の手段により
測定検出する方法であり、液体試料を実際上固体
として取り扱うことができる点で非常に便利であ
る。
ところが、従来の化学分析スライドは特開昭57
−63452号に代表される如く、化学分析フイルム
の面積よりも小さい面積の開口をそれぞれ有する
第一及び第二マウントと、これらの間に位置して
前記化学分析フイルムが収まる開口部を有する第
３部材（スペーサ）を別個に成形して組立ていた
ため、製造工程数の増大と、大掛りな設備を必要
とし、コスト高になるとの欠点があつた。
〔発明の目的・構成〕
この発明は上記の問題を解消するためのもの
で、連続するマウント基材の上面に凹状の絞込み
溝を形成し、該絞込み溝の各溝内に化学分析フイ
ルムを充填後、マウント基材の上面にマウントカ
バー基材を供給して接着し、マウント基材の非溝
部に相当する部分を長さ方向に沿つてスリツトす
るとともに、クロス状に断裁するという極めて単
純化した化学分析スライドの製造方法を提供する
ことを目的としている。
〔実施例〕
次に、この発明を添付図面に示す一実施例にも
とづいて説明する。
１は連続するマウント基材で、該マウント基材
１は原反リール２より引出ローラ３、テンシヨン
ローラ４、ガイドローラ５を介して引出され、図
示しない作業テーブル上を水平方向に走行するよ
うになつている。
６は上述の如く引出されたマウント基材１の上
面より下面側に向けて凹状に絞込むための絞込み
装置で、該絞込み装置６として図示の場合はプレ
ス成形器を示しているが、真空成形器あるいは圧
空成形器を利用することも可能であることは言う
までもない。この絞込み装置６により成形された
絞込み溝７の底面の中央領域には測光用の開口部
８（第４図参照）が穿孔されるが、この穿孔手段
は絞込み装置６自体に装置して絞込み溝７の形成
と同時に穿孔できるようにしても、絞込み装置６
の前段或いは後段にて専用の穿孔機（図示せず）
を用いて穿孔してもよいものである。
９は透明支持体の上面に試薬層を形成し、該試
薬層の上面に展開層を積層してなる化学分析フイ
ルム１０を上述の如く形成された絞込み溝７内に
充填する充填機である。該充填機９はその詳細が
図示されていないが、所定の大きさの化学分析フ
イルム１０を供給機（図示せず）より受けて列に
して各絞込み溝７の直上まで搬送し、真空吸着装
置の如き手段によりピツクアツプし、その吸着端
をクランクアームのような駆動手段により下降さ
せて化学分析フイルム１０を前記溝７内に充填す
るようになつていればよいものである。
１１はマウントカバー基材で、該マウントカバ
ー基材１１はリール１１′に巻設され、引出ロー
ラ１２を介して引出されるとともにガイドローラ
１３を経て化学分析フイルム１０が前記溝７内に
充填後のマウント基材１の上面に供給され、圧着
装置１４にて上述の如く絞込んだ溝７，７…間の
非溝部１５面に接着されるようになつている。こ
の接着手段は超音波溶着が一般的に採用される
が、容易に剥離されないように固着される他の接
着手段があればそれによつてもよい。
また、このマウントカバー基材１１には前記絞
込み溝７の中央領域に対応する位置に試料分注用
の開口部１７が予め穿孔されている。この穿孔位
置は前記絞込み装置６により成形された溝７の進
行速度とのタイミングをとることにより正確に一
致されることとなる。
１８はマウント基材１の上面にマウントカバー
基材を供給して接着した後、前記マウント基材１
の非溝部１５のほゞ中央に相当する部分を長さ方
向に沿つてスリツトするためのスリツタで、該ス
リツタ１８は回転刃を用いて満足できる。１９は
スリツタ１８によりスリツトされた後のマウント
基材１及びマウントカバー基材１１をクロス状に
断裁するためのクロスカツタで、該クロスカツタ
１９により第２図示の如くカツトすることによ
り、第３図，第４図示の如き製品２０が連続して
得られることとなる。
なお、図中２１は製品２０をラインより取出す
ための取出装置、２２はその置台である。
〔発明の効果〕
この発明は以上の如く連続するマウント基材の
上面に凹状の絞込み溝を形成し、該絞込み溝の各
溝内に化学分析フイルムを充填後、マウント基材
の上面にマウントカバー基材を供給して接着し、
マウント基材の非溝部に相当する部分を長さ方向
に沿つてスリツトするとともに、クロス状に断裁
することを特徴としているから、化学分析フイル
ムを装填した化学分析スライドが簡単かつ短時間
に製造でき、製造設備の単純化、コストの低廉化
が期待できるという優れた効果を奏するものであ
る。
【図面の簡単な説明】
第１図はこの発明を実施する装置の概略図、第
２図は製造過程の主要部を示す斜視図、第３図は
本方法により得られた化学分析スライドの一部切
欠平面図、第４図は同断面図である。 １……マウント基材、２……原反リール、６…
…絞込み装置、７……絞込み溝、９……充填機、
１０……化学分析フイルム、１１……マウントカ
バー基材、１５……非溝部、１８……スリツタ、
１９……クロスカツタ、２０……製品。

Claims (1)

    【特許請求の範囲】
  1. １ 連続するマウント基材の上面に凹状の絞込み
    部を形成し、該絞込み部の各溝内に化学分析フイ
    ルムを充填後、マウント基材の上面にマウントカ
    バー基材を供給して接着し、マウント基材の非溝
    部に相当する部分を長さ方向に沿つてスリツトす
    るとともに、クロス状に断裁することを特徴とす
    る化学分析スライドの製造方法。
JP58221126A 1983-11-24 1983-11-24 化学分析スライドの製造方法 Granted JPS60113133A (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP58221126A JPS60113133A (ja) 1983-11-24 1983-11-24 化学分析スライドの製造方法
US06/672,098 US4668472A (en) 1983-11-24 1984-11-15 Slide for chemical analysis
DE19843442820 DE3442820A1 (de) 1983-11-24 1984-11-23 Verfahren zur kontinuierlichen herstellung von objekttraegern und die dabei erhaltenen objekttraeger

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58221126A JPS60113133A (ja) 1983-11-24 1983-11-24 化学分析スライドの製造方法

Publications (2)

Publication Number Publication Date
JPS60113133A JPS60113133A (ja) 1985-06-19
JPH0254895B2 true JPH0254895B2 (ja) 1990-11-22

Family

ID=16761866

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58221126A Granted JPS60113133A (ja) 1983-11-24 1983-11-24 化学分析スライドの製造方法

Country Status (3)

Country Link
US (1) US4668472A (ja)
JP (1) JPS60113133A (ja)
DE (1) DE3442820A1 (ja)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3520847A1 (de) * 1985-06-11 1986-12-11 Miles Laboratories, Inc., Elkhart, Ind. Teststreifen und verfahren zur herstellung von teststreifen
US4719085A (en) * 1985-12-24 1988-01-12 Eastman Kodak Company Mount for ammonia-sensitive test elements
US4971912A (en) * 1987-07-14 1990-11-20 Technicon Instruments Corporation Apparatus and method for the separation of immiscible liquids
US4994238A (en) * 1988-06-09 1991-02-19 Daffern George M Constant volume chemical analysis test device
US5106758A (en) * 1988-12-12 1992-04-21 Technicon Instruments Corporation Analytical test device and the use thereof
US5053197A (en) * 1989-07-19 1991-10-01 Pb Diagnostic Systems, Inc. Diagnostic assay module
AU633965B2 (en) * 1989-09-08 1993-02-11 Terumo Kabushiki Kaisha Test instrument
US5008077A (en) * 1989-12-26 1991-04-16 Miles Inc. Easy handling reagent strip
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US4668472A (en) 1987-05-26
JPS60113133A (ja) 1985-06-19
DE3442820A1 (de) 1985-06-05

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