JPH0262556B2 - - Google Patents

Info

Publication number
JPH0262556B2
JPH0262556B2 JP59182442A JP18244284A JPH0262556B2 JP H0262556 B2 JPH0262556 B2 JP H0262556B2 JP 59182442 A JP59182442 A JP 59182442A JP 18244284 A JP18244284 A JP 18244284A JP H0262556 B2 JPH0262556 B2 JP H0262556B2
Authority
JP
Japan
Prior art keywords
acid
ester
syn isomer
group
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59182442A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60142994A (ja
Inventor
Takao Takatani
Hisashi Takasugi
Kiryo Tsuji
Toshuki Chiba
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB10699/77A external-priority patent/GB1600735A/en
Priority claimed from KR7802782A external-priority patent/KR820001285B1/ko
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS60142994A publication Critical patent/JPS60142994A/ja
Publication of JPH0262556B2 publication Critical patent/JPH0262556B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
JP59182442A 1977-03-14 1984-08-30 セフエム化合物 Granted JPS60142994A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GB10699/77 1977-03-14
GB10699/77A GB1600735A (en) 1977-03-14 1977-03-14 Cephem and cephem compounds and processes for preparation thereof
GB29245/77 1977-07-12
GB42315/77 1977-10-11
GB75/78 1978-01-03
KR7802782A KR820001285B1 (ko) 1977-03-14 1978-09-13 세펨화합물의 제조방법
KR1019820000231A KR830000455B1 (ko) 1977-03-14 1982-01-18 세펨화합물의 제조방법

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2916978A Division JPS53137988A (en) 1977-03-14 1978-03-14 Cephem and cepham compounds and process for their preparation

Related Child Applications (5)

Application Number Title Priority Date Filing Date
JP2193985A Division JPH0639464B2 (ja) 1977-03-14 1990-07-24 チアゾリル酢酸化合物
JP2193987A Division JPH0720947B2 (ja) 1977-03-14 1990-07-24 アミノチアゾリル酢酸類
JP2193988A Division JPH03115256A (ja) 1977-03-14 1990-07-24 酢酸誘導体
JP2193989A Division JPH03115288A (ja) 1977-03-14 1990-07-24 セフェム化合物またはその塩
JP2193986A Division JPH03135972A (ja) 1977-03-14 1990-07-24 チアゾリル酢酸類

Publications (2)

Publication Number Publication Date
JPS60142994A JPS60142994A (ja) 1985-07-29
JPH0262556B2 true JPH0262556B2 (it) 1990-12-26

Family

ID=27256566

Family Applications (3)

Application Number Title Priority Date Filing Date
JP59182442A Granted JPS60142994A (ja) 1977-03-14 1984-08-30 セフエム化合物
JP59182441A Granted JPS625988A (ja) 1977-03-14 1984-08-30 セフエムまたはセフアム化合物
JP59182443A Granted JPS60142971A (ja) 1977-03-14 1984-08-30 ７―置換―３―セフェム―４―カルボン酸化合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP59182441A Granted JPS625988A (ja) 1977-03-14 1984-08-30 セフエムまたはセフアム化合物
JP59182443A Granted JPS60142971A (ja) 1977-03-14 1984-08-30 ７―置換―３―セフェム―４―カルボン酸化合物

Country Status (5)

Country Link
JP (3) JPS60142994A (it)
KR (1) KR830000455B1 (it)
AU (1) AU520269B2 (it)
MY (1) MY8500906A (it)
ZA (1) ZA781502B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE878514A (fr) * 1978-09-04 1980-02-29 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
AR229883A1 (es) 1978-05-26 1983-12-30 Glaxo Group Ltd Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato
JPS5543089A (en) * 1978-09-12 1980-03-26 Fujisawa Pharmaceut Co Ltd Preparation of 3-cephem compound
JP6477735B2 (ja) 2017-01-26 2019-03-06 Ｊｆｅスチール株式会社 二相ステンレスクラッド鋼およびその製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
SE440655B (sv) * 1976-01-23 1985-08-12 Roussel Uclaf Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra
DE2716677C2 (de) * 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
KR830000455B1 (ko) 1983-03-08
JPS60142971A (ja) 1985-07-29
AU520269B2 (en) 1982-01-21
JPH0354953B2 (it) 1991-08-21
JPS625988A (ja) 1987-01-12
MY8500906A (en) 1985-12-31
ZA781502B (en) 1979-09-26
AU3413378A (en) 1979-09-20
JPH0254839B2 (it) 1990-11-22
JPS60142994A (ja) 1985-07-29

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