JPH03280953A - Medical label and medical vessel sticking it - Google Patents

Abstract

PURPOSE:To obtain a label, which is adhesively attached no more again when once exfoliated, by providing an intermediate layer, which generates interlayer- exfoliation by force smaller than the adhesive strength of an adhesive agent layer, between a sheet-shaped base material and the adhesive agent layer and molding the medical label. CONSTITUTION:A medical label 1 is prepared by providing an intermediate layer 3, which generates intralayer-exfoliation by force smaller than adhesive strength of an adhesive agent layer, between a sheet-shaped base material 2 and the adhesive agent layer 4. The medical label 1 is pasted to a sheet material 11 of a bag 10 by this adhesive agent layer 4. In the case of deliberately stripping the medical label 1, the base material 2 is exfoliated by causing intralayer- exfoliation to divide the intermediate layer 3. Here, the exfoliated label is prevented from being again adhesively attached as in the conventional label because of no exfoliation between the adhesive agent layer 4 and the sheet material 11 or between the intermediate layer 3 and the adhesive agent layer 4.

Description

[Detailed description of the invention]

<Industrial Application Field> The present invention relates to a medical label affixed to a medical container such as a blood bag or an infusion bag, and a medical container to which the label is affixed. <Prior Art> Labels are affixed to medical containers such as blood bags and infusion bags for various purposes. For example, a container label for displaying the amount of blood to be collected and the blood type (A, B, 0, RH, etc.) of the collected blood is affixed to the surface of the blood bag. Such container labels are made by applying a hot melt adhesive to the surface of a paper base material (Japanese Patent Laid-Open No. 1-11
(No. 8187) When the container label peels off due to moisture generated by condensation during sealed storage of an unused blood bag, or when it is intentionally peeled off, the main problem is that the gap between the adhesive layer and the bag surface is peeled off. Since the container label is peeled off, all or part of the adhesive layer remains and can be reapplied to another location. In this case, since the blood type is displayed on the container label, if it is mistakenly attached to another blood bag with a different blood type, there is a risk of an accident such as blood type incompatibility during blood transfusion. ,It is a danger. In addition, the adhesive layer of the label attached to the surface of blood bags, etc. has conventionally been used to contain organic solvents such as methyl ethyl ketone. Sometimes it got mixed into blood and infusion fluids. Even if the amount of organic solvent mixed in is small, it may be harmful to the human body, and this becomes a problem especially when large amounts of blood or fluids are transfused frequently. <Problems to be Solved by the Invention> The present invention has been made in view of the above-mentioned drawbacks of the prior art, and its purpose is to provide a medical label that does not adhere again after being peeled off, and a medical container to which the same is attached. Our goal is to provide the following. Furthermore, another object of the present invention is to provide a medical label and a medical container to which the label is affixed, in which organic solvents do not transfer to an object to which the label is affixed, particularly to the contents of a medical container such as a bag. There is a particular thing. <Means for Solving the Problems> Such objects are achieved by the following inventions (1) to (8). (1) A medical label having an intermediate layer between a sheet-like base material and an adhesive layer, wherein the intermediate layer causes intralayer peeling with a force smaller than the adhesive strength of the adhesive layer. A medical label characterized by: (2) The medical label according to (1) above, wherein the intermediate layer is composed of a uniaxially stretched polypropylene film containing an inorganic filler. (3) The thickness of the intermediate layer is 5 to 40μ (1)
) or the medical label described in (2). (4) The medical label according to any one of (1) to (3) above, wherein the adhesive layer is substantially free of organic solvent. (5) The medical label according to any one of (1) to (4) above, wherein the adhesive layer contains an acrylic copolymer as a main component. (6) The above (1) to (5), wherein a printing layer having printability is provided on the surface of the sheet-like base material opposite to the surface on which the intermediate layer is formed.
A medical label listed in any of the following. (7) The medical label according to (6) above, wherein the printing layer has water repellency. (8) A medical container to which the medical label according to any one of (1) to (7) above is attached. <Operation> According to the present invention having such a configuration, when the medical label is peeled off, the intermediate layer causes intralayer peeling, and a part of the divided intermediate layer is placed on the base material side of the medical label, and the remaining part is placed on the base material side of the medical label. It remains on the bag side together with the adhesive layer. Therefore, the medical label that has been peeled off will not stick to other places again or the labels will stick to each other, and traces of the medical label being peeled off will remain on the bag side (tamper proof).
, that fact can be easily recognized. This prevents the medical label displaying the blood type from peeling off from the blood bag and being erroneously attached to a liquid bag with a different blood type. In addition, if the adhesive layer of the medical label does not substantially contain organic solvents, harmful organic solvents may migrate into the contents of the blood bag, infusion bag, etc. to which the medical label is attached. Nor. <Configuration of the Invention> Hereinafter, the medical label of the present invention will be described in detail based on preferred embodiments shown in the accompanying drawings. The medical label 1 of the present invention is attached to the surface of a medical container, for example a bag 10 as shown in FIG. This bag 10 is a blood bag (blood collection bag).
Examples include red blood cell storage bags, platelet storage bags, plasma storage bags, and infusion bags (hereinafter referred to as blood bags). The bag 10 is constructed by stacking sheet materials 11 made of a flexible material such as soft polyvinyl chloride (PVC) or ethylene-vinyl acetate copolymer (EVA), and applying high-frequency heating or It is fused using other heating methods to form a bag. A liquid storage portion 13 is formed in the inner portion surrounded by the seal portion 12, in which collected blood or blood components thereof are stored. Furthermore, two outlets 14,14 with beer tabs are formed in the upper part of the bag 10, and a tube 15 communicating with the liquid storage part 13 of the bag 10 is connected between them. As shown in FIG. 2, the medical label 1 of the present invention has a sheet-like base material 2, and an intermediate layer 3 is formed on the lower surface side of the base material 2 in the figure. 3, an adhesive layer 4 is applied and formed on the lower surface. This adhesive layer 4
As a result, the medical label 1 is attached to the sheet material 11 of the bag 10. Further, a printed layer 5 is formed on the upper surface side of the base material 2 in the figure, if necessary. The base material 2 is mainly responsible for the strength and rigidity of the medical label 1, and may be paper, synthetic paper, or a resin film made of polypropylene, polystyrene, polyvinyl chloride, polyester, polystyrene, polyamide (nylon), etc. Can be mentioned. The thickness of the base material 2 is not particularly limited, but is preferably 15 to
It is about 1100 J, more preferably about 30 to 80 J. If it is less than 15μ, it will be too thin and will have high flexibility, which will cause problems in handling, and if it exceeds 100μ, it will be too thick and lack flexibility, making it difficult to handle (especially for label pasting work, etc.)
This is because it becomes a hindrance to the above. The intermediate layer 3 causes interlayer peeling with a force smaller than the adhesive strength of the adhesive layer 4 to the sheet material 11 (particularly the adhesive strength in a dry state of the label), which will be described later. As a result, when an attempt is made to peel off the medical label 1 intentionally, for example, as shown in FIG. 3, the intermediate layer 3 causes intralayer peeling and is divided, and the base material 2 is peeled off. In this case, there will be no separation between the adhesive layer 4 and the sheet material 11 or between the intermediate layer 3 and the adhesive layer 4, so that the peeled label will not be able to be bonded again, unlike conventional labels. Prevented. Moreover, the adhesive layer 4 and part of the divided intermediate layer 3 remain attached to the sheet material 11 of the bag 10, and traces of the medical label 1 being peeled off remain, so this fact is easily recognized. . Further, since a part of the divided intermediate layer 3 is attached to one side of the peeled base material 2 of the medical label and the adhesive layer 4 is not attached, there is an advantage that reattachment is not possible. As such an intermediate layer 3, polyolefins such as polybrobylene, polyethylene, polybutene, polystyrene, etc. are preferably used. In particular, as the intermediate layer 3, it is preferable to use a uniaxially stretched polypropylene film containing an inorganic filler. This material is especially directional, so medical labels 1
It also has the advantage that when it is intentionally peeled off, it is easy to peel off, and the tamper-proof property becomes clearer because it is torn. The inorganic filler is added mainly to adjust the intralayer peel strength, but it may also be added for other purposes such as improving paper quality, whitening, and improving compatibility with adhesives. Inorganic fillers include, for example, oxides such as silica, alumina, titanium oxide, and diatomaceous earth, hydroxides such as aluminum hydroxide and magnesium hydroxide, carbonates such as calcium carbonate, magnesium carbonate, and dawsonite, and calcium sulfate. , sulfates or sulfites such as barium sulfate and ammonium sulfate, talc, clay, mica, asbestos, glass, silicates such as calcium silicate, carbon such as carbon black and graphite, metals such as iron, copper, aluminum, titanium, etc. Examples include oxides thereof, among which calcium carbonate and clay talc are preferred. In addition, the forms of such inorganic fillers include powder, granular,
The plate-shaped filler may be any material such as fiber, but powder or granules are particularly preferred. In addition, when the inorganic filler is a powder or granular material, the particle size is 0.
．． It is preferably about 3 to 10 p. The amount of such an inorganic filler added to the intermediate layer 3 varies depending on the type of inorganic filler and the purpose of its addition, but if the main purpose is to adjust the intralayer peel strength of the intermediate layer 3, the amount added is , about 20 to 70% by weight, particularly preferably about 40 to 70% by weight. Further, other additives such as an antioxidant and a coloring agent may be added to the intermediate layer 3, for example. The thickness of such intermediate layer 3 is not particularly limited, but is preferably about 5 to 40 microns, more preferably about 10 to 25 microns. If the number is less than 5, intralayer peeling is unlikely to occur, and if it exceeds 40p, intralayer peeling is likely to occur, but it is therefore vulnerable to impact and may peel off due to a slight impact applied during product storage. The adhesive layer 4 may be made of any material as long as it has an affinity with the intermediate layer 3, such as hot melt adhesives, emulsion adhesives, various solvent adhesives, modified olefin adhesives, etc. Although it is possible, it is preferable to use one that does not substantially contain an organic solvent, especially when attaching it to bags. This is because with such an adhesive, the organic solvent does not pass through the sheet material 11 and transfer to the solution inside the bag 10. Here, adhesives that do not substantially contain organic solvents include:
Emulsion adhesives whose solvent is water are preferred, and those whose main component is an acrylic copolymer are particularly preferred.
The reason is that this material exhibits good pressure- and heat-sensitive reactivity. Examples of the acrylic copolymer used here include acrylic acid alkyl ester copolymer, acrylonitrile-acrylic acid alkyl ester copolymer, styrene-acrylic acid alkyl ester copolymer, styrene-methacrylic acid alkyl ester-acrylic Examples include acid alkyl ester copolymers. As a method of forming the adhesive layer 4, an emulsion mainly composed of an acrylic copolymer as described above is applied to the intermediate layer 3.
This is done by coating the underside of the Further, additives such as a thickener and an antistatic agent may be added to the adhesive layer 4, for example. The adhesive strength of the adhesive layer mainly composed of the above acrylic copolymer is 1 to 2 when a sample with a width of 15 m+n is subjected to a peel test at 300 mm/min using a tensile tester.
It is about kgf. The coating amount of the adhesive layer 4 is not particularly limited, but is preferably about 20 to 50 g/m'', more preferably about 25 to 35 g/m''. 20g/m
If it is less than 50 g/m2, it will result in poor adhesion.
This is because if it exceeds the temperature, it will take time to bond under heat and pressure, and the time during which the hot mold is in contact with the medical container will also increase, increasing the possibility of damage. The printing layer 5 is suitable for printing. That is, printing suitability means that the ink 6 has affinity with the ink 6 and that the printed ink 6 does not substantially cause peeling, transfer, chipping, etc. Moreover, it is preferable that the printed layer 5 has water repellency. That is, with conventional container labels, the printing may fall off due to moisture generated due to condensation while the unused bag 10 is stored in a sealed state, or moisture that adheres during use, or when characters are written on with a writing instrument. However, in the present invention, the printed layer 5 is repellent. If the material is water-based, it can prevent moisture from adhering to it, thereby preventing this problem. Furthermore, when the moisture adheres and penetrates, the adhesive strength of the adhesive layer 4 decreases, and when an attempt is made to peel off the medical label 1, the adhesive layer 4 becomes a sheet before intralayer peeling at the intermediate layer 3. Although there is a risk that the printed layer 5 will peel off from the material 11 and the above-mentioned tamper-proof property etc. will not be obtained, such a problem can be prevented by providing the printed layer 5 having water repellency. Note that even when the printed layer 5 is not provided, the same effect can be obtained as long as the base material 2 itself has water repellency. Examples of such a printed layer 5 include various resin films such as polyolefin, and those similar to the above intermediate layer 3 can also be used. Further, the printed layer 5 can also be formed by a coating method,
For example, acrylic acid alkyl ester-methacrylic acid alkyl ester copolymer emulsion, acrylic acid alkyl ester-methacrylic acid alkyl ester-styrene copolymer emulsion, vinylidene chloride emulsion,
A material obtained by coating and drying a silicone emulsion or the like may also be used. Although the boundaries between the printed layer 5, the base material 2, and the intermediate layer 3 are clearly shown in FIGS. , may become unclear due to denaturation or the like. Although the medical label of the present invention has been described above with reference to the configuration example shown in the drawings, the present invention is not limited thereto.In particular, regarding the structure of each layer, the illustrated four-layer structure or the three-layer structure excluding the printed layer 5 may be used. and any other desired layer, e.g. a protective layer,
A gas barrier layer or the like may be added at any position. Furthermore, the medical container to which the medical label of the present invention is attached is
The bag 10 is not limited to the above-mentioned bag 10, and any material such as a medicine bottle, a blood collection tube, etc., or a packaging material thereof may be used. <Example> Hereinafter, specific examples of the medical label of the present invention will be described. (Example 1) A four-layer medical label (size: 9
cm x 9 cm) was manufactured. The structure of each layer is as follows.匪 1 Material: Uniaxially stretched polypropylene containing 20 wt% of calcium carbonate powder (inorganic filler) with a particle size of 3. Luminous thickness: 20μ Material: Polypropylene film Thickness: 40μ Insect' 1 layer material 2 Uniaxially oriented polypropylene film containing 50 wt % of calcium carbonate powder (inorganic filler) with a particle size of 3-20 mm (thickness: 720 mm) 1 layer Composition: Styrene-acrylic acid alkyl ester-methacrylic acid alkyl ester copolymer formation method: Intermediate On the surface of the layer, an emulsion containing the above material as the main component and substantially free of organic solvents was applied, dry coating amount: 35 g/m'' (Example 2) No printing layer was provided, and the base material was The label was the same as Example 1, except that it was made of 60-mm paper. (Comparative Example) A two-layer medical label made by applying the following adhesive on one side of the same base material as in Example 1. (Size: 9c
mX 9 cm) was produced. Composition: Methyl methacrylate, butyl methacrylate-vinyl chloride-vinyl acetate copolymer Solvent: methyl ethyl ketone Coating amount: 35 g7m

[Experiment 1] The medical labels of Example 1.2 and Comparative Example thus obtained were each attached to the center of the body of the blood bag using a label sealer as shown in Figure 1, and then each label I peeled it off with my nails. In both of the medical labels of Examples 1 and 2, peeling occurred within the intermediate layer, and the intermediate layer was divided near the center in the thickness direction, so the adhesive remained on the blood bag side. was not exposed on the surface. On the other hand, in the medical label of the comparative example, the adhesive remained on both the base material side and the blood bag side, and the surface thereof was in a state where it was easy to stick.

[Experiment 2] The medical labels of Example 1.2 and Comparative Example above were attached to the center of the body of a blood bag made of a soft polyvinyl chloride sheet material with a thickness of 0.4 mm using a label sealer. Paste and add 28m of distilled water inside these blood bags.
1 was filled and sealed, and stored in an environment of 40°C for 30 days. Thereafter, the organic components eluted into the distilled water in each blood bag were analyzed using a gas chromatograph. In the blood bags with the medical labels of Examples 1 and 2, only trace amounts of plasticizer contained in the constituent materials of the bags were detected, whereas in the blood bags with the medical labels of Comparative Example, In addition to similar plasticizers, 2 ppm of methyl ethyl ketone, an organic solvent used in adhesives for medical labels, was detected in the blood bags that had been deposited. <Effects of the Invention> As described above, according to the present invention, a medical label that does not adhere again after being peeled off is provided. This prevents, for example, medical labels displaying blood types from peeling off and being erroneously attached to other blood bags with different blood types, causing accidents such as blood type incompatibility during blood transfusions. Further, when collecting and managing peeled off medical labels, the labels do not adhere to each other and cause handling problems. Additionally, if an adhesive that does not substantially contain organic solvents is used for medical labels, harmful organic solvents will not be transferred to the liquid inside blood bags, etc. to which the medical labels are attached. . In addition, when a water-repellent printing layer is provided, the water resistance of medical labels is improved, preventing the printing from falling off, maintaining writability, and preventing poor adhesion of small label labels. A decrease in strength can be prevented.

[Brief explanation of the drawing]

FIG. 1 is a plan view showing an example of the structure of the medical container of the present invention. FIG. 2 is an enlarged cross-sectional side view showing an example of the structure of the medical label of the present invention. FIG. 3 is an enlarged cross-sectional side view showing a state in which the medical label shown in FIG. 2 is peeled off. Explanation of symbols 1... Medical label 2... Base material 3... Intermediate layer 4... Adhesive layer 5... Printing layer 6... Ink 10... Bag 11... Sheet Material 12...Seal part 13...Liquid storage part 14...Discharge port 5...Tube applicant Almo stock% formula%

Claims (8)

[Claims] (1) A medical label having an intermediate layer between a sheet-like base material and an adhesive layer, wherein the intermediate layer causes intralayer peeling with a force smaller than the adhesive strength of the adhesive layer. A medical label characterized by: (2) The medical label according to claim 1, wherein the intermediate layer is composed of a uniaxially stretched polypropylene film containing an inorganic filler. (3) The medical label according to claim 1 or 2, wherein the intermediate layer has a thickness of 5 to 40 μm. (4) The medical label according to any one of claims 1 to 3, wherein the adhesive layer does not substantially contain an organic solvent. (5) The medical label according to any one of claims 1 to 4, wherein the adhesive layer contains an acrylic copolymer as a main component. (6) The medical label according to any one of claims 1 to 5, wherein a printing layer having printability is provided on the surface of the sheet-like base material opposite to the surface on which the intermediate layer is formed. (7) The medical label according to claim 6, wherein the printing layer has water repellency. (8) A medical container to which the medical label according to any one of claims 1 to 7 is attached.