JPH04264254A - 改良型電気泳動のための自動制御システム - Google Patents

改良型電気泳動のための自動制御システム

Info

Publication number: JPH04264254A
Authority: JP; Japan
Prior art keywords: size; switch time; macromolecule; electrophoresis; knowledge base
Prior art date: 1990-10-02
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

JP3255323A

Other languages

English (en)

Japanese (ja)

Inventor

Eric Lai

エリック　ライ

Bruce W Birren

ブルース　ダブリュ．バーレン

Will H Stubblebine

ウィル　エイチ．スタブルバイン

George E Bers

ジョージ　イー．バース

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bio Rad Laboratories Inc

Original Assignee

Bio Rad Laboratories Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-02

Filing date

1991-10-02

Publication date

1992-09-21

1991-10-02 Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc

1992-09-21 Publication of JPH04264254A publication Critical patent/JPH04264254A/ja

Status Pending legal-status Critical Current

Links

238000001962 electrophoresis Methods 0.000 title claims abstract description 31
238000000926 separation method Methods 0.000 claims abstract description 26
238000000034 method Methods 0.000 claims description 39
229920002521 macromolecule Polymers 0.000 claims description 30
238000012360 testing method Methods 0.000 claims description 6
230000037230 mobility Effects 0.000 claims 4
239000012634 fragment Substances 0.000 abstract description 23
230000005684 electric field Effects 0.000 abstract description 13
230000006870 function Effects 0.000 description 20
229920000936 Agarose Polymers 0.000 description 12
239000000499 gel Substances 0.000 description 11
238000013508 migration Methods 0.000 description 7
239000013598 vector Substances 0.000 description 7
238000001502 gel electrophoresis Methods 0.000 description 6
230000005012 migration Effects 0.000 description 6
238000012935 Averaging Methods 0.000 description 5
230000008569 process Effects 0.000 description 5
239000011543 agarose gel Substances 0.000 description 4
238000003906 pulsed field gel electrophoresis Methods 0.000 description 3
PIEPQKCYPFFYMG-UHFFFAOYSA-N tris acetate Chemical group CC(O)=O.OCC(N)(CO)CO PIEPQKCYPFFYMG-UHFFFAOYSA-N 0.000 description 3
235000021419 vinegar Nutrition 0.000 description 3
239000000052 vinegar Substances 0.000 description 3
208000003251 Pruritus Diseases 0.000 description 2
238000000354 decomposition reaction Methods 0.000 description 2
230000003247 decreasing effect Effects 0.000 description 2
238000010586 diagram Methods 0.000 description 2
230000000694 effects Effects 0.000 description 2
230000005611 electricity Effects 0.000 description 2
238000001472 pulsed field gradient Methods 0.000 description 2
238000000746 purification Methods 0.000 description 2
229920001817 Agar Polymers 0.000 description 1
206010010071 Coma Diseases 0.000 description 1
KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
240000004808 Saccharomyces cerevisiae Species 0.000 description 1
241001080526 Vertica Species 0.000 description 1
239000008272 agar Substances 0.000 description 1
238000013459 approach Methods 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
230000008859 change Effects 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
230000007423 decrease Effects 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
230000001419 dependent effect Effects 0.000 description 1
238000013213 extrapolation Methods 0.000 description 1
238000009499 grossing Methods 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
238000011005 laboratory method Methods 0.000 description 1
150000002605 large molecules Chemical class 0.000 description 1
239000011159 matrix material Substances 0.000 description 1
239000000203 mixture Substances 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004048 modification Effects 0.000 description 1
230000004044 response Effects 0.000 description 1
230000005476 size effect Effects 0.000 description 1
238000010561 standard procedure Methods 0.000 description 1
210000002784 stomach Anatomy 0.000 description 1
238000012546 transfer Methods 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
- B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44773—Multi-stage electrophoresis, e.g. two-dimensional electrophoresis

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Electrochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Environmental & Geological Engineering (AREA)
Engineering & Computer Science (AREA)
Investigating Or Analysing Biological Materials (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

JP3255323A 1990-10-02 1991-10-02 改良型電気泳動のための自動制御システム Pending JPH04264254A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US59158990A	1990-10-02	1990-10-02
US591589		1990-10-02

Publications (1)

Publication Number	Publication Date
JPH04264254A true JPH04264254A (ja)	1992-09-21

Family

ID=24367064

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP3255323A Pending JPH04264254A (ja)	1990-10-02	1991-10-02	改良型電気泳動のための自動制御システム

Country Status (6)

Country	Link
JP (1)	JPH04264254A (it)
CA (1)	CA2052037A1 (it)
DE (1)	DE4132694A1 (it)
FR (1)	FR2670683B1 (it)
GB (1)	GB2249395B (it)
IT (1)	IT1250936B (it)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2002521692A (ja) *	1998-07-31	2002-07-16	アボット・ラボラトリーズ	データ管理システムを含む被分析物検査器具システム
JP2007327969A (ja) *	2007-08-03	2007-12-20	Horiba Ltd	水質測定装置

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6574601A (en) *	2000-06-07	2001-12-17	Centro Nacional De Investigaciones Cientificas (Cnic)	Pulsed field electrophoresis chambers, accessories and method of utilization for seperation of DNA molecules
CU23095A1 (es)	2000-11-07	2005-11-18	Cnic Ct Nac Investigaciones	Proceso para la tipificación rápida de microorganismos y juego de reactivos empleado
US10337054B2 (en)	2004-02-02	2019-07-02	Quantum-Si Incorporated	Enrichment of nucleic acid targets
US8529744B2 (en)	2004-02-02	2013-09-10	Boreal Genomics Corp.	Enrichment of nucleic acid targets
US9186685B2 (en)	2012-01-13	2015-11-17	The University Of British Columbia	Multiple arm apparatus and methods for separation of particles
EP1720636A4 (en)	2004-02-02	2012-06-20	Univ British Columbia	SCODAPHORESIS AND METHOD AND DEVICES FOR MOVING AND CONCENTRATING PARTICLES
CA2496294A1 (en)	2005-02-07	2006-08-07	The University Of British Columbia	Apparatus and methods for concentrating and separating particles such as molecules
US8475641B2 (en)	2008-02-01	2013-07-02	The University Of British Columbia	Methods and apparatus for particle introduction and recovery
US8877028B2 (en)	2009-04-21	2014-11-04	The University Of British Columbia	System and methods for detection of particles
CA2742327A1 (en)	2011-05-20	2012-11-20	The University Of British Columiba	Systems and methods for enhanced scoda
WO2013166444A2 (en)	2012-05-04	2013-11-07	Boreal Genomics Corp.	Biomarker analysis using scodaphoresis
US9340835B2 (en)	2013-03-15	2016-05-17	Boreal Genomics Corp.	Method for separating homoduplexed and heteroduplexed nucleic acids
WO2016185284A1 (en)	2015-05-20	2016-11-24	Boreal Genomics, Inc.	Method for isolating target nucleic acid using heteroduplex binding proteins
US12011716B2 (en)	2019-10-29	2024-06-18	Quantum-Si Incorporated	Peristaltic pumping of fluids and associated methods, systems, and devices

Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH02176457A (ja) *	1988-09-15	1990-07-09	Carnegie Inst Of Washington	パルス志向電気泳動

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4771384A (en) *	1986-07-24	1988-09-13	Dnastar, Inc.	System and method for fragmentation mapping
CA2012379C (en) *	1989-04-24	2000-01-25	Gary W. Slater	Processes for the preparation and separation of macromolecules

1991
- 1991-09-23 CA CA002052037A patent/CA2052037A1/en not_active Abandoned
- 1991-10-01 FR FR9112066A patent/FR2670683B1/fr not_active Expired - Fee Related
- 1991-10-01 GB GB9120922A patent/GB2249395B/en not_active Expired - Fee Related
- 1991-10-01 DE DE4132694A patent/DE4132694A1/de not_active Withdrawn
- 1991-10-02 JP JP3255323A patent/JPH04264254A/ja active Pending
- 1991-10-02 IT ITRM910741A patent/IT1250936B/it active IP Right Grant

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH02176457A (ja) *	1988-09-15	1990-07-09	Carnegie Inst Of Washington	パルス志向電気泳動

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2002521692A (ja) *	1998-07-31	2002-07-16	アボット・ラボラトリーズ	データ管理システムを含む被分析物検査器具システム
JP4750276B2 (ja) *	1998-07-31	2011-08-17	アボット・ラボラトリーズ	データ管理システムを含む被分析物検査器具システム
JP2007327969A (ja) *	2007-08-03	2007-12-20	Horiba Ltd	水質測定装置

Also Published As

Publication number	Publication date
DE4132694A1 (de)	1992-04-16
ITRM910741A0 (it)	1991-10-02
GB9120922D0 (en)	1991-11-13
IT1250936B (it)	1995-04-22
GB2249395B (en)	1994-08-10
ITRM910741A1 (it)	1993-04-02
FR2670683B1 (fr)	1993-07-09
FR2670683A1 (fr)	1992-06-26
CA2052037A1 (en)	1992-04-03
GB2249395A (en)	1992-05-06

Publication	Publication Date	Title
JPH04264254A (ja)	1992-09-21	改良型電気泳動のための自動制御システム
Clark et al.	1988	A novel instrument for separating large DNA molecules with pulsed homogeneous electric fields
Cantor et al.	1988	Pulsed-field gel electrophoresis of very large DNA molecules
US4737251A (en)	1988-04-12	Field-inversion gel electrophoresis
Slater et al.	1988	Quantitative analysis of the three regimes of DNA electrophoresis in agarose gels
Diekmann et al.	1982	Electric properties and structure of DNA restriction fragments from measurements of the electric dichroism
US5165898A (en)	1992-11-24	Electrophoresis using contour-clamped electric fields
Finney	2000	Pulsed‐field gel electrophoresis
JPH087185B2 (ja)	1996-01-29	マクロ分子の調製および分離方法
Campos et al.	2019	The effects on neutral variability of recurrent selective sweeps and background selection
US5084157A (en)	1992-01-28	Gel electrophoresis using time dependent contour controlled electric fields
Birren et al.	1989	Pulsed field gel electrophoresis techniques for separating 1-to 50-kilobase DNA fragments
Righetti et al.	1997	Recent advances in capillary electrophoresis of DNA fragments and PCR products in poly (N-substituted acrylamides)
EP0644420A2 (en)	1995-03-22	Method and apparatus for gel electrophoresis
US4830726A (en)	1989-05-16	Separation of large DNA molecules in alternating asymmetric electric fields
US5549796A (en)	1996-08-27	Electrophoresis using contour-clamped electric fields
US5167790A (en)	1992-12-01	Field-inversion gel electrophoresis
US20050130157A1 (en)	2005-06-16	Electrophoretic ratchets and cyclic electrophoresis
US5178737A (en)	1993-01-12	Electrophoretic resolution of single strand DNA by asymmetric field inversion
NISHIGAKI et al.	1986	Detection of differences in higher order structure between highly homologous single-stranded DNAs by low-temperature denaturant gradient gel electrophoresis
Righetti et al.	1999	Capillary electrophoresis of DNA in the 20–500 bp range: recent developments
Pel	2009	A novel electrophoretic mechanism and separation parameter for selective nucleic acid concentration based on synchronous coefficient of drag alteration (SCODA)
Catai et al.	2003	Simplex optimization of electrokinetic injection of DNA in capillary electrophoresis using dilute polymer solution
Carle et al.	1992	Field-inversion gel electrophoresis
Kalfas et al.	1996	Flexibility and thermal denaturation (melting) of irradiated DNA