JPH04500602A - 合成ｈｉｖプロテアーゼ遺伝子およびその発現法 - Google Patents

合成ｈｉｖプロテアーゼ遺伝子およびその発現法

Info

Publication number
JPH04500602A
JPH04500602A JP1508775A JP50877589A JPH04500602A JP H04500602 A JPH04500602 A JP H04500602A JP 1508775 A JP1508775 A JP 1508775A JP 50877589 A JP50877589 A JP 50877589A JP H04500602 A JPH04500602 A JP H04500602A
Authority
JP
Japan
Prior art keywords
protease
gene
hiv
synthetic
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1508775A
Other languages
English (en)
Japanese (ja)
Inventor
ルイス，ジョン、エム
オロスラン，スティーブン
モラ，ピーター　ティー．
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Department of Commerce
Original Assignee
United States Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Department of Commerce filed Critical United States Department of Commerce
Publication of JPH04500602A publication Critical patent/JPH04500602A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP1508775A 1988-07-13 1989-07-13 合成ｈｉｖプロテアーゼ遺伝子およびその発現法 Pending JPH04500602A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21830488A 1988-07-13 1988-07-13
US218,304 1988-07-13

Publications (1)

Publication Number Publication Date
JPH04500602A true JPH04500602A (ja) 1992-02-06

Family

ID=22814563

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1508775A Pending JPH04500602A (ja) 1988-07-13 1989-07-13 合成ｈｉｖプロテアーゼ遺伝子およびその発現法

Country Status (6)

Country Link
EP (1) EP0425580A4 (fr)
JP (1) JPH04500602A (fr)
AU (1) AU635216B2 (fr)
CA (1) CA1340748C (fr)
IL (1) IL90947A (fr)
WO (1) WO1990000556A1 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599789A (en) * 1991-12-24 1997-02-04 Amrad Corporation Limited Method for the treatment of tumours and sarcomas
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
MXPA93002392A (es) 1992-03-11 2005-02-04 Narhex Ltd Derivados amino de hidrocarburos-oxo e hidroxi-substituidos.
JPH07504654A (ja) * 1992-03-11 1995-05-25 ナルヘックス　リミテッド オキソ及びヒドロキシ置換炭化水素のアミン誘導体
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US6001558A (en) * 1997-06-25 1999-12-14 Ortho Clinical Diagnostics, Inc. Amplification and detection of HIV-1 and/or HIV 2
JP4776075B2 (ja) 1998-12-31 2011-09-21 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド 改変ｈｉｖｅｎｖポリペプチド
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
AU2487300A (en) 1998-12-31 2000-07-31 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
AU2221600A (en) 1998-12-31 2000-07-31 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
CA2458995C (fr) 2001-08-31 2013-04-30 Chiron Corporation Polynucleotides codant des polypeptides de type b du vih antigeniques, polypeptides et leurs utilisations

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252477A (en) * 1987-06-01 1993-10-12 The United States Of America As Represented By The United States Department Of Health And Human Services Human immunodeficiency virus specific proteolytic enzyme and a method for its synthesis and renaturation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PRO.NATL.ACAD.SCI=1987US *

Also Published As

Publication number Publication date
CA1340748C (fr) 1999-09-14
WO1990000556A1 (fr) 1990-01-25
EP0425580A1 (fr) 1991-05-08
AU4058589A (en) 1990-02-05
IL90947A0 (en) 1990-02-09
AU635216B2 (en) 1993-03-18
EP0425580A4 (en) 1992-05-06
IL90947A (en) 1997-06-10

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