JPH0522686B2 - - Google Patents

Info

Publication number: JPH0522686B2
Authority: JP; Japan
Prior art keywords: cetraxate; formula; present; ointment; compound
Prior art date: 1984-07-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP15378284A

Other languages

English (en)

Japanese (ja)

Other versions

JPS6133116A (ja

Inventor

Takashi Yasue

Sadao Hirota

Mitsuhiko Chitoku

Masanori Fukui

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Daiichi Pharmaceutical Co Ltd

Original Assignee

Daiichi Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-07-24

Filing date

1984-07-24

Publication date

1993-03-30

1984-07-24 Application filed by Daiichi Pharmaceutical Co Ltd filed Critical Daiichi Pharmaceutical Co Ltd

1984-07-24 Priority to JP15378284A priority Critical patent/JPS6133116A/ja

1986-02-17 Publication of JPS6133116A publication Critical patent/JPS6133116A/ja

1993-03-30 Publication of JPH0522686B2 publication Critical patent/JPH0522686B2/ja

Status Granted legal-status Critical Current

Links

150000001875 compounds Chemical class 0.000 claims description 8
238000002360 preparation method Methods 0.000 claims description 7
208000017520 skin disease Diseases 0.000 claims description 4
150000003839 salts Chemical class 0.000 claims description 3
FHRSHSOEWXUORL-HDJSIYSDSA-N cetraxate Chemical compound C1C[C@@H](C[NH3+])CC[C@@H]1C(=O)OC1=CC=C(CCC([O-])=O)C=C1 FHRSHSOEWXUORL-HDJSIYSDSA-N 0.000 description 8
229950009533 cetraxate Drugs 0.000 description 8
239000002674 ointment Substances 0.000 description 8
238000009472 formulation Methods 0.000 description 7
239000000203 mixture Substances 0.000 description 7
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 6
GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 4
PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 4
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
-1 etc. can be used Substances 0.000 description 3
BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 3
235000019271 petrolatum Nutrition 0.000 description 3
206010012438 Dermatitis atopic Diseases 0.000 description 2
206010015150 Erythema Diseases 0.000 description 2
LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
208000007514 Herpes zoster Diseases 0.000 description 2
206010037575 Pustular psoriasis Diseases 0.000 description 2
235000021355 Stearic acid Nutrition 0.000 description 2
208000025865 Ulcer Diseases 0.000 description 2
201000008937 atopic dermatitis Diseases 0.000 description 2
229960000541 cetyl alcohol Drugs 0.000 description 2
239000006071 cream Substances 0.000 description 2
230000000694 effects Effects 0.000 description 2
231100000321 erythema Toxicity 0.000 description 2
IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
230000003902 lesion Effects 0.000 description 2
239000006210 lotion Substances 0.000 description 2
JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 2
GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 2
QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 2
OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 2
229940032094 squalane Drugs 0.000 description 2
239000008117 stearic acid Substances 0.000 description 2
208000024891 symptom Diseases 0.000 description 2
231100000397 ulcer Toxicity 0.000 description 2
239000003871 white petrolatum Substances 0.000 description 2
208000003322 Coinfection Diseases 0.000 description 1
201000004624 Dermatitis Diseases 0.000 description 1
208000007882 Gastritis Diseases 0.000 description 1
206010021531 Impetigo Diseases 0.000 description 1
206010061218 Inflammation Diseases 0.000 description 1
239000004166 Lanolin Substances 0.000 description 1
206010030113 Oedema Diseases 0.000 description 1
235000021314 Palmitic acid Nutrition 0.000 description 1
206010033733 Papule Diseases 0.000 description 1
201000011152 Pemphigus Diseases 0.000 description 1
108010047320 Pepsinogen A Proteins 0.000 description 1
239000004264 Petrolatum Substances 0.000 description 1
239000002202 Polyethylene glycol Substances 0.000 description 1
208000003251 Pruritus Diseases 0.000 description 1
241000700159 Rattus Species 0.000 description 1
HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 1
208000007107 Stomach Ulcer Diseases 0.000 description 1
208000002474 Tinea Diseases 0.000 description 1
241000893966 Trichophyton verrucosum Species 0.000 description 1
ZVQOOHYFBIDMTQ-UHFFFAOYSA-N [methyl(oxido){1-[6-(trifluoromethyl)pyridin-3-yl]ethyl}-lambda(6)-sulfanylidene]cyanamide Chemical compound N#CN=S(C)(=O)C(C)C1=CC=C(C(F)(F)F)N=C1 ZVQOOHYFBIDMTQ-UHFFFAOYSA-N 0.000 description 1
230000004913 activation Effects 0.000 description 1
150000001298 alcohols Chemical class 0.000 description 1
230000003110 anti-inflammatory effect Effects 0.000 description 1
230000000288 anti-kallikrein effect Effects 0.000 description 1
208000010668 atopic eczema Diseases 0.000 description 1
208000005035 cutaneous candidiasis Diseases 0.000 description 1
235000014113 dietary fatty acids Nutrition 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
LQZZUXJYWNFBMV-UHFFFAOYSA-N dodecan-1-ol Chemical compound CCCCCCCCCCCCO LQZZUXJYWNFBMV-UHFFFAOYSA-N 0.000 description 1
239000002552 dosage form Substances 0.000 description 1
239000003814 drug Substances 0.000 description 1
238000001035 drying Methods 0.000 description 1
238000005562 fading Methods 0.000 description 1
239000000194 fatty acid Substances 0.000 description 1
229930195729 fatty acid Natural products 0.000 description 1
150000004665 fatty acids Chemical class 0.000 description 1
210000004051 gastric juice Anatomy 0.000 description 1
210000001156 gastric mucosa Anatomy 0.000 description 1
150000002334 glycols Chemical class 0.000 description 1
230000035876 healing Effects 0.000 description 1
229930195733 hydrocarbon Natural products 0.000 description 1
150000002430 hydrocarbons Chemical class 0.000 description 1
208000015181 infectious disease Diseases 0.000 description 1
230000004054 inflammatory process Effects 0.000 description 1
230000007803 itching Effects 0.000 description 1
229940039717 lanolin Drugs 0.000 description 1
235000019388 lanolin Nutrition 0.000 description 1
229940057995 liquid paraffin Drugs 0.000 description 1
229960003511 macrogol Drugs 0.000 description 1
238000000034 method Methods 0.000 description 1
210000004877 mucosa Anatomy 0.000 description 1
WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
231100000957 no side effect Toxicity 0.000 description 1
239000003921 oil Substances 0.000 description 1
235000014593 oils and fats Nutrition 0.000 description 1
239000003002 pH adjusting agent Substances 0.000 description 1
201000001976 pemphigus vulgaris Diseases 0.000 description 1
239000002304 perfume Substances 0.000 description 1
229940066842 petrolatum Drugs 0.000 description 1
230000000144 pharmacologic effect Effects 0.000 description 1
239000000049 pigment Substances 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000001737 promoting effect Effects 0.000 description 1
239000008213 purified water Substances 0.000 description 1
201000010914 pustulosis of palm and sole Diseases 0.000 description 1
208000011797 pustulosis palmaris et plantaris Diseases 0.000 description 1
230000028327 secretion Effects 0.000 description 1
229940012831 stearyl alcohol Drugs 0.000 description 1
230000003637 steroidlike Effects 0.000 description 1
239000004094 surface-active agent Substances 0.000 description 1
210000004243 sweat Anatomy 0.000 description 1
TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
229940124597 therapeutic agent Drugs 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
239000003860 topical agent Substances 0.000 description 1
230000000699 topical effect Effects 0.000 description 1
229940099259 vaseline Drugs 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
239000001993 wax Substances 0.000 description 1

Landscapes

Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

JP15378284A 1984-07-24 1984-07-24 皮膚疾患用外用剤 Granted JPS6133116A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP15378284A JPS6133116A (ja)	1984-07-24	1984-07-24	皮膚疾患用外用剤

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP15378284A JPS6133116A (ja)	1984-07-24	1984-07-24	皮膚疾患用外用剤

Publications (2)

Publication Number	Publication Date
JPS6133116A JPS6133116A (ja)	1986-02-17
JPH0522686B2 true JPH0522686B2 (de)	1993-03-30

Family

ID=15570019

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP15378284A Granted JPS6133116A (ja)	1984-07-24	1984-07-24	皮膚疾患用外用剤

Country Status (1)

Country	Link
JP (1)	JPS6133116A (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2110176A1 (en) *	1992-03-28	1993-10-14	Akira Yanagawa	Topical preparation for healing wounds of the skin
KR940702481A (ko) *	1992-07-22	1994-08-20	후쿠하라 요시하루	트라넥삼산(tranexamic acid)유도체 및 그것을 배합한 피부외용제(TRANEXAMIC ACID DERIVATIVE AND DERMATOLOGIC PREPARATION CONTAINING THE SAME)

1984
- 1984-07-24 JP JP15378284A patent/JPS6133116A/ja active Granted

Also Published As

Publication number	Publication date
JPS6133116A (ja)	1986-02-17

Publication	Publication Date	Title
US4610978A (en)	1986-09-09	Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same
US6096326A (en)	2000-08-01	Skin care compositions and use
ES2319699T3 (es)	2009-05-11	Remedio para la rosacea.
JPH0714873B2 (ja)	1995-02-22	局所性製薬組成物
EP0229654B1 (de)	1995-01-04	Behandlung von nicht-Akne-entzündlichen und -infektiösen Hautkrankheiten
GB1594314A (en)	1981-07-30	Medicine for the treatment of acne
EP1147086B1 (de)	2005-03-30	Zusammensetzungen zur behandlung von hautkrankheiten
KR960016205B1 (ko)	1996-12-06	피부질환 및 종양치료를 위한 약제 조성물
KR20080086515A (ko)	2008-09-25	알칸디카르복실산 및 레티노이드의 장미증 및 다른 염증성피부 질환 치료를 위한 용도
CA2742389A1 (en)	2010-04-08	Topical treatment of skin infection
EP0561766B1 (de)	1995-11-02	Verwendung von essentiellen fettsäuren zur herstellung eines medikaments zur behandlung von ekzemen
JP4243353B2 (ja)	2009-03-25	皮膚疾患の治療に用いる共役リノール酸の亜鉛塩
JPH042571B2 (de)	1992-01-20
EP0352826B1 (de)	1994-10-26	Verwendung von 5-Amino-salicylsäure für die Behandlung von Hautkrankheiten
DE4022815A1 (de)	1992-01-23	Topische verwendung von (omega)-3-fettsaeuren-zubereitungen fuer hauterkrankungen
ES2880437T3 (es)	2021-11-24	Nuevas composiciones tópicas que comprenden ácido úsnico y su uso terapéutico
JPH0522686B2 (de)	1993-03-30
ES2379474T3 (es)	2012-04-26	Producto dermatológico para el tratamiento y/o cuidado de la piel con neurodermitis
RU2233152C1 (ru)	2004-07-27	Крем противовоспалительного и противозудного действия для лечения дерматологических заболеваний
Semkina	2005	Ointments, gels, liniments, and creams containing phytopreparations (a review)
JPH10139669A (ja)	1998-05-26	脂漏性角化症治療剤
JP2005515204A (ja)	2005-05-26	局所適用かゆみ止め製剤およびその調製方法
NZ205587A (en)	1986-08-08	Composition comprising undecylenic acid for treating herpes simplex i
JPH0259519A (ja)	1990-02-28	皮膚炎症治療剤
RU2742411C1 (ru)	2021-02-05	Противопсориатическая косметическая композиция в виде геля