JPH05501062A - Hiv―1のウイルス性コンプレックス抗原に結合する組換え蛋白質 - Google Patents
Hiv―1のウイルス性コンプレックス抗原に結合する組換え蛋白質Info
- Publication number
- JPH05501062A JPH05501062A JP3509464A JP50946491A JPH05501062A JP H05501062 A JPH05501062 A JP H05501062A JP 3509464 A JP3509464 A JP 3509464A JP 50946491 A JP50946491 A JP 50946491A JP H05501062 A JPH05501062 A JP H05501062A
- Authority
- JP
- Japan
- Prior art keywords
- protein
- sc3d6
- chain
- antibody
- recombinant protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—RNA viruses
- C07K16/112—Retroviridae (F), e.g. leukemia viruses
- C07K16/114—Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
- C07K16/1145—Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/22—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a Strep-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0117890A AT396939B (de) | 1990-05-29 | 1990-05-29 | Komplexes virales antigen von hiv-1 bindendes rekombinantes protein |
| AT1178/90 | 1990-05-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH05501062A true JPH05501062A (ja) | 1993-03-04 |
Family
ID=3508299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3509464A Pending JPH05501062A (ja) | 1990-05-29 | 1991-05-28 | Hiv―1のウイルス性コンプレックス抗原に結合する組換え蛋白質 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0484500A1 (de) |
| JP (1) | JPH05501062A (de) |
| AT (1) | AT396939B (de) |
| CA (1) | CA2064710A1 (de) |
| SK (1) | SK160391A3 (de) |
| WO (1) | WO1991018983A1 (de) |
| YU (1) | YU114691A (de) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994026895A1 (fr) * | 1993-05-10 | 1994-11-24 | Japan Tobacco Inc. | Gene vh d'immunoglobuline humaine et fragment d'adn contenant ce gene |
| US6096878A (en) * | 1993-05-10 | 2000-08-01 | Japan Tobacco Inc. | Human immunoglobulin VH gene segments and DNA fragments containing the same |
| US6936705B1 (en) | 1993-05-10 | 2005-08-30 | Japan Tobacco Inc. | Human immunoglobulin VH gene segments and DNA fragments containing the same |
| JP2008542278A (ja) * | 2005-05-27 | 2008-11-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Tweak結合抗体 |
| US8440189B2 (en) | 1999-01-15 | 2013-05-14 | Biogen Idec Ma Inc. | Antagonists of TWEAK and of TWEAK receptor and their use to treat immunological disorders |
| US9011859B2 (en) | 2002-04-09 | 2015-04-21 | Biogen Idec Ma Inc. | Methods for treating TWEAK-related conditions |
| US9730947B2 (en) | 2005-06-13 | 2017-08-15 | Biogen Ma Inc. | Method of treating lupus nephritis |
| US9775899B2 (en) | 2005-02-17 | 2017-10-03 | Biogen Ma Inc. | Treating neurological disorders |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU655878B2 (en) * | 1992-03-30 | 1995-01-12 | Daiichi Suntory Pharma Co., Ltd | Anti-HBs antibody gene and expression plasmid thereof |
| JP2003527116A (ja) * | 2000-03-15 | 2003-09-16 | インサイト・ゲノミックス・インコーポレイテッド | ヒト免疫応答タンパク質 |
| CA2607697C (en) | 2005-05-10 | 2015-01-06 | Biogen Idec Ma Inc. | Treating and evaluating inflammatory disorders |
| JP2010528583A (ja) * | 2007-06-11 | 2010-08-26 | エーシー イミューン ソシエテ アノニム | アミロイドβに対するヒト化抗体 |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| US8048420B2 (en) | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| EP2586795B1 (de) | 2007-10-05 | 2018-05-16 | Genentech, Inc. | Verwendung eines Anti-Amyloid-Beta-Antikörpers bei Augenkrankheiten |
| JP5646457B2 (ja) | 2008-04-29 | 2014-12-24 | アッヴィ・インコーポレイテッド | 二重可変ドメイン免疫グロブリン及びその使用 |
| AR072000A1 (es) | 2008-06-03 | 2010-07-28 | Abbott Lab | Proteinas de union multivalentes con capacidad de unir dos o mas antigenos y usos de la misma |
| KR20120060877A (ko) | 2009-09-01 | 2012-06-12 | 아보트 러보러터리즈 | 이원 가변 도메인 면역글로불린 및 이의 용도 |
| TW201119676A (en) | 2009-10-15 | 2011-06-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| UY32979A (es) | 2009-10-28 | 2011-02-28 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| MY164579A (en) | 2010-07-30 | 2018-01-15 | Ac Immune Sa | Safe and functional humanized antibodies |
| EP3252072A3 (de) | 2010-08-03 | 2018-03-14 | AbbVie Inc. | Immunglobuline mit zweifacher variabler domäne und verwendungen davon |
| SG187938A1 (en) | 2010-08-26 | 2013-04-30 | Abbvie Inc | Dual variable domain immunoglobulins and uses thereof |
| CN104159920A (zh) | 2011-12-30 | 2014-11-19 | 艾伯维公司 | 针对il-13和/或il-17的双重可变结构域免疫球蛋白 |
| MY171664A (en) | 2012-11-01 | 2019-10-22 | Abbvie Inc | Anti-dll4/vegf dual variable domain immunoglobulins and uses thereof |
| JP2016522793A (ja) | 2013-03-15 | 2016-08-04 | アッヴィ・インコーポレイテッド | IL−1βおよび/またはIL−17に対して指向された二重特異的結合タンパク質 |
| WO2016094881A2 (en) | 2014-12-11 | 2016-06-16 | Abbvie Inc. | Lrp-8 binding proteins |
| TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4851341A (en) * | 1986-12-19 | 1989-07-25 | Immunex Corporation | Immunoaffinity purification system |
| PT88641B (pt) * | 1987-10-02 | 1993-04-30 | Genentech Inc | Metodo para a preparacao de uma variante de adesao |
| EP0312164A1 (de) * | 1987-10-16 | 1989-04-19 | Merck & Co. Inc. | Reinigung von rekombinanten Epstein-Barr-Virusantigenen von Vero-, Hefe- oder L-Zellen |
| ATE135743T1 (de) * | 1987-11-13 | 1996-04-15 | Hermann Katinger | Monoklonale menschliche antikörper gegen hiv-i |
-
1990
- 1990-05-29 AT AT0117890A patent/AT396939B/de not_active IP Right Cessation
-
1991
- 1991-05-28 CA CA002064710A patent/CA2064710A1/en not_active Abandoned
- 1991-05-28 EP EP91910271A patent/EP0484500A1/de not_active Withdrawn
- 1991-05-28 JP JP3509464A patent/JPH05501062A/ja active Pending
- 1991-05-28 WO PCT/AT1991/000067 patent/WO1991018983A1/de not_active Ceased
- 1991-05-28 YU YU114691A patent/YU114691A/sh unknown
- 1991-05-29 SK SK1603-91A patent/SK160391A3/sk unknown
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994026895A1 (fr) * | 1993-05-10 | 1994-11-24 | Japan Tobacco Inc. | Gene vh d'immunoglobuline humaine et fragment d'adn contenant ce gene |
| US6096878A (en) * | 1993-05-10 | 2000-08-01 | Japan Tobacco Inc. | Human immunoglobulin VH gene segments and DNA fragments containing the same |
| US6936705B1 (en) | 1993-05-10 | 2005-08-30 | Japan Tobacco Inc. | Human immunoglobulin VH gene segments and DNA fragments containing the same |
| US8440189B2 (en) | 1999-01-15 | 2013-05-14 | Biogen Idec Ma Inc. | Antagonists of TWEAK and of TWEAK receptor and their use to treat immunological disorders |
| US9011859B2 (en) | 2002-04-09 | 2015-04-21 | Biogen Idec Ma Inc. | Methods for treating TWEAK-related conditions |
| US9775899B2 (en) | 2005-02-17 | 2017-10-03 | Biogen Ma Inc. | Treating neurological disorders |
| JP2008542278A (ja) * | 2005-05-27 | 2008-11-27 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Tweak結合抗体 |
| JP2017025105A (ja) * | 2005-05-27 | 2017-02-02 | バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. | Tweak結合抗体 |
| US9730947B2 (en) | 2005-06-13 | 2017-08-15 | Biogen Ma Inc. | Method of treating lupus nephritis |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2064710A1 (en) | 1991-11-30 |
| AT396939B (de) | 1993-12-27 |
| ATA117890A (de) | 1993-05-15 |
| WO1991018983A1 (de) | 1991-12-12 |
| SK160391A3 (en) | 1995-07-11 |
| EP0484500A1 (de) | 1992-05-13 |
| YU114691A (sh) | 1994-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPH05501062A (ja) | Hiv―1のウイルス性コンプレックス抗原に結合する組換え蛋白質 | |
| ES2334184T3 (es) | Metodo de identificacion de dominios de sitios de union que conservan la capacidad de unirse a un epitopo. | |
| JP4386741B2 (ja) | scDbライブラリーの作成方法 | |
| AU657788B2 (en) | Chimaeric interleukin 5-receptor/immunoglobulin polypeptides | |
| RU2744274C1 (ru) | Моноклональное антитело к RBD фрагменту в составе S белка вируса SARS-CoV-2 | |
| JP2018510623A (ja) | Nkg2d及び腫瘍関連抗原に対する二価抗体 | |
| WO2000020460A1 (en) | Methods for producing human tumor antigen specific antibodies | |
| JP2004537952A (ja) | 多重特異的結合分子とその使用 | |
| WO1996019584A1 (en) | Chimeric antibodies comprising antigen binding sites and b and t cell epitopes | |
| JP2007231027A (ja) | 癌マーカー用生物合成結合蛋白質 | |
| Kurucz et al. | A bacterially expressed single-chain Fv construct from the 2B4 T-cell receptor. | |
| KR102453605B1 (ko) | 신규 펩타이드 태그, 이에 결합하는 항체 및 이들의 용도 | |
| JPH11510375A (ja) | ペプチド−mhc複合体を指向するファージディスプレイライブラリーからの組換え抗体 | |
| KR20210143096A (ko) | Cd22에 특이적인 항체 및 이의 용도 | |
| EP1033406A1 (de) | Induktor zur herstellung antigen-spezifischer antikörper, expressionsvektor enthaltend ein hierfür entsprechendes gen, sowie verfahren zur induktion der herstellung eines antigen-spezifischen antikörpers | |
| KR102829757B1 (ko) | 인간화된 cd22에 특이적인 항체 및 이를 이용한 키메라 항원 수용체 | |
| JP2000508881A (ja) | 免疫グロブリン遺伝子の再編成されたゲノム可変領域のpcr増幅 | |
| JPH10110000A (ja) | 分泌Mac−2結合糖タンパク質 | |
| KR20220122844A (ko) | Cd22에 특이적인 인간화 항체 및 이의 용도 | |
| KR20150002588A (ko) | 인터페론 및 면역글로불린 fc 섹션 융합 단백질 | |
| KR100467706B1 (ko) | B형 간염 바이러스의 표면 항원에 대한 인간항체 | |
| CN116444665A (zh) | 针对新冠病毒SARS-CoV-2糖蛋白RBD区域的单克隆抗体及其应用 | |
| CN113683692A (zh) | SARS-CoV-2 N蛋白抗体及其应用 | |
| CN120518757B (zh) | 一种聚乙二醇化多价抗西尼罗病毒单链抗体 | |
| CN111876476A (zh) | 用于扩增马抗体的巢式pcr引物、试剂盒及其应用 |