JPH05501062A - Hiv―1のウイルス性コンプレックス抗原に結合する組換え蛋白質 - Google Patents

Hiv―1のウイルス性コンプレックス抗原に結合する組換え蛋白質

Info

Publication number
JPH05501062A
JPH05501062A JP3509464A JP50946491A JPH05501062A JP H05501062 A JPH05501062 A JP H05501062A JP 3509464 A JP3509464 A JP 3509464A JP 50946491 A JP50946491 A JP 50946491A JP H05501062 A JPH05501062 A JP H05501062A
Authority
JP
Japan
Prior art keywords
protein
sc3d6
chain
antibody
recombinant protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3509464A
Other languages
English (en)
Japanese (ja)
Inventor
ユングバウエル・アロイス
カティンゲル・ヘルマン
リューケル・フローリアン
フエルゲンハウエル・マルティン
ヒンムレル・ゴットフリート
コール・ヨハン
シュタインドル・フランツ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPH05501062A publication Critical patent/JPH05501062A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10RNA viruses
    • C07K16/112Retroviridae (F), e.g. leukemia viruses
    • C07K16/114Lentivirus (G), e.g. human immunodeficiency virus [HIV], feline immunodeficiency virus [FIV] or simian immunodeficiency virus [SIV]
    • C07K16/1145Env proteins, e.g. gp41, gp110/120, gp160, V3, principal neutralising domain [PND] or CD4-binding site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/22Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a Strep-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP3509464A 1990-05-29 1991-05-28 Hiv―1のウイルス性コンプレックス抗原に結合する組換え蛋白質 Pending JPH05501062A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0117890A AT396939B (de) 1990-05-29 1990-05-29 Komplexes virales antigen von hiv-1 bindendes rekombinantes protein
AT1178/90 1990-05-29

Publications (1)

Publication Number Publication Date
JPH05501062A true JPH05501062A (ja) 1993-03-04

Family

ID=3508299

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3509464A Pending JPH05501062A (ja) 1990-05-29 1991-05-28 Hiv―1のウイルス性コンプレックス抗原に結合する組換え蛋白質

Country Status (7)

Country Link
EP (1) EP0484500A1 (de)
JP (1) JPH05501062A (de)
AT (1) AT396939B (de)
CA (1) CA2064710A1 (de)
SK (1) SK160391A3 (de)
WO (1) WO1991018983A1 (de)
YU (1) YU114691A (de)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026895A1 (fr) * 1993-05-10 1994-11-24 Japan Tobacco Inc. Gene vh d'immunoglobuline humaine et fragment d'adn contenant ce gene
US6096878A (en) * 1993-05-10 2000-08-01 Japan Tobacco Inc. Human immunoglobulin VH gene segments and DNA fragments containing the same
US6936705B1 (en) 1993-05-10 2005-08-30 Japan Tobacco Inc. Human immunoglobulin VH gene segments and DNA fragments containing the same
JP2008542278A (ja) * 2005-05-27 2008-11-27 バイオジェン・アイデック・エムエイ・インコーポレイテッド Tweak結合抗体
US8440189B2 (en) 1999-01-15 2013-05-14 Biogen Idec Ma Inc. Antagonists of TWEAK and of TWEAK receptor and their use to treat immunological disorders
US9011859B2 (en) 2002-04-09 2015-04-21 Biogen Idec Ma Inc. Methods for treating TWEAK-related conditions
US9730947B2 (en) 2005-06-13 2017-08-15 Biogen Ma Inc. Method of treating lupus nephritis
US9775899B2 (en) 2005-02-17 2017-10-03 Biogen Ma Inc. Treating neurological disorders

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU655878B2 (en) * 1992-03-30 1995-01-12 Daiichi Suntory Pharma Co., Ltd Anti-HBs antibody gene and expression plasmid thereof
JP2003527116A (ja) * 2000-03-15 2003-09-16 インサイト・ゲノミックス・インコーポレイテッド ヒト免疫応答タンパク質
CA2607697C (en) 2005-05-10 2015-01-06 Biogen Idec Ma Inc. Treating and evaluating inflammatory disorders
JP2010528583A (ja) * 2007-06-11 2010-08-26 エーシー イミューン ソシエテ アノニム アミロイドβに対するヒト化抗体
US8613923B2 (en) 2007-06-12 2013-12-24 Ac Immune S.A. Monoclonal antibody
US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
EP2586795B1 (de) 2007-10-05 2018-05-16 Genentech, Inc. Verwendung eines Anti-Amyloid-Beta-Antikörpers bei Augenkrankheiten
JP5646457B2 (ja) 2008-04-29 2014-12-24 アッヴィ・インコーポレイテッド 二重可変ドメイン免疫グロブリン及びその使用
AR072000A1 (es) 2008-06-03 2010-07-28 Abbott Lab Proteinas de union multivalentes con capacidad de unir dos o mas antigenos y usos de la misma
KR20120060877A (ko) 2009-09-01 2012-06-12 아보트 러보러터리즈 이원 가변 도메인 면역글로불린 및 이의 용도
TW201119676A (en) 2009-10-15 2011-06-16 Abbott Lab Dual variable domain immunoglobulins and uses thereof
UY32979A (es) 2009-10-28 2011-02-28 Abbott Lab Inmunoglobulinas con dominio variable dual y usos de las mismas
MY164579A (en) 2010-07-30 2018-01-15 Ac Immune Sa Safe and functional humanized antibodies
EP3252072A3 (de) 2010-08-03 2018-03-14 AbbVie Inc. Immunglobuline mit zweifacher variabler domäne und verwendungen davon
SG187938A1 (en) 2010-08-26 2013-04-30 Abbvie Inc Dual variable domain immunoglobulins and uses thereof
CN104159920A (zh) 2011-12-30 2014-11-19 艾伯维公司 针对il-13和/或il-17的双重可变结构域免疫球蛋白
MY171664A (en) 2012-11-01 2019-10-22 Abbvie Inc Anti-dll4/vegf dual variable domain immunoglobulins and uses thereof
JP2016522793A (ja) 2013-03-15 2016-08-04 アッヴィ・インコーポレイテッド IL−1βおよび/またはIL−17に対して指向された二重特異的結合タンパク質
WO2016094881A2 (en) 2014-12-11 2016-06-16 Abbvie Inc. Lrp-8 binding proteins
TW201710286A (zh) 2015-06-15 2017-03-16 艾伯維有限公司 抗vegf、pdgf及/或其受體之結合蛋白

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851341A (en) * 1986-12-19 1989-07-25 Immunex Corporation Immunoaffinity purification system
PT88641B (pt) * 1987-10-02 1993-04-30 Genentech Inc Metodo para a preparacao de uma variante de adesao
EP0312164A1 (de) * 1987-10-16 1989-04-19 Merck & Co. Inc. Reinigung von rekombinanten Epstein-Barr-Virusantigenen von Vero-, Hefe- oder L-Zellen
ATE135743T1 (de) * 1987-11-13 1996-04-15 Hermann Katinger Monoklonale menschliche antikörper gegen hiv-i

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026895A1 (fr) * 1993-05-10 1994-11-24 Japan Tobacco Inc. Gene vh d'immunoglobuline humaine et fragment d'adn contenant ce gene
US6096878A (en) * 1993-05-10 2000-08-01 Japan Tobacco Inc. Human immunoglobulin VH gene segments and DNA fragments containing the same
US6936705B1 (en) 1993-05-10 2005-08-30 Japan Tobacco Inc. Human immunoglobulin VH gene segments and DNA fragments containing the same
US8440189B2 (en) 1999-01-15 2013-05-14 Biogen Idec Ma Inc. Antagonists of TWEAK and of TWEAK receptor and their use to treat immunological disorders
US9011859B2 (en) 2002-04-09 2015-04-21 Biogen Idec Ma Inc. Methods for treating TWEAK-related conditions
US9775899B2 (en) 2005-02-17 2017-10-03 Biogen Ma Inc. Treating neurological disorders
JP2008542278A (ja) * 2005-05-27 2008-11-27 バイオジェン・アイデック・エムエイ・インコーポレイテッド Tweak結合抗体
JP2017025105A (ja) * 2005-05-27 2017-02-02 バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. Tweak結合抗体
US9730947B2 (en) 2005-06-13 2017-08-15 Biogen Ma Inc. Method of treating lupus nephritis

Also Published As

Publication number Publication date
CA2064710A1 (en) 1991-11-30
AT396939B (de) 1993-12-27
ATA117890A (de) 1993-05-15
WO1991018983A1 (de) 1991-12-12
SK160391A3 (en) 1995-07-11
EP0484500A1 (de) 1992-05-13
YU114691A (sh) 1994-06-10

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